{"id":"https://openalex.org/W4405221663","doi":"https://doi.org/10.1093/jsxmed/qdae167.109","title":"(111) PROSTATE SPECIFIC ANTIGEN LEVELS IN TRANSGENDER WOMEN ARE LOWER THAN CISGENDER MEN","display_name":"(111) PROSTATE SPECIFIC ANTIGEN LEVELS IN TRANSGENDER WOMEN ARE LOWER THAN CISGENDER MEN","publication_year":2024,"publication_date":"2024-08-12","ids":{"openalex":"https://openalex.org/W4405221663","doi":"https://doi.org/10.1093/jsxmed/qdae167.109"},"language":"en","primary_location":{"id":"doi:10.1093/jsxmed/qdae167.109","doi":"https://doi.org/10.1093/jsxmed/qdae167.109","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jsxmed/qdae167.109","pdf_url":null,"source":{"id":"https://openalex.org/S159512450","display_name":"The Journal of Sexual Medicine","issn_l":"1743-6095","issn":["1743-6095","1743-6109"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Sexual Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"V Nguyen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800935791","display_name":"UC San Diego Health System","ror":"https://ror.org/01kbfgm16","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800935791","https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"V Nguyen","raw_affiliation_strings":["UC San Diego Health"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UC San Diego Health","institution_ids":["https://openalex.org/I2800935791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057623032","display_name":"Sheldon Morris","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800935791","display_name":"UC San Diego Health System","ror":"https://ror.org/01kbfgm16","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800935791","https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S Morris","raw_affiliation_strings":["UC San Diego Health"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UC San Diego Health","institution_ids":["https://openalex.org/I2800935791"]}]},{"author_position":"middle","author":{"id":null,"display_name":"M Meagher","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M Meagher","raw_affiliation_strings":["UC San Diego"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UC San Diego","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":null,"display_name":"L Burke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800935791","display_name":"UC San Diego Health System","ror":"https://ror.org/01kbfgm16","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800935791","https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L Burke","raw_affiliation_strings":["UC San Diego Health"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UC San Diego Health","institution_ids":["https://openalex.org/I2800935791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036003731","display_name":"Stephen J. Freedland","orcid":"https://orcid.org/0000-0002-8104-6419","observed_orcids":["https://orcid.org/0000-0002-8104-6419"]},"institutions":[{"id":"https://openalex.org/I1282927834","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S Freedland","raw_affiliation_strings":["Cedars-Sinai Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cedars-Sinai Medical Center","institution_ids":["https://openalex.org/I1282927834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081777896","display_name":"Farnoosh Nik\u2010Ahd","orcid":"https://orcid.org/0000-0003-4726-9894","observed_orcids":["https://orcid.org/0000-0003-4726-9894"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"F Nik-Ahd","raw_affiliation_strings":["UC San Francisco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UC San Francisco","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044071754","display_name":"Brent Shane Rose","orcid":"https://orcid.org/0000-0002-3197-9552","observed_orcids":["https://orcid.org/0000-0002-3197-9552"]},"institutions":[{"id":"https://openalex.org/I2800935791","display_name":"UC San Diego Health System","ror":"https://ror.org/01kbfgm16","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800935791","https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B Rose","raw_affiliation_strings":["UC San Diego Health"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UC San Diego Health","institution_ids":["https://openalex.org/I2800935791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090503789","display_name":"Devin N Patel","orcid":"https://orcid.org/0000-0002-9764-5870","observed_orcids":["https://orcid.org/0000-0002-9764-5870"]},"institutions":[{"id":"https://openalex.org/I2800935791","display_name":"UC San Diego Health System","ror":"https://ror.org/01kbfgm16","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800935791","https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D Patel","raw_affiliation_strings":["UC San Diego Health"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UC San Diego Health","institution_ids":["https://openalex.org/I2800935791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040802277","display_name":"Amirali Salmasi","orcid":"https://orcid.org/0000-0002-3884-6322","observed_orcids":["https://orcid.org/0000-0002-3884-6322"]},"institutions":[{"id":"https://openalex.org/I2800935791","display_name":"UC San Diego Health System","ror":"https://ror.org/01kbfgm16","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800935791","https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A Salmasi","raw_affiliation_strings":["UC San Diego Health"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UC San Diego Health","institution_ids":["https://openalex.org/I2800935791"]}]},{"author_position":"middle","author":{"id":null,"display_name":"J Anger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800935791","display_name":"UC San Diego Health System","ror":"https://ror.org/01kbfgm16","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800935791","https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J Anger","raw_affiliation_strings":["UC San Diego Health"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UC San Diego Health","institution_ids":["https://openalex.org/I2800935791"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032641888","display_name":"Christina  A. M. Jamieson","orcid":"https://orcid.org/0000-0001-5328-2628","observed_orcids":["https://orcid.org/0000-0001-5328-2628"]},"institutions":[{"id":"https://openalex.org/I2800935791","display_name":"UC San Diego Health System","ror":"https://ror.org/01kbfgm16","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800935791","https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C Jamieson","raw_affiliation_strings":["UC San Diego Health"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UC San Diego Health","institution_ids":["https://openalex.org/I2800935791"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3728,"currency":"USD","value_usd":3728},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.34149349,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"21","issue":"Supplement_7","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.6147000193595886,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.6147000193595886,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10156","display_name":"LGBTQ Health, Identity, and Policy","score":0.219200000166893,"subfield":{"id":"https://openalex.org/subfields/3207","display_name":"Social Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.06909999996423721,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-specific-antigen","display_name":"prostate-specific antigen","score":0.9700000286102295},{"id":"https://openalex.org/keywords/transgender-women","display_name":"transgender women","score":0.9580000042915344},{"id":"https://openalex.org/keywords/non-binary-people","display_name":"non-binary people","score":0.8970000147819519},{"id":"https://openalex.org/keywords/prostate-cancer-screening","display_name":"prostate cancer screening","score":0.777999997138977},{"id":"https://openalex.org/keywords/gender-affirming-hormone-therapy","display_name":"gender-affirming hormone therapy","score":0.906000018119812},{"id":"https://openalex.org/keywords/testosterone","display_name":"testosterone","score":0.9010000228881836},{"id":"https://openalex.org/keywords/estradiol","display_name":"estradiol","score":0.9919999837875366},{"id":"https://openalex.org/keywords/antiandrogen-therapy","display_name":"antiandrogen therapy","score":0.8610000014305115},{"id":"https://openalex.org/keywords/hormone-dependent-cancers","display_name":"hormone-dependent tumors","score":0.6970000267028809}],"concepts":[{"id":"https://openalex.org/C2779671885","wikidata":"https://www.wikidata.org/wiki/Q189125","display_name":"Transgender","level":2,"score":0.7716386914253235},{"id":"https://openalex.org/C2781406297","wikidata":"https://www.wikidata.org/wiki/Q409450","display_name":"Prostate-specific antigen","level":4,"score":0.6831620931625366},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4657128155231476},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3601788878440857},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.35582998394966125},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.3437308073043823},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.3404971957206726},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.30801278352737427},{"id":"https://openalex.org/C11171543","wikidata":"https://www.wikidata.org/wiki/Q41630","display_name":"Psychoanalysis","level":1,"score":0.0744900107383728},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1093/jsxmed/qdae167.109","doi":"https://doi.org/10.1093/jsxmed/qdae167.109","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jsxmed/qdae167.109","pdf_url":null,"source":{"id":"https://openalex.org/S159512450","display_name":"The Journal of Sexual Medicine","issn_l":"1743-6095","issn":["1743-6095","1743-6109"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Sexual Medicine","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3206807531","https://openalex.org/W338913515","https://openalex.org/W3014514787","https://openalex.org/W2903083518","https://openalex.org/W4286375426","https://openalex.org/W2920793196","https://openalex.org/W4255120256","https://openalex.org/W2031954916","https://openalex.org/W846826746","https://openalex.org/W2381163510"],"abstract_inverted_index":{"Abstract":[0],"Introduction":[1],"Little":[2],"is":[3,248,260],"known":[4],"about":[5],"incidence":[6],"and":[7,18,43,110,113,134,171,199,254],"screening":[8,273],"patterns":[9],"of":[10,47,81,115,176,204,225,252,256],"prostate":[11,31,271],"cancer,":[12],"a":[13,77,91,243,249],"hormone-sensitive":[14],"malignancy,":[15],"among":[16,235],"transgender":[17],"nonbinary":[19],"(TGNB)":[20],"individuals":[21,57,123,153,209,237],"assigned":[22,102,238],"male":[23,239],"at":[24,70,103,240],"birth.":[25],"Objective":[26],"We":[27,53,74,119],"sought":[28],"to":[29,40,44,269],"evaluate":[30],"specific":[32],"antigen":[33],"(PSA)":[34],"levels":[35,186,232],"in":[36,151,182,194,207,275],"this":[37,161,276],"population":[38],"compared":[39],"cisgender":[41,82,136],"men":[42,83,137],"investigate":[45],"effect":[46],"gender":[48,105,257],"affirming":[49,258],"hormonal":[50],"therapy.":[51,117],"Methods":[52],"identified":[54,120],"TGNB":[55,122,152,208,236],"HIV-negative":[56],"age":[58,84,125,139,167],">":[59,85],"40":[60,86],"from":[61],"the":[62,221],"California":[63],"Collaborative":[64],"Treatment":[65],"Group":[66],"603":[67],"study":[68],"aimed":[69],"evaluating":[71],"pre-exposure":[72],"prophylaxis.":[73],"then":[75],"assembled":[76],"3:1":[78],"comparison":[79],"group":[80],"followed":[87],"by":[88,166],"Urology":[89],"for":[90],"diagnosis":[92],"other":[93],"than":[94],"elevated":[95],"PSA.":[96,264],"Data":[97],"abstracted":[98],"included":[99],"age,":[100],"sex":[101],"birth,":[104],"identity,":[106],"race/ethnicity,":[107],"PSA,":[108],"testosterone":[109,172,218],"estradiol":[111],"levels,":[112],"use":[114,255],"hormone":[116],"Results":[118],"31":[121],"(median":[124,138],"47":[126],"years,":[127,141],"77%":[128],"on":[129,132,143],"estrogen,":[130],"48%":[131],"antiandrogen)":[133],"94":[135],"57":[140],"25%":[142],"testosterone;":[144],"Table":[145,213],"1).":[146],"PSA":[147,178,190,206,226,231,253],"was":[148],"significantly":[149,187],"lower":[150,234,263],"(0.23":[154],"vs":[155],"0.93":[156],"ng/ml,":[157],"p":[158],"<":[159,180,192,211,228],"0.01);":[160],"remained":[162,220],"true":[163],"after":[164],"stratifying":[165],"(Table":[168],"2).":[169],"Age":[170],"were":[173,202],"significant":[174,223],"predictors":[175,203],"increased":[177],"(p":[179,191,210,227],"0.01)":[181,193],"both":[183,195],"cohorts.":[184],"Estradiol":[185],"predicted":[188],"decreased":[189,205],"cohorts,":[196],"whereas":[197],"antiandrogen":[198],"estrogen":[200],"therapy":[201],"0.01,":[212],"3).":[214],"On":[215],"multivariate":[216],"analysis,":[217],"level":[219,247],"only":[222],"predictor":[224],"0.01).":[229],"Conclusions":[230],"are":[233,267],"birth":[241],"with":[242,262],"retained":[244],"prostate.":[245],"Testosterone":[246],"key":[250],"determinant":[251],"hormones":[259],"associated":[261],"Further":[265],"studies":[266],"needed":[268],"establish":[270],"cancer":[272],"cutoffs":[274],"population.":[277],"Disclosure":[278],"No.":[279]},"counts_by_year":[],"updated_date":"2026-10-08T09:06:37.294493","created_date":"2025-10-10T00:00:00"}