{"id":"https://openalex.org/W4405636611","doi":"https://doi.org/10.1016/j.nsa.2024.104635","title":"Effect of KarXT on social functioning and life engagement in schizophrenia: post hoc pooled analysis from the EMERGENT trials","display_name":"Effect of KarXT on social functioning and life engagement in schizophrenia: post hoc pooled analysis from the EMERGENT trials","publication_year":2024,"publication_date":"2024-01-01","ids":{"openalex":"https://openalex.org/W4405636611","doi":"https://doi.org/10.1016/j.nsa.2024.104635"},"language":"en","primary_location":{"id":"doi:10.1016/j.nsa.2024.104635","doi":"https://doi.org/10.1016/j.nsa.2024.104635","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.nsa.2024.104635","pdf_url":null,"source":{"id":"https://openalex.org/S4210236820","display_name":"Neuroscience Applied","issn_l":"2772-4085","issn":["2772-4085"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience Applied","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.nsa.2024.104635","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037178786","display_name":"C.U. Correll","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210106353","display_name":"Donald & Barbara Zucker School of Medicine at Hofstra/Northwell","ror":"https://ror.org/01ff5td15","country_code":"US","type":"education","lineage":["https://openalex.org/I1302444339","https://openalex.org/I139290212","https://openalex.org/I4210106353"]},{"id":"https://openalex.org/I4210166545","display_name":"Zucker Hillside Hospital","ror":"https://ror.org/05vh9vp33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1302444339","https://openalex.org/I4210166545"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"C.U. Correll","raw_affiliation_strings":["Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Psychiatry, Berlin, Germany","Donald And Barbara Zucker School of Medicine at Hofstra/Northwell, Psychiatry, Hempstead- NY, United States","The Zucker Hillside Hospital, Psychiatry, Glen Oaks- NY, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Psychiatry, Berlin, Germany","institution_ids":["https://openalex.org/I7877124"]},{"raw_affiliation_string":"Donald And Barbara Zucker School of Medicine at Hofstra/Northwell, Psychiatry, Hempstead- NY, United States","institution_ids":["https://openalex.org/I4210106353"]},{"raw_affiliation_string":"The Zucker Hillside Hospital, Psychiatry, Glen Oaks- NY, United States","institution_ids":["https://openalex.org/I4210166545"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082482780","display_name":"Gerard A. Zitnik","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091812","display_name":"Bristol-Myers Squibb (United States)","ror":"https://ror.org/00gtmwv55","country_code":"US","type":"company","lineage":["https://openalex.org/I4210091812"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G. Zitnik","raw_affiliation_strings":["Bristol Myers Squibb, Medical Affairs, Princeton- NJ, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bristol Myers Squibb, Medical Affairs, Princeton- NJ, United States","institution_ids":["https://openalex.org/I4210091812"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013823790","display_name":"Scott C. Vuocolo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091812","display_name":"Bristol-Myers Squibb (United States)","ror":"https://ror.org/00gtmwv55","country_code":"US","type":"company","lineage":["https://openalex.org/I4210091812"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Vuocolo","raw_affiliation_strings":["Bristol Myers Squibb, Medical Affairs, Princeton- NJ, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bristol Myers Squibb, Medical Affairs, Princeton- NJ, United States","institution_ids":["https://openalex.org/I4210091812"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072357866","display_name":"Chetan P. Shah","orcid":"https://orcid.org/0000-0001-8074-7697","observed_orcids":["https://orcid.org/0000-0001-8074-7697"]},"institutions":[{"id":"https://openalex.org/I4210091812","display_name":"Bristol-Myers Squibb (United States)","ror":"https://ror.org/00gtmwv55","country_code":"US","type":"company","lineage":["https://openalex.org/I4210091812"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Shah","raw_affiliation_strings":["Bristol Myers Squibb, Medical Affairs, Princeton- NJ, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bristol Myers Squibb, Medical Affairs, Princeton- NJ, United States","institution_ids":["https://openalex.org/I4210091812"]}]},{"author_position":"last","author":{"id":null,"display_name":"K. Kramer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091812","display_name":"Bristol-Myers Squibb (United States)","ror":"https://ror.org/00gtmwv55","country_code":"US","type":"company","lineage":["https://openalex.org/I4210091812"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K. Kramer","raw_affiliation_strings":["Bristol Myers Squibb, Medical Affairs, Princeton- NJ, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bristol Myers Squibb, Medical Affairs, Princeton- NJ, United States","institution_ids":["https://openalex.org/I4210091812"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2000,"currency":"USD","value_usd":2000},"apc_paid":{"value":2000,"currency":"USD","value_usd":2000},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.2817085,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"3","issue":null,"first_page":"104635","last_page":"104635"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12308","display_name":"Mental Health and Psychiatry","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1211","display_name":"Philosophy"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/xanomeline-trospium","display_name":"KarXT","score":0.9430000185966492},{"id":"https://openalex.org/keywords/cariprazine","display_name":"cariprazine","score":0.5720000267028809},{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.7210000157356262},{"id":"https://openalex.org/keywords/social-functioning","display_name":"social functioning","score":0.9950000047683716},{"id":"https://openalex.org/keywords/life-engagement","display_name":"life engagement","score":0.9760000109672546},{"id":"https://openalex.org/keywords/antipsychotic-drugs","display_name":"antipsychotic drugs","score":0.6489999890327454},{"id":"https://openalex.org/keywords/pooled-analysis","display_name":"pooled analysis","score":0.4269999861717224}],"concepts":[{"id":"https://openalex.org/C67761136","wikidata":"https://www.wikidata.org/wiki/Q2105849","display_name":"Post-hoc analysis","level":2,"score":0.8180233836174011},{"id":"https://openalex.org/C2992886853","wikidata":"https://www.wikidata.org/wiki/Q18381816","display_name":"Post hoc","level":2,"score":0.6868799924850464},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.6433246731758118},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6316409111022949},{"id":"https://openalex.org/C2992104508","wikidata":"https://www.wikidata.org/wiki/Q1413287","display_name":"Social functioning","level":3,"score":0.5216679573059082},{"id":"https://openalex.org/C9701087","wikidata":"https://www.wikidata.org/wiki/Q1283504","display_name":"Social engagement","level":2,"score":0.48438674211502075},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.3761727511882782},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.35780835151672363},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.2952946424484253},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.21594533324241638},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.205802321434021},{"id":"https://openalex.org/C36289849","wikidata":"https://www.wikidata.org/wiki/Q34749","display_name":"Social science","level":1,"score":0.09519386291503906},{"id":"https://openalex.org/C139265228","wikidata":"https://www.wikidata.org/wiki/Q5283089","display_name":"Distress","level":2,"score":0.0},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.nsa.2024.104635","doi":"https://doi.org/10.1016/j.nsa.2024.104635","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.nsa.2024.104635","pdf_url":null,"source":{"id":"https://openalex.org/S4210236820","display_name":"Neuroscience Applied","issn_l":"2772-4085","issn":["2772-4085"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience Applied","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.nsa.2024.104635","doi":"https://doi.org/10.1016/j.nsa.2024.104635","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.nsa.2024.104635","pdf_url":null,"source":{"id":"https://openalex.org/S4210236820","display_name":"Neuroscience Applied","issn_l":"2772-4085","issn":["2772-4085"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience Applied","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4313200280","https://openalex.org/W4310033228","https://openalex.org/W4390241689","https://openalex.org/W7057124102","https://openalex.org/W7117971827","https://openalex.org/W4399273384","https://openalex.org/W4309651428","https://openalex.org/W868844782","https://openalex.org/W2092151592","https://openalex.org/W2293454475"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-22T18:32:59.640997","created_date":"2024-12-21T00:00:00"}