{"id":"https://openalex.org/W4406305575","doi":"https://doi.org/10.33549/physiolres.935491","title":"New Possibilities of the Prevention and Treatment of Cardiovascular Pathologies. The Potential of Molecular Hydrogen in the Reduction of Oxidative Stress and its Consequences","display_name":"New Possibilities of the Prevention and Treatment of Cardiovascular Pathologies. The Potential of Molecular Hydrogen in the Reduction of Oxidative Stress and its Consequences","publication_year":2024,"publication_date":"2024-12-31","ids":{"openalex":"https://openalex.org/W4406305575","doi":"https://doi.org/10.33549/physiolres.935491","pmid":"https://pubmed.ncbi.nlm.nih.gov/39808170","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11827053"},"language":"en","primary_location":{"id":"doi:10.33549/physiolres.935491","doi":"https://doi.org/10.33549/physiolres.935491","is_oa":true,"landing_page_url":"https://doi.org/10.33549/physiolres.935491","pdf_url":"https://doi.org/10.33549/physiolres.935491","source":{"id":"https://openalex.org/S4210199525","display_name":"Physiological Research","issn_l":"0862-8408","issn":["0862-8408","1802-9973"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","medline","norway-1","oarl","poland-40","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310314155","host_organization_name":"Institute of Physiology of the Czech Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310314155","https://openalex.org/P4310314171"],"host_organization_lineage_names":["Institute of Physiology of the Czech Academy of Sciences","Czech Academy of Sciences"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiological Research","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.33549/physiolres.935491","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037626786","display_name":"J\u00e1n Slez\u00e1k","orcid":"https://orcid.org/0000-0002-4217-4493","observed_orcids":["https://orcid.org/0000-0002-4217-4493"]},"institutions":[{"id":"https://openalex.org/I207624831","display_name":"Slovak Academy of Sciences","ror":"https://ror.org/03h7qq074","country_code":"SK","type":"government","lineage":["https://openalex.org/I207624831"]},{"id":"https://openalex.org/I4210143440","display_name":"Centre of Experimental Medicine of the Slovak Academy of Sciences","ror":"https://ror.org/0380mmw63","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210143440"]},{"id":"https://openalex.org/I4405256417","display_name":"Institute for Heart Research of the Slovak Academy of Sciences","ror":"https://ror.org/044mjtc47","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210143440","https://openalex.org/I4405256417"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"J Slez\u00e1k","raw_affiliation_strings":["Centre of Experimental Medicine, Institute for Heart Research, Slovak Academy of Sciences, Bratislava, Slovak Republic. jan.slezak@savba.sk"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre of Experimental Medicine, Institute for Heart Research, Slovak Academy of Sciences, Bratislava, Slovak Republic. jan.slezak@savba.sk","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4210143440","https://openalex.org/I4405256417"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069004321","display_name":"T Rav\u00edngerov\u00e1","orcid":"https://orcid.org/0000-0002-8804-6964","observed_orcids":["https://orcid.org/0000-0002-8804-6964"]},"institutions":[{"id":"https://openalex.org/I207624831","display_name":"Slovak Academy of Sciences","ror":"https://ror.org/03h7qq074","country_code":"SK","type":"government","lineage":["https://openalex.org/I207624831"]},{"id":"https://openalex.org/I4210143440","display_name":"Centre of Experimental Medicine of the Slovak Academy of Sciences","ror":"https://ror.org/0380mmw63","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210143440"]},{"id":"https://openalex.org/I4405256417","display_name":"Institute for Heart Research of the Slovak Academy of Sciences","ror":"https://ror.org/044mjtc47","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210143440","https://openalex.org/I4405256417"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"T Ravingerov\u00e1","raw_affiliation_strings":["Centre of Experimental Medicine , Institute for Heart Research , Slovak Academy of Sciences , Bratislava , Slovak Republic","Centre of Experimental Medicine , Institute for Heart Research , Slovak Academy of Sciences , D\u00fabravsk\u00e1 cesta 9 , 841 04 Bratislava , Slovak Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre of Experimental Medicine , Institute for Heart Research , Slovak Academy of Sciences , Bratislava , Slovak Republic","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4210143440","https://openalex.org/I4405256417"]},{"raw_affiliation_string":"Centre of Experimental Medicine , Institute for Heart Research , Slovak Academy of Sciences , D\u00fabravsk\u00e1 cesta 9 , 841 04 Bratislava , Slovak Republic","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4210143440","https://openalex.org/I4405256417"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049356678","display_name":"Branislav Kura","orcid":"https://orcid.org/0000-0001-6743-491X","observed_orcids":["https://orcid.org/0000-0001-6743-491X"]},"institutions":[{"id":"https://openalex.org/I207624831","display_name":"Slovak Academy of Sciences","ror":"https://ror.org/03h7qq074","country_code":"SK","type":"government","lineage":["https://openalex.org/I207624831"]},{"id":"https://openalex.org/I4210143440","display_name":"Centre of Experimental Medicine of the Slovak Academy of Sciences","ror":"https://ror.org/0380mmw63","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210143440"]},{"id":"https://openalex.org/I4405256417","display_name":"Institute for Heart Research of the Slovak Academy of Sciences","ror":"https://ror.org/044mjtc47","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210143440","https://openalex.org/I4405256417"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"B Kura","raw_affiliation_strings":["Centre of Experimental Medicine , Institute for Heart Research , Slovak Academy of Sciences , Bratislava , Slovak Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre of Experimental Medicine , Institute for Heart Research , Slovak Academy of Sciences , Bratislava , Slovak Republic","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4210143440","https://openalex.org/I4405256417"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":800,"currency":"EUR","value_usd":862},"apc_paid":{"value":800,"currency":"EUR","value_usd":862},"fwci":0.3891,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.30691824,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"73","issue":"Suppl. 3","first_page":"S671","last_page":"S684"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13775","display_name":"Hydrogen's biological and therapeutic effects","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13775","display_name":"Hydrogen's biological and therapeutic effects","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10736","display_name":"Hydrogen embrittlement and corrosion behaviors in metals","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2506","display_name":"Metals and Alloys"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/molecular-hydrogen","display_name":"molecular hydrogen","score":1.0},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9800000190734863},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.8970000147819519},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.8920000195503235},{"id":"https://openalex.org/keywords/antioxidant-therapy","display_name":"antioxidant therapy","score":0.42500001192092896},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.7860000133514404},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.8579999804496765},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.48500001430511475},{"id":"https://openalex.org/keywords/cognitive-disorders","display_name":"cognitive disorders","score":0.8029999732971191}],"concepts":[{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.8120015859603882},{"id":"https://openalex.org/C111335779","wikidata":"https://www.wikidata.org/wiki/Q3454686","display_name":"Reduction (mathematics)","level":2,"score":0.6176267862319946},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.46194109320640564},{"id":"https://openalex.org/C2991733762","wikidata":"https://www.wikidata.org/wiki/Q82682","display_name":"Oxidation reduction","level":2,"score":0.43378493189811707},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3507961630821228},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3481104075908661},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.25633466243743896},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.18474078178405762},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1639641523361206},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006859","descriptor_name":"Hydrogen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006859","descriptor_name":"Hydrogen","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006859","descriptor_name":"Hydrogen","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.33549/physiolres.935491","doi":"https://doi.org/10.33549/physiolres.935491","is_oa":true,"landing_page_url":"https://doi.org/10.33549/physiolres.935491","pdf_url":"https://doi.org/10.33549/physiolres.935491","source":{"id":"https://openalex.org/S4210199525","display_name":"Physiological Research","issn_l":"0862-8408","issn":["0862-8408","1802-9973"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","medline","norway-1","oarl","poland-40","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310314155","host_organization_name":"Institute of Physiology of the Czech Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310314155","https://openalex.org/P4310314171"],"host_organization_lineage_names":["Institute of Physiology of the Czech Academy of Sciences","Czech Academy of Sciences"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiological Research","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11827053","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11827053","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11827053/pdf/pr73_s671.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiol Res","raw_type":"Text"},{"id":"pmid:39808170","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39808170","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiological research","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.33549/physiolres.935491","doi":"https://doi.org/10.33549/physiolres.935491","is_oa":true,"landing_page_url":"https://doi.org/10.33549/physiolres.935491","pdf_url":"https://doi.org/10.33549/physiolres.935491","source":{"id":"https://openalex.org/S4210199525","display_name":"Physiological Research","issn_l":"0862-8408","issn":["0862-8408","1802-9973"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","medline","norway-1","oarl","poland-40","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310314155","host_organization_name":"Institute of Physiology of the Czech Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310314155","https://openalex.org/P4310314171"],"host_organization_lineage_names":["Institute of Physiology of the Czech Academy of Sciences","Czech Academy of Sciences"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiological Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1079732507","display_name":"Ochrana srdca v situ\u00e1ci\u00e1ch nadmernej tvorby kyslikov\u00fdch a nitrozylov\u00fdch radik\u00e1lov: Molekul\u00e1rny vod\u00edk ako nov\u00fd potenci\u00e1lny therapeutick\u00fd n\u00e1stroj?","funder_award_id":"2/0063/18","funder_id":"https://openalex.org/F4320323641","funder_display_name":"Vedeck\u00e1 Grantov\u00e1 Agent\u00fara M\u0160VVa\u0160 SR a SAV"},{"id":"https://openalex.org/G1211940974","display_name":null,"funder_award_id":"ITMS 26230120009","funder_id":"https://openalex.org/F4320323251","funder_display_name":"Agent\u00fara na Podporu V\u00fdskumu a V\u00fdvoja"},{"id":"https://openalex.org/G1459474918","display_name":null,"funder_award_id":"15-0376","funder_id":"https://openalex.org/F4320323251","funder_display_name":"Agent\u00fara na Podporu V\u00fdskumu a V\u00fdvoja"},{"id":"https://openalex.org/G2231672477","display_name":"\u00daloha miRNA pri vzniku a priebehu kardiovaskul\u00e1rnych ochoren\u00ed - nov\u00e9 pr\u00edstupy ochrany srdca v situ\u00e1ci\u00e1ch zv\u00fd\u0161enej produkcie reakt\u00edvnych foriem kysl\u00edka","funder_award_id":"APVV-19-0317","funder_id":"https://openalex.org/F4320323251","funder_display_name":"Agent\u00fara na Podporu V\u00fdskumu a V\u00fdvoja"},{"id":"https://openalex.org/G2271556247","display_name":"Nekroptotick\u00e9 a pleiotropn\u00e9 \u00fa\u010dinky RIP3 kin\u00e1zy p\u00f4sobiacej ako konvergentn\u00fd bod pri strate srdcov\u00fdch buniek: pochopenie z\u00e1kladn\u00fdch mechanizmov v ischemickom srdci s metabolick\u00fdm stresom alebo bez neho ako n\u00e1stroj n\u00e1vrhu terapeutick\u00fdch pr\u00edstupov.","funder_award_id":"APVV-20-0242","funder_id":"https://openalex.org/F4320323251","funder_display_name":"Agent\u00fara na Podporu V\u00fdskumu a V\u00fdvoja"},{"id":"https://openalex.org/G2541571298","display_name":null,"funder_award_id":"20-0242","funder_id":"https://openalex.org/F4320323251","funder_display_name":"Agent\u00fara na Podporu V\u00fdskumu a V\u00fdvoja"},{"id":"https://openalex.org/G2989169104","display_name":null,"funder_award_id":"2/0063/18","funder_id":"https://openalex.org/F4320323251","funder_display_name":"Agent\u00fara na Podporu V\u00fdskumu a V\u00fdvoja"},{"id":"https://openalex.org/G3628741612","display_name":"\u0160t\u00fadium \u00falohy endog\u00e9nnej kardioprotekcie v myokarde potkana evokovanej nefarmakologick\u00fdmi adapta\u010dn\u00fdmi stimulmi za norm\u00e1lnych a patologick\u00fdch podmienok.","funder_award_id":"2/0104/22","funder_id":"https://openalex.org/F4320323641","funder_display_name":"Vedeck\u00e1 Grantov\u00e1 Agent\u00fara M\u0160VVa\u0160 SR a SAV"},{"id":"https://openalex.org/G3878479425","display_name":null,"funder_award_id":"APVV-19","funder_id":"https://openalex.org/F4320323251","funder_display_name":"Agent\u00fara na Podporu V\u00fdskumu a V\u00fdvoja"},{"id":"https://openalex.org/G4161290220","display_name":null,"funder_award_id":"2018/7838:1-26C0","funder_id":"https://openalex.org/F4320323251","funder_display_name":"Agent\u00fara na Podporu V\u00fdskumu a V\u00fdvoja"},{"id":"https://openalex.org/G4520146804","display_name":null,"funder_award_id":"2018/7838:1-26C0","funder_id":"https://openalex.org/F4320323641","funder_display_name":"Vedeck\u00e1 Grantov\u00e1 Agent\u00fara M\u0160VVa\u0160 SR a SAV"},{"id":"https://openalex.org/G5072035901","display_name":null,"funder_award_id":"2019/4-CEMSAV-1","funder_id":"https://openalex.org/F4320323251","funder_display_name":"Agent\u00fara na Podporu V\u00fdskumu a V\u00fdvoja"},{"id":"https://openalex.org/G582522254","display_name":null,"funder_award_id":"2/0092/22","funder_id":"https://openalex.org/F4320312330","funder_display_name":"Slovensk\u00e1 Akad\u00e9mia Vied"},{"id":"https://openalex.org/G6326497421","display_name":"OCHRANA SRDCA V SITU\u00c1CI\u00c1CH ZV\u00dd\u0160ENEJ PRODUKCIE VO\u013dN\u00ddCH KYSL\u00cdKOV\u00ddCH RADIK\u00c1LOV: RADIA\u010cN\u00c9 A REPERF\u00daZNE PO\u0160KODENIE","funder_award_id":"APVV-15-0376","funder_id":"https://openalex.org/F4320323251","funder_display_name":"Agent\u00fara na Podporu V\u00fdskumu a V\u00fdvoja"},{"id":"https://openalex.org/G6443319733","display_name":"\u00daloha neischemick\u00fdch adapta\u010dn\u00fdch stimulov v ochrane ischemick\u00e9ho myokardu: \u0161t\u00fadium sp\u00fa\u0161\u0165ac\u00edch mechanizmov a bunkovej kardioprotekt\u00edvnej signaliz\u00e1cie","funder_award_id":"APVV-19-0540","funder_id":"https://openalex.org/F4320323251","funder_display_name":"Agent\u00fara na Podporu V\u00fdskumu a V\u00fdvoja"},{"id":"https://openalex.org/G660544542","display_name":null,"funder_award_id":"19-0540","funder_id":"https://openalex.org/F4320323251","funder_display_name":"Agent\u00fara na Podporu V\u00fdskumu a V\u00fdvoja"},{"id":"https://openalex.org/G6612986417","display_name":"Nov\u00e9 met\u00f3dy lie\u010dby srdcov\u00e9ho zlyhania. Prevencia oxida\u010dn\u00e9ho stresu molekul\u00e1rnym vod\u00edkom.","funder_award_id":"2/0092/22","funder_id":"https://openalex.org/F4320323641","funder_display_name":"Vedeck\u00e1 Grantov\u00e1 Agent\u00fara M\u0160VVa\u0160 SR a SAV"},{"id":"https://openalex.org/G6935296250","display_name":null,"funder_award_id":"2/0063/18","funder_id":"https://openalex.org/F4320312330","funder_display_name":"Slovensk\u00e1 Akad\u00e9mia Vied"},{"id":"https://openalex.org/G7373765001","display_name":null,"funder_award_id":"ITMS 26230120009","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G7761450427","display_name":null,"funder_award_id":"APVV-20-","funder_id":"https://openalex.org/F4320323251","funder_display_name":"Agent\u00fara na Podporu V\u00fdskumu a V\u00fdvoja"},{"id":"https://openalex.org/G791075710","display_name":null,"funder_award_id":"APVV-15","funder_id":"https://openalex.org/F4320323251","funder_display_name":"Agent\u00fara na Podporu V\u00fdskumu a V\u00fdvoja"},{"id":"https://openalex.org/G963153051","display_name":null,"funder_award_id":"19-0317","funder_id":"https://openalex.org/F4320323251","funder_display_name":"Agent\u00fara na Podporu V\u00fdskumu a V\u00fdvoja"}],"funders":[{"id":"https://openalex.org/F4320312330","display_name":"Slovensk\u00e1 Akad\u00e9mia Vied","ror":"https://ror.org/03h7qq074"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320323251","display_name":"Agent\u00fara na Podporu V\u00fdskumu a V\u00fdvoja","ror":"https://ror.org/037nx0e70"},{"id":"https://openalex.org/F4320323641","display_name":"Vedeck\u00e1 Grantov\u00e1 Agent\u00fara M\u0160VVa\u0160 SR a SAV","ror":"https://ror.org/044gwpv05"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4406305575.pdf","grobid_xml":"https://content.openalex.org/works/W4406305575.grobid-xml"},"referenced_works_count":55,"referenced_works":["https://openalex.org/W1747806870","https://openalex.org/W1963789809","https://openalex.org/W1968221397","https://openalex.org/W1974539684","https://openalex.org/W1989158389","https://openalex.org/W2010217891","https://openalex.org/W2014789843","https://openalex.org/W2016162629","https://openalex.org/W2033032520","https://openalex.org/W2039898654","https://openalex.org/W2109179624","https://openalex.org/W2111151689","https://openalex.org/W2115708356","https://openalex.org/W2130719735","https://openalex.org/W2142789668","https://openalex.org/W2166276338","https://openalex.org/W2169657429","https://openalex.org/W2230204591","https://openalex.org/W2339478196","https://openalex.org/W2522844221","https://openalex.org/W2602121722","https://openalex.org/W2733994766","https://openalex.org/W2744282338","https://openalex.org/W2747166022","https://openalex.org/W2750885285","https://openalex.org/W2784501904","https://openalex.org/W2803181629","https://openalex.org/W2808010360","https://openalex.org/W2810504199","https://openalex.org/W2903337843","https://openalex.org/W2905168944","https://openalex.org/W2905633918","https://openalex.org/W2905808540","https://openalex.org/W2924100078","https://openalex.org/W2935750259","https://openalex.org/W2947727992","https://openalex.org/W2960761646","https://openalex.org/W2973733841","https://openalex.org/W3012790024","https://openalex.org/W3035541569","https://openalex.org/W3081451680","https://openalex.org/W3111897458","https://openalex.org/W3112352280","https://openalex.org/W4220892878","https://openalex.org/W4233640477","https://openalex.org/W4300198507","https://openalex.org/W4323313762","https://openalex.org/W4366254584","https://openalex.org/W4380680992","https://openalex.org/W4388028993","https://openalex.org/W4391151589","https://openalex.org/W4391892152","https://openalex.org/W4391892210","https://openalex.org/W4393356154","https://openalex.org/W4400723643"],"related_works":["https://openalex.org/W4405505774","https://openalex.org/W2947727992","https://openalex.org/W4414526846","https://openalex.org/W2991527826","https://openalex.org/W3081451680","https://openalex.org/W2109179624","https://openalex.org/W7101161585","https://openalex.org/W4379209695","https://openalex.org/W7216759014","https://openalex.org/W2905168944"],"abstract_inverted_index":{"Disproportion":[0],"between":[1],"reactive":[2],"oxygen":[3],"species":[4],"(ROS)":[5],"production":[6],"and":[7,30,61,65,96],"the":[8,48,54,85],"body's":[9],"antioxidant":[10,50],"system":[11,51],"can":[12,45,70,116],"cause":[13],"oxidative":[14,106],"stress,":[15,136],"which":[16,38,69],"is":[17,109],"considered":[18],"a":[19,100],"common":[20],"denominator":[21],"in":[22,79],"various":[23,74],"pathological":[24],"conditions,":[25],"including":[26],"cardiovascular":[27],"diseases,":[28,138],"aging,":[29],"cognitive":[31],"disorders.":[32],"The":[33],"generation":[34],"of":[35,43,53,102],"free":[36],"radicals,":[37],"occurs":[39],"through":[40],"partial":[41],"reduction":[42],"oxygen,":[44],"quickly":[46],"overwhelm":[47],"endogenous":[49],"capacity":[52],"cell.":[55],"This":[56],"causes":[57],"lipid,":[58],"protein,":[59],"DNA":[60],"RNA":[62],"damage,":[63],"inflammation,":[64],"overall":[66],"cell":[67,131],"degeneration,":[68],"be":[71],"mitigated":[72],"by":[73],"antioxidants.":[75],"However,":[76],"their":[77],"use":[78],"human":[80],"medicine":[81],"did":[82],"not":[83],"bring":[84],"expected":[86],"effect.":[87],"Molecular":[88,139],"hydrogen":[89],"(H2),":[90],"due":[91],"to":[92,111],"its":[93],"unique":[94],"physical":[95],"chemical":[97],"properties,":[98],"provides":[99],"number":[101],"benefits":[103],"for":[104,129],"alleviating":[105],"stress.":[107],"H2":[108],"superior":[110],"conventional":[112],"antioxidants":[113],"as":[114],"it":[115],"selectively":[117],"reduce":[118],"(.)OH":[119],"radicals":[120],"while":[121],"preserving":[122],"important":[123],"ROS":[124],"that":[125],"are":[126],"otherwise":[127],"used":[128],"normal":[130],"signaling.":[132],"Key":[133],"words":[134],"Oxidative":[135],"Cardiovascular":[137],"hydrogen,":[140],"ROS,":[141],"Inflammation.":[142]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2025-01-13T00:00:00"}