{"id":"https://openalex.org/W4405489218","doi":"https://doi.org/10.1109/embc53108.2024.10781640","title":"Left Ventricular Hemodynamics: Pre versus Post Mitral Valve Prolapse Repair","display_name":"Left Ventricular Hemodynamics: Pre versus Post Mitral Valve Prolapse Repair","publication_year":2024,"publication_date":"2024-07-15","ids":{"openalex":"https://openalex.org/W4405489218","doi":"https://doi.org/10.1109/embc53108.2024.10781640","pmid":"https://pubmed.ncbi.nlm.nih.gov/40039921"},"language":"en","primary_location":{"id":"doi:10.1109/embc53108.2024.10781640","doi":"https://doi.org/10.1109/embc53108.2024.10781640","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc53108.2024.10781640","pdf_url":null,"source":{"id":"https://openalex.org/S4363608786","display_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","issn_l":"2375-7477","issn":["2375-7477"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["doyens","jufo-1","ki-jl-1","medline","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080396321","display_name":"Seyed Babak Peighambari","orcid":"https://orcid.org/0009-0001-1398-0111","observed_orcids":["https://orcid.org/0009-0001-1398-0111"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Seyed Babak Peighambari","raw_affiliation_strings":["Texas A&M University,Department of Biomedical Engineering,College Station,TX,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Texas A&M University,Department of Biomedical Engineering,College Station,TX,USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023020277","display_name":"Tanmay Mukherjee","orcid":"https://orcid.org/0000-0002-0191-3878","observed_orcids":["https://orcid.org/0000-0002-0191-3878"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tanmay Mukherjee","raw_affiliation_strings":["Texas A&M University,Department of Biomedical Engineering,College Station,TX,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Texas A&M University,Department of Biomedical Engineering,College Station,TX,USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024450291","display_name":"Emilio A. Mendiola","orcid":"https://orcid.org/0000-0002-7774-0811","observed_orcids":["https://orcid.org/0000-0002-7774-0811"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emilio A. Mendiola","raw_affiliation_strings":["Texas A&M University,Department of Biomedical Engineering,College Station,TX,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Texas A&M University,Department of Biomedical Engineering,College Station,TX,USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019278445","display_name":"Farhad R. Nezami","orcid":"https://orcid.org/0000-0002-4210-3177","observed_orcids":["https://orcid.org/0000-0002-4210-3177"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Farhad R. Nezami","raw_affiliation_strings":["Harvard Medical School,Department of Surgery,Boston,MA,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harvard Medical School,Department of Surgery,Boston,MA,USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089885800","display_name":"Amr Darwish","orcid":"https://orcid.org/0000-0002-8540-1916","observed_orcids":["https://orcid.org/0000-0002-8540-1916"]},"institutions":[{"id":"https://openalex.org/I1295876152","display_name":"Houston Methodist","ror":"https://ror.org/027zt9171","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295876152"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amr Darwish","raw_affiliation_strings":["Houston Methodist,DeBakey Heart and Vascular Center,Houston,TX,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Houston Methodist,DeBakey Heart and Vascular Center,Houston,TX,USA","institution_ids":["https://openalex.org/I1295876152"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043965596","display_name":"Dipan J. Shah","orcid":"https://orcid.org/0000-0002-6179-2393","observed_orcids":["https://orcid.org/0000-0002-6179-2393"]},"institutions":[{"id":"https://openalex.org/I1295876152","display_name":"Houston Methodist","ror":"https://ror.org/027zt9171","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295876152"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dipan J. Shah","raw_affiliation_strings":["Houston Methodist,DeBakey Heart and Vascular Center,Houston,TX,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Houston Methodist,DeBakey Heart and Vascular Center,Houston,TX,USA","institution_ids":["https://openalex.org/I1295876152"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006348854","display_name":"Reza Avazmohammadi","orcid":"https://orcid.org/0000-0001-9787-1117","observed_orcids":["https://orcid.org/0000-0001-9787-1117"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Reza Avazmohammadi","raw_affiliation_strings":["Texas A&M University,Department of Biomedical Engineering,College Station,TX,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Texas A&M University,Department of Biomedical Engineering,College Station,TX,USA","institution_ids":["https://openalex.org/I91045830"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":7.2044,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.97324113,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":"2024","issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.004100000020116568,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mitral-valve-prolapse","display_name":"mitral valve prolapse","score":1.0},{"id":"https://openalex.org/keywords/mitral-valve-repair","display_name":"mitral valve repair","score":0.9739999771118164},{"id":"https://openalex.org/keywords/left-ventricular-hemodynamics","display_name":"left ventricular hemodynamics","score":0.9290000200271606},{"id":"https://openalex.org/keywords/phase-contrast-mri","display_name":"phase-contrast MRI","score":0.796999990940094},{"id":"https://openalex.org/keywords/cardiac-cine-mri","display_name":"cardiac cine MRI","score":0.7080000042915344},{"id":"https://openalex.org/keywords/mitral-regurgitation","display_name":"mitral regurgitation","score":0.8349999785423279},{"id":"https://openalex.org/keywords/cardiac-remodeling","display_name":"cardiac remodeling","score":0.7329999804496765},{"id":"https://openalex.org/keywords/left-ventricular-function","display_name":"left ventricular function","score":0.6859999895095825}],"concepts":[{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.7232648134231567},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6830012798309326},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6315647959709167},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.486085444688797},{"id":"https://openalex.org/C2781030672","wikidata":"https://www.wikidata.org/wiki/Q735652","display_name":"Mitral valve prolapse","level":3,"score":0.4701801836490631},{"id":"https://openalex.org/C2780679668","wikidata":"https://www.wikidata.org/wiki/Q6882374","display_name":"Mitral valve repair","level":3,"score":0.45045050978660583},{"id":"https://openalex.org/C2777543888","wikidata":"https://www.wikidata.org/wiki/Q369939","display_name":"Mitral valve","level":2,"score":0.38903436064720154}],"mesh":[{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008945","descriptor_name":"Mitral Valve Prolapse","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D008945","descriptor_name":"Mitral Valve Prolapse","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D008945","descriptor_name":"Mitral Valve Prolapse","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc53108.2024.10781640","doi":"https://doi.org/10.1109/embc53108.2024.10781640","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc53108.2024.10781640","pdf_url":null,"source":{"id":"https://openalex.org/S4363608786","display_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","issn_l":"2375-7477","issn":["2375-7477"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["doyens","jufo-1","ki-jl-1","medline","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:40039921","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40039921","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1968464116","https://openalex.org/W2024161897","https://openalex.org/W2026221609","https://openalex.org/W2066168972","https://openalex.org/W2103247923","https://openalex.org/W2155516175","https://openalex.org/W2281274790","https://openalex.org/W2309990757","https://openalex.org/W2323812521","https://openalex.org/W2340972685","https://openalex.org/W3127436338","https://openalex.org/W3173315732","https://openalex.org/W3195181669","https://openalex.org/W4220965910","https://openalex.org/W4248741030","https://openalex.org/W4393560722","https://openalex.org/W4402080885"],"related_works":["https://openalex.org/W4380715106","https://openalex.org/W3014451409","https://openalex.org/W4411604916","https://openalex.org/W4295215085","https://openalex.org/W2018942998","https://openalex.org/W2419284128","https://openalex.org/W4406528535","https://openalex.org/W2021888571","https://openalex.org/W7223340342","https://openalex.org/W3108959786"],"abstract_inverted_index":{"Mitral":[0],"valve":[1,29,45,50],"prolapse":[2],"(MVP),":[3],"affecting":[4],"around":[5],"2-3":[6],"percent":[7],"of":[8,27,61,143,179],"the":[9,13,24,35,54,59,115,141,146],"adult":[10],"population":[11],"in":[12,32,114,124,128,140,182],"United":[14],"States,":[15],"is":[16,53,76],"a":[17,88,138],"common":[18],"valvular":[19],"heart":[20],"disease":[21],"marked":[22],"by":[23],"impaired":[25],"closure":[26],"mitral":[28,44,49],"leaflets,":[30],"resulting":[31],"regurgitation":[33],"when":[34],"left":[36],"ventricle":[37],"(LV)":[38],"contracts.":[39],"While":[40],"surgical":[41],"treatment,":[42],"including":[43],"repair":[46],"(MVRe)":[47],"or":[48],"replacement":[51],"(MVRp),":[52],"only":[55],"definitive":[56],"intervention,":[57],"understanding":[58],"impact":[60],"these":[62],"procedures":[63],"on":[64],"LV":[65,73,125,147,154,168],"hemodynamics,":[66],"especially":[67],"regarding":[68],"diastolic":[69,169],"filling":[70],"vortices":[71,144],"and":[72,133,145,158,164,170],"pumping":[74],"efficiency,":[75],"crucial":[77],"for":[78,176],"evaluating":[79],"post-surgery":[80],"cardiac":[81,96],"remodeling.":[82],"In":[83],"this":[84,119],"study,":[85],"we":[86],"utilized":[87],"recently":[89],"developed":[90],"pipeline":[91,120],"that":[92],"combines":[93],"standard":[94],"cine":[95],"magnetic":[97,103],"resonance":[98,104],"imaging":[99,105],"(CMR)":[100],"with":[101],"phase-contrast":[102],"(PC-MRI)":[106],"data":[107],"to":[108,121,167],"model":[109],"patientspecific":[110],"fluid-structure":[111],"interaction":[112],"(FSI)":[113],"LV.":[116],"We":[117],"used":[118],"examine":[122],"alterations":[123],"flow":[126],"patterns":[127],"one":[129],"MVP":[130],"patient":[131],"before":[132],"after":[134],"MVRe.":[135],"Findings":[136],"indicate":[137],"reduction":[139],"number":[142],"volumetric":[148],"kinetic":[149],"energy":[150],"changes":[151],"post-MVRe.":[152],"Studying":[153],"hemodynamic":[155],"characteristics":[156],"pre-":[157],"post-MVRe,":[159],"obtained":[160],"from":[161],"FSI":[162],"modeling,":[163],"their":[165],"relationship":[166],"systolic":[171],"functional":[172],"indices":[173],"holds":[174],"promise":[175],"improved":[177],"design":[178],"MV":[180],"surgery":[181],"MVP.":[183]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2024-12-18T00:00:00"}