{"id":"https://openalex.org/W4406231829","doi":"https://doi.org/10.1038/s41564-024-01895-4","title":"A BCG kill switch strain protects against Mycobacterium tuberculosis in mice and non-human primates with improved safety and immunogenicity","display_name":"A BCG kill switch strain protects against Mycobacterium tuberculosis in mice and non-human primates with improved safety and immunogenicity","publication_year":2025,"publication_date":"2025-01-10","ids":{"openalex":"https://openalex.org/W4406231829","doi":"https://doi.org/10.1038/s41564-024-01895-4","pmid":"https://pubmed.ncbi.nlm.nih.gov/38045242","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10690263"},"language":"en","primary_location":{"id":"doi:10.1038/s41564-024-01895-4","doi":"https://doi.org/10.1038/s41564-024-01895-4","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41564-024-01895-4","pdf_url":null,"source":{"id":"https://openalex.org/S2764926557","display_name":"Nature Microbiology","issn_l":"2058-5276","issn":["2058-5276"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.biorxiv.org/content/biorxiv/early/2023/11/22/2023.11.22.568105.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102088900","display_name":"Alexander A. Smith","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexander A. Smith","raw_affiliation_strings":["Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114187944","display_name":"Hong-Wei Su","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Hongwei Su","raw_affiliation_strings":["Center for Veterinary Science, Zhejiang University, Hangzhou, China","Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Veterinary Science, Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]},{"raw_affiliation_string":"Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Joshua Wallach","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua Wallach","raw_affiliation_strings":["Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100463076","display_name":"Yao Liu","orcid":"https://orcid.org/0000-0002-4330-2389","observed_orcids":["https://orcid.org/0000-0002-4330-2389"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yao Liu","raw_affiliation_strings":["Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0002-4330-2389","affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055778381","display_name":"Pauline A Maiello","orcid":"https://orcid.org/0000-0002-5188-8420","observed_orcids":["https://orcid.org/0000-0002-5188-8420"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pauline Maiello","raw_affiliation_strings":["Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA"],"raw_orcid":"https://orcid.org/0000-0002-5188-8420","affiliations":[{"raw_affiliation_string":"Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028293023","display_name":"Henry Jacob Borish","orcid":"https://orcid.org/0000-0002-9220-673X","observed_orcids":["https://orcid.org/0000-0002-9220-673X"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. Jacob Borish","raw_affiliation_strings":["Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086413795","display_name":"Caylin G. Winchell","orcid":"https://orcid.org/0000-0003-0873-9080","observed_orcids":["https://orcid.org/0000-0003-0873-9080"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Caylin Winchell","raw_affiliation_strings":["Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083185664","display_name":"Andrew W. Simonson","orcid":"https://orcid.org/0000-0003-4789-3873","observed_orcids":["https://orcid.org/0000-0003-4789-3873"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew W. Simonson","raw_affiliation_strings":["Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA"],"raw_orcid":"https://orcid.org/0000-0003-4789-3873","affiliations":[{"raw_affiliation_string":"Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033071848","display_name":"Philana Ling Lin","orcid":"https://orcid.org/0000-0001-5169-3714","observed_orcids":["https://orcid.org/0000-0001-5169-3714"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210130600","display_name":"Children's Hospital of Pittsburgh","ror":"https://ror.org/03763ep67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210134769","display_name":"University of Pittsburgh Medical Center","ror":"https://ror.org/04ehecz88","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210134769"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Philana Ling Lin","raw_affiliation_strings":["Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038214269","display_name":"Mark Rodgers","orcid":"https://orcid.org/0000-0001-9800-3362","observed_orcids":["https://orcid.org/0000-0001-9800-3362","https://orcid.org/0000-0002-5196-9239"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark Rodgers","raw_affiliation_strings":["Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA"],"raw_orcid":"https://orcid.org/0000-0001-9800-3362","affiliations":[{"raw_affiliation_string":"Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007632964","display_name":"Daniel J. Fillmore","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel Fillmore","raw_affiliation_strings":["Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022940277","display_name":"Jennifer Sakal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer Sakal","raw_affiliation_strings":["Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114430035","display_name":"Kan Lin","orcid":"https://orcid.org/0000-0002-5181-4616","observed_orcids":["https://orcid.org/0000-0002-5181-4616"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kan Lin","raw_affiliation_strings":["Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060743530","display_name":"Val\u00e9rie Vinette","orcid":"https://orcid.org/0000-0002-8494-9664","observed_orcids":["https://orcid.org/0000-0002-8494-9664"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Valerie Vinette","raw_affiliation_strings":["Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034087952","display_name":"Dirk Schnappinger","orcid":"https://orcid.org/0000-0002-4445-7219","observed_orcids":["https://orcid.org/0000-0002-4445-7219"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Dirk Schnappinger","raw_affiliation_strings":["Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA. dis2003@med.cornell.edu","Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0002-4445-7219","affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA. dis2003@med.cornell.edu","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023886894","display_name":"Sabine Ehrt","orcid":"https://orcid.org/0000-0002-7951-2310","observed_orcids":["https://orcid.org/0000-0002-7951-2310"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sabine Ehrt","raw_affiliation_strings":["Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA. sae2004@med.cornell.edu","Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0002-7951-2310","affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA. sae2004@med.cornell.edu","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080075194","display_name":"JoAnne L. Flynn","orcid":"https://orcid.org/0000-0001-7874-8981","observed_orcids":["https://orcid.org/0000-0001-7874-8981"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"JoAnne L. Flynn","raw_affiliation_strings":["Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. joanne@pitt.edu","The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. joanne@pitt.edu","Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA"],"raw_orcid":"https://orcid.org/0000-0001-7874-8981","affiliations":[{"raw_affiliation_string":"Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. joanne@pitt.edu","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. joanne@pitt.edu","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"The Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5023886894","https://openalex.org/A5034087952","https://openalex.org/A5080075194"],"corresponding_institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4387153466"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":10.4373,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.98996535,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"10","issue":"2","first_page":"468","last_page":"481"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13410","display_name":"Immune responses and vaccinations","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11381","display_name":"Infectious Diseases and Tuberculosis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mycobacterium-bovis-bcg","display_name":"Mycobacterium bovis BCG","score":0.8870000243186951},{"id":"https://openalex.org/keywords/kill-switch","display_name":"kill switch","score":0.5460000038146973},{"id":"https://openalex.org/keywords/mycobacterium-tuberculosis","display_name":"Mycobacterium tuberculosis","score":0.859000027179718},{"id":"https://openalex.org/keywords/tuberculosis-vaccination","display_name":"tuberculosis vaccination","score":0.8629999756813049},{"id":"https://openalex.org/keywords/tetracycline-inducible-gene-expression","display_name":"tetracycline-inducible expression","score":0.7870000004768372},{"id":"https://openalex.org/keywords/live-attenuated-vaccine","display_name":"live attenuated vaccine","score":0.6259999871253967},{"id":"https://openalex.org/keywords/immunodeficient-mice","display_name":"immunodeficient mice","score":0.7110000252723694},{"id":"https://openalex.org/keywords/macaque","display_name":"macaque","score":0.765999972820282},{"id":"https://openalex.org/keywords/cd4-t-cell-responses","display_name":"CD4+ T cell responses","score":0.7820000052452087},{"id":"https://openalex.org/keywords/vaccine-safety","display_name":"vaccine safety","score":0.7480000257492065},{"id":"https://openalex.org/keywords/sterilizing-immunity","display_name":"sterilizing immunity","score":0.7260000109672546}],"concepts":[{"id":"https://openalex.org/C2780868878","wikidata":"https://www.wikidata.org/wiki/Q1660197","display_name":"Immunogenicity","level":3,"score":0.8083533048629761},{"id":"https://openalex.org/C2778497218","wikidata":"https://www.wikidata.org/wiki/Q133447","display_name":"Mycobacterium bovis","level":4,"score":0.7138630747795105},{"id":"https://openalex.org/C2777975735","wikidata":"https://www.wikidata.org/wiki/Q130971","display_name":"Mycobacterium tuberculosis","level":3,"score":0.6919671297073364},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.606898307800293},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5778464674949646},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.5454961657524109},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.538901686668396},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.5350640416145325},{"id":"https://openalex.org/C2781069245","wikidata":"https://www.wikidata.org/wiki/Q12204","display_name":"Tuberculosis","level":2,"score":0.5090376734733582},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5021796226501465},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4048576056957245},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3003392219543457},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1038/s41564-024-01895-4","doi":"https://doi.org/10.1038/s41564-024-01895-4","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41564-024-01895-4","pdf_url":null,"source":{"id":"https://openalex.org/S2764926557","display_name":"Nature Microbiology","issn_l":"2058-5276","issn":["2058-5276"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Microbiology","raw_type":"journal-article"},{"id":"doi:10.1101/2023.11.22.568105","doi":"https://doi.org/10.1101/2023.11.22.568105","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2023.11.22.568105","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2023/11/22/2023.11.22.568105.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmid:38045242","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38045242","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"bioRxiv : the preprint server for biology","raw_type":"Journal Article"},{"id":"pmid:39794473","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39794473","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature microbiology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12756819","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12756819/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12756819/pdf/nihms-2112085.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nat Microbiol","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:10690263","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10690263","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10690263/pdf/nihpp-2023.11.22.568105v2.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1101/2023.11.22.568105","doi":"https://doi.org/10.1101/2023.11.22.568105","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2023.11.22.568105","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2023/11/22/2023.11.22.568105.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1196564293","display_name":null,"funder_award_id":"R01 AI143788","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G1619536081","display_name":null,"funder_award_id":"AI143788","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G2833012269","display_name":null,"funder_award_id":"75N93019C00071","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2872085235","display_name":null,"funder_award_id":"HHSN2612015000031","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G3917680530","display_name":null,"funder_award_id":"HHSN261201500001C","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4055502225","display_name":"Pittsburgh HIV Mentored Training for Investigation of Co-morbidities and Cure (HIV MeTrICC)","funder_award_id":"K12HL143886","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5358086572","display_name":null,"funder_award_id":"T32AI060525","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G5623900253","display_name":"Development of a Self Inactivating, Highly Effective TB Vaccine","funder_award_id":"R01AI143788","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5936413717","display_name":null,"funder_award_id":"75N93019C00071","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G5944368067","display_name":null,"funder_award_id":"HHSN261201000031C","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G6012682559","display_name":null,"funder_award_id":"HHSN261201500003I","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G6346658092","display_name":null,"funder_award_id":"HHSN2612015000031","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G7578466963","display_name":null,"funder_award_id":"75N93019C00071","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G7977681622","display_name":"Autoimmunity and Immunopathology Training Program","funder_award_id":"T32AI089443","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G8361261777","display_name":null,"funder_award_id":"HHSN261201500001W","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8422249695","display_name":null,"funder_award_id":"HHSN261201500003C","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8796308957","display_name":null,"funder_award_id":"HHSN2612015000031","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8857056862","display_name":null,"funder_award_id":"HHSN261201500001G","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000861211","display_name":"Ghana-SPARCO: Ghana Sickle Pan-African Research Consortium","funder_award_id":"U01HL157004","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000893128","display_name":"Immunology of Infections Disease Renewal 2023","funder_award_id":"T32AI060525","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320306085","display_name":"U.S. Department of Health and Human Services","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320309622","display_name":"Harvard University","ror":"https://ror.org/03vek6s52"},{"id":"https://openalex.org/F4320315952","display_name":"Leidos","ror":"https://ror.org/012cvds63"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4406231829.pdf","grobid_xml":"https://content.openalex.org/works/W4406231829.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W1969822700","https://openalex.org/W1985004048","https://openalex.org/W1995225418","https://openalex.org/W2014375669","https://openalex.org/W2015210486","https://openalex.org/W2016061623","https://openalex.org/W2022980605","https://openalex.org/W2029077665","https://openalex.org/W2034254026","https://openalex.org/W2049261534","https://openalex.org/W2066958748","https://openalex.org/W2101642564","https://openalex.org/W2101706701","https://openalex.org/W2106682613","https://openalex.org/W2109450876","https://openalex.org/W2150600032","https://openalex.org/W2160508951","https://openalex.org/W2285223500","https://openalex.org/W2613567896","https://openalex.org/W2751324502","https://openalex.org/W2760399796","https://openalex.org/W2886578840","https://openalex.org/W2890334235","https://openalex.org/W2900745041","https://openalex.org/W2921585009","https://openalex.org/W2970038586","https://openalex.org/W2983514447","https://openalex.org/W2997968756","https://openalex.org/W3004157864","https://openalex.org/W3043398367","https://openalex.org/W3198857396","https://openalex.org/W4379016235","https://openalex.org/W4387451803"],"related_works":["https://openalex.org/W4388923563","https://openalex.org/W4385687025","https://openalex.org/W2997968756","https://openalex.org/W4396915385","https://openalex.org/W2166376682","https://openalex.org/W7168097887","https://openalex.org/W2034999351","https://openalex.org/W2156704685","https://openalex.org/W2055756355","https://openalex.org/W2518123420"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":2}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2025-01-10T00:00:00"}