{"id":"https://openalex.org/W4405751012","doi":"https://doi.org/10.1016/j.jval.2024.10.3688","title":"RWD130 Elacestrant vs Everolimus + Exemestane in Patients With ER+/HER2- ESR1-Mutated Advanced/Metastatic Breast Cancer (mBC) With Prior Endocrine Therapy + CDK4/6 Inhibitor \u226512 Months: Combining Real-World and Clinical Trial Data","display_name":"RWD130 Elacestrant vs Everolimus + Exemestane in Patients With ER+/HER2- ESR1-Mutated Advanced/Metastatic Breast Cancer (mBC) With Prior Endocrine Therapy + CDK4/6 Inhibitor \u226512 Months: Combining Real-World and Clinical Trial Data","publication_year":2024,"publication_date":"2024-12-01","ids":{"openalex":"https://openalex.org/W4405751012","doi":"https://doi.org/10.1016/j.jval.2024.10.3688"},"language":"en","primary_location":{"id":"doi:10.1016/j.jval.2024.10.3688","doi":"https://doi.org/10.1016/j.jval.2024.10.3688","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jval.2024.10.3688","pdf_url":null,"source":{"id":"https://openalex.org/S678965","display_name":"Value in Health","issn_l":"1098-3015","issn":["1098-3015","1524-4733"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["abdc-a","anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Value in Health","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/j.jval.2024.10.3688","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021888589","display_name":"Federico Felizzi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108499","display_name":"Menarini Group (Italy)","ror":"https://ror.org/02h1wg091","country_code":"IT","type":"company","lineage":["https://openalex.org/I4210108499"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"F. Felizzi","raw_affiliation_strings":["Menarini Group, Florence, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Menarini Group, Florence, Italy","institution_ids":["https://openalex.org/I4210108499"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085700120","display_name":"Elisabetta Fenu","orcid":"https://orcid.org/0000-0001-7666-3319","observed_orcids":["https://orcid.org/0000-0001-7666-3319"]},"institutions":[{"id":"https://openalex.org/I4210108499","display_name":"Menarini Group (Italy)","ror":"https://ror.org/02h1wg091","country_code":"IT","type":"company","lineage":["https://openalex.org/I4210108499"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"E. Fenu","raw_affiliation_strings":["Menarini Group, Florence, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Menarini Group, Florence, Italy","institution_ids":["https://openalex.org/I4210108499"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015307324","display_name":"Susanne Kloss","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108499","display_name":"Menarini Group (Italy)","ror":"https://ror.org/02h1wg091","country_code":"IT","type":"company","lineage":["https://openalex.org/I4210108499"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"S. Kloss","raw_affiliation_strings":["Menarini Group, Florence, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Menarini Group, Florence, Italy","institution_ids":["https://openalex.org/I4210108499"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115630983","display_name":"Valentine Laizet","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V. Laizet","raw_affiliation_strings":["Amaris Consulting, Geneva, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Amaris Consulting, Geneva, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010575426","display_name":"Pauline Le Nouveau","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P. Le Nouveau","raw_affiliation_strings":["Amaris Consulting, Geneva, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Amaris Consulting, Geneva, Switzerland","institution_ids":[]}]},{"author_position":"last","author":{"id":null,"display_name":"S. Moreno","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108499","display_name":"Menarini Group (Italy)","ror":"https://ror.org/02h1wg091","country_code":"IT","type":"company","lineage":["https://openalex.org/I4210108499"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"S. Moreno","raw_affiliation_strings":["Menarini Group, Florence, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Menarini Group, Florence, Italy","institution_ids":["https://openalex.org/I4210108499"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3200,"currency":"USD","value_usd":3200},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"27","issue":"12","first_page":"S598","last_page":"S598"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12829","display_name":"Advanced Breast Cancer Therapies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12829","display_name":"Advanced Breast Cancer Therapies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11914","display_name":"PARP inhibition in cancer therapy","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/elacestrant","display_name":"elacestrant","score":0.9869999885559082},{"id":"https://openalex.org/keywords/everolimus","display_name":"everolimus","score":0.9660000205039978},{"id":"https://openalex.org/keywords/exemestane","display_name":"exemestane","score":0.9990000128746033},{"id":"https://openalex.org/keywords/er-positive-her2-negative-breast-cancer","display_name":"ER-positive HER2-negative breast cancer","score":0.7739999890327454},{"id":"https://openalex.org/keywords/esr1-mutations","display_name":"ESR1 mutations","score":0.9309999942779541},{"id":"https://openalex.org/keywords/cdk4-6-inhibitors","display_name":"CDK4/6 inhibitors","score":0.8429999947547913},{"id":"https://openalex.org/keywords/endocrine-therapy","display_name":"endocrine therapy","score":0.8130000233650208},{"id":"https://openalex.org/keywords/real-world-data","display_name":"real-world data","score":0.7509999871253967},{"id":"https://openalex.org/keywords/clinical-trial-data-integration","display_name":"clinical trial data integration","score":0.6430000066757202}],"concepts":[{"id":"https://openalex.org/C2775860665","wikidata":"https://www.wikidata.org/wiki/Q418819","display_name":"Exemestane","level":5,"score":0.9196144938468933},{"id":"https://openalex.org/C2779699572","wikidata":"https://www.wikidata.org/wiki/Q421052","display_name":"Everolimus","level":2,"score":0.7981929183006287},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7386565208435059},{"id":"https://openalex.org/C2775930923","wikidata":"https://www.wikidata.org/wiki/Q12859063","display_name":"Metastatic breast cancer","level":4,"score":0.6933823227882385},{"id":"https://openalex.org/C2778504769","wikidata":"https://www.wikidata.org/wiki/Q3040305","display_name":"Aromatase inhibitor","level":5,"score":0.6738851070404053},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.6058732867240906},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.508051872253418},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4983968734741211},{"id":"https://openalex.org/C2778812593","wikidata":"https://www.wikidata.org/wiki/Q194974","display_name":"Letrozole","level":5,"score":0.49627286195755005},{"id":"https://openalex.org/C2779744173","wikidata":"https://www.wikidata.org/wiki/Q15269707","display_name":"Palbociclib","level":5,"score":0.4827932119369507},{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.4604973793029785},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.4045370817184448},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3633359968662262},{"id":"https://openalex.org/C2776166826","wikidata":"https://www.wikidata.org/wiki/Q415287","display_name":"Aromatase","level":4,"score":0.2507590651512146},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.0769854485988617}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jval.2024.10.3688","doi":"https://doi.org/10.1016/j.jval.2024.10.3688","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jval.2024.10.3688","pdf_url":null,"source":{"id":"https://openalex.org/S678965","display_name":"Value in Health","issn_l":"1098-3015","issn":["1098-3015","1524-4733"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["abdc-a","anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Value in Health","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.jval.2024.10.3688","doi":"https://doi.org/10.1016/j.jval.2024.10.3688","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jval.2024.10.3688","pdf_url":null,"source":{"id":"https://openalex.org/S678965","display_name":"Value in Health","issn_l":"1098-3015","issn":["1098-3015","1524-4733"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["abdc-a","anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Value in Health","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7212885194","https://openalex.org/W4416239499","https://openalex.org/W4411288808","https://openalex.org/W4410805389","https://openalex.org/W4399323640","https://openalex.org/W4396591679","https://openalex.org/W4405107382","https://openalex.org/W4410463539","https://openalex.org/W7129252518","https://openalex.org/W7154735291"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2024-12-25T00:00:00"}