{"id":"https://openalex.org/W4405134615","doi":"https://doi.org/10.1016/j.annonc.2024.10.476","title":"453P Cross-resistance of head and neck squamous cell cancer cells to cetuximab and radiation","display_name":"453P Cross-resistance of head and neck squamous cell cancer cells to cetuximab and radiation","publication_year":2024,"publication_date":"2024-12-01","ids":{"openalex":"https://openalex.org/W4405134615","doi":"https://doi.org/10.1016/j.annonc.2024.10.476"},"language":"en","primary_location":{"id":"doi:10.1016/j.annonc.2024.10.476","doi":"https://doi.org/10.1016/j.annonc.2024.10.476","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.annonc.2024.10.476","pdf_url":"https://www.annalsofoncology.org/article/S0923-7534(24)04532-0/pdf","source":{"id":"https://openalex.org/S41454044","display_name":"Annals of Oncology","issn_l":"0923-7534","issn":["0923-7534","1569-8041"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Oncology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.annalsofoncology.org/article/S0923-7534(24)04532-0/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013854802","display_name":"James A. Bonner","orcid":"https://orcid.org/0000-0002-8413-3788","observed_orcids":["https://orcid.org/0000-0002-8413-3788"]},"institutions":[{"id":"https://openalex.org/I1335695989","display_name":"University of Alabama at Birmingham Hospital","ror":"https://ror.org/01rm42p40","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1335695989","https://openalex.org/I320755355"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.A. Bonner","raw_affiliation_strings":["Radiation Oncology, University of Alabama at Birmingham Hospital, Birmingham, AL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiation Oncology, University of Alabama at Birmingham Hospital, Birmingham, AL, USA","institution_ids":["https://openalex.org/I1335695989"]}]},{"author_position":"middle","author":{"id":null,"display_name":"C. Xing","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335695989","display_name":"University of Alabama at Birmingham Hospital","ror":"https://ror.org/01rm42p40","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1335695989","https://openalex.org/I320755355"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Xing","raw_affiliation_strings":["Radiation Oncology, University of Alabama at Birmingham Hospital, Birmingham, AL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiation Oncology, University of Alabama at Birmingham Hospital, Birmingham, AL, USA","institution_ids":["https://openalex.org/I1335695989"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069015500","display_name":"Hoa Quang Trummell","orcid":"https://orcid.org/0000-0003-1343-7378","observed_orcids":["https://orcid.org/0000-0003-1343-7378"]},"institutions":[{"id":"https://openalex.org/I1335695989","display_name":"University of Alabama at Birmingham Hospital","ror":"https://ror.org/01rm42p40","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1335695989","https://openalex.org/I320755355"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. Trummell","raw_affiliation_strings":["Radiation Oncology, University of Alabama at Birmingham Hospital, Birmingham, AL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiation Oncology, University of Alabama at Birmingham Hospital, Birmingham, AL, USA","institution_ids":["https://openalex.org/I1335695989"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1335695989"],"apc_list":{"value":4600,"currency":"USD","value_usd":4600},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.35001632,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"35","issue":null,"first_page":"S1571","last_page":"S1571"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10755","display_name":"HER2/EGFR in Cancer Research","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10668","display_name":"Endometrial and Cervical Cancer Treatments","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cross-resistance","display_name":"cross-resistance","score":0.7979999780654907},{"id":"https://openalex.org/keywords/head-and-neck-squamous-cell-carcinoma","display_name":"head and neck squamous cell carcinoma","score":0.9440000057220459},{"id":"https://openalex.org/keywords/cetuximab","display_name":"cetuximab","score":1.0},{"id":"https://openalex.org/keywords/radioresistance-biology","display_name":"radioresistance (biology)","score":0.7860000133514404},{"id":"https://openalex.org/keywords/egfr-inhibitors","display_name":"EGFR inhibitors","score":0.7599999904632568},{"id":"https://openalex.org/keywords/treatment-resistance-mechanisms","display_name":"treatment resistance mechanisms","score":0.6380000114440918}],"concepts":[{"id":"https://openalex.org/C2779998722","wikidata":"https://www.wikidata.org/wiki/Q420296","display_name":"Cetuximab","level":4,"score":0.9685149192810059},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9370723366737366},{"id":"https://openalex.org/C3019814559","wikidata":"https://www.wikidata.org/wiki/Q681817","display_name":"Squamous cell cancer","level":3,"score":0.7316628694534302},{"id":"https://openalex.org/C3018411727","wikidata":"https://www.wikidata.org/wiki/Q3867488","display_name":"Head and neck","level":2,"score":0.6880489587783813},{"id":"https://openalex.org/C2776530083","wikidata":"https://www.wikidata.org/wiki/Q1783924","display_name":"Head and neck cancer","level":3,"score":0.6217362880706787},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5689367651939392},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5458391904830933},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.44319581985473633},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.34322476387023926},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.10462266206741333},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.0622425377368927}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.annonc.2024.10.476","doi":"https://doi.org/10.1016/j.annonc.2024.10.476","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.annonc.2024.10.476","pdf_url":"https://www.annalsofoncology.org/article/S0923-7534(24)04532-0/pdf","source":{"id":"https://openalex.org/S41454044","display_name":"Annals of Oncology","issn_l":"0923-7534","issn":["0923-7534","1569-8041"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Oncology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.annonc.2024.10.476","doi":"https://doi.org/10.1016/j.annonc.2024.10.476","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.annonc.2024.10.476","pdf_url":"https://www.annalsofoncology.org/article/S0923-7534(24)04532-0/pdf","source":{"id":"https://openalex.org/S41454044","display_name":"Annals of Oncology","issn_l":"0923-7534","issn":["0923-7534","1569-8041"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Oncology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4405134615.pdf","grobid_xml":"https://content.openalex.org/works/W4405134615.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4389280681","https://openalex.org/W4230968873","https://openalex.org/W2067624522","https://openalex.org/W2491737197","https://openalex.org/W2329844376","https://openalex.org/W1546910921","https://openalex.org/W3092413872","https://openalex.org/W2092946571","https://openalex.org/W2552944761","https://openalex.org/W2407162565"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2024-12-08T00:00:00"}