{"id":"https://openalex.org/W4406327282","doi":"https://doi.org/10.3390/v17010087","title":"The Dissemination of Rift Valley Fever Virus to the Eye and Sensory Neurons of Zebrafish Larvae Is Stat1-Dependent","display_name":"The Dissemination of Rift Valley Fever Virus to the Eye and Sensory Neurons of Zebrafish Larvae Is Stat1-Dependent","publication_year":2025,"publication_date":"2025-01-11","ids":{"openalex":"https://openalex.org/W4406327282","doi":"https://doi.org/10.3390/v17010087","pmid":"https://pubmed.ncbi.nlm.nih.gov/39861877","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11768566"},"language":"en","primary_location":{"id":"doi:10.3390/v17010087","doi":"https://doi.org/10.3390/v17010087","is_oa":true,"landing_page_url":"https://doi.org/10.3390/v17010087","pdf_url":"https://www.mdpi.com/1999-4915/17/1/87/pdf?version=1736605397","source":{"id":"https://openalex.org/S55776271","display_name":"Viruses","issn_l":"1999-4915","issn":["1999-4915"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Viruses","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1999-4915/17/1/87/pdf?version=1736605397","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034531528","display_name":"Sebastiaan ter Horst","orcid":"https://orcid.org/0000-0001-7981-6376","observed_orcids":["https://orcid.org/0000-0001-7981-6376"]},"institutions":[{"id":"https://openalex.org/I24156275","display_name":"Rega Institute for Medical Research","ror":"https://ror.org/03w5j8p12","country_code":"BE","type":"facility","lineage":["https://openalex.org/I24156275"]},{"id":"https://openalex.org/I99464096","display_name":"KU Leuven","ror":"https://ror.org/05f950310","country_code":"BE","type":"education","lineage":["https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"S. ter Horst","raw_affiliation_strings":["Laboratory for Virology and Chemotherapy, Rega Institute for Medical Research, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium","Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Herestraat 49, 3000 Leuven, Belgium"],"raw_orcid":"https://orcid.org/0000-0001-7981-6376","affiliations":[{"raw_affiliation_string":"Laboratory for Virology and Chemotherapy, Rega Institute for Medical Research, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium","institution_ids":["https://openalex.org/I24156275","https://openalex.org/I99464096"]},{"raw_affiliation_string":"Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Herestraat 49, 3000 Leuven, Belgium","institution_ids":["https://openalex.org/I24156275","https://openalex.org/I99464096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080234805","display_name":"Aleksandra Siekierska","orcid":"https://orcid.org/0000-0003-4907-605X","observed_orcids":["https://orcid.org/0000-0003-4907-605X"]},"institutions":[{"id":"https://openalex.org/I99464096","display_name":"KU Leuven","ror":"https://ror.org/05f950310","country_code":"BE","type":"education","lineage":["https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"A. Siekierska","raw_affiliation_strings":["Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium","Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Herestraat 49, 3000 Leuven, Belgium","VirusBank Platform, Gaston Geenslaan 3, 3001 Leuven, Belgium"],"raw_orcid":"https://orcid.org/0000-0003-4907-605X","affiliations":[{"raw_affiliation_string":"Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium","institution_ids":["https://openalex.org/I99464096"]},{"raw_affiliation_string":"Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Herestraat 49, 3000 Leuven, Belgium","institution_ids":["https://openalex.org/I99464096"]},{"raw_affiliation_string":"VirusBank Platform, Gaston Geenslaan 3, 3001 Leuven, Belgium","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090362329","display_name":"Ann\u2010Sofie De Meulemeester","orcid":"https://orcid.org/0000-0001-8490-5816","observed_orcids":["https://orcid.org/0000-0001-8490-5816"]},"institutions":[{"id":"https://openalex.org/I99464096","display_name":"KU Leuven","ror":"https://ror.org/05f950310","country_code":"BE","type":"education","lineage":["https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"AS. De Meulemeester","raw_affiliation_strings":["Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium","Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Herestraat 49, 3000 Leuven, Belgium"],"raw_orcid":"https://orcid.org/0000-0001-8490-5816","affiliations":[{"raw_affiliation_string":"Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium","institution_ids":["https://openalex.org/I99464096"]},{"raw_affiliation_string":"Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Herestraat 49, 3000 Leuven, Belgium","institution_ids":["https://openalex.org/I99464096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072156762","display_name":"Arno Cuvry","orcid":"https://orcid.org/0000-0002-8360-9510","observed_orcids":["https://orcid.org/0000-0002-8360-9510"]},"institutions":[{"id":"https://openalex.org/I24156275","display_name":"Rega Institute for Medical Research","ror":"https://ror.org/03w5j8p12","country_code":"BE","type":"facility","lineage":["https://openalex.org/I24156275"]},{"id":"https://openalex.org/I99464096","display_name":"KU Leuven","ror":"https://ror.org/05f950310","country_code":"BE","type":"education","lineage":["https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"A. Cuvry","raw_affiliation_strings":["Laboratory for Virology and Chemotherapy, Rega Institute for Medical Research, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium","Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Herestraat 49, 3000 Leuven, Belgium"],"raw_orcid":"https://orcid.org/0000-0002-8360-9510","affiliations":[{"raw_affiliation_string":"Laboratory for Virology and Chemotherapy, Rega Institute for Medical Research, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium","institution_ids":["https://openalex.org/I24156275","https://openalex.org/I99464096"]},{"raw_affiliation_string":"Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Herestraat 49, 3000 Leuven, Belgium","institution_ids":["https://openalex.org/I24156275","https://openalex.org/I99464096"]}]},{"author_position":"middle","author":{"id":null,"display_name":"L. Cools","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24156275","display_name":"Rega Institute for Medical Research","ror":"https://ror.org/03w5j8p12","country_code":"BE","type":"facility","lineage":["https://openalex.org/I24156275"]},{"id":"https://openalex.org/I99464096","display_name":"KU Leuven","ror":"https://ror.org/05f950310","country_code":"BE","type":"education","lineage":["https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"L. Cools","raw_affiliation_strings":["Laboratory for Virology and Chemotherapy, Rega Institute for Medical Research, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium","Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Herestraat 49, 3000 Leuven, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory for Virology and Chemotherapy, Rega Institute for Medical Research, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium","institution_ids":["https://openalex.org/I24156275","https://openalex.org/I99464096"]},{"raw_affiliation_string":"Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Herestraat 49, 3000 Leuven, Belgium","institution_ids":["https://openalex.org/I24156275","https://openalex.org/I99464096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089010495","display_name":"Johan H. Neyts","orcid":"https://orcid.org/0000-0002-0033-7514","observed_orcids":["https://orcid.org/0000-0002-0033-7514"]},"institutions":[{"id":"https://openalex.org/I24156275","display_name":"Rega Institute for Medical Research","ror":"https://ror.org/03w5j8p12","country_code":"BE","type":"facility","lineage":["https://openalex.org/I24156275"]},{"id":"https://openalex.org/I99464096","display_name":"KU Leuven","ror":"https://ror.org/05f950310","country_code":"BE","type":"education","lineage":["https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"J. Neyts","raw_affiliation_strings":["Laboratory for Virology and Chemotherapy, Rega Institute for Medical Research, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium","Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Herestraat 49, 3000 Leuven, Belgium"],"raw_orcid":"https://orcid.org/0000-0002-0033-7514","affiliations":[{"raw_affiliation_string":"Laboratory for Virology and Chemotherapy, Rega Institute for Medical Research, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium","institution_ids":["https://openalex.org/I24156275","https://openalex.org/I99464096"]},{"raw_affiliation_string":"Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Herestraat 49, 3000 Leuven, Belgium","institution_ids":["https://openalex.org/I24156275","https://openalex.org/I99464096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010582324","display_name":"Peter A.M. de Witte","orcid":"https://orcid.org/0000-0002-9989-9567","observed_orcids":["https://orcid.org/0000-0002-9989-9567"]},"institutions":[{"id":"https://openalex.org/I99464096","display_name":"KU Leuven","ror":"https://ror.org/05f950310","country_code":"BE","type":"education","lineage":["https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":true,"raw_author_name":"P. de Witte","raw_affiliation_strings":["Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium","Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Herestraat 49, 3000 Leuven, Belgium"],"raw_orcid":"https://orcid.org/0000-0002-9989-9567","affiliations":[{"raw_affiliation_string":"Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium","institution_ids":["https://openalex.org/I99464096"]},{"raw_affiliation_string":"Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Herestraat 49, 3000 Leuven, Belgium","institution_ids":["https://openalex.org/I99464096"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036604415","display_name":"Joana Rocha\u2010Pereira","orcid":"https://orcid.org/0000-0001-8299-3787","observed_orcids":["https://orcid.org/0000-0001-8299-3787"]},"institutions":[{"id":"https://openalex.org/I24156275","display_name":"Rega Institute for Medical Research","ror":"https://ror.org/03w5j8p12","country_code":"BE","type":"facility","lineage":["https://openalex.org/I24156275"]},{"id":"https://openalex.org/I99464096","display_name":"KU Leuven","ror":"https://ror.org/05f950310","country_code":"BE","type":"education","lineage":["https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":true,"raw_author_name":"J. Rocha-Pereira","raw_affiliation_strings":["Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium","Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Herestraat 49, 3000 Leuven, Belgium"],"raw_orcid":"https://orcid.org/0000-0001-8299-3787","affiliations":[{"raw_affiliation_string":"Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium","institution_ids":["https://openalex.org/I99464096"]},{"raw_affiliation_string":"Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Herestraat 49, 3000 Leuven, Belgium","institution_ids":["https://openalex.org/I24156275","https://openalex.org/I99464096"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5010582324","https://openalex.org/A5036604415"],"corresponding_institution_ids":["https://openalex.org/I24156275","https://openalex.org/I99464096"],"apc_list":{"value":2600,"currency":"CHF","value_usd":3137},"apc_paid":{"value":2600,"currency":"CHF","value_usd":3137},"fwci":2.2886,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.84539897,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"17","issue":"1","first_page":"87","last_page":"87"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12047","display_name":"Viral Infections and Vectors","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12047","display_name":"Viral Infections and Vectors","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11581","display_name":"Viral Infections and Outbreaks Research","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rift-valley-fever-virus","display_name":"Rift Valley fever virus","score":0.9990000128746033},{"id":"https://openalex.org/keywords/zebrafish-larvae","display_name":"zebrafish larvae","score":0.8479999899864197},{"id":"https://openalex.org/keywords/stat1","display_name":"STAT1","score":0.7070000171661377},{"id":"https://openalex.org/keywords/viral-dissemination","display_name":"viral dissemination","score":0.5509999990463257},{"id":"https://openalex.org/keywords/sensory-neurons","display_name":"sensory neurons","score":0.6809999942779541},{"id":"https://openalex.org/keywords/optic-tectum","display_name":"optic tectum","score":0.9120000004768372},{"id":"https://openalex.org/keywords/retina","display_name":"retina","score":0.968999981880188},{"id":"https://openalex.org/keywords/blindness","display_name":"blindness","score":0.8799999952316284},{"id":"https://openalex.org/keywords/jak-inhibition","display_name":"JAK inhibition","score":0.7020000219345093},{"id":"https://openalex.org/keywords/ruxolitinib","display_name":"ruxolitinib","score":0.9980000257492065},{"id":"https://openalex.org/keywords/antiviral-therapy","display_name":"antiviral therapy","score":0.6919999718666077},{"id":"https://openalex.org/keywords/viral-pathogenesis","display_name":"viral pathogenesis","score":0.6669999957084656},{"id":"https://openalex.org/keywords/in-vivo-infection-model","display_name":"in vivo infection model","score":0.5770000219345093}],"concepts":[{"id":"https://openalex.org/C2778960357","wikidata":"https://www.wikidata.org/wiki/Q326638","display_name":"Rift Valley fever","level":3,"score":0.8160438537597656},{"id":"https://openalex.org/C2776878037","wikidata":"https://www.wikidata.org/wiki/Q169444","display_name":"Zebrafish","level":3,"score":0.8058371543884277},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.679949164390564},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.6048083305358887},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.4746197760105133},{"id":"https://openalex.org/C140704245","wikidata":"https://www.wikidata.org/wiki/Q3933202","display_name":"Viral replication","level":3,"score":0.41544950008392334},{"id":"https://openalex.org/C94487597","wikidata":"https://www.wikidata.org/wiki/Q11101","display_name":"Sensory system","level":2,"score":0.411000519990921},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.3741886615753174},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3533499836921692},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.297510027885437},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.27376967668533325},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.14772331714630127},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12991991639137268}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005123","descriptor_name":"Eye","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D007814","descriptor_name":"Larva","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D011720","descriptor_name":"Pyrazoles","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011984","descriptor_name":"Sensory Receptor Cells","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D012295","descriptor_name":"Rift Valley Fever","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012295","descriptor_name":"Rift Valley Fever","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D012296","descriptor_name":"Rift Valley fever virus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D012296","descriptor_name":"Rift Valley fever virus","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true},{"descriptor_ui":"D012296","descriptor_name":"Rift Valley fever virus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D050794","descriptor_name":"STAT1 Transcription Factor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D050794","descriptor_name":"STAT1 Transcription Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.3390/v17010087","doi":"https://doi.org/10.3390/v17010087","is_oa":true,"landing_page_url":"https://doi.org/10.3390/v17010087","pdf_url":"https://www.mdpi.com/1999-4915/17/1/87/pdf?version=1736605397","source":{"id":"https://openalex.org/S55776271","display_name":"Viruses","issn_l":"1999-4915","issn":["1999-4915"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Viruses","raw_type":"journal-article"},{"id":"doi:10.1101/2022.08.10.503461","doi":"https://doi.org/10.1101/2022.08.10.503461","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2022.08.10.503461","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2022/08/12/2022.08.10.503461.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:11768566","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11768566","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11768566/pdf/viruses-17-00087.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Viruses","raw_type":"Text"},{"id":"pmid:39861877","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39861877","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Viruses","raw_type":"Journal Article"},{"id":"pmh:oai:lirias2repo.kuleuven.be:20.500.12942/759124","doi":null,"is_oa":true,"landing_page_url":"https://lirias.kuleuven.be/handle/20.500.12942/759124","pdf_url":"https://lirias.kuleuven.be/retrieve/557b4c7f-2711-403b-a7ed-0893ce642923","source":{"id":"https://openalex.org/S7407055369","display_name":"Lirias","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Viruses-Basel, vol. 17 (1), Art.No. ARTN 87","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:38928ed4353a47c299731f7fdddf3fb0","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/38928ed4353a47c299731f7fdddf3fb0","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Viruses, Vol 17, Iss 1, p 87 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/v17010087","doi":"https://doi.org/10.3390/v17010087","is_oa":true,"landing_page_url":"https://doi.org/10.3390/v17010087","pdf_url":"https://www.mdpi.com/1999-4915/17/1/87/pdf?version=1736605397","source":{"id":"https://openalex.org/S55776271","display_name":"Viruses","issn_l":"1999-4915","issn":["1999-4915"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Viruses","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8048999905586243}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3610188177","display_name":null,"funder_award_id":"O6260","funder_id":"https://openalex.org/F4320321730","funder_display_name":"Fonds Wetenschappelijk Onderzoek"},{"id":"https://openalex.org/G4250907147","display_name":"Unraveling the susceptibility and pathogenesis of viral infections using zebrafish","funder_award_id":"C24/18/080","funder_id":"https://openalex.org/F4320327336","funder_display_name":"Vlaamse regering"},{"id":"https://openalex.org/G7107182940","display_name":null,"funder_award_id":"C24/18/080","funder_id":"https://openalex.org/F4320322308","funder_display_name":"KU Leuven"},{"id":"https://openalex.org/G7578051358","display_name":"Modeling of human mTORopathies in zebrafish resulting from loss-of-function of its inhibitory regulators","funder_award_id":"11F2919N","funder_id":"https://openalex.org/F4320321730","funder_display_name":"Fonds Wetenschappelijk Onderzoek"},{"id":"https://openalex.org/G8457263807","display_name":null,"funder_award_id":"FWO; 11F2919N","funder_id":"https://openalex.org/F4320322308","funder_display_name":"KU Leuven"}],"funders":[{"id":"https://openalex.org/F4320321730","display_name":"Fonds Wetenschappelijk Onderzoek","ror":"https://ror.org/03qtxy027"},{"id":"https://openalex.org/F4320322308","display_name":"KU Leuven","ror":"https://ror.org/05f950310"},{"id":"https://openalex.org/F4320327336","display_name":"Vlaamse regering","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4406327282.pdf","grobid_xml":"https://content.openalex.org/works/W4406327282.grobid-xml"},"referenced_works_count":62,"referenced_works":["https://openalex.org/W1615535881","https://openalex.org/W1666139110","https://openalex.org/W1915704240","https://openalex.org/W1968215930","https://openalex.org/W1976391205","https://openalex.org/W1980353886","https://openalex.org/W1981239255","https://openalex.org/W1986777823","https://openalex.org/W1993251152","https://openalex.org/W1993550681","https://openalex.org/W1994391392","https://openalex.org/W1997369934","https://openalex.org/W2002534437","https://openalex.org/W2018354976","https://openalex.org/W2027413681","https://openalex.org/W2035509260","https://openalex.org/W2048630989","https://openalex.org/W2051313084","https://openalex.org/W2051636160","https://openalex.org/W2052318661","https://openalex.org/W2061881258","https://openalex.org/W2070238522","https://openalex.org/W2079738171","https://openalex.org/W2081877272","https://openalex.org/W2093165200","https://openalex.org/W2106753580","https://openalex.org/W2107277218","https://openalex.org/W2115198211","https://openalex.org/W2115756207","https://openalex.org/W2122326839","https://openalex.org/W2130847821","https://openalex.org/W2140367720","https://openalex.org/W2149891361","https://openalex.org/W2150573104","https://openalex.org/W2160633059","https://openalex.org/W2205290261","https://openalex.org/W2285139664","https://openalex.org/W2529441459","https://openalex.org/W2567337431","https://openalex.org/W2597942947","https://openalex.org/W2613478440","https://openalex.org/W2620563240","https://openalex.org/W2735720719","https://openalex.org/W2806145644","https://openalex.org/W2896796431","https://openalex.org/W2912175826","https://openalex.org/W2921091936","https://openalex.org/W2958578463","https://openalex.org/W2974070365","https://openalex.org/W2989166679","https://openalex.org/W2999229314","https://openalex.org/W3045323147","https://openalex.org/W3080402824","https://openalex.org/W3096143071","https://openalex.org/W3108931658","https://openalex.org/W3148705775","https://openalex.org/W3150998561","https://openalex.org/W3154989344","https://openalex.org/W3171325432","https://openalex.org/W4220680626","https://openalex.org/W4301391300","https://openalex.org/W4306765470"],"related_works":["https://openalex.org/W2112895001","https://openalex.org/W4301391300","https://openalex.org/W3003771002","https://openalex.org/W7204164934","https://openalex.org/W4394908719","https://openalex.org/W2899411212","https://openalex.org/W4306765470","https://openalex.org/W1995119224","https://openalex.org/W2034218628","https://openalex.org/W4384296889"],"abstract_inverted_index":{"Abstract":[0],"The":[1,60],"Rift":[2],"Valley":[3],"fever":[4],"virus":[5],"(RVFV)":[6],"is":[7],"listed":[8],"by":[9,57],"the":[10,64,72,79,86,101,108,145,149],"WHO":[11],"as":[12,114,116],"priority":[13],"disease":[14],"and":[15,20,27,74,82,103,135],"causes":[16],"haemorrhagic":[17],"fever,":[18],"encephalitis,":[19],"permanent":[21],"blindness.":[22],"To":[23],"study":[24],"RVFV":[25,44,69,125,155],"pathogenesis":[26],"identify":[28],"small-molecule":[29],"antivirals,":[30],"we":[31],"established":[32],"a":[33],"novel":[34],"in":[35,46,71,154],"vivo":[36],"model":[37],"using":[38],"zebrafish":[39],"larvae.":[40],"Pericardial":[41],"injection":[42],"of":[43,63,68,118,152],"resulted":[45],"~":[47,128],"4":[48],"log":[49,130],"10":[50,131],"viral":[51,132],"RNA":[52,133],"copies/larva,":[53],"which":[54],"was":[55],"inhibited":[56],"antiviral":[58],"2\u2032-fluoro-2\u2032-deoxycytidine.":[59],"optical":[61],"transparency":[62],"larvae":[65],"allowed":[66],"detection":[67],"eGFP":[70],"liver":[73],"sensory":[75,142],"nervous":[76],"system,":[77],"including":[78],"optic":[80],"tectum":[81],"retina,":[83],"but":[84,120],"not":[85,121],"brain":[87],"or":[88,144],"spinal":[89],"cord.":[90],"Thus,":[91],"RVFV-induced":[92],"blindness":[93],"likely":[94],"occurs":[95],"due":[96],"to":[97,100,127,141],"direct":[98],"damage":[99],"eye":[102],"peripheral":[104],"neurons,":[105],"rather":[106],"than":[107],"brain.":[109],"Treatment":[110],"with":[111],"JAK-inhibitor":[112],"ruxolitinib,":[113],"well":[115],"knockout":[117],"stat1a":[119],"stat1b":[122],",":[123],"enhanced":[124],"replication":[126],"6":[129],"copies/larva":[134],"ultra-bright":[136],"livers,":[137],"although":[138],"without":[139],"dissemination":[140],"neurons":[143],"eye,":[146],"hereby":[147],"confirming":[148],"critical":[150],"role":[151],"stat1":[153],"pathogenesis.":[156]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2025-01-14T00:00:00"}