{"id":"https://openalex.org/W4406135884","doi":"https://doi.org/10.1098/rsob.240310","title":"Structure of WzxE the lipid III flippase for Enterobacterial Common Antigen polysaccharide","display_name":"Structure of WzxE the lipid III flippase for Enterobacterial Common Antigen polysaccharide","publication_year":2025,"publication_date":"2025-01-01","ids":{"openalex":"https://openalex.org/W4406135884","doi":"https://doi.org/10.1098/rsob.240310","pmid":"https://pubmed.ncbi.nlm.nih.gov/39772807","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11706664"},"language":"en","primary_location":{"id":"doi:10.1098/rsob.240310","doi":"https://doi.org/10.1098/rsob.240310","is_oa":true,"landing_page_url":"https://doi.org/10.1098/rsob.240310","pdf_url":null,"source":{"id":"https://openalex.org/S80033963","display_name":"Open Biology","issn_l":"2046-2441","issn":["2046-2441"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319787","host_organization_name":"Royal Society","host_organization_lineage":["https://openalex.org/P4310319787"],"host_organization_lineage_names":["Royal Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1098/rsob.240310","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068053923","display_name":"Audrey Le Bas","orcid":"https://orcid.org/0000-0002-1100-6833","observed_orcids":["https://orcid.org/0000-0002-1100-6833"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210103985","display_name":"Rosalind Franklin Institute","ror":"https://ror.org/01djcs087","country_code":"GB","type":"education","lineage":["https://openalex.org/I4210103985"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Audrey Le Bas","raw_affiliation_strings":["Division of Structural Biology, University of Oxford, Roosevelt Drive","Rosalind Franklin Institute, Harwell Campus","Rosalind Franklin Institute, Harwell Campus, Didcot, UK"],"raw_orcid":"https://orcid.org/0000-0002-1100-6833","affiliations":[{"raw_affiliation_string":"Division of Structural Biology, University of Oxford, Roosevelt Drive","institution_ids":["https://openalex.org/I40120149"]},{"raw_affiliation_string":"Rosalind Franklin Institute, Harwell Campus","institution_ids":["https://openalex.org/I4210103985"]},{"raw_affiliation_string":"Rosalind Franklin Institute, Harwell Campus, Didcot, UK","institution_ids":["https://openalex.org/I4210103985"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081981573","display_name":"Bradley R. Clarke","orcid":"https://orcid.org/0000-0003-2233-1268","observed_orcids":["https://orcid.org/0000-0003-2233-1268"]},"institutions":[{"id":"https://openalex.org/I79817857","display_name":"University of Guelph","ror":"https://ror.org/01r7awg59","country_code":"CA","type":"education","lineage":["https://openalex.org/I79817857"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Bradley R. Clarke","raw_affiliation_strings":["Department of Molecular and Cellular Biology, University of Guelph","Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cellular Biology, University of Guelph","institution_ids":["https://openalex.org/I79817857"]},{"raw_affiliation_string":"Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada","institution_ids":["https://openalex.org/I79817857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066167179","display_name":"Tanisha Teelucksingh","orcid":"https://orcid.org/0000-0002-1151-8433","observed_orcids":["https://orcid.org/0000-0002-1151-8433"]},"institutions":[{"id":"https://openalex.org/I79817857","display_name":"University of Guelph","ror":"https://ror.org/01r7awg59","country_code":"CA","type":"education","lineage":["https://openalex.org/I79817857"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Tanisha Teelucksingh","raw_affiliation_strings":["Department of Molecular and Cellular Biology, University of Guelph","Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cellular Biology, University of Guelph","institution_ids":["https://openalex.org/I79817857"]},{"raw_affiliation_string":"Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada","institution_ids":["https://openalex.org/I79817857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040591109","display_name":"Micah Lee","orcid":"https://orcid.org/0000-0001-8447-0314","observed_orcids":["https://orcid.org/0000-0001-8447-0314"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Micah Lee","raw_affiliation_strings":["Division of Structural Biology, University of Oxford, Roosevelt Drive","Division of Structural Biology, University of Oxford, Roosevelt Drive, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Structural Biology, University of Oxford, Roosevelt Drive","institution_ids":["https://openalex.org/I40120149"]},{"raw_affiliation_string":"Division of Structural Biology, University of Oxford, Roosevelt Drive, Oxford, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030676931","display_name":"Kamel El Omari","orcid":"https://orcid.org/0000-0003-3506-6045","observed_orcids":["https://orcid.org/0000-0003-3506-6045"]},"institutions":[{"id":"https://openalex.org/I2802711169","display_name":"Diamond Light Source","ror":"https://ror.org/05etxs293","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2802711169"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kamel El Omari","raw_affiliation_strings":["Diamond Light Source, Harwell Science and Innovation Campus","Diamond Light Source, Harwell Science and Innovation Campus, Didcot, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diamond Light Source, Harwell Science and Innovation Campus","institution_ids":["https://openalex.org/I2802711169"]},{"raw_affiliation_string":"Diamond Light Source, Harwell Science and Innovation Campus, Didcot, UK","institution_ids":["https://openalex.org/I2802711169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034140391","display_name":"Andrew M. Giltrap","orcid":"https://orcid.org/0000-0001-8960-553X","observed_orcids":["https://orcid.org/0000-0001-8960-553X"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210103985","display_name":"Rosalind Franklin Institute","ror":"https://ror.org/01djcs087","country_code":"GB","type":"education","lineage":["https://openalex.org/I4210103985"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew M. Giltrap","raw_affiliation_strings":["Department of Chemistry, Chemistry Research Laboratory, University of Oxford","Department of Pharmacology, University of Oxford","Rosalind Franklin Institute, Harwell Campus","Rosalind Franklin Institute, Harwell Campus, Didcot, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Chemistry Research Laboratory, University of Oxford","institution_ids":["https://openalex.org/I40120149"]},{"raw_affiliation_string":"Department of Pharmacology, University of Oxford","institution_ids":["https://openalex.org/I40120149"]},{"raw_affiliation_string":"Rosalind Franklin Institute, Harwell Campus","institution_ids":["https://openalex.org/I4210103985"]},{"raw_affiliation_string":"Rosalind Franklin Institute, Harwell Campus, Didcot, UK","institution_ids":["https://openalex.org/I4210103985"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047508911","display_name":"Stephen A. McMahon","orcid":"https://orcid.org/0000-0003-4273-8364","observed_orcids":["https://orcid.org/0000-0003-4273-8364"]},"institutions":[{"id":"https://openalex.org/I16835326","display_name":"University of St Andrews","ror":"https://ror.org/02wn5qz54","country_code":"GB","type":"education","lineage":["https://openalex.org/I16835326"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stephen A. McMahon","raw_affiliation_strings":["Biomedical Sciences Research Complex, North Haugh, University of St Andrews","Biomedical Sciences Research Complex, North Haugh, University of St Andrews, St Andrews, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Sciences Research Complex, North Haugh, University of St Andrews","institution_ids":["https://openalex.org/I16835326"]},{"raw_affiliation_string":"Biomedical Sciences Research Complex, North Haugh, University of St Andrews, St Andrews, UK","institution_ids":["https://openalex.org/I16835326"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102011899","display_name":"Hui Liu","orcid":"https://orcid.org/0009-0009-4988-9561","observed_orcids":["https://orcid.org/0009-0009-4988-9561"]},"institutions":[{"id":"https://openalex.org/I16835326","display_name":"University of St Andrews","ror":"https://ror.org/02wn5qz54","country_code":"GB","type":"education","lineage":["https://openalex.org/I16835326"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Hui Liu","raw_affiliation_strings":["Biomedical Sciences Research Complex, North Haugh, University of St Andrews","Biomedical Sciences Research Complex, North Haugh, University of St Andrews, St Andrews, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Sciences Research Complex, North Haugh, University of St Andrews","institution_ids":["https://openalex.org/I16835326"]},{"raw_affiliation_string":"Biomedical Sciences Research Complex, North Haugh, University of St Andrews, St Andrews, UK","institution_ids":["https://openalex.org/I16835326"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082840498","display_name":"John H. Beale","orcid":"https://orcid.org/0000-0003-1171-2428","observed_orcids":["https://orcid.org/0000-0003-1171-2428"]},"institutions":[{"id":"https://openalex.org/I2802711169","display_name":"Diamond Light Source","ror":"https://ror.org/05etxs293","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2802711169"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"John H. Beale","raw_affiliation_strings":["Diamond Light Source, Harwell Science and Innovation Campus","Diamond Light Source, Harwell Science and Innovation Campus, Didcot, UK"],"raw_orcid":"https://orcid.org/0000-0003-1171-2428","affiliations":[{"raw_affiliation_string":"Diamond Light Source, Harwell Science and Innovation Campus","institution_ids":["https://openalex.org/I2802711169"]},{"raw_affiliation_string":"Diamond Light Source, Harwell Science and Innovation Campus, Didcot, UK","institution_ids":["https://openalex.org/I2802711169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110651859","display_name":"Vitaliy B. Mykhaylyk","orcid":"https://orcid.org/0000-0003-0106-2724","observed_orcids":["https://orcid.org/0000-0003-0106-2724"]},"institutions":[{"id":"https://openalex.org/I2802711169","display_name":"Diamond Light Source","ror":"https://ror.org/05etxs293","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2802711169"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Vitaliy Mykhaylyk","raw_affiliation_strings":["Diamond Light Source, Harwell Science and Innovation Campus","Diamond Light Source, Harwell Science and Innovation Campus, Didcot, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diamond Light Source, Harwell Science and Innovation Campus","institution_ids":["https://openalex.org/I2802711169"]},{"raw_affiliation_string":"Diamond Light Source, Harwell Science and Innovation Campus, Didcot, UK","institution_ids":["https://openalex.org/I2802711169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088938706","display_name":"Ramona Duman","orcid":"https://orcid.org/0000-0002-3566-8698","observed_orcids":["https://orcid.org/0000-0002-3566-8698"]},"institutions":[{"id":"https://openalex.org/I2802711169","display_name":"Diamond Light Source","ror":"https://ror.org/05etxs293","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2802711169"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ramona Duman","raw_affiliation_strings":["Diamond Light Source, Harwell Science and Innovation Campus","Diamond Light Source, Harwell Science and Innovation Campus, Didcot, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diamond Light Source, Harwell Science and Innovation Campus","institution_ids":["https://openalex.org/I2802711169"]},{"raw_affiliation_string":"Diamond Light Source, Harwell Science and Innovation Campus, Didcot, UK","institution_ids":["https://openalex.org/I2802711169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009305938","display_name":"Neil G. Paterson","orcid":"https://orcid.org/0000-0003-4292-6971","observed_orcids":["https://orcid.org/0000-0003-4292-6971"]},"institutions":[{"id":"https://openalex.org/I2802711169","display_name":"Diamond Light Source","ror":"https://ror.org/05etxs293","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2802711169"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Neil G. Paterson","raw_affiliation_strings":["Diamond Light Source, Harwell Science and Innovation Campus","Diamond Light Source, Harwell Science and Innovation Campus, Didcot, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diamond Light Source, Harwell Science and Innovation Campus","institution_ids":["https://openalex.org/I2802711169"]},{"raw_affiliation_string":"Diamond Light Source, Harwell Science and Innovation Campus, Didcot, UK","institution_ids":["https://openalex.org/I2802711169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069167048","display_name":"Philip N. Ward","orcid":"https://orcid.org/0000-0003-2546-3426","observed_orcids":["https://orcid.org/0000-0003-2546-3426"]},"institutions":[{"id":"https://openalex.org/I4210103985","display_name":"Rosalind Franklin Institute","ror":"https://ror.org/01djcs087","country_code":"GB","type":"education","lineage":["https://openalex.org/I4210103985"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Philip N. Ward","raw_affiliation_strings":["Rosalind Franklin Institute, Harwell Campus","Rosalind Franklin Institute, Harwell Campus, Didcot, UK"],"raw_orcid":"https://orcid.org/0000-0003-2546-3426","affiliations":[{"raw_affiliation_string":"Rosalind Franklin Institute, Harwell Campus","institution_ids":["https://openalex.org/I4210103985"]},{"raw_affiliation_string":"Rosalind Franklin Institute, Harwell Campus, Didcot, UK","institution_ids":["https://openalex.org/I4210103985"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002644042","display_name":"Peter J. Harrison","orcid":"https://orcid.org/0000-0001-5167-0547","observed_orcids":["https://orcid.org/0000-0001-5167-0547"]},"institutions":[{"id":"https://openalex.org/I2802711169","display_name":"Diamond Light Source","ror":"https://ror.org/05etxs293","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2802711169"]},{"id":"https://openalex.org/I4210092957","display_name":"Research Complex at Harwell","ror":"https://ror.org/00gqx0331","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210092957"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Peter J. Harrison","raw_affiliation_strings":["Membrane Protein Laboratory, Diamond Light Source, Research Complex at Harwell","Membrane Protein Laboratory, Diamond Light Source, Research Complex at Harwell, Didcot, UK"],"raw_orcid":"https://orcid.org/0000-0001-5167-0547","affiliations":[{"raw_affiliation_string":"Membrane Protein Laboratory, Diamond Light Source, Research Complex at Harwell","institution_ids":["https://openalex.org/I2802711169","https://openalex.org/I4210092957"]},{"raw_affiliation_string":"Membrane Protein Laboratory, Diamond Light Source, Research Complex at Harwell, Didcot, UK","institution_ids":["https://openalex.org/I2802711169","https://openalex.org/I4210092957"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018022775","display_name":"Miriam Weckener","orcid":"https://orcid.org/0000-0002-1419-9378","observed_orcids":["https://orcid.org/0000-0002-1419-9378"]},"institutions":[{"id":"https://openalex.org/I4210103985","display_name":"Rosalind Franklin Institute","ror":"https://ror.org/01djcs087","country_code":"GB","type":"education","lineage":["https://openalex.org/I4210103985"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Miriam Weckener","raw_affiliation_strings":["Rosalind Franklin Institute, Harwell Campus","Rosalind Franklin Institute, Harwell Campus, Didcot, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rosalind Franklin Institute, Harwell Campus","institution_ids":["https://openalex.org/I4210103985"]},{"raw_affiliation_string":"Rosalind Franklin Institute, Harwell Campus, Didcot, UK","institution_ids":["https://openalex.org/I4210103985"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002431875","display_name":"Els Pardon","orcid":"https://orcid.org/0000-0002-2466-0172","observed_orcids":["https://orcid.org/0000-0002-2466-0172"]},"institutions":[{"id":"https://openalex.org/I13469542","display_name":"Vrije Universiteit Brussel","ror":"https://ror.org/006e5kg04","country_code":"BE","type":"education","lineage":["https://openalex.org/I13469542"]},{"id":"https://openalex.org/I4210140355","display_name":"VIB-VUB Center for Structural Biology","ror":"https://ror.org/03e84cm85","country_code":"BE","type":"facility","lineage":["https://openalex.org/I13469542","https://openalex.org/I2802017950","https://openalex.org/I4210140355"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Els Pardon","raw_affiliation_strings":["Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Pleinlaan 2, Brussels B-1050, Belgium","VIB-VUB Center for Structural Biology, VIB, Pleinlaan 2, Brussels B-1050, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Pleinlaan 2, Brussels B-1050, Belgium","institution_ids":["https://openalex.org/I13469542"]},{"raw_affiliation_string":"VIB-VUB Center for Structural Biology, VIB, Pleinlaan 2, Brussels B-1050, Belgium","institution_ids":["https://openalex.org/I4210140355"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001394494","display_name":"Jan Steyaert","orcid":"https://orcid.org/0000-0002-3825-874X","observed_orcids":["https://orcid.org/0000-0002-3825-874X"]},"institutions":[{"id":"https://openalex.org/I13469542","display_name":"Vrije Universiteit Brussel","ror":"https://ror.org/006e5kg04","country_code":"BE","type":"education","lineage":["https://openalex.org/I13469542"]},{"id":"https://openalex.org/I4210140355","display_name":"VIB-VUB Center for Structural Biology","ror":"https://ror.org/03e84cm85","country_code":"BE","type":"facility","lineage":["https://openalex.org/I13469542","https://openalex.org/I2802017950","https://openalex.org/I4210140355"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Jan Steyaert","raw_affiliation_strings":["Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Pleinlaan 2, Brussels B-1050, Belgium","VIB-VUB Center for Structural Biology, VIB, Pleinlaan 2, Brussels B-1050, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Pleinlaan 2, Brussels B-1050, Belgium","institution_ids":["https://openalex.org/I13469542"]},{"raw_affiliation_string":"VIB-VUB Center for Structural Biology, VIB, Pleinlaan 2, Brussels B-1050, Belgium","institution_ids":["https://openalex.org/I4210140355"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060396046","display_name":"Huanting Liu","orcid":"https://orcid.org/0000-0001-5953-9367","observed_orcids":["https://orcid.org/0000-0001-5953-9367"]},"institutions":[{"id":"https://openalex.org/I16835326","display_name":"University of St Andrews","ror":"https://ror.org/02wn5qz54","country_code":"GB","type":"education","lineage":["https://openalex.org/I16835326"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Huanting Liu","raw_affiliation_strings":["Biomedical Sciences Research Complex, North Haugh, University of St Andrews","Biomedical Sciences Research Complex, North Haugh, University of St Andrews, St Andrews, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Sciences Research Complex, North Haugh, University of St Andrews","institution_ids":["https://openalex.org/I16835326"]},{"raw_affiliation_string":"Biomedical Sciences Research Complex, North Haugh, University of St Andrews, St Andrews, UK","institution_ids":["https://openalex.org/I16835326"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069686330","display_name":"Andrew Quigley","orcid":"https://orcid.org/0000-0002-5022-9845","observed_orcids":["https://orcid.org/0000-0002-5022-9845"]},"institutions":[{"id":"https://openalex.org/I2802711169","display_name":"Diamond Light Source","ror":"https://ror.org/05etxs293","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2802711169"]},{"id":"https://openalex.org/I4210092957","display_name":"Research Complex at Harwell","ror":"https://ror.org/00gqx0331","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210092957"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew Quigley","raw_affiliation_strings":["Membrane Protein Laboratory, Diamond Light Source, Research Complex at Harwell","Membrane Protein Laboratory, Diamond Light Source, Research Complex at Harwell, Didcot, UK"],"raw_orcid":"https://orcid.org/0000-0002-5022-9845","affiliations":[{"raw_affiliation_string":"Membrane Protein Laboratory, Diamond Light Source, Research Complex at Harwell","institution_ids":["https://openalex.org/I2802711169","https://openalex.org/I4210092957"]},{"raw_affiliation_string":"Membrane Protein Laboratory, Diamond Light Source, Research Complex at Harwell, Didcot, UK","institution_ids":["https://openalex.org/I2802711169","https://openalex.org/I4210092957"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043732814","display_name":"Benjamin G. Davis","orcid":"https://orcid.org/0000-0002-5056-407X","observed_orcids":["https://orcid.org/0000-0002-5056-407X"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210103985","display_name":"Rosalind Franklin Institute","ror":"https://ror.org/01djcs087","country_code":"GB","type":"education","lineage":["https://openalex.org/I4210103985"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Benjamin G. Davis","raw_affiliation_strings":["Department of Chemistry, Chemistry Research Laboratory, University of Oxford","Department of Pharmacology, University of Oxford","Rosalind Franklin Institute, Harwell Campus","Rosalind Franklin Institute, Harwell Campus, Didcot, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Chemistry Research Laboratory, University of Oxford","institution_ids":["https://openalex.org/I40120149"]},{"raw_affiliation_string":"Department of Pharmacology, University of Oxford","institution_ids":["https://openalex.org/I40120149"]},{"raw_affiliation_string":"Rosalind Franklin Institute, Harwell Campus","institution_ids":["https://openalex.org/I4210103985"]},{"raw_affiliation_string":"Rosalind Franklin Institute, Harwell Campus, Didcot, UK","institution_ids":["https://openalex.org/I4210103985"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066825213","display_name":"Armin Wagner","orcid":"https://orcid.org/0000-0001-8995-7324","observed_orcids":["https://orcid.org/0000-0001-8995-7324"]},"institutions":[{"id":"https://openalex.org/I2802711169","display_name":"Diamond Light Source","ror":"https://ror.org/05etxs293","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2802711169"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Armin Wagner","raw_affiliation_strings":["Diamond Light Source, Harwell Science and Innovation Campus","Diamond Light Source, Harwell Science and Innovation Campus, Didcot, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diamond Light Source, Harwell Science and Innovation Campus","institution_ids":["https://openalex.org/I2802711169"]},{"raw_affiliation_string":"Diamond Light Source, Harwell Science and Innovation Campus, Didcot, UK","institution_ids":["https://openalex.org/I2802711169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062469858","display_name":"Chris Whitfield","orcid":"https://orcid.org/0000-0002-5267-7027","observed_orcids":["https://orcid.org/0000-0002-5267-7027"]},"institutions":[{"id":"https://openalex.org/I79817857","display_name":"University of Guelph","ror":"https://ror.org/01r7awg59","country_code":"CA","type":"education","lineage":["https://openalex.org/I79817857"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Chris Whitfield","raw_affiliation_strings":["Department of Molecular and Cellular Biology, University of Guelph","Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cellular Biology, University of Guelph","institution_ids":["https://openalex.org/I79817857"]},{"raw_affiliation_string":"Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada","institution_ids":["https://openalex.org/I79817857"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066756448","display_name":"James H. Naismith","orcid":"https://orcid.org/0000-0001-6744-5061","observed_orcids":["https://orcid.org/0000-0001-6744-5061"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210103985","display_name":"Rosalind Franklin Institute","ror":"https://ror.org/01djcs087","country_code":"GB","type":"education","lineage":["https://openalex.org/I4210103985"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"James H. Naismith","raw_affiliation_strings":["Division of Structural Biology, University of Oxford, Roosevelt Drive","Rosalind Franklin Institute, Harwell Campus","Rosalind Franklin Institute, Harwell Campus, Didcot, UK"],"raw_orcid":"https://orcid.org/0000-0001-6744-5061","affiliations":[{"raw_affiliation_string":"Division of Structural Biology, University of Oxford, Roosevelt Drive","institution_ids":["https://openalex.org/I40120149"]},{"raw_affiliation_string":"Rosalind Franklin Institute, Harwell Campus","institution_ids":["https://openalex.org/I4210103985"]},{"raw_affiliation_string":"Rosalind Franklin Institute, Harwell Campus, Didcot, UK","institution_ids":["https://openalex.org/I4210103985"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5062469858","https://openalex.org/A5066756448"],"corresponding_institution_ids":["https://openalex.org/I40120149","https://openalex.org/I4210103985","https://openalex.org/I79817857"],"apc_list":{"value":1500,"currency":"GBP","value_usd":1839},"apc_paid":{"value":1500,"currency":"GBP","value_usd":1839},"fwci":5.5581,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.96966003,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"15","issue":"1","first_page":"240310","last_page":"240310"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.35249999165534973,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.35249999165534973,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10943","display_name":"Escherichia coli research studies","score":0.2498999983072281,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.14810000360012054,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/enterobacterial-common-antigen","display_name":"enterobacterial common antigen","score":0.8679999709129333},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.8029999732971191},{"id":"https://openalex.org/keywords/membrane-protein-structure","display_name":"membrane protein structure","score":0.5649999976158142},{"id":"https://openalex.org/keywords/translocation-mechanism","display_name":"translocation mechanism","score":0.7609999775886536}],"concepts":[{"id":"https://openalex.org/C2777019660","wikidata":"https://www.wikidata.org/wiki/Q106947147","display_name":"Flippase","level":5,"score":0.8562536239624023},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8223644495010376},{"id":"https://openalex.org/C131934819","wikidata":"https://www.wikidata.org/wiki/Q135390","display_name":"Biogenesis","level":3,"score":0.7111240029335022},{"id":"https://openalex.org/C2780183148","wikidata":"https://www.wikidata.org/wiki/Q21099571","display_name":"Lipid II","level":4,"score":0.60330730676651},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.4938133656978607},{"id":"https://openalex.org/C146587185","wikidata":"https://www.wikidata.org/wiki/Q258248","display_name":"Bacterial outer membrane","level":4,"score":0.490845263004303},{"id":"https://openalex.org/C206212055","wikidata":"https://www.wikidata.org/wiki/Q2553138","display_name":"Glycan","level":3,"score":0.4810795485973358},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4569878578186035},{"id":"https://openalex.org/C33292294","wikidata":"https://www.wikidata.org/wiki/Q21760416","display_name":"Twin-arginine translocation pathway","level":5,"score":0.4407691955566406},{"id":"https://openalex.org/C144647389","wikidata":"https://www.wikidata.org/wiki/Q423042","display_name":"Membrane protein","level":3,"score":0.3015349507331848},{"id":"https://openalex.org/C553450214","wikidata":"https://www.wikidata.org/wiki/Q851162","display_name":"Biosynthesis","level":3,"score":0.22706571221351624},{"id":"https://openalex.org/C115335371","wikidata":"https://www.wikidata.org/wiki/Q142943","display_name":"Membrane transport protein","level":4,"score":0.16783323884010315},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.16042548418045044},{"id":"https://openalex.org/C2778918659","wikidata":"https://www.wikidata.org/wiki/Q186915","display_name":"Phospholipid","level":3,"score":0.15697461366653442},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.12333282828330994},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11556097865104675},{"id":"https://openalex.org/C2779637612","wikidata":"https://www.wikidata.org/wiki/Q2354337","display_name":"Phosphatidylserine","level":4,"score":0.07749652862548828},{"id":"https://openalex.org/C108625454","wikidata":"https://www.wikidata.org/wiki/Q187126","display_name":"Glycoprotein","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000942","descriptor_name":"Antigens, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000942","descriptor_name":"Antigens, Bacterial","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000942","descriptor_name":"Antigens, Bacterial","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001120","descriptor_name":"Arginine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001120","descriptor_name":"Arginine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029968","descriptor_name":"Escherichia coli Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D029968","descriptor_name":"Escherichia coli Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D029968","descriptor_name":"Escherichia coli Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1098/rsob.240310","doi":"https://doi.org/10.1098/rsob.240310","is_oa":true,"landing_page_url":"https://doi.org/10.1098/rsob.240310","pdf_url":null,"source":{"id":"https://openalex.org/S80033963","display_name":"Open Biology","issn_l":"2046-2441","issn":["2046-2441"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319787","host_organization_name":"Royal Society","host_organization_lineage":["https://openalex.org/P4310319787"],"host_organization_lineage_names":["Royal Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Biology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11706664","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11706664","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11706664/pdf/rsob.240310.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Biol","raw_type":"Text"},{"id":"pmid:39772807","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39772807","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open biology","raw_type":"Journal Article"},{"id":"pmh:oai:ora.ox.ac.uk:uuid:4d846c5b-f982-4bd8-8d4f-71a49f31a837","doi":null,"is_oa":true,"landing_page_url":"https://ora.ox.ac.uk/objects/uuid:4d846c5b-f982-4bd8-8d4f-71a49f31a837/files/rmw22v670v","pdf_url":"https://ora.ox.ac.uk/objects/uuid:4d846c5b-f982-4bd8-8d4f-71a49f31a837/files/rmw22v670v","source":{"id":"https://openalex.org/S4306402636","display_name":"Oxford University Research Archive (ORA) (University of Oxford)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I40120149","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/I40120149"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Jisc Publications Router","raw_type":"Journal article"},{"id":"pmh:oai:vubissmart:VUBISSMART:2000:180607","doi":null,"is_oa":true,"landing_page_url":"https://biblio.vub.ac.be/vubir/structure-of-wzxe-the-lipid-iii-flippase-for-enterobacterial-common-antigen-polysaccharide(5fb476b1-ab9a-47f0-8eb1-d342f817ccde).html","pdf_url":"https://biblio.vub.ac.be/vubirfiles/235920533/121295865.pdf","source":{"id":"https://openalex.org/S4306402573","display_name":"VUBIR (Vrije Universiteit Brussel)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I13469542","host_organization_name":"Vrije Universiteit Brussel","host_organization_lineage":["https://openalex.org/I13469542"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:94b46bf40d754479b461ae3ad9de611d","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/94b46bf40d754479b461ae3ad9de611d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Open Biology, Vol 15, Iss 1 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1098/rsob.240310","doi":"https://doi.org/10.1098/rsob.240310","is_oa":true,"landing_page_url":"https://doi.org/10.1098/rsob.240310","pdf_url":null,"source":{"id":"https://openalex.org/S80033963","display_name":"Open Biology","issn_l":"2046-2441","issn":["2046-2441"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319787","host_organization_name":"Royal Society","host_organization_lineage":["https://openalex.org/P4310319787"],"host_organization_lineage_names":["Royal Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G113182007","display_name":"A membrane protein laboratory for integrative structural biology","funder_award_id":"223727/Z/21/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G3859189604","display_name":"A laboratory for membrane protein structural biology","funder_award_id":"202892/Z/16/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G787615749","display_name":"Electrifying Life Science","funder_award_id":"220526/Z/20/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G9000071214","display_name":null,"funder_award_id":"100209/Z/12/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320313096","display_name":"Diamond Light Source","ror":"https://ror.org/05etxs293"},{"id":"https://openalex.org/F4320320994","display_name":"Canada Research Chairs","ror":"https://ror.org/0517h6h17"},{"id":"https://openalex.org/F4320321730","display_name":"Fonds Wetenschappelijk Onderzoek","ror":"https://ror.org/03qtxy027"},{"id":"https://openalex.org/F4320334506","display_name":"Canadian Institutes of Health Research","ror":"https://ror.org/01gavpb45"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4406135884.pdf","grobid_xml":"https://content.openalex.org/works/W4406135884.grobid-xml"},"referenced_works_count":94,"referenced_works":["https://openalex.org/W1189912934","https://openalex.org/W1482784055","https://openalex.org/W1537398925","https://openalex.org/W1550911355","https://openalex.org/W1591127765","https://openalex.org/W1606807103","https://openalex.org/W1911934392","https://openalex.org/W1990991313","https://openalex.org/W1992956599","https://openalex.org/W1997111429","https://openalex.org/W1998292458","https://openalex.org/W2006922696","https://openalex.org/W2013676328","https://openalex.org/W2018289835","https://openalex.org/W2019425225","https://openalex.org/W2030632688","https://openalex.org/W2040912096","https://openalex.org/W2041886444","https://openalex.org/W2047478935","https://openalex.org/W2070170641","https://openalex.org/W2097226393","https://openalex.org/W2098428537","https://openalex.org/W2099329633","https://openalex.org/W2100837269","https://openalex.org/W2101871915","https://openalex.org/W2102084678","https://openalex.org/W2103369433","https://openalex.org/W2103714813","https://openalex.org/W2104655156","https://openalex.org/W2108608900","https://openalex.org/W2108921801","https://openalex.org/W2109160052","https://openalex.org/W2112562361","https://openalex.org/W2113908179","https://openalex.org/W2120772351","https://openalex.org/W2127470269","https://openalex.org/W2129583295","https://openalex.org/W2132629607","https://openalex.org/W2139942857","https://openalex.org/W2140295865","https://openalex.org/W2143815085","https://openalex.org/W2144559370","https://openalex.org/W2151436324","https://openalex.org/W2153781183","https://openalex.org/W2159211495","https://openalex.org/W2160084442","https://openalex.org/W2161902864","https://openalex.org/W2163341755","https://openalex.org/W2168974130","https://openalex.org/W2174282801","https://openalex.org/W2276180411","https://openalex.org/W2513199622","https://openalex.org/W2519097502","https://openalex.org/W2565680183","https://openalex.org/W2607005831","https://openalex.org/W2735270119","https://openalex.org/W2735876928","https://openalex.org/W2753791808","https://openalex.org/W2765322245","https://openalex.org/W2770618149","https://openalex.org/W2783535000","https://openalex.org/W2808539404","https://openalex.org/W2808709689","https://openalex.org/W2913900430","https://openalex.org/W2917512698","https://openalex.org/W2945262470","https://openalex.org/W2948339609","https://openalex.org/W2951041301","https://openalex.org/W2973457155","https://openalex.org/W2995123180","https://openalex.org/W3048517330","https://openalex.org/W3119448550","https://openalex.org/W3138062116","https://openalex.org/W3159992438","https://openalex.org/W3170191428","https://openalex.org/W3177828909","https://openalex.org/W3197891171","https://openalex.org/W3211372884","https://openalex.org/W3211795435","https://openalex.org/W4221080428","https://openalex.org/W4224063546","https://openalex.org/W4224950059","https://openalex.org/W4248872320","https://openalex.org/W4255677297","https://openalex.org/W4281744366","https://openalex.org/W4290861674","https://openalex.org/W4309506674","https://openalex.org/W4313829222","https://openalex.org/W4313893926","https://openalex.org/W4319460994","https://openalex.org/W4328054256","https://openalex.org/W4387581489","https://openalex.org/W4394694796","https://openalex.org/W6902507702"],"related_works":["https://openalex.org/W6921017540","https://openalex.org/W6939864309","https://openalex.org/W2108608900","https://openalex.org/W2019534061","https://openalex.org/W2127470269","https://openalex.org/W4409334105","https://openalex.org/W4328054256","https://openalex.org/W2157995916","https://openalex.org/W7098816225","https://openalex.org/W4224950059"],"abstract_inverted_index":{"The":[0],"enterobacterial":[1],"common":[2],"antigen":[3],"(ECA)":[4],"is":[5,17,48,68,122],"conserved":[6],"in":[7,56,89,106],"Gram-negative":[8],"bacteria":[9],"of":[10,50,64,74,84,101,113,138,148],"the":[11,23,27,38,42,51,80,114,128,136,139,145,149],"Enterobacterales":[12],"order":[13],"although":[14],"its":[15,65],"function":[16],"debated.":[18],"ECA":[19],"biogenesis":[20],"depends":[21],"on":[22],"Wzx/Wzy-dependent":[24],"strategy":[25],"whereby":[26],"newly":[28],"synthesized":[29],"lipid-linked":[30],"repeat":[31],"units,":[32],"lipid":[33,43],"III,":[34],"are":[35],"transferred":[36],"across":[37],"inner":[39],"membrane":[40],"by":[41],"III":[44],"flippase":[45,151],"WzxE.":[46],"WzxE":[47,85],"part":[49],"Wzx":[52,150],"family":[53],"and":[54,95],"required":[55],"many":[57],"glycan":[58],"assembly":[59],"systems,":[60],"but":[61],"an":[62],"understanding":[63],"molecular":[66],"mechanism":[67,147],"hindered":[69],"due":[70],"to":[71,118,135],"a":[72,107,119],"lack":[73],"structural":[75],"evidence.":[76],"Here,":[77],"we":[78],"present":[79],"first":[81],"X-ray":[82],"structures":[83],"from":[86],"Escherichia":[87],"coli":[88],"complex":[90],"with":[91,127],"nanobodies.":[92],"Both":[93],"inward-":[94],"outward-facing":[96],"conformations":[97],"highlight":[98],"two":[99],"pairs":[100,116],"arginine":[102,115,130],"residues":[103],"that":[104],"move":[105],"reciprocal":[108],"fashion,":[109],"enabling":[110],"flipping.":[111],"One":[112],"coordinated":[117],"glutamate":[120],"residue":[121],"essential":[123],"for":[124],"activity":[125],"along":[126],"C-terminal":[129],"rich":[131],"tail":[132],"located":[133],"close":[134],"entrance":[137],"lumen.":[140],"This":[141],"work":[142],"helps":[143],"understand":[144],"translocation":[146],"family.":[152]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":4}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2025-01-08T00:00:00"}