{"id":"https://openalex.org/W4405069442","doi":"https://doi.org/10.1016/j.stem.2024.11.002","title":"Human adult neurogenesis loss corresponds with cognitive decline during epilepsy progression","display_name":"Human adult neurogenesis loss corresponds with cognitive decline during epilepsy progression","publication_year":2024,"publication_date":"2024-12-05","ids":{"openalex":"https://openalex.org/W4405069442","doi":"https://doi.org/10.1016/j.stem.2024.11.002","pmid":"https://pubmed.ncbi.nlm.nih.gov/39642885","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12807443"},"language":"en","primary_location":{"id":"doi:10.1016/j.stem.2024.11.002","doi":"https://doi.org/10.1016/j.stem.2024.11.002","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.stem.2024.11.002","pdf_url":null,"source":{"id":"https://openalex.org/S128124174","display_name":"Cell stem cell","issn_l":"1875-9777","issn":["1875-9777","1934-5909"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Stem Cell","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.stem.2024.11.002","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004772740","display_name":"Aswathy Ammothumkandy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210150380","display_name":"Broad Center","ror":"https://ror.org/04tbrah05","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210150380"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aswathy Ammothumkandy","raw_affiliation_strings":["Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210150380"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031661386","display_name":"Luis Corona","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210150380","display_name":"Broad Center","ror":"https://ror.org/04tbrah05","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210150380"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Luis Corona","raw_affiliation_strings":["Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210150380"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058454128","display_name":"Krist\u012bne R\u0101vi\u0146a","orcid":"https://orcid.org/0000-0002-0927-5719","observed_orcids":["https://orcid.org/0000-0002-0927-5719"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kristine Ravina","raw_affiliation_strings":["Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015274828","display_name":"Victoria Wolseley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Victoria Wolseley","raw_affiliation_strings":["Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Physiology & Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Physiology & Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jeremy Nelson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210150380","display_name":"Broad Center","ror":"https://ror.org/04tbrah05","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210150380"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeremy Nelson","raw_affiliation_strings":["Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210150380"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111800397","display_name":"Nadiya Atai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nadiya Atai","raw_affiliation_strings":["Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088337370","display_name":"Aidin Abedi","orcid":"https://orcid.org/0000-0001-8243-3878","observed_orcids":["https://orcid.org/0000-0001-8243-3878"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aidin Abedi","raw_affiliation_strings":["Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Nora Jimenez","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nora Jimenez","raw_affiliation_strings":["Los Angeles General Medical Center, Los Angeles, CA 90033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Los Angeles General Medical Center, Los Angeles, CA 90033, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083359065","display_name":"Michelle Armacost","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I2802549562","display_name":"Rancho Los Amigos National Rehabilitation Center","ror":"https://ror.org/03t3q6164","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328359107","https://openalex.org/I2802549562"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michelle Armacost","raw_affiliation_strings":["Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurology, Rancho Los Amigos National Rehabilitation Center, Downey, CA 90242, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurology, Rancho Los Amigos National Rehabilitation Center, Downey, CA 90242, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I2802549562"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061437798","display_name":"Lina M. D\u2019Orazio","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lina M. D'Orazio","raw_affiliation_strings":["Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063756100","display_name":"Virginia Zuverza-Chavarria","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802549562","display_name":"Rancho Los Amigos National Rehabilitation Center","ror":"https://ror.org/03t3q6164","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328359107","https://openalex.org/I2802549562"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Virginia Zuverza-Chavarria","raw_affiliation_strings":["Department of Psychology, Rancho Los Amigos National Rehabilitation Center, Downey, CA 90242, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, Rancho Los Amigos National Rehabilitation Center, Downey, CA 90242, USA","institution_ids":["https://openalex.org/I2802549562"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024755577","display_name":"Alisha Cayce","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210150380","display_name":"Broad Center","ror":"https://ror.org/04tbrah05","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210150380"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alisha Cayce","raw_affiliation_strings":["Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210150380"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060949196","display_name":"Carol A. McCleary","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carol McCleary","raw_affiliation_strings":["Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015025179","display_name":"George C. Nune","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"George Nune","raw_affiliation_strings":["Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110208194","display_name":"Laura A. Kalayjian","orcid":"https://orcid.org/0009-0000-9988-0797","observed_orcids":["https://orcid.org/0009-0000-9988-0797","https://orcid.org/0000-0003-0489-1560"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laura Kalayjian","raw_affiliation_strings":["Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112874524","display_name":"Darrin J. Lee","orcid":"https://orcid.org/0000-0002-0798-8731","observed_orcids":["https://orcid.org/0000-0002-0798-8731"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Darrin J. Lee","raw_affiliation_strings":["Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Brian Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian Lee","raw_affiliation_strings":["Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064711406","display_name":"Robert Hsiu-Ping Chow","orcid":"https://orcid.org/0000-0002-1322-2070","observed_orcids":["https://orcid.org/0000-0002-1322-2070"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert H. Chow","raw_affiliation_strings":["Department of Physiology & Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089, USA; Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology & Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089, USA; Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059888350","display_name":"Christianne N. Heck","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christianne Heck","raw_affiliation_strings":["Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051719835","display_name":"Jonathan Joseph Russin","orcid":"https://orcid.org/0000-0002-5304-4977","observed_orcids":["https://orcid.org/0000-0002-5304-4977"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan J. Russin","raw_affiliation_strings":["Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016156250","display_name":"Charles Yu Liu","orcid":"https://orcid.org/0000-0001-6423-8577","observed_orcids":["https://orcid.org/0000-0001-6423-8577","https://orcid.org/0000-0002-2404-9138"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Charles Y. Liu","raw_affiliation_strings":["Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089, USA. Electronic address: cliu@usc.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089, USA. Electronic address: cliu@usc.edu","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018440410","display_name":"Jason A.D. Smith","orcid":"https://orcid.org/0000-0002-3209-5804","observed_orcids":["https://orcid.org/0000-0002-3209-5804"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jason A.D. Smith","raw_affiliation_strings":["Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurology, Medical University of South Carolina, Charleston, SC 29425, USA. Electronic address: smijaso1@musc.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurology, Medical University of South Carolina, Charleston, SC 29425, USA. Electronic address: smijaso1@musc.edu","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I153297377"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026519162","display_name":"Michael A. Bonaguidi","orcid":"https://orcid.org/0000-0002-9295-4762","observed_orcids":["https://orcid.org/0000-0002-9295-4762"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210157890","display_name":"Neurological Surgery","ror":"https://ror.org/04r0gp612","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210157890"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael A. Bonaguidi","raw_affiliation_strings":["Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089, USA; Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Biochemistry and Molecular Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Gerontology, University of Southern California, Los Angeles, CA 90089, USA. Electronic address: mbonagui@usc.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089, USA; Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Biochemistry and Molecular Medicine, University of Southern California, Los Angeles, CA 90033, USA; Department of Gerontology, University of Southern California, Los Angeles, CA 90089, USA. Electronic address: mbonagui@usc.edu","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210157890"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5016156250","https://openalex.org/A5018440410","https://openalex.org/A5026519162"],"corresponding_institution_ids":["https://openalex.org/I1174212","https://openalex.org/I153297377","https://openalex.org/I4210157890"],"apc_list":{"value":9350,"currency":"USD","value_usd":9350},"apc_paid":{"value":9350,"currency":"USD","value_usd":9350},"fwci":3.2483,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.93538462,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"32","issue":"2","first_page":"293","last_page":"301.e3"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.00989999994635582,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mesial-temporal-lobe-epilepsy","display_name":"mesial temporal lobe epilepsy","score":0.9890000224113464},{"id":"https://openalex.org/keywords/adult-hippocampal-neurogenesis","display_name":"adult hippocampal neurogenesis","score":0.9100000262260437},{"id":"https://openalex.org/keywords/cognitive-decline","display_name":"cognitive decline","score":0.9789999723434448},{"id":"https://openalex.org/keywords/epilepsy-progression","display_name":"epilepsy progression","score":0.7360000014305115},{"id":"https://openalex.org/keywords/disease-duration","display_name":"disease duration","score":0.8299999833106995},{"id":"https://openalex.org/keywords/verbal-learning","display_name":"verbal learning","score":0.6610000133514404},{"id":"https://openalex.org/keywords/memory-decline","display_name":"memory decline","score":0.7459999918937683},{"id":"https://openalex.org/keywords/auditory-verbal-learning","display_name":"auditory verbal learning","score":0.7570000290870667},{"id":"https://openalex.org/keywords/immature-neurons","display_name":"immature neurons","score":0.8009999990463257},{"id":"https://openalex.org/keywords/granule-neurons","display_name":"granule neurons","score":0.9160000085830688},{"id":"https://openalex.org/keywords/regenerative-medicine","display_name":"regenerative medicine","score":0.7620000243186951}],"concepts":[{"id":"https://openalex.org/C4746552","wikidata":"https://www.wikidata.org/wiki/Q1456827","display_name":"Neurogenesis","level":2,"score":0.9288551211357117},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8674070835113525},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.6345001459121704},{"id":"https://openalex.org/C2984863031","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Cognitive decline","level":4,"score":0.633378803730011},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.5644012093544006},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.41150805354118347},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.23136767745018005},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.13303163647651672},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.1267261803150177},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D004833","descriptor_name":"Epilepsy, Temporal Lobe","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D004833","descriptor_name":"Epilepsy, Temporal Lobe","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055495","descriptor_name":"Neurogenesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1016/j.stem.2024.11.002","doi":"https://doi.org/10.1016/j.stem.2024.11.002","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.stem.2024.11.002","pdf_url":null,"source":{"id":"https://openalex.org/S128124174","display_name":"Cell stem cell","issn_l":"1875-9777","issn":["1875-9777","1934-5909"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Stem Cell","raw_type":"journal-article"},{"id":"doi:10.2139/ssrn.4516136","doi":"https://doi.org/10.2139/ssrn.4516136","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.4516136","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},{"id":"doi:10.1101/2022.09.12.507339","doi":"https://doi.org/10.1101/2022.09.12.507339","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2022.09.12.507339","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2022/09/15/2022.09.12.507339.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmid:39642885","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39642885","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell stem cell","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:11680018","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12807443","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:12807443","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12807443/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Cell Stem Cell","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.stem.2024.11.002","doi":"https://doi.org/10.1016/j.stem.2024.11.002","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.stem.2024.11.002","pdf_url":null,"source":{"id":"https://openalex.org/S128124174","display_name":"Cell stem cell","issn_l":"1875-9777","issn":["1875-9777","1934-5909"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Stem Cell","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G3952172361","display_name":"Evaluation of Cellular Heterogeneity Using Patchclamp and RNA-Seq of Single Cells","funder_award_id":"U01MH098937","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G7979991119","display_name":"Mechanisms Underlying Adult Neural Stem Cell Homeostasis","funder_award_id":"R56AG064077","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G9000863676","display_name":"Neural stem cell rejuvenation through single cell pharmacogenomics","funder_award_id":"R01AG076956","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320308668","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60"},{"id":"https://openalex.org/F4320309839","display_name":"Donald E. and Delia B. Baxter Foundation","ror":"https://ror.org/03ht4bd53"},{"id":"https://openalex.org/F4320309885","display_name":"California Institute of Regenerative Medicine","ror":"https://ror.org/033m8b439"},{"id":"https://openalex.org/F4320312993","display_name":"Rudi Schulte Research Institute","ror":"https://ror.org/01w31ns31"},{"id":"https://openalex.org/F4320322057","display_name":"National Rehabilitation Center","ror":"https://ror.org/04yt6jn66"},{"id":"https://openalex.org/F4320329962","display_name":"Epilepsy Society","ror":null},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4405069442.pdf","grobid_xml":"https://content.openalex.org/works/W4405069442.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W1606616855","https://openalex.org/W1966366706","https://openalex.org/W1999022180","https://openalex.org/W2000520243","https://openalex.org/W2001900093","https://openalex.org/W2008991090","https://openalex.org/W2022686017","https://openalex.org/W2024865093","https://openalex.org/W2029793582","https://openalex.org/W2045194212","https://openalex.org/W2063466545","https://openalex.org/W2067628798","https://openalex.org/W2067856703","https://openalex.org/W2091997230","https://openalex.org/W2096091236","https://openalex.org/W2124571640","https://openalex.org/W2129430574","https://openalex.org/W2136863044","https://openalex.org/W2145664048","https://openalex.org/W2145944042","https://openalex.org/W2152390416","https://openalex.org/W2159872566","https://openalex.org/W2169811841","https://openalex.org/W2192476518","https://openalex.org/W2507621910","https://openalex.org/W2522618573","https://openalex.org/W2747702764","https://openalex.org/W2773029757","https://openalex.org/W2796418566","https://openalex.org/W2891373107","https://openalex.org/W2925056974","https://openalex.org/W2944553435","https://openalex.org/W2945693197","https://openalex.org/W2971946646","https://openalex.org/W2990241163","https://openalex.org/W2999841617","https://openalex.org/W3000488332","https://openalex.org/W3004934488","https://openalex.org/W3041860193","https://openalex.org/W3084222719","https://openalex.org/W3205950297","https://openalex.org/W4223614651","https://openalex.org/W4246364355","https://openalex.org/W4283364953","https://openalex.org/W4283829975","https://openalex.org/W4353087393","https://openalex.org/W6743323337"],"related_works":["https://openalex.org/W4296130134","https://openalex.org/W4407194383","https://openalex.org/W4223614651","https://openalex.org/W2118325881","https://openalex.org/W4224983112","https://openalex.org/W2126293413","https://openalex.org/W122355402","https://openalex.org/W2013071610","https://openalex.org/W4414542989","https://openalex.org/W2086099346"],"abstract_inverted_index":{"Mesial":[0],"temporal":[1],"lobe":[2],"epilepsy":[3,29,61],"(MTLE)":[4],"is":[5,18],"a":[6,81],"syndromic":[7],"disorder":[8],"presenting":[9],"with":[10,47,101,130,143],"seizures":[11],"and":[12,28,63,77,108,133,145],"cognitive":[13,26,56,147],"comorbidities.":[14],"Although":[15],"seizure":[16],"etiology":[17],"increasingly":[19],"understood,":[20],"the":[21,93],"pathophysiological":[22],"mechanisms":[23],"contributing":[24],"to":[25,69,91,116,137],"decline":[27,79],"progression":[30,62],"remain":[31],"less":[32],"recognized.":[33],"We":[34,71],"have":[35],"previously":[36],"shown":[37],"that":[38,73],"adult":[39,127],"hippocampal":[40],"neurogenesis":[41,66,128],"dramatically":[42],"declines":[43],"in":[44],"MTLE":[45,144],"patients":[46,142],"increased":[48],"disease":[49,87],"duration.":[50,88],"Here,":[51],"we":[52],"investigate":[53],"when":[54],"multiple":[55],"domains":[57],"become":[58],"affected":[59],"during":[60],"how":[64,126],"human":[65,96,131],"levels":[67],"contribute":[68],"it.":[70],"find":[72],"intelligence,":[74],"verbal":[75],"learning,":[76],"memory":[78],"at":[80],"critical":[82],"period":[83],"of":[84,95,125],"20":[85],"years":[86],"In":[89],"contrast":[90],"rodents,":[92],"number":[94],"immature":[97],"neurons":[98],"positively":[99],"associates":[100],"auditory":[102],"verbal,":[103],"rather":[104],"than":[105],"visuospatial,":[106],"learning":[107],"memory.":[109],"Moreover,":[110],"this":[111],"association":[112],"does":[113],"not":[114],"apply":[115],"mature":[117],"granule":[118],"neurons.":[119],"Our":[120],"study":[121],"provides":[122],"cellular":[123],"evidence":[124],"corresponds":[129],"cognition":[132],"signifies":[134],"an":[135],"opportunity":[136],"advance":[138],"regenerative":[139],"medicine":[140],"for":[141],"other":[146],"disorders.":[148]},"counts_by_year":[{"year":2026,"cited_by_count":11},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2024-12-06T00:00:00"}