{"id":"https://openalex.org/W4405355646","doi":"https://doi.org/10.1016/j.xrrt.2024.11.004","title":"Efficacy and safety of xenograft augmentation in rotator cuff repair: a systematic review and meta-analysis","display_name":"Efficacy and safety of xenograft augmentation in rotator cuff repair: a systematic review and meta-analysis","publication_year":2024,"publication_date":"2024-12-13","ids":{"openalex":"https://openalex.org/W4405355646","doi":"https://doi.org/10.1016/j.xrrt.2024.11.004","pmid":"https://pubmed.ncbi.nlm.nih.gov/40321878","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12047598"},"language":"en","primary_location":{"id":"doi:10.1016/j.xrrt.2024.11.004","doi":"https://doi.org/10.1016/j.xrrt.2024.11.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.xrrt.2024.11.004","pdf_url":"https://jsesreviewsreportstech.org/article/S2666-6391(24)00151-2/pdf","source":{"id":"https://openalex.org/S4210219462","display_name":"JSES Reviews Reports and Techniques","issn_l":"2666-6391","issn":["2666-6391"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JSES Reviews, Reports, and Techniques","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://jsesreviewsreportstech.org/article/S2666-6391(24)00151-2/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5093677354","display_name":"Felix Conrad Oettl","orcid":"https://orcid.org/0000-0001-9721-685X","observed_orcids":["https://orcid.org/0000-0001-9721-685X"]},"institutions":[{"id":"https://openalex.org/I1281539108","display_name":"Hospital for Special Surgery","ror":"https://ror.org/03zjqec80","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1281539108"]},{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]},{"id":"https://openalex.org/I4210124057","display_name":"Universit\u00e4tsklinik Balgrist","ror":"https://ror.org/02yzaka98","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210124057"]}],"countries":["CH","US"],"is_corresponding":true,"raw_author_name":"Felix C. Oettl","raw_affiliation_strings":["Department of Orthopedic Surgery, Balgrist University Hospital, University of Zurich, Zurich, Switzerland","Hospital for Special Surgery, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0001-9721-685X","affiliations":[{"raw_affiliation_string":"Department of Orthopedic Surgery, Balgrist University Hospital, University of Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I202697423","https://openalex.org/I4210124057"]},{"raw_affiliation_string":"Hospital for Special Surgery, New York, NY, USA","institution_ids":["https://openalex.org/I1281539108"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093820284","display_name":"Tim Ludwig T\u00fcngler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1281539108","display_name":"Hospital for Special Surgery","ror":"https://ror.org/03zjqec80","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1281539108"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tim Tuengler","raw_affiliation_strings":["Hospital for Special Surgery, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital for Special Surgery, New York, NY, USA","institution_ids":["https://openalex.org/I1281539108"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052778046","display_name":"Moritz Kraus","orcid":"https://orcid.org/0000-0002-6488-1009","observed_orcids":["https://orcid.org/0000-0002-6488-1009"]},"institutions":[{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]},{"id":"https://openalex.org/I4210100468","display_name":"University Hospital Zurich","ror":"https://ror.org/01462r250","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210100468"]},{"id":"https://openalex.org/I4210112317","display_name":"Schulthess-Klinik","ror":"https://ror.org/01xm3qq33","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210112317"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Moritz Kraus","raw_affiliation_strings":["Department of Trauma, University Hospital Zurich, University of Zurich, Zurich, Switzerland","Schulthess Klink, Zurich, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-6488-1009","affiliations":[{"raw_affiliation_string":"Department of Trauma, University Hospital Zurich, University of Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I202697423","https://openalex.org/I4210100468"]},{"raw_affiliation_string":"Schulthess Klink, Zurich, Switzerland","institution_ids":["https://openalex.org/I4210112317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090462539","display_name":"Mert Marcel Dagli","orcid":"https://orcid.org/0000-0002-5201-6720","observed_orcids":["https://orcid.org/0000-0002-5201-6720"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mert M. Dagli","raw_affiliation_strings":["Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029898779","display_name":"Paul M. Inclan","orcid":"https://orcid.org/0000-0003-0819-0446","observed_orcids":["https://orcid.org/0000-0003-0819-0446"]},"institutions":[{"id":"https://openalex.org/I1281539108","display_name":"Hospital for Special Surgery","ror":"https://ror.org/03zjqec80","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1281539108"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul Inclan","raw_affiliation_strings":["Hospital for Special Surgery, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital for Special Surgery, New York, NY, USA","institution_ids":["https://openalex.org/I1281539108"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063311766","display_name":"Scott Alan Rodeo","orcid":"https://orcid.org/0000-0002-0745-9880","observed_orcids":["https://orcid.org/0000-0002-0745-9880"]},"institutions":[{"id":"https://openalex.org/I1281539108","display_name":"Hospital for Special Surgery","ror":"https://ror.org/03zjqec80","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1281539108"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Scott A. Rodeo","raw_affiliation_strings":["Hospital for Special Surgery, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital for Special Surgery, New York, NY, USA","institution_ids":["https://openalex.org/I1281539108"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5063311766","https://openalex.org/A5093677354"],"corresponding_institution_ids":["https://openalex.org/I1281539108","https://openalex.org/I202697423","https://openalex.org/I4210124057"],"apc_list":{"value":1250,"currency":"USD","value_usd":1250},"apc_paid":{"value":1250,"currency":"USD","value_usd":1250},"fwci":0.4085,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.43445393,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"5","issue":"2","first_page":"222","last_page":"230"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10280","display_name":"Shoulder Injury and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10280","display_name":"Shoulder Injury and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10630","display_name":"Orthopedic Surgery and Rehabilitation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11068","display_name":"Tendon Structure and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rotator-cuff-repair","display_name":"rotator cuff repair","score":0.9179999828338623},{"id":"https://openalex.org/keywords/rotator-cuff-tear","display_name":"rotator cuff tear","score":0.9520000219345093},{"id":"https://openalex.org/keywords/radiological-healing","display_name":"radiological healing","score":0.621999979019165},{"id":"https://openalex.org/keywords/repair-failure","display_name":"repair failure","score":0.7350000143051147},{"id":"https://openalex.org/keywords/postoperative-complications","display_name":"postoperative complications","score":0.8389999866485596},{"id":"https://openalex.org/keywords/shoulder-range-of-motion","display_name":"shoulder range of motion","score":0.7429999709129333},{"id":"https://openalex.org/keywords/tendon-strength","display_name":"tendon strength","score":0.335999995470047}],"concepts":[{"id":"https://openalex.org/C2776511800","wikidata":"https://www.wikidata.org/wiki/Q1764136","display_name":"Rotator cuff","level":2,"score":0.8059396147727966},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.6671087145805359},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5638670325279236},{"id":"https://openalex.org/C189708586","wikidata":"https://www.wikidata.org/wiki/Q1504425","display_name":"Systematic review","level":3,"score":0.4461826980113983},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.32901033759117126},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.24865570664405823},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1924140751361847},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.11595365405082703},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1016/j.xrrt.2024.11.004","doi":"https://doi.org/10.1016/j.xrrt.2024.11.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.xrrt.2024.11.004","pdf_url":"https://jsesreviewsreportstech.org/article/S2666-6391(24)00151-2/pdf","source":{"id":"https://openalex.org/S4210219462","display_name":"JSES Reviews Reports and Techniques","issn_l":"2666-6391","issn":["2666-6391"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JSES Reviews, Reports, and Techniques","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12047598","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12047598","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12047598/pdf/main.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JSES Rev Rep Tech","raw_type":"Text"},{"id":"pmid:40321878","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40321878","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JSES reviews, reports, and techniques","raw_type":"Journal Article"},{"id":"pmh:oai:www.zora.uzh.ch:277637","doi":null,"is_oa":true,"landing_page_url":"https://www.zora.uzh.ch/id/eprint/277637/1/2024_Oettl_JSES_Rev_Rep_Tech_Efficacy_and_safety_of_xenograft_augmentation.pdf","pdf_url":"https://www.zora.uzh.ch/id/eprint/277637/1/2024_Oettl_JSES_Rev_Rep_Tech_Efficacy_and_safety_of_xenograft_augmentation.pdf","source":{"id":"https://openalex.org/S4306401281","display_name":"Zurich Open Repository and Archive (University of Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I202697423","host_organization_name":"University of Zurich","host_organization_lineage":["https://openalex.org/I202697423"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Oettl, Felix C; Tuengler, Tim; Kraus, Moritz; Dagli, Mert M; Inclan, Paul; Rodeo, Scott A (2025). Efficacy and safety of xenograft augmentation in rotator cuff repair: a systematic review and meta-analysis. JSES Reviews, Reports, and Techniques, 5(2):222-230.","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:www.zora.uzh.ch:20.500.14742/230661","doi":null,"is_oa":true,"landing_page_url":"https://www.zora.uzh.ch/handle/20.500.14742/230661","pdf_url":null,"source":{"id":"https://openalex.org/S4306401281","display_name":"Zurich Open Repository and Archive (University of Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I202697423","host_organization_name":"University of Zurich","host_organization_lineage":["https://openalex.org/I202697423"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Oettl, F. C., Tuengler, T., Kraus, M., Dagli, M. M., Inclan, P., & Rodeo, S. A. (2025). Efficacy and safety of xenograft augmentation in rotator cuff repair: a systematic review and meta-analysis. JSES Reviews, Reports, and Techniques, 5, 222\u2013230. https://doi.org/10.1016/j.xrrt.2024.11.004","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.xrrt.2024.11.004","doi":"https://doi.org/10.1016/j.xrrt.2024.11.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.xrrt.2024.11.004","pdf_url":"https://jsesreviewsreportstech.org/article/S2666-6391(24)00151-2/pdf","source":{"id":"https://openalex.org/S4210219462","display_name":"JSES Reviews Reports and Techniques","issn_l":"2666-6391","issn":["2666-6391"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JSES Reviews, Reports, and Techniques","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320332513","display_name":"Weill Cornell Medical College","ror":"https://ror.org/02r109517"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4405355646.pdf","grobid_xml":"https://content.openalex.org/works/W4405355646.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W183527674","https://openalex.org/W1972635516","https://openalex.org/W1997944826","https://openalex.org/W2010937757","https://openalex.org/W2041812845","https://openalex.org/W2051822069","https://openalex.org/W2052848582","https://openalex.org/W2077553246","https://openalex.org/W2114386408","https://openalex.org/W2117354930","https://openalex.org/W2135739558","https://openalex.org/W2137147154","https://openalex.org/W2140174911","https://openalex.org/W2154541870","https://openalex.org/W2166087914","https://openalex.org/W2508665864","https://openalex.org/W2531269403","https://openalex.org/W2745449196","https://openalex.org/W2751384418","https://openalex.org/W2769634407","https://openalex.org/W2807944888","https://openalex.org/W2810606563","https://openalex.org/W2903597418","https://openalex.org/W2948013618","https://openalex.org/W2970684805","https://openalex.org/W2974793780","https://openalex.org/W3005739032","https://openalex.org/W3011725608","https://openalex.org/W3011784267","https://openalex.org/W3018507196","https://openalex.org/W3082114842","https://openalex.org/W3124119190","https://openalex.org/W3135800537","https://openalex.org/W3186824348","https://openalex.org/W3206279002","https://openalex.org/W3213716721","https://openalex.org/W4213437622","https://openalex.org/W4283817755","https://openalex.org/W6767567325"],"related_works":["https://openalex.org/W2343343909","https://openalex.org/W2782101955","https://openalex.org/W7097680724","https://openalex.org/W2523602798","https://openalex.org/W2513050262","https://openalex.org/W1987649349","https://openalex.org/W2133571012","https://openalex.org/W2296302684","https://openalex.org/W2346726204","https://openalex.org/W4383849270"],"abstract_inverted_index":{"Rotator":[0],"cuff":[1,60,97,278],"tears":[2,279],"are":[3,32,322,333],"common":[4,23],"disorders":[5],"that":[6,91,109,306],"can":[7],"significantly":[8,282],"impact":[9],"patient\u015b":[10],"shoulder":[11],"function":[12],"and":[13,42,50,79,105,113,133,158,171,180,199,270,339,358,361],"quality":[14],"of":[15,26,37,57,81,118,126,136,186,272,276,350],"life.":[16],"Incomplete":[17],"or":[18],"failed":[19],"healing":[20,225,285],"is":[21,296],"relatively":[22],"following":[24],"repair":[25,61,66,201,275,320],"large":[27],"tendon":[28,357],"tears.":[29],"Xenograft":[30],"materials":[31,94,309],"increasingly":[33],"used":[34],"for":[35,131,139,143,231,313],"augmentation":[36],"repairs,":[38],"but":[39],"their":[40,316],"efficacy":[41],"safety":[43],"remain":[44],"under":[45],"debate.":[46],"This":[47],"systematic":[48],"review":[49],"meta-analysis":[51],"aimed":[52],"to":[53,64,153,291,335,340],"evaluate":[54],"the":[55,123,134,165,223,348],"outcomes":[56],"xenograft-augmented":[58,198],"rotator":[59,96,277],"in":[62,95,194,267],"comparison":[63],"standard":[65,200,292],"techniques.":[67],"A":[68],"detailed":[69],"literature":[70],"search":[71],"was":[72,120,148,245],"conducted":[73],"across":[74],"PubMed,":[75],"Embase,":[76],"Cochrane":[77,124],"Library,":[78],"Web":[80],"Science":[82],"databases":[83],"on":[84,89,111,364],"September":[85],"2,":[86],"2023,":[87],"focusing":[88],"studies":[90,107,163],"utilized":[92],"xenograft":[93,175,232,243,308,343],"repair.":[98,293],"We":[99],"included":[100],"randomized":[101],"controlled":[102],"trials":[103],"(RCTs)":[104],"cohort":[106],"(CHS)":[108],"reported":[110],"dichotomous":[112],"continuous":[114],"outcome":[115],"measures.":[116],"Risk":[117,125,135],"bias":[119],"assessed":[121],"using":[122,150],"Bias":[127,137],"tool":[128,142],"2":[129],"(RoB2)":[130],"RCTs":[132,170,332],"assessment":[138],"non-RCT":[140],"studies-I":[141],"nonrandomized":[144],"studies.":[145],"Data":[146],"synthesis":[147],"performed":[149],"random-effects":[151],"models":[152],"compute":[154],"odds":[155],"ratios":[156],"(ORs)":[157],"standardized":[159],"mean":[160],"differences.":[161],"Eight":[162],"met":[164],"inclusion":[166],"criteria,":[167],"including":[168,177],"three":[169],"five":[172],"CHS":[173,213],"evaluating":[174],"materials,":[176],"porcine":[178],"dermis":[179],"small":[181],"intestine":[182],"submucosa":[183],"patches.":[184],"Meta-analysis":[185],"RCT":[187],"data":[188],"revealed":[189],"no":[190,228],"statistically":[191,249],"significant":[192,229,250,263],"difference":[193],"failure":[195,288],"rates":[196,226,289],"between":[197],"groups":[202],"(OR":[203,214,234,254],"0.48,":[204],"95%":[205,216,236,256],"CI":[206,217,237,257],"0.08-2.90;":[207],"P":[208,219,239,259],"=":[209,220,240,260],".42),":[210],"as":[211,345,347,354],"did":[212],"1.08,":[215],"0.49-2.38;":[218],".85).":[221],"Similarly,":[222],"radiological":[224,284],"showed":[227],"benefit":[230],"use":[233,244],"1.41,":[235],"0.23-8.56;":[238],".71).":[241],"However,":[242,294],"associated":[246,297],"with":[247,298],"a":[248,299],"higher":[251,300],"complication":[252,301],"rate":[253],"3.65,":[255],"1.28-10.4;":[258],".02).":[261],"No":[262],"differences":[264],"were":[265],"observed":[266],"strength":[268],"measurements":[269],"range":[271],"motion.":[273],"Xenograft-augmented":[274],"does":[280],"not":[281,323],"improve":[283],"nor":[286],"reduce":[287],"compared":[290],"it":[295],"rate.":[302],"These":[303],"findings":[304],"suggest":[305],"while":[307],"may":[310],"be":[311],"safe":[312],"clinical":[314],"use,":[315],"benefits":[317],"over":[318],"traditional":[319],"techniques":[321],"conclusively":[324],"supported":[325],"by":[326],"current":[327],"evidence.":[328],"Further":[329],"high-quality,":[330],"multicenter":[331],"needed":[334],"confirm":[336],"these":[337],"results":[338],"explore":[341],"alternative":[342],"implants":[344],"well":[346],"role":[349],"patient-intrinsic":[351],"factors,":[352],"such":[353],"tear":[355],"size,":[356],"muscle":[359],"quality,":[360],"medical":[362],"comorbidities":[363],"outcome.":[365]},"counts_by_year":[{"year":2026,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-12-14T00:00:00"}