{"id":"https://openalex.org/W4406136982","doi":"https://doi.org/10.2196/62851","title":"Artificial Intelligence in Lymphoma Histopathology: Systematic Review","display_name":"Artificial Intelligence in Lymphoma Histopathology: Systematic Review","publication_year":2025,"publication_date":"2025-01-07","ids":{"openalex":"https://openalex.org/W4406136982","doi":"https://doi.org/10.2196/62851","pmid":"https://pubmed.ncbi.nlm.nih.gov/39951716","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11888075"},"language":"en","primary_location":{"id":"doi:10.2196/62851","doi":"https://doi.org/10.2196/62851","is_oa":true,"landing_page_url":"https://doi.org/10.2196/62851","pdf_url":"https://www.jmir.org/2025/1/e62851/PDF","source":{"id":"https://openalex.org/S17147534","display_name":"Journal of Medical Internet Research","issn_l":"1438-8871","issn":["1438-8871","1439-4456"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","fnege-4","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Internet Research","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.jmir.org/2025/1/e62851/PDF","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024339277","display_name":"Yao Fu","orcid":"https://orcid.org/0009-0007-7592-4952","observed_orcids":["https://orcid.org/0009-0007-7592-4952"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yao Fu","raw_affiliation_strings":["Sichuan Tianfu New Area People's Hospital, Chengdu, China"],"raw_orcid":"https://orcid.org/0009-0007-7592-4952","affiliations":[{"raw_affiliation_string":"Sichuan Tianfu New Area People's Hospital, Chengdu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005683806","display_name":"Zongyao Huang","orcid":"https://orcid.org/0000-0001-5474-4118","observed_orcids":["https://orcid.org/0000-0001-5474-4118"]},"institutions":[{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]},{"id":"https://openalex.org/I4210118556","display_name":"Sichuan Cancer Hospital","ror":"https://ror.org/029wq9x81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118556"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zongyao Huang","raw_affiliation_strings":["Department of Pathology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China"],"raw_orcid":"https://orcid.org/0000-0001-5474-4118","affiliations":[{"raw_affiliation_string":"Department of Pathology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China","institution_ids":["https://openalex.org/I150229711","https://openalex.org/I4210118556"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xudong Deng","orcid":"https://orcid.org/0009-0005-5774-4179","observed_orcids":["https://orcid.org/0009-0005-5774-4179"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xudong Deng","raw_affiliation_strings":["Wonders Information Co., Ltd, Shanghai, China"],"raw_orcid":"https://orcid.org/0009-0005-5774-4179","affiliations":[{"raw_affiliation_string":"Wonders Information Co., Ltd, Shanghai, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104778943","display_name":"Linna Xu","orcid":"https://orcid.org/0000-0002-6307-1530","observed_orcids":["https://orcid.org/0000-0002-6307-1530"]},"institutions":[{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]},{"id":"https://openalex.org/I4210118556","display_name":"Sichuan Cancer Hospital","ror":"https://ror.org/029wq9x81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118556"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Linna Xu","raw_affiliation_strings":["Department of Pathology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China"],"raw_orcid":"https://orcid.org/0000-0002-6307-1530","affiliations":[{"raw_affiliation_string":"Department of Pathology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China","institution_ids":["https://openalex.org/I150229711","https://openalex.org/I4210118556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100355946","display_name":"Yang Liu","orcid":"https://orcid.org/0000-0002-6033-0648","observed_orcids":["https://orcid.org/0000-0002-6033-0648"]},"institutions":[{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]},{"id":"https://openalex.org/I4210118556","display_name":"Sichuan Cancer Hospital","ror":"https://ror.org/029wq9x81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118556"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yang Liu","raw_affiliation_strings":["Department of Pathology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China"],"raw_orcid":"https://orcid.org/0000-0002-6033-0648","affiliations":[{"raw_affiliation_string":"Department of Pathology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China","institution_ids":["https://openalex.org/I150229711","https://openalex.org/I4210118556"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Mingxing Zhang","orcid":"https://orcid.org/0009-0001-0013-1428","observed_orcids":["https://orcid.org/0009-0001-0013-1428"]},"institutions":[{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]},{"id":"https://openalex.org/I4210118556","display_name":"Sichuan Cancer Hospital","ror":"https://ror.org/029wq9x81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118556"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mingxing Zhang","raw_affiliation_strings":["Department of Pathology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China"],"raw_orcid":"https://orcid.org/0009-0001-0013-1428","affiliations":[{"raw_affiliation_string":"Department of Pathology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China","institution_ids":["https://openalex.org/I150229711","https://openalex.org/I4210118556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008713529","display_name":"Jinyi Liu","orcid":"https://orcid.org/0009-0002-8349-9304","observed_orcids":["https://orcid.org/0009-0002-8349-9304"]},"institutions":[{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]},{"id":"https://openalex.org/I4210118556","display_name":"Sichuan Cancer Hospital","ror":"https://ror.org/029wq9x81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118556"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jinyi Liu","raw_affiliation_strings":["Phase I Clinical Trial Unit, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China"],"raw_orcid":"https://orcid.org/0009-0002-8349-9304","affiliations":[{"raw_affiliation_string":"Phase I Clinical Trial Unit, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China","institution_ids":["https://openalex.org/I150229711","https://openalex.org/I4210118556"]}]},{"author_position":"last","author":{"id":null,"display_name":"Bin Huang","orcid":"https://orcid.org/0009-0008-6238-1482","observed_orcids":["https://orcid.org/0009-0008-6238-1482"]},"institutions":[{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]},{"id":"https://openalex.org/I4210118556","display_name":"Sichuan Cancer Hospital","ror":"https://ror.org/029wq9x81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118556"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Bin Huang","raw_affiliation_strings":["Department of Pathology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China"],"raw_orcid":"https://orcid.org/0009-0008-6238-1482","affiliations":[{"raw_affiliation_string":"Department of Pathology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China","institution_ids":["https://openalex.org/I150229711","https://openalex.org/I4210118556"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I150229711","https://openalex.org/I4210118556"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":1.6127,"has_fulltext":true,"cited_by_count":29,"citation_normalized_percentile":{"value":0.85309829,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"27","issue":null,"first_page":"e62851","last_page":"e62851"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9702000021934509,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9702000021934509,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.019500000402331352,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.006000000052154064,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"artificial intelligence","score":0.9210000038146973},{"id":"https://openalex.org/keywords/lymphoma","display_name":"lymphoma","score":0.8970000147819519},{"id":"https://openalex.org/keywords/histopathology","display_name":"histopathology","score":0.9580000042915344},{"id":"https://openalex.org/keywords/lymphoma-diagnosis","display_name":"lymphoma diagnosis","score":0.8149999976158142},{"id":"https://openalex.org/keywords/lymphoma-prognosis","display_name":"lymphoma prognosis","score":0.8619999885559082},{"id":"https://openalex.org/keywords/risk-of-bias","display_name":"risk of bias","score":0.8429999947547913},{"id":"https://openalex.org/keywords/probast","display_name":"PROBAST","score":0.6949999928474426},{"id":"https://openalex.org/keywords/diffuse-large-b-cell-lymphoma","display_name":"diffuse large B-cell lymphoma","score":0.7540000081062317},{"id":"https://openalex.org/keywords/follicular-lymphoma","display_name":"follicular lymphoma","score":0.9990000128746033},{"id":"https://openalex.org/keywords/chronic-lymphocytic-leukemia","display_name":"chronic lymphocytic leukemia","score":0.9769999980926514},{"id":"https://openalex.org/keywords/mantle-cell-lymphoma","display_name":"mantle cell lymphoma","score":0.9649999737739563},{"id":"https://openalex.org/keywords/hodgkin-lymphoma","display_name":"Hodgkin's disease","score":0.9739999771118164},{"id":"https://openalex.org/keywords/gene-mutation-prediction","display_name":"gene mutation prediction","score":0.7570000290870667},{"id":"https://openalex.org/keywords/ectopic-expression","display_name":"ectopic expression","score":0.7689999938011169},{"id":"https://openalex.org/keywords/internal-validation","display_name":"internal validation","score":0.6050000190734863},{"id":"https://openalex.org/keywords/clinical-utility","display_name":"clinical utility","score":0.5799999833106995},{"id":"https://openalex.org/keywords/model-interpretability","display_name":"model interpretability","score":0.5580000281333923},{"id":"https://openalex.org/keywords/participant-recruitment","display_name":"participant recruitment","score":0.31200000643730164}],"concepts":[{"id":"https://openalex.org/C43169469","wikidata":"https://www.wikidata.org/wiki/Q580922","display_name":"Preprint","level":2,"score":0.7851279377937317},{"id":"https://openalex.org/C544855455","wikidata":"https://www.wikidata.org/wiki/Q1070952","display_name":"Histopathology","level":2,"score":0.4166320562362671},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3584199547767639},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.34295958280563354},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.28134679794311523},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.22480109333992004}],"mesh":[{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008223","descriptor_name":"Lymphoma","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D008223","descriptor_name":"Lymphoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.2196/62851","doi":"https://doi.org/10.2196/62851","is_oa":true,"landing_page_url":"https://doi.org/10.2196/62851","pdf_url":"https://www.jmir.org/2025/1/e62851/PDF","source":{"id":"https://openalex.org/S17147534","display_name":"Journal of Medical Internet Research","issn_l":"1438-8871","issn":["1438-8871","1439-4456"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","fnege-4","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Internet Research","raw_type":"journal-article"},{"id":"doi:10.2196/preprints.62851","doi":"https://doi.org/10.2196/preprints.62851","is_oa":true,"landing_page_url":"https://doi.org/10.2196/preprints.62851","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},{"id":"pmid:39951716","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39951716","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of medical Internet research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11888075","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11888075/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Med Internet Res","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:1f87bde181f04c8da17299bacdd41b58","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/1f87bde181f04c8da17299bacdd41b58","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Medical Internet Research, Vol 27, p e62851 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.2196/62851","doi":"https://doi.org/10.2196/62851","is_oa":true,"landing_page_url":"https://doi.org/10.2196/62851","pdf_url":"https://www.jmir.org/2025/1/e62851/PDF","source":{"id":"https://openalex.org/S17147534","display_name":"Journal of Medical Internet Research","issn_l":"1438-8871","issn":["1438-8871","1439-4456"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","fnege-4","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Internet Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"}],"awards":[{"id":"https://openalex.org/G6165479841","display_name":null,"funder_award_id":"82300216","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321543","display_name":"China Postdoctoral Science Foundation","ror":"https://ror.org/0426zh255"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4406136982.pdf","grobid_xml":"https://content.openalex.org/works/W4406136982.grobid-xml"},"referenced_works_count":69,"referenced_works":["https://openalex.org/W1594107113","https://openalex.org/W2034770923","https://openalex.org/W2107638293","https://openalex.org/W2310533432","https://openalex.org/W2334884629","https://openalex.org/W2470965540","https://openalex.org/W2761290139","https://openalex.org/W2807104763","https://openalex.org/W2809275911","https://openalex.org/W2894917609","https://openalex.org/W2897434820","https://openalex.org/W2907554860","https://openalex.org/W2938746851","https://openalex.org/W2945976633","https://openalex.org/W2972354804","https://openalex.org/W2997524881","https://openalex.org/W3012124463","https://openalex.org/W3018295606","https://openalex.org/W3021413349","https://openalex.org/W3032044812","https://openalex.org/W3035051874","https://openalex.org/W3037740841","https://openalex.org/W3082487208","https://openalex.org/W3086629307","https://openalex.org/W3088167459","https://openalex.org/W3109772564","https://openalex.org/W3132478226","https://openalex.org/W3134718139","https://openalex.org/W3143826885","https://openalex.org/W3144729742","https://openalex.org/W3158221061","https://openalex.org/W3162236650","https://openalex.org/W3164774700","https://openalex.org/W3198195620","https://openalex.org/W3200077256","https://openalex.org/W3209729653","https://openalex.org/W3210004797","https://openalex.org/W3211235220","https://openalex.org/W4211229712","https://openalex.org/W4220652578","https://openalex.org/W4224931725","https://openalex.org/W4246888238","https://openalex.org/W4280555363","https://openalex.org/W4280614119","https://openalex.org/W4295592080","https://openalex.org/W4296777402","https://openalex.org/W4296964708","https://openalex.org/W4309162340","https://openalex.org/W4311053258","https://openalex.org/W4312018365","https://openalex.org/W4312195463","https://openalex.org/W4313478927","https://openalex.org/W4367297900","https://openalex.org/W4375953538","https://openalex.org/W4379094598","https://openalex.org/W4379231567","https://openalex.org/W4383104788","https://openalex.org/W4385618953","https://openalex.org/W4385751426","https://openalex.org/W4386100239","https://openalex.org/W4388105950","https://openalex.org/W4391027739","https://openalex.org/W4391875518","https://openalex.org/W4393224994","https://openalex.org/W4393388476","https://openalex.org/W4394572135","https://openalex.org/W4394894573","https://openalex.org/W4396612818","https://openalex.org/W4396637260"],"related_works":["https://openalex.org/W7136335564","https://openalex.org/W4390662926","https://openalex.org/W7117355213","https://openalex.org/W4416787219","https://openalex.org/W4386327995","https://openalex.org/W7160776374","https://openalex.org/W7171683246","https://openalex.org/W4388638145","https://openalex.org/W4388541018","https://openalex.org/W4404488049"],"abstract_inverted_index":{"BACKGROUND:":[0],"Artificial":[1],"intelligence":[2],"(AI)":[3],"shows":[4],"considerable":[5],"promise":[6],"in":[7,189,254,287,315,444],"the":[8,25,40,53,69,99,123,154,178,190,246,260,291,294,316,319,337,344,347,371,390,396,409,415,419,422,429,445],"areas":[9],"of":[10,21,28,42,56,86,101,118,127,183,221,231,252,279,285,341,389,392,398,412,417,426,431,447],"lymphoma":[11,49,107,298],"diagnosis,":[12,111],"prognosis,":[13],"and":[14,24,51,84,140,152,162,206,228,267,282,310,333,358,395,424,433,436,441],"gene":[15,112,204],"prediction.":[16],"However,":[17],"a":[18,216,283,380],"comprehensive":[19,57,75,410],"assessment":[20],"potential":[22],"biases":[23,41],"clinical":[26,54,400],"utility":[27,55],"AI":[29,46,58,102,135,185,393,427],"models":[30,47,59,186,200,209,236,366,384,394],"is":[31,147],"still":[32],"needed.":[33],"OBJECTIVE:":[34],"Our":[35],"goal":[36],"was":[37,78,120,137],"to":[38,68,211,225,242,356,363,376,438],"evaluate":[39],"published":[43],"studies":[44,214],"using":[45,122],"for":[48,60,103,133,159,201,274],"histopathology":[50],"assess":[52],"diagnosis":[61],"or":[62,218],"prognosis.":[63],"METHODS:":[64],"This":[65],"study":[66,146,420],"adhered":[67],"Systematic":[70,160],"Review":[71],"Reporting":[72,157],"Standards.":[73],"A":[74,181],"literature":[76],"search":[77,96,169],"conducted":[79],"across":[80],"PubMed,":[81],"Cochrane":[82],"Library,":[83],"Web":[85],"Science":[87],"from":[88,354,361,374],"their":[89,399],"inception":[90],"until":[91],"August":[92],"30,":[93],"2024.":[94],"The":[95,116,145,168,271,387],"criteria":[97],"included":[98,188],"use":[100,430],"prognosis":[104],"involving":[105],"human":[106],"tissue":[108],"pathology":[109],"images,":[110],"mutation":[113],"prediction,":[114],"etc.":[115],"risk":[117,220,251],"bias":[119,253],"evaluated":[121],"Prediction":[124],"Model":[125],"Risk":[126],"Bias":[128],"Assessment":[129],"Tool":[130],"(PROBAST).":[131],"Information":[132],"each":[134],"model":[136],"systematically":[138],"tabulated,":[139],"summary":[141],"statistics":[142],"were":[143,187,276,300,323],"reported.":[144],"registered":[148],"with":[149,173,259,367],"PROSPERO":[150],"(CRD42024537394)":[151],"follows":[153],"PRISMA":[155],"(Preferred":[156],"Items":[158],"Reviews":[161],"Meta-Analyses)":[163],"2020":[164],"reporting":[165,230,411],"guidelines.":[166],"RESULTS:":[167],"identified":[170],"3565":[171],"records,":[172],"41":[174,184],"articles":[175,247],"ultimately":[176],"meeting":[177],"inclusion":[179],"criteria.":[180],"total":[182],"analysis,":[191],"comprising":[192],"17":[193],"diagnostic":[194,292],"models,":[195,198,293,318,343,428],"10":[196],"prognostic":[197,317],"2":[199],"detecting":[202],"ectopic":[203],"expression,":[205],"12":[207],"additional":[208],"related":[210],"diagnosis.":[212],"All":[213],"exhibited":[215,385],"high":[217],"unclear":[219,250],"bias,":[222],"primarily":[223],"due":[224],"limited":[226],"analysis":[227,269,278],"incomplete":[229],"participant":[232,264,280],"recruitment.":[233],"Most":[234],"high-risk":[235,240],"(10/41)":[237],"predominantly":[238],"assigned":[239],"classifications":[241],"participants.":[243],"Almost":[244],"all":[245,342,383],"presented":[248],"an":[249],"at":[255],"least":[256],"one":[257],"domain,":[258],"most":[261,295,320],"frequent":[262],"being":[263],"selection":[265],"(16/41)":[266],"statistical":[268],"(37/41).":[270],"primary":[272],"reasons":[273],"this":[275],"insufficient":[277],"recruitment":[281],"lack":[284],"interpretability":[286,425],"outcome":[288],"analyses.":[289],"In":[290,336,365],"frequently":[296],"studied":[297],"subtypes":[299,322],"diffuse":[301,324],"large":[302,325],"B-cell":[303,326],"lymphoma,":[304,306,313,327,329],"follicular":[305,328],"chronic":[307,330],"lymphocytic":[308,331],"leukemia,":[309,332],"mantle":[311],"cell":[312],"while":[314],"common":[321],"Hodgkin":[334],"lymphoma.":[335],"internal":[338],"validation":[339,369],"results":[340],"area":[345],"under":[346],"receiver":[348],"operating":[349],"characteristic":[350],"curve":[351],"(AUC)":[352],"ranged":[353,360,373],"0.75":[355],"0.99":[357],"accuracy":[359,391],"68.3%":[362],"100%.":[364],"external":[368,434],"results,":[370],"AUC":[372],"0.93":[375],"0.99.":[377],"CONCLUSIONS:":[378],"From":[379],"methodological":[381],"perspective,":[382],"biases.":[386],"enhancement":[388],"acceleration":[397],"translation":[401],"hinge":[402],"on":[403],"several":[404],"critical":[405],"aspects.":[406],"These":[407],"include":[408],"data":[413],"sources,":[414],"diversity":[416],"datasets,":[418],"design,":[421],"transparency":[423],"cross-validation":[432],"validation,":[435],"adherence":[437],"regulatory":[439],"guidance":[440],"standardized":[442],"processes":[443],"field":[446],"medical":[448],"AI.":[449]},"counts_by_year":[{"year":2026,"cited_by_count":20},{"year":2025,"cited_by_count":9}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2025-01-08T00:00:00"}