{"id":"https://openalex.org/W4406160907","doi":"https://doi.org/10.1016/j.colsurfa.2025.136151","title":"Harnessing Brucea Javanica: Development and characterization of lipid-based niosomes for diabetes treatment","display_name":"Harnessing Brucea Javanica: Development and characterization of lipid-based niosomes for diabetes treatment","publication_year":2025,"publication_date":"2025-01-09","ids":{"openalex":"https://openalex.org/W4406160907","doi":"https://doi.org/10.1016/j.colsurfa.2025.136151"},"language":"en","primary_location":{"id":"doi:10.1016/j.colsurfa.2025.136151","doi":"https://doi.org/10.1016/j.colsurfa.2025.136151","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.colsurfa.2025.136151","pdf_url":null,"source":{"id":"https://openalex.org/S94313546","display_name":"Colloids and Surfaces A Physicochemical and Engineering Aspects","issn_l":"0927-7757","issn":["0927-7757","1873-4359"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Colloids and Surfaces A: Physicochemical and Engineering Aspects","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015011215","display_name":"Husna Zolkepli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Husna Zolkepli","raw_affiliation_strings":["Department of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia","institution_ids":["https://openalex.org/I33849332"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Wen Qi Chia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Wen Qi Chia","raw_affiliation_strings":["Department of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia","institution_ids":["https://openalex.org/I33849332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052165127","display_name":"Rozana Othman","orcid":"https://orcid.org/0000-0002-8260-9252","observed_orcids":["https://orcid.org/0000-0002-8260-9252"]},"institutions":[{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Rozana Othman","raw_affiliation_strings":["Centre for Natural Products Research and Drug Discovery (CENAR), Universiti Malaya, Kuala Lumpur 50603, Malaysia","Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universiti Malaya, Kuala Lumpur 50603, Malaysia"],"raw_orcid":"https://orcid.org/0000-0002-8260-9252","affiliations":[{"raw_affiliation_string":"Centre for Natural Products Research and Drug Discovery (CENAR), Universiti Malaya, Kuala Lumpur 50603, Malaysia","institution_ids":["https://openalex.org/I33849332"]},{"raw_affiliation_string":"Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universiti Malaya, Kuala Lumpur 50603, Malaysia","institution_ids":["https://openalex.org/I33849332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014493357","display_name":"Khalijah Awang","orcid":"https://orcid.org/0000-0001-5971-6570","observed_orcids":["https://orcid.org/0000-0001-5971-6570"]},"institutions":[{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Khalijah Awang","raw_affiliation_strings":["Centre for Natural Products Research and Drug Discovery (CENAR), Universiti Malaya, Kuala Lumpur 50603, Malaysia","Department of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Natural Products Research and Drug Discovery (CENAR), Universiti Malaya, Kuala Lumpur 50603, Malaysia","institution_ids":["https://openalex.org/I33849332"]},{"raw_affiliation_string":"Department of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia","institution_ids":["https://openalex.org/I33849332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075418301","display_name":"Hazrina Hazni","orcid":"https://orcid.org/0000-0002-5980-4869","observed_orcids":["https://orcid.org/0000-0002-5980-4869"]},"institutions":[{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Hazrina Hazni","raw_affiliation_strings":["Centre for Natural Products Research and Drug Discovery (CENAR), Universiti Malaya, Kuala Lumpur 50603, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Natural Products Research and Drug Discovery (CENAR), Universiti Malaya, Kuala Lumpur 50603, Malaysia","institution_ids":["https://openalex.org/I33849332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030280309","display_name":"Syazreen Nadia Sulaiman","orcid":"https://orcid.org/0000-0002-6811-2522","observed_orcids":["https://orcid.org/0000-0002-6811-2522"]},"institutions":[{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Syazreen Nadia Sulaiman","raw_affiliation_strings":["Chemistry Division, Centre for Foundation Studies in Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chemistry Division, Centre for Foundation Studies in Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia","institution_ids":["https://openalex.org/I33849332"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Saidatul Husni Saidin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292896151","display_name":"Forest Research Institute Malaysia","ror":"https://ror.org/01mfdfm52","country_code":"MY","type":"government","lineage":["https://openalex.org/I1292896151","https://openalex.org/I2800327333"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Saidatul Husni Saidin","raw_affiliation_strings":["Natural Products Division, Forest Research Institute Malaysia, Kepong, Selangor 52019, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Natural Products Division, Forest Research Institute Malaysia, Kepong, Selangor 52019, Malaysia","institution_ids":["https://openalex.org/I1292896151"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050466812","display_name":"Manroshan Singh","orcid":"https://orcid.org/0000-0002-8824-6819","observed_orcids":["https://orcid.org/0000-0002-8824-6819"]},"institutions":[{"id":"https://openalex.org/I2799589203","display_name":"Malaysian Rubber Board","ror":"https://ror.org/01h41r361","country_code":"MY","type":"government","lineage":["https://openalex.org/I2799589203"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Manroshan Singh Jaswan Singh","raw_affiliation_strings":["Rubber Research Institute of Malaysia, Malaysian Rubber Board, Sungai Buloh, Selangor 47000, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rubber Research Institute of Malaysia, Malaysian Rubber Board, Sungai Buloh, Selangor 47000, Malaysia","institution_ids":["https://openalex.org/I2799589203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076299529","display_name":"Jonathan Miras","orcid":"https://orcid.org/0000-0001-9286-572X","observed_orcids":["https://orcid.org/0000-0001-9286-572X"]},"institutions":[{"id":"https://openalex.org/I134820265","display_name":"Consejo Superior de Investigaciones Cient\u00edficas","ror":"https://ror.org/02gfc7t72","country_code":"ES","type":"government","lineage":["https://openalex.org/I134820265"]},{"id":"https://openalex.org/I4210105141","display_name":"Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine","ror":"https://ror.org/01gm5f004","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210105141"]},{"id":"https://openalex.org/I4210122902","display_name":"Institute of Advanced Chemistry of Catalonia","ror":"https://ror.org/03srn9y98","country_code":"ES","type":"facility","lineage":["https://openalex.org/I134820265","https://openalex.org/I4210122902"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jonathan Miras","raw_affiliation_strings":["Institute of Advanced Chemistry of Catalonia (IQAC), Consejo Superior de Investigaciones Cient\u00edficas (CSIC) and Networking Research Center on Bioengineering, Biomaterials and Nanomedicine CIBER-BBN), Jordi Girona, 18-26, Barcelona 08034, Spain"],"raw_orcid":"https://orcid.org/0000-0001-9286-572X","affiliations":[{"raw_affiliation_string":"Institute of Advanced Chemistry of Catalonia (IQAC), Consejo Superior de Investigaciones Cient\u00edficas (CSIC) and Networking Research Center on Bioengineering, Biomaterials and Nanomedicine CIBER-BBN), Jordi Girona, 18-26, Barcelona 08034, Spain","institution_ids":["https://openalex.org/I134820265","https://openalex.org/I4210105141","https://openalex.org/I4210122902"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088001978","display_name":"Riyanto Teguh Widodo","orcid":"https://orcid.org/0000-0001-7087-2873","observed_orcids":["https://orcid.org/0000-0001-7087-2873"]},"institutions":[{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]}],"countries":["MY"],"is_corresponding":true,"raw_author_name":"Riyanto Teguh Widodo","raw_affiliation_strings":["Department of Pharmaceutical Technology, Faculty of Pharmacy, Universiti Malaya, Kuala Lumpur 50603, Malaysia"],"raw_orcid":"https://orcid.org/0000-0001-7087-2873","affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Technology, Faculty of Pharmacy, Universiti Malaya, Kuala Lumpur 50603, Malaysia","institution_ids":["https://openalex.org/I33849332"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042931798","display_name":"Noraini Ahmad","orcid":"https://orcid.org/0000-0002-1174-4748","observed_orcids":["https://orcid.org/0000-0002-1174-4748"]},"institutions":[{"id":"https://openalex.org/I33849332","display_name":"University of Malaya","ror":"https://ror.org/00rzspn62","country_code":"MY","type":"education","lineage":["https://openalex.org/I33849332"]}],"countries":["MY"],"is_corresponding":true,"raw_author_name":"Noraini Ahmad","raw_affiliation_strings":["Centre for Natural Products Research and Drug Discovery (CENAR), Universiti Malaya, Kuala Lumpur 50603, Malaysia","Department of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia"],"raw_orcid":"https://orcid.org/0000-0002-1174-4748","affiliations":[{"raw_affiliation_string":"Centre for Natural Products Research and Drug Discovery (CENAR), Universiti Malaya, Kuala Lumpur 50603, Malaysia","institution_ids":["https://openalex.org/I33849332"]},{"raw_affiliation_string":"Department of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia","institution_ids":["https://openalex.org/I33849332"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5042931798","https://openalex.org/A5088001978"],"corresponding_institution_ids":["https://openalex.org/I33849332"],"apc_list":{"value":3200,"currency":"USD","value_usd":3200},"apc_paid":null,"fwci":2.932,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.89440994,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"709","issue":null,"first_page":"136151","last_page":"136151"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":0.3725999891757965,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":0.3725999891757965,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.2506999969482422,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.17499999701976776,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brucea-javanica","display_name":"Brucea javanica","score":0.9929999709129333},{"id":"https://openalex.org/keywords/niosomes","display_name":"niosomes","score":0.9909999966621399},{"id":"https://openalex.org/keywords/lipid-nanocarriers","display_name":"lipid-based nanocarriers","score":0.949999988079071},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9760000109672546},{"id":"https://openalex.org/keywords/plant-extract-encapsulation","display_name":"plant extract encapsulation","score":0.8149999976158142},{"id":"https://openalex.org/keywords/tween-surfactants","display_name":"Tween surfactants","score":0.8080000281333923},{"id":"https://openalex.org/keywords/glycolipids","display_name":"glycolipids","score":0.8339999914169312},{"id":"https://openalex.org/keywords/ethanol-injection","display_name":"ethanol injection","score":0.824999988079071},{"id":"https://openalex.org/keywords/encapsulation-efficiency","display_name":"encapsulation efficiency","score":0.984000027179718},{"id":"https://openalex.org/keywords/sustained-release","display_name":"sustained drug release","score":0.8489999771118164},{"id":"https://openalex.org/keywords/nanocarrier-stability","display_name":"nanocarrier stability","score":0.8180000185966492},{"id":"https://openalex.org/keywords/bioavailability","display_name":"bioavailability","score":0.8939999938011169}],"concepts":[{"id":"https://openalex.org/C72918618","wikidata":"https://www.wikidata.org/wiki/Q1993211","display_name":"Niosome","level":4,"score":0.81537926197052},{"id":"https://openalex.org/C2780841128","wikidata":"https://www.wikidata.org/wiki/Q5073781","display_name":"Characterization (materials science)","level":2,"score":0.6294347643852234},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4967823624610901},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.4416774809360504},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.2518047094345093},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1224508285522461},{"id":"https://openalex.org/C130316041","wikidata":"https://www.wikidata.org/wiki/Q189206","display_name":"Vesicle","level":3,"score":0.12065911293029785},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.0619504451751709}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/j.colsurfa.2025.136151","doi":"https://doi.org/10.1016/j.colsurfa.2025.136151","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.colsurfa.2025.136151","pdf_url":null,"source":{"id":"https://openalex.org/S94313546","display_name":"Colloids and Surfaces A Physicochemical and Engineering Aspects","issn_l":"0927-7757","issn":["0927-7757","1873-4359"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Colloids and Surfaces A: Physicochemical and Engineering Aspects","raw_type":"journal-article"},{"id":"pmh:oai:digital.csic.es:10261/376894","doi":null,"is_oa":false,"landing_page_url":"https://api.elsevier.com/content/abstract/scopus_id/85214574131","pdf_url":null,"source":{"id":"https://openalex.org/S4306400616","display_name":"DIGITAL.CSIC (Spanish National Research Council (CSIC))","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I134820265","host_organization_name":"Consejo Superior de Investigaciones Cient\u00edficas","host_organization_lineage":["https://openalex.org/I134820265"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"http://purl.org/coar/resource_type/c_6501"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322604","display_name":"Universiti Malaya","ror":"https://ror.org/00rzspn62"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1487878063","https://openalex.org/W1973407593","https://openalex.org/W1988144726","https://openalex.org/W2029657155","https://openalex.org/W2082959764","https://openalex.org/W2169271023","https://openalex.org/W2255625473","https://openalex.org/W2314769705","https://openalex.org/W2408788590","https://openalex.org/W2520237808","https://openalex.org/W2571192017","https://openalex.org/W2586194689","https://openalex.org/W2742978833","https://openalex.org/W2889010627","https://openalex.org/W2979111066","https://openalex.org/W3149788606","https://openalex.org/W4200172233","https://openalex.org/W4285041111","https://openalex.org/W4393059240","https://openalex.org/W4394884548"],"related_works":["https://openalex.org/W4399228072","https://openalex.org/W2403149181","https://openalex.org/W4411674973","https://openalex.org/W4410534242","https://openalex.org/W4414199365","https://openalex.org/W7162879148","https://openalex.org/W2593912036","https://openalex.org/W7155522009","https://openalex.org/W4285041111","https://openalex.org/W4413777894"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":6}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2025-01-09T00:00:00"}