{"id":"https://openalex.org/W4405510752","doi":"https://doi.org/10.1007/s00296-024-05750-x","title":"New onset heart failure in adolescents with inflammatory joint disease treated with TNF-\u03b1 inhibitors: a case-based review","display_name":"New onset heart failure in adolescents with inflammatory joint disease treated with TNF-\u03b1 inhibitors: a case-based review","publication_year":2024,"publication_date":"2024-12-18","ids":{"openalex":"https://openalex.org/W4405510752","doi":"https://doi.org/10.1007/s00296-024-05750-x","pmid":"https://pubmed.ncbi.nlm.nih.gov/39692771"},"language":"en","primary_location":{"id":"doi:10.1007/s00296-024-05750-x","doi":"https://doi.org/10.1007/s00296-024-05750-x","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00296-024-05750-x","pdf_url":null,"source":{"id":"https://openalex.org/S50823678","display_name":"Rheumatology International","issn_l":"0172-8172","issn":["0172-8172","1437-160X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rheumatology International","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040260173","display_name":"Sophie I. Mavrogeni","orcid":"https://orcid.org/0000-0003-1089-7766","observed_orcids":["https://orcid.org/0000-0003-1089-7766"]},"institutions":[{"id":"https://openalex.org/I4210117383","display_name":"Onassis Cardiac Surgery Center","ror":"https://ror.org/02gan0k07","country_code":"GR","type":"healthcare","lineage":["https://openalex.org/I4210117383"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Sophie Mavrogeni","raw_affiliation_strings":["Onassis Cardiac Surgery Center, Athens, Greece"],"raw_orcid":"https://orcid.org/0000-0003-1089-7766","affiliations":[{"raw_affiliation_string":"Onassis Cardiac Surgery Center, Athens, Greece","institution_ids":["https://openalex.org/I4210117383"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020672371","display_name":"Evdoxia Sapountzi","orcid":"https://orcid.org/0000-0002-1566-4366","observed_orcids":["https://orcid.org/0000-0002-1566-4366"]},"institutions":[{"id":"https://openalex.org/I21370196","display_name":"Aristotle University of Thessaloniki","ror":"https://ror.org/02j61yw88","country_code":"GR","type":"education","lineage":["https://openalex.org/I21370196"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Evdoxia Sapountzi","raw_affiliation_strings":["2nd Department of Pediatrics, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, AHEPA General Hospital, Thessaloniki, Greece"],"raw_orcid":"https://orcid.org/0000-0002-1566-4366","affiliations":[{"raw_affiliation_string":"2nd Department of Pediatrics, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, AHEPA General Hospital, Thessaloniki, Greece","institution_ids":["https://openalex.org/I21370196"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106648112","display_name":"Kyveli Chiotopoulou","orcid":"https://orcid.org/0009-0002-8458-9555","observed_orcids":["https://orcid.org/0009-0002-8458-9555"]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]},{"id":"https://openalex.org/I4210140282","display_name":"University General Hospital Attikon","ror":"https://ror.org/03gb7n667","country_code":"GR","type":"healthcare","lineage":["https://openalex.org/I4210140282"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Kyveli Chiotopoulou","raw_affiliation_strings":["Division of Pediatric Rheumatology, Department of Pediatrics, Attikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece"],"raw_orcid":"https://orcid.org/0009-0002-8458-9555","affiliations":[{"raw_affiliation_string":"Division of Pediatric Rheumatology, Department of Pediatrics, Attikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece","institution_ids":["https://openalex.org/I200777214","https://openalex.org/I4210140282"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025371094","display_name":"Lampros Fotis","orcid":"https://orcid.org/0000-0001-7171-6119","observed_orcids":["https://orcid.org/0000-0001-7171-6119"]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]},{"id":"https://openalex.org/I4210140282","display_name":"University General Hospital Attikon","ror":"https://ror.org/03gb7n667","country_code":"GR","type":"healthcare","lineage":["https://openalex.org/I4210140282"]}],"countries":["GR"],"is_corresponding":true,"raw_author_name":"Lampros Fotis","raw_affiliation_strings":["Division of Pediatric Rheumatology, Department of Pediatrics, Attikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece. lafotis@med.uoa.gr","Division of Pediatric Rheumatology, Department of Pediatrics, Attikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece"],"raw_orcid":"https://orcid.org/0000-0001-7171-6119","affiliations":[{"raw_affiliation_string":"Division of Pediatric Rheumatology, Department of Pediatrics, Attikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece. lafotis@med.uoa.gr","institution_ids":["https://openalex.org/I200777214","https://openalex.org/I4210140282"]},{"raw_affiliation_string":"Division of Pediatric Rheumatology, Department of Pediatrics, Attikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece","institution_ids":["https://openalex.org/I200777214","https://openalex.org/I4210140282"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5025371094"],"corresponding_institution_ids":["https://openalex.org/I200777214","https://openalex.org/I4210140282"],"apc_list":{"value":4790,"currency":"USD","value_usd":4790},"apc_paid":null,"fwci":0.7657,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.68390753,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"45","issue":"1","first_page":"4","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11616","display_name":"Autoimmune and Inflammatory Disorders Research","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heart-failure","display_name":"heart failure","score":0.9419999718666077},{"id":"https://openalex.org/keywords/tnf-alpha-inhibitors","display_name":"TNF-alpha inhibitors","score":0.8360000252723694},{"id":"https://openalex.org/keywords/adolescents","display_name":"adolescents","score":0.5770000219345093},{"id":"https://openalex.org/keywords/ankylosing-spondylitis","display_name":"ankylosing spondylitis","score":0.9079999923706055},{"id":"https://openalex.org/keywords/juvenile-idiopathic-arthritis","display_name":"juvenile idiopathic arthritis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/adalimumab","display_name":"adalimumab","score":0.9380000233650208},{"id":"https://openalex.org/keywords/etanercept","display_name":"etanercept","score":1.0},{"id":"https://openalex.org/keywords/secukinumab","display_name":"secukinumab","score":0.9909999966621399},{"id":"https://openalex.org/keywords/tocilizumab","display_name":"tocilizumab","score":1.0},{"id":"https://openalex.org/keywords/myocarditis","display_name":"myocarditis","score":0.9490000009536743},{"id":"https://openalex.org/keywords/adverse-cardiovascular-events","display_name":"cardiovascular adverse events","score":0.7730000019073486},{"id":"https://openalex.org/keywords/cardiac-monitoring","display_name":"cardiac monitoring","score":0.46299999952316284}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9660238027572632},{"id":"https://openalex.org/C2780132546","wikidata":"https://www.wikidata.org/wiki/Q348260","display_name":"Adalimumab","level":3,"score":0.8245934247970581},{"id":"https://openalex.org/C2777226972","wikidata":"https://www.wikidata.org/wiki/Q415343","display_name":"Etanercept","level":3,"score":0.8151129484176636},{"id":"https://openalex.org/C2777402515","wikidata":"https://www.wikidata.org/wiki/Q52849","display_name":"Ankylosing spondylitis","level":2,"score":0.7700142860412598},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.7360998392105103},{"id":"https://openalex.org/C2778715236","wikidata":"https://www.wikidata.org/wiki/Q55622662","display_name":"Discontinuation","level":2,"score":0.6741355061531067},{"id":"https://openalex.org/C2777178219","wikidata":"https://www.wikidata.org/wiki/Q425154","display_name":"Tocilizumab","level":3,"score":0.6581177711486816},{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.6264252662658691},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6135728359222412},{"id":"https://openalex.org/C198451711","wikidata":"https://www.wikidata.org/wiki/Q327657","display_name":"Rheumatology","level":2,"score":0.5512194037437439},{"id":"https://openalex.org/C2778917330","wikidata":"https://www.wikidata.org/wiki/Q1274464","display_name":"Polyarthritis","level":3,"score":0.5510073304176331},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.47323641180992126},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.4658103287220001},{"id":"https://openalex.org/C2777077863","wikidata":"https://www.wikidata.org/wiki/Q170990","display_name":"Arthritis","level":2,"score":0.46204042434692383},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4556898772716522},{"id":"https://openalex.org/C2779786854","wikidata":"https://www.wikidata.org/wiki/Q7444755","display_name":"Secukinumab","level":4,"score":0.43449434638023376},{"id":"https://openalex.org/C2781228260","wikidata":"https://www.wikidata.org/wiki/Q415411","display_name":"Anakinra","level":3,"score":0.428462952375412},{"id":"https://openalex.org/C2777138892","wikidata":"https://www.wikidata.org/wiki/Q415264","display_name":"Infliximab","level":3,"score":0.42433348298072815},{"id":"https://openalex.org/C111566952","wikidata":"https://www.wikidata.org/wiki/Q1303462","display_name":"Cardiac function curve","level":3,"score":0.42041414976119995},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.39502614736557007},{"id":"https://openalex.org/C2776260265","wikidata":"https://www.wikidata.org/wiki/Q511097","display_name":"Psoriatic arthritis","level":3,"score":0.2427835762500763},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000068800","descriptor_name":"Etanercept","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000068800","descriptor_name":"Etanercept","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000068879","descriptor_name":"Adalimumab","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000068879","descriptor_name":"Adalimumab","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001171","descriptor_name":"Arthritis, Juvenile","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D001171","descriptor_name":"Arthritis, Juvenile","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013167","descriptor_name":"Spondylitis, Ankylosing","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D018501","descriptor_name":"Antirheumatic Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D018501","descriptor_name":"Antirheumatic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D061067","descriptor_name":"Antibodies, Monoclonal, Humanized","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D061067","descriptor_name":"Antibodies, Monoclonal, Humanized","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s00296-024-05750-x","doi":"https://doi.org/10.1007/s00296-024-05750-x","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00296-024-05750-x","pdf_url":null,"source":{"id":"https://openalex.org/S50823678","display_name":"Rheumatology International","issn_l":"0172-8172","issn":["0172-8172","1437-160X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rheumatology International","raw_type":"journal-article"},{"id":"pmid:39692771","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39692771","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rheumatology international","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W1966756501","https://openalex.org/W1970375970","https://openalex.org/W1983071999","https://openalex.org/W1987312456","https://openalex.org/W2022110941","https://openalex.org/W2046108377","https://openalex.org/W2046728940","https://openalex.org/W2062902390","https://openalex.org/W2095779004","https://openalex.org/W2102211749","https://openalex.org/W2102980544","https://openalex.org/W2108650270","https://openalex.org/W2123133143","https://openalex.org/W2128363109","https://openalex.org/W2130837495","https://openalex.org/W2131010436","https://openalex.org/W2147375728","https://openalex.org/W2149063806","https://openalex.org/W2158744699","https://openalex.org/W2334211886","https://openalex.org/W2409427481","https://openalex.org/W2410275489","https://openalex.org/W2472110032","https://openalex.org/W2497876789","https://openalex.org/W2512942811","https://openalex.org/W2775007530","https://openalex.org/W2782361381","https://openalex.org/W2806643091","https://openalex.org/W2808124956","https://openalex.org/W2809848767","https://openalex.org/W2891623007","https://openalex.org/W2894345161","https://openalex.org/W2900025409","https://openalex.org/W2902932442","https://openalex.org/W2937703638","https://openalex.org/W2941230658","https://openalex.org/W2953615310","https://openalex.org/W2961111920","https://openalex.org/W2965147486","https://openalex.org/W2971086071","https://openalex.org/W2981830759","https://openalex.org/W2994854594","https://openalex.org/W3032231438","https://openalex.org/W3114623621","https://openalex.org/W3148538161","https://openalex.org/W4200522151","https://openalex.org/W4210657972","https://openalex.org/W4225295243","https://openalex.org/W4232257199","https://openalex.org/W4237169206","https://openalex.org/W4302013581","https://openalex.org/W4321495729","https://openalex.org/W4377037140"],"related_works":["https://openalex.org/W2046728940","https://openalex.org/W2808124956","https://openalex.org/W2130837495","https://openalex.org/W2102980544","https://openalex.org/W4377037140","https://openalex.org/W1986479542","https://openalex.org/W2107661188","https://openalex.org/W1965884463","https://openalex.org/W1983071999","https://openalex.org/W2094740608"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2024-12-18T00:00:00"}