{"id":"https://openalex.org/W4405038544","doi":"https://doi.org/10.1182/blood-2024-198917","title":"Patient-Reported Quality of Life Outcomes with Venetoclax-Based First-Line Combinations in CLL: An Analysis from the Phase 3 GAIA/CLL13 Trial","display_name":"Patient-Reported Quality of Life Outcomes with Venetoclax-Based First-Line Combinations in CLL: An Analysis from the Phase 3 GAIA/CLL13 Trial","publication_year":2024,"publication_date":"2024-11-05","ids":{"openalex":"https://openalex.org/W4405038544","doi":"https://doi.org/10.1182/blood-2024-198917"},"language":"en","primary_location":{"id":"doi:10.1182/blood-2024-198917","doi":"https://doi.org/10.1182/blood-2024-198917","is_oa":true,"landing_page_url":"https://doi.org/10.1182/blood-2024-198917","pdf_url":"https://ashpublications.org/blood/article-pdf/144/Supplement 1/3238/2338795/blood-5990-main.pdf","source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://ashpublications.org/blood/article-pdf/144/Supplement 1/3238/2338795/blood-5990-main.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060879702","display_name":"Moritz F\u00fcrstenau","orcid":"https://orcid.org/0000-0002-6593-0140","observed_orcids":["https://orcid.org/0000-0002-6593-0140"]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Moritz F\u00fcrstenau","raw_affiliation_strings":["1Department I of Internal Medicine, Faculty of Medicine and Cologne University Hospital, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department I of Internal Medicine, Faculty of Medicine and Cologne University Hospital, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031331400","display_name":"Emelie Curovic Rotbain","orcid":"https://orcid.org/0000-0002-4199-772X","observed_orcids":["https://orcid.org/0000-0002-4199-772X"]},"institutions":[{"id":"https://openalex.org/I2802567020","display_name":"Copenhagen University Hospital","ror":"https://ror.org/05bpbnx46","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Emelie Curovic Rotbain","raw_affiliation_strings":["2Department of Hematology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Department of Hematology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark","institution_ids":["https://openalex.org/I2802567020","https://openalex.org/I2802709434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043677389","display_name":"Laura Eurelings","orcid":"https://orcid.org/0000-0002-1830-2213","observed_orcids":["https://orcid.org/0000-0002-1830-2213"]},"institutions":[{"id":"https://openalex.org/I4210091119","display_name":"Albert Schweitzer Ziekenhuis","ror":"https://ror.org/00e8ykd54","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210091119"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Laura Eurelings","raw_affiliation_strings":["3Albert Schweitzer Ziekenhuis, Dordrecht, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Albert Schweitzer Ziekenhuis, Dordrecht, Netherlands","institution_ids":["https://openalex.org/I4210091119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067592137","display_name":"Sandra Robrecht","orcid":"https://orcid.org/0000-0001-8848-6655","observed_orcids":["https://orcid.org/0000-0001-8848-6655"]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4405268083","display_name":"Deutsche CLL Studiengruppe (DCLLSG)","ror":"https://ror.org/05qrww479","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I4405268083"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sandra Robrecht","raw_affiliation_strings":["4German CLL Study Group, University of Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4German CLL Study Group, University of Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4405268083"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020760036","display_name":"Julia von Tresckow","orcid":"https://orcid.org/0000-0001-5873-4603","observed_orcids":["https://orcid.org/0000-0001-5873-4603"]},"institutions":[{"id":"https://openalex.org/I4210119759","display_name":"Essen University Hospital","ror":"https://ror.org/02na8dn90","country_code":"DE","type":"funder","lineage":["https://openalex.org/I4210119759"]},{"id":"https://openalex.org/I62318514","display_name":"University of Duisburg-Essen","ror":"https://ror.org/04mz5ra38","country_code":"DE","type":"education","lineage":["https://openalex.org/I62318514"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Julia Von Tresckow","raw_affiliation_strings":["5Clinic for Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"5Clinic for Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany","institution_ids":["https://openalex.org/I4210119759","https://openalex.org/I62318514"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091226561","display_name":"Adam Giza","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]},{"id":"https://openalex.org/I4405268083","display_name":"Deutsche CLL Studiengruppe (DCLLSG)","ror":"https://ror.org/05qrww479","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I4405268083"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Adam Giza","raw_affiliation_strings":["6Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf; German CLL Study Group, University of Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"6Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf; German CLL Study Group, University of Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755","https://openalex.org/I4405268083"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109125166","display_name":"Michael Gregor","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119500","display_name":"Luzerner Kantonsspital","ror":"https://ror.org/02zk3am42","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210119500"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Michael Gregor","raw_affiliation_strings":["7Division of Hematology, Cantonal Hospital of Lucerne, Lucerne, Switzerland, Lucerne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"7Division of Hematology, Cantonal Hospital of Lucerne, Lucerne, Switzerland, Lucerne, Switzerland","institution_ids":["https://openalex.org/I4210119500"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077471584","display_name":"Patrick D. Thornton","orcid":"https://orcid.org/0000-0002-5126-9590","observed_orcids":["https://orcid.org/0000-0002-5126-9590"]},"institutions":[{"id":"https://openalex.org/I142762351","display_name":"Royal College of Surgeons in Ireland","ror":"https://ror.org/01hxy9878","country_code":"IE","type":"education","lineage":["https://openalex.org/I142762351"]},{"id":"https://openalex.org/I2801846703","display_name":"Beaumont Hospital","ror":"https://ror.org/043mzjj67","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I2801846703"]},{"id":"https://openalex.org/I4210103332","display_name":"Cancer Trials Ireland","ror":"https://ror.org/01dpkyq75","country_code":"IE","type":"facility","lineage":["https://openalex.org/I4210103332"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Patrick Thornton","raw_affiliation_strings":["8Department of Haematology, Beaumont Hospital, RCSI, Cancer Trials Ireland, Dublin, Dublin, IRL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"8Department of Haematology, Beaumont Hospital, RCSI, Cancer Trials Ireland, Dublin, Dublin, IRL","institution_ids":["https://openalex.org/I142762351","https://openalex.org/I2801846703","https://openalex.org/I4210103332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027978059","display_name":"Philipp Bernhard Staber","orcid":"https://orcid.org/0000-0001-6729-7708","observed_orcids":["https://orcid.org/0000-0001-6729-7708"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Philipp Bernhard Staber","raw_affiliation_strings":["9Department of Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"9Department of Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025358969","display_name":"Tamar Tadmor","orcid":"https://orcid.org/0000-0002-3435-8612","observed_orcids":["https://orcid.org/0000-0002-3435-8612"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tamar Tadmor","raw_affiliation_strings":["10Bnai Zion, Haifa, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"10Bnai Zion, Haifa, Israel","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020419523","display_name":"Vesa Lindstr\u00f6m","orcid":"https://orcid.org/0000-0001-5724-9120","observed_orcids":["https://orcid.org/0000-0001-5724-9120"]},"institutions":[{"id":"https://openalex.org/I133731052","display_name":"University of Helsinki","ror":"https://ror.org/040af2s02","country_code":"FI","type":"education","lineage":["https://openalex.org/I133731052"]},{"id":"https://openalex.org/I2800394112","display_name":"Helsinki University Hospital","ror":"https://ror.org/02e8hzf44","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2800394112","https://openalex.org/I4210166427"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Vesa Lindstr\u00f6m","raw_affiliation_strings":["11Comprehensive Cancer Center, Department of Hematology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"11Comprehensive Cancer Center, Department of Hematology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland","institution_ids":["https://openalex.org/I133731052","https://openalex.org/I2800394112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030094794","display_name":"Gunnar Juliusson","orcid":"https://orcid.org/0000-0002-7911-7265","observed_orcids":["https://orcid.org/0000-0002-7911-7265"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Gunnar Juliusson","raw_affiliation_strings":["12Department of Hematology, Lund University Cancer Center, Lund, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"12Department of Hematology, Lund University Cancer Center, Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069303553","display_name":"Ann M. Janssens","orcid":"https://orcid.org/0000-0002-1812-412X","observed_orcids":["https://orcid.org/0000-0002-1812-412X"]},"institutions":[{"id":"https://openalex.org/I2800231306","display_name":"Universitair Ziekenhuis Leuven","ror":"https://ror.org/0424bsv16","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2800231306"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Ann Janssens","raw_affiliation_strings":["13University Hospitals Leuven, Leuven, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"13University Hospitals Leuven, Leuven, Belgium","institution_ids":["https://openalex.org/I2800231306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088105442","display_name":"Christof Schneider","orcid":"https://orcid.org/0000-0001-9719-7345","observed_orcids":["https://orcid.org/0000-0001-9719-7345"]},"institutions":[{"id":"https://openalex.org/I4210155144","display_name":"University Hospital Ulm","ror":"https://ror.org/05emabm63","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210155144"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christof Schneider","raw_affiliation_strings":["14Department of Internal Medicine III, Division of CLL, University Hospital Ulm, Ulm, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"14Department of Internal Medicine III, Division of CLL, University Hospital Ulm, Ulm, Germany","institution_ids":["https://openalex.org/I4210155144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033414675","display_name":"Thomas Noesslinger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210101126","display_name":"Hanusch Hospital","ror":"https://ror.org/0163qhr63","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I4210101126"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Thomas Noesslinger","raw_affiliation_strings":["15Hanusch Hospital, Vienna, AUT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"15Hanusch Hospital, Vienna, AUT","institution_ids":["https://openalex.org/I4210101126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078712773","display_name":"Martin Andres","orcid":"https://orcid.org/0000-0001-9891-2988","observed_orcids":["https://orcid.org/0000-0001-9891-2988"]},"institutions":[{"id":"https://openalex.org/I118564535","display_name":"University of Bern","ror":"https://ror.org/02k7v4d05","country_code":"CH","type":"education","lineage":["https://openalex.org/I118564535"]},{"id":"https://openalex.org/I2801112126","display_name":"University Hospital of Bern","ror":"https://ror.org/01q9sj412","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2801112126"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Martin Andres","raw_affiliation_strings":["16Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"16Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland","institution_ids":["https://openalex.org/I118564535","https://openalex.org/I2801112126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083673759","display_name":"Adrian Schmidt","orcid":"https://orcid.org/0000-0002-6315-2592","observed_orcids":["https://orcid.org/0000-0002-6315-2592"]},"institutions":[{"id":"https://openalex.org/I2799963127","display_name":"Triemli Hospital","ror":"https://ror.org/03kpdys72","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2799963127","https://openalex.org/I4405256532"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Adrian Schmidt","raw_affiliation_strings":["17Stadtspital Z\u00fcrich Triemli, Z\u00fcrich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"17Stadtspital Z\u00fcrich Triemli, Z\u00fcrich, Switzerland","institution_ids":["https://openalex.org/I2799963127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079949206","display_name":"Elisabeth Vandenberghe","orcid":"https://orcid.org/0000-0002-7731-9437","observed_orcids":["https://orcid.org/0000-0002-7731-9437"]},"institutions":[{"id":"https://openalex.org/I4210154619","display_name":"St. James's Hospital","ror":"https://ror.org/04c6bry31","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I4210154619"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Elisabeth Vandenberghe","raw_affiliation_strings":["18St. James's Hospital, Dublin, IRL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"18St. James's Hospital, Dublin, IRL","institution_ids":["https://openalex.org/I4210154619"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090335644","display_name":"Lev Shvidel","orcid":"https://orcid.org/0000-0002-0398-9390","observed_orcids":["https://orcid.org/0000-0002-0398-9390"]},"institutions":[{"id":"https://openalex.org/I2800052317","display_name":"Kaplan Medical Center","ror":"https://ror.org/00t0n9020","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2800052317","https://openalex.org/I64767286"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Lev Shvidel","raw_affiliation_strings":["19Kaplan Medical Center, Rehovot, ISR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"19Kaplan Medical Center, Rehovot, ISR","institution_ids":["https://openalex.org/I2800052317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055309337","display_name":"Christian Bj\u00f8rn Poulsen","orcid":"https://orcid.org/0000-0001-9785-1378","observed_orcids":["https://orcid.org/0000-0001-9785-1378"]},"institutions":[{"id":"https://openalex.org/I4210087803","display_name":"Zealand University Hospital","ror":"https://ror.org/00363z010","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2799668677","https://openalex.org/I2802567020","https://openalex.org/I4210087803"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Christian Bj\u00f8rn Poulsen","raw_affiliation_strings":["20Department of Hematology, Zealand University Hospital, Roskilde, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"20Department of Hematology, Zealand University Hospital, Roskilde, Denmark","institution_ids":["https://openalex.org/I4210087803"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024356923","display_name":"Henrik Frederiksen","orcid":"https://orcid.org/0000-0001-8905-0220","observed_orcids":["https://orcid.org/0000-0001-8905-0220"]},"institutions":[{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"funder","lineage":["https://openalex.org/I2801498763"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Henrik Frederiksen","raw_affiliation_strings":["21Department of Hematology, Odense University Hospital, Odense, DNK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"21Department of Hematology, Odense University Hospital, Odense, DNK","institution_ids":["https://openalex.org/I2801498763"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011876375","display_name":"Caspar da Cunha\u2010Bang","orcid":"https://orcid.org/0000-0002-7800-3098","observed_orcids":["https://orcid.org/0000-0002-7800-3098"]},"institutions":[{"id":"https://openalex.org/I2802567020","display_name":"Copenhagen University Hospital","ror":"https://ror.org/05bpbnx46","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Caspar Da Cunha-Bang","raw_affiliation_strings":["2Department of Hematology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Department of Hematology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark","institution_ids":["https://openalex.org/I2802567020","https://openalex.org/I2802709434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020368113","display_name":"Kourosh Lotfi","orcid":"https://orcid.org/0000-0001-5797-7232","observed_orcids":["https://orcid.org/0000-0001-5797-7232"]},"institutions":[{"id":"https://openalex.org/I102134673","display_name":"Link\u00f6ping University","ror":"https://ror.org/05ynxx418","country_code":"SE","type":"education","lineage":["https://openalex.org/I102134673"]},{"id":"https://openalex.org/I4210151885","display_name":"Link\u00f6ping University Hospital","ror":"https://ror.org/05h1aye87","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210151885"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Kourosh Lotfi","raw_affiliation_strings":["22University Hospital/Linkoping University, Linkoping, SWE"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"22University Hospital/Linkoping University, Linkoping, SWE","institution_ids":["https://openalex.org/I102134673","https://openalex.org/I4210151885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024949273","display_name":"Rogier Mous","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Rogier Mous","raw_affiliation_strings":["23Department of Hematology, University Medical Center Utrecht, Amsterdam, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"23Department of Hematology, University Medical Center Utrecht, Amsterdam, Netherlands","institution_ids":["https://openalex.org/I3018483916"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010979808","display_name":"Martine E.D. Chamuleau","orcid":"https://orcid.org/0000-0002-0123-9182","observed_orcids":["https://orcid.org/0000-0002-0123-9182"]},"institutions":[{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Martine E.D. Chamuleau","raw_affiliation_strings":["24Department of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"24Department of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, Netherlands","institution_ids":["https://openalex.org/I911458345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041636485","display_name":"Ka Lung Wu","orcid":"https://orcid.org/0000-0001-6042-978X","observed_orcids":["https://orcid.org/0000-0001-6042-978X"]},"institutions":[{"id":"https://openalex.org/I4210150429","display_name":"Ziekenhuisnetwerk Antwerpen Stuivenberg","ror":"https://ror.org/05dpzfc16","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I4210150429","https://openalex.org/I4405261247"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Ka Lung Wu","raw_affiliation_strings":["25ZNA Stuivenberg, Antwerp, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"25ZNA Stuivenberg, Antwerp, Belgium","institution_ids":["https://openalex.org/I4210150429"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081794957","display_name":"Margriet Oosterveld","orcid":"https://orcid.org/0000-0002-6742-9261","observed_orcids":["https://orcid.org/0000-0002-6742-9261"]},"institutions":[{"id":"https://openalex.org/I4210113935","display_name":"Canisius-Wilhelmina Ziekenhuis","ror":"https://ror.org/027vts844","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210113935"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Margriet Oosterveld","raw_affiliation_strings":["26Canisius-Wilhelmina Hospital, Nijmegen, NLD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"26Canisius-Wilhelmina Hospital, Nijmegen, NLD","institution_ids":["https://openalex.org/I4210113935"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003178415","display_name":"Jes\u00fas Duque\u2010Afonso","orcid":"https://orcid.org/0000-0002-8287-5673","observed_orcids":["https://orcid.org/0000-0002-8287-5673"]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jesus Duque-Afonso","raw_affiliation_strings":["27Univ. of Freiburg, Freiburg, DEU"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"27Univ. of Freiburg, Freiburg, DEU","institution_ids":["https://openalex.org/I161046081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113696918","display_name":"Christian Bogner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christian Bogner","raw_affiliation_strings":["28Klinikum Landshut, Landshut, DEU"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"28Klinikum Landshut, Landshut, DEU","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058629026","display_name":"Thomas E. Wolff","orcid":"https://orcid.org/0000-0001-9877-1097","observed_orcids":["https://orcid.org/0000-0001-9877-1097"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thomas Wolff","raw_affiliation_strings":["29Onkologie-Lerchenfeld, Hamburg, DEU"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"29Onkologie-Lerchenfeld, Hamburg, DEU","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004741011","display_name":"Johannes Schetelig","orcid":"https://orcid.org/0000-0002-2780-2981","observed_orcids":["https://orcid.org/0000-0002-2780-2981"]},"institutions":[{"id":"https://openalex.org/I4210162051","display_name":"University Hospital Carl Gustav Carus","ror":"https://ror.org/04za5zm41","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210162051"]},{"id":"https://openalex.org/I78650965","display_name":"Technische Universit\u00e4t Dresden","ror":"https://ror.org/042aqky30","country_code":"DE","type":"education","lineage":["https://openalex.org/I78650965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Johannes Schetelig","raw_affiliation_strings":["30Department of Internal Medicine I, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"30Department of Internal Medicine I, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I4210162051","https://openalex.org/I78650965"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052605376","display_name":"Ursula Vehling\u2010Kaiser","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ursula Vehling-Kaiser","raw_affiliation_strings":["31Outpatient Clinic, Landshut, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"31Outpatient Clinic, Landshut, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016777547","display_name":"Christoph van Roye","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christoph van Roye","raw_affiliation_strings":["32Onkologie Koblenz, Koblenz, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"32Onkologie Koblenz, Koblenz, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044687687","display_name":"Nadine Kutsch","orcid":"https://orcid.org/0000-0001-9559-8575","observed_orcids":["https://orcid.org/0000-0001-9559-8575"]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]},{"id":"https://openalex.org/I4405268083","display_name":"Deutsche CLL Studiengruppe (DCLLSG)","ror":"https://ror.org/05qrww479","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I4405268083"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Nadine Kutsch","raw_affiliation_strings":["6Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf; German CLL Study Group, University of Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"6Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf; German CLL Study Group, University of Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755","https://openalex.org/I4405268083"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070519285","display_name":"Anna Maria Fink","orcid":"https://orcid.org/0009-0002-9903-283X","observed_orcids":["https://orcid.org/0009-0002-9903-283X"]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Anna Maria Fink","raw_affiliation_strings":["1Department I of Internal Medicine, Faculty of Medicine and Cologne University Hospital, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department I of Internal Medicine, Faculty of Medicine and Cologne University Hospital, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061682665","display_name":"Kirsten Fischer","orcid":"https://orcid.org/0009-0006-6169-9152","observed_orcids":["https://orcid.org/0009-0006-6169-9152"]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Kirsten Fischer","raw_affiliation_strings":["1Department I of Internal Medicine, Faculty of Medicine and Cologne University Hospital, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Department I of Internal Medicine, Faculty of Medicine and Cologne University Hospital, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Emily Holmes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4405268083","display_name":"Deutsche CLL Studiengruppe (DCLLSG)","ror":"https://ror.org/05qrww479","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I4405268083"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Emily Holmes","raw_affiliation_strings":["33German CLL Study Group, University of Cologne, Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"33German CLL Study Group, University of Cologne, Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4405268083"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071552171","display_name":"Matthias Ritgen","orcid":"https://orcid.org/0000-0002-0957-3804","observed_orcids":["https://orcid.org/0000-0002-0957-3804"]},"institutions":[{"id":"https://openalex.org/I4210112713","display_name":"University Hospital Schleswig-Holstein","ror":"https://ror.org/01tvm6f46","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210112713"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Matthias Ritgen","raw_affiliation_strings":["34Department of Internal Medicine II (Hematology/Oncology), University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"34Department of Internal Medicine II (Hematology/Oncology), University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany","institution_ids":["https://openalex.org/I4210112713"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025985392","display_name":"Eugen Tausch","orcid":"https://orcid.org/0000-0002-9503-1226","observed_orcids":["https://orcid.org/0000-0002-9503-1226"]},"institutions":[{"id":"https://openalex.org/I4210155144","display_name":"University Hospital Ulm","ror":"https://ror.org/05emabm63","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210155144"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Eugen Tausch","raw_affiliation_strings":["14Department of Internal Medicine III, Division of CLL, University Hospital Ulm, Ulm, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"14Department of Internal Medicine III, Division of CLL, University Hospital Ulm, Ulm, Germany","institution_ids":["https://openalex.org/I4210155144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019866348","display_name":"Stephan Stilgenbauer","orcid":"https://orcid.org/0000-0002-6830-9296","observed_orcids":["https://orcid.org/0000-0002-6830-9296"]},"institutions":[{"id":"https://openalex.org/I4210155144","display_name":"University Hospital Ulm","ror":"https://ror.org/05emabm63","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210155144"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stephan Stilgenbauer","raw_affiliation_strings":["14Department of Internal Medicine III, Division of CLL, University Hospital Ulm, Ulm, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"14Department of Internal Medicine III, Division of CLL, University Hospital Ulm, Ulm, Germany","institution_ids":["https://openalex.org/I4210155144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076077834","display_name":"Michael J. Hallek","orcid":"https://orcid.org/0000-0002-7425-4455","observed_orcids":["https://orcid.org/0000-0002-7425-4455"]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Michael J. Hallek","raw_affiliation_strings":["35University of Cologne, Cologne, DEU"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"35University of Cologne, Cologne, DEU","institution_ids":["https://openalex.org/I180923762"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064164625","display_name":"Arnon Philip Kater","orcid":"https://orcid.org/0000-0003-3190-1891","observed_orcids":["https://orcid.org/0000-0003-3190-1891"]},"institutions":[{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Arnon P. Kater","raw_affiliation_strings":["36Amsterdam University Medical Center, Amsterdam, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"36Amsterdam University Medical Center, Amsterdam, Netherlands","institution_ids":["https://openalex.org/I4210151833"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057884204","display_name":"Carsten Utoft Niemann","orcid":"https://orcid.org/0000-0001-9880-5242","observed_orcids":["https://orcid.org/0000-0001-9880-5242"]},"institutions":[{"id":"https://openalex.org/I2802567020","display_name":"Copenhagen University Hospital","ror":"https://ror.org/05bpbnx46","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Carsten Utoft Niemann","raw_affiliation_strings":["2Department of Hematology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Department of Hematology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark","institution_ids":["https://openalex.org/I2802567020","https://openalex.org/I2802709434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004217461","display_name":"Mark\u2010David Levin","orcid":"https://orcid.org/0000-0003-2139-3547","observed_orcids":["https://orcid.org/0000-0003-2139-3547"]},"institutions":[{"id":"https://openalex.org/I4210091119","display_name":"Albert Schweitzer Ziekenhuis","ror":"https://ror.org/00e8ykd54","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210091119"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Mark-David Levin","raw_affiliation_strings":["37Albert Schweitzer Hospital, Dordrecht, Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"37Albert Schweitzer Hospital, Dordrecht, Netherlands","institution_ids":["https://openalex.org/I4210091119"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088826331","display_name":"Barbara F. Eichhorst","orcid":"https://orcid.org/0000-0001-9990-6918","observed_orcids":["https://orcid.org/0000-0001-9990-6918"]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Barbara F. Eichhorst","raw_affiliation_strings":["38University Hospital Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"38University Hospital Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762","https://openalex.org/I4210153755"]}]}],"institutions":[],"countries_distinct_count":10,"institutions_distinct_count":37,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5000,"currency":"USD","value_usd":5000},"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"144","issue":"Supplement 1","first_page":"3238","last_page":"3238"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11157","display_name":"Chronic Lymphocytic Leukemia Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11157","display_name":"Chronic Lymphocytic Leukemia Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10178","display_name":"Cancer survivorship and care","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-lymphocytic-leukemia","display_name":"chronic lymphocytic leukemia","score":0.9950000047683716},{"id":"https://openalex.org/keywords/venetoclax","display_name":"venetoclax","score":0.9559999704360962},{"id":"https://openalex.org/keywords/first-line-treatment","display_name":"first-line therapy","score":0.6629999876022339},{"id":"https://openalex.org/keywords/health-related-quality-of-life","display_name":"health-related quality of life","score":0.8309999704360962},{"id":"https://openalex.org/keywords/patient-reported-outcomes","display_name":"patient-reported outcomes","score":0.8019999861717224},{"id":"https://openalex.org/keywords/chemoimmunotherapy","display_name":"chemoimmunotherapy","score":0.9549999833106995},{"id":"https://openalex.org/keywords/minimal-important-difference","display_name":"minimal important difference","score":0.7429999709129333}],"concepts":[{"id":"https://openalex.org/C2779675984","wikidata":"https://www.wikidata.org/wiki/Q23671272","display_name":"Venetoclax","level":4,"score":0.916000247001648},{"id":"https://openalex.org/C2777607594","wikidata":"https://www.wikidata.org/wiki/Q389496","display_name":"Obinutuzumab","level":4,"score":0.7452995777130127},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6401078701019287},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.6140738129615784},{"id":"https://openalex.org/C2780790343","wikidata":"https://www.wikidata.org/wiki/Q5090610","display_name":"Chemoimmunotherapy","level":4,"score":0.6082863807678223},{"id":"https://openalex.org/C2780653079","wikidata":"https://www.wikidata.org/wiki/Q412323","display_name":"Rituximab","level":3,"score":0.509540855884552},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5052056908607483},{"id":"https://openalex.org/C2777609679","wikidata":"https://www.wikidata.org/wiki/Q5971015","display_name":"IGHV@","level":4,"score":0.45486775040626526},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.37579596042633057},{"id":"https://openalex.org/C2777938653","wikidata":"https://www.wikidata.org/wiki/Q1088156","display_name":"Chronic lymphocytic leukemia","level":3,"score":0.2548080086708069},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.2345816195011139},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.19487157464027405},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1182/blood-2024-198917","doi":"https://doi.org/10.1182/blood-2024-198917","is_oa":true,"landing_page_url":"https://doi.org/10.1182/blood-2024-198917","pdf_url":"https://ashpublications.org/blood/article-pdf/144/Supplement 1/3238/2338795/blood-5990-main.pdf","source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},{"id":"pmh:oai:sdu.dk:openaire_cris_publications/d3e65eb6-34c8-48da-aac2-b311a8db52a7","doi":null,"is_oa":false,"landing_page_url":"https://portal.findresearcher.sdu.dk/da/publications/d3e65eb6-34c8-48da-aac2-b311a8db52a7","pdf_url":null,"source":{"id":"https://openalex.org/S4306400423","display_name":"University of Southern Denmark Research Portal (University of Southern Denmark)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177969490","host_organization_name":"University of Southern Denmark","host_organization_lineage":["https://openalex.org/I177969490"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/conferenceObject"},{"id":"pmh:oai:sdu.dk:openaire_cris_publications/2592ce31-cec1-439e-9209-aa6aad5136a5","doi":null,"is_oa":false,"landing_page_url":"https://portal.findresearcher.sdu.dk/da/publications/2592ce31-cec1-439e-9209-aa6aad5136a5","pdf_url":null,"source":{"id":"https://openalex.org/S4306400423","display_name":"University of Southern Denmark Research Portal (University of Southern Denmark)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177969490","host_organization_name":"University of Southern Denmark","host_organization_lineage":["https://openalex.org/I177969490"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":{"id":"doi:10.1182/blood-2024-198917","doi":"https://doi.org/10.1182/blood-2024-198917","is_oa":true,"landing_page_url":"https://doi.org/10.1182/blood-2024-198917","pdf_url":"https://ashpublications.org/blood/article-pdf/144/Supplement 1/3238/2338795/blood-5990-main.pdf","source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"sustainable_development_goals_aurora":[{"display_name":"Responsible consumption and production","id":"https://metadata.un.org/sdg/12","score":0.41999998688697815}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320307105","display_name":"Amgen","ror":"https://ror.org/03g03ge92"},{"id":"https://openalex.org/F4320307758","display_name":"Eli Lilly and Company","ror":"https://ror.org/01qat3289"},{"id":"https://openalex.org/F4320307770","display_name":"AstraZeneca","ror":"https://ror.org/04r9x1a08"},{"id":"https://openalex.org/F4320308573","display_name":"Gilead Sciences","ror":"https://ror.org/056546b03"},{"id":"https://openalex.org/F4320308970","display_name":"Teva Pharmaceutical Industries","ror":"https://ror.org/01wfv3m53"},{"id":"https://openalex.org/F4320309052","display_name":"Alexion Pharmaceuticals","ror":"https://ror.org/031ywxc85"},{"id":"https://openalex.org/F4320309086","display_name":"Celgene","ror":"https://ror.org/0527yg379"},{"id":"https://openalex.org/F4320310420","display_name":"CSL Behring","ror":"https://ror.org/01jxhxv92"},{"id":"https://openalex.org/F4320315663","display_name":"Sunesis","ror":"https://ror.org/0187pm092"},{"id":"https://openalex.org/F4320317235","display_name":"BeiGene","ror":"https://ror.org/012v2c923"},{"id":"https://openalex.org/F4320317544","display_name":"Incyte","ror":"https://ror.org/00cvzzg84"},{"id":"https://openalex.org/F4320322436","display_name":"Novo Nordisk","ror":"https://ror.org/0435rc536"},{"id":"https://openalex.org/F4320323024","display_name":"Astellas Pharma","ror":"https://ror.org/01cjash87"},{"id":"https://openalex.org/F4320327470","display_name":"Swedish Orphan Biovitrum","ror":"https://ror.org/04asvbz37"},{"id":"https://openalex.org/F4320328455","display_name":"Ipsen","ror":"https://ror.org/00d801g55"},{"id":"https://openalex.org/F4320328692","display_name":"Medac","ror":"https://ror.org/05e0gzh77"},{"id":"https://openalex.org/F4320332193","display_name":"Genentech","ror":"https://ror.org/04gndp242"},{"id":"https://openalex.org/F4320338413","display_name":"Cilag","ror":"https://ror.org/02fe4h741"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4405038544.pdf","grobid_xml":"https://content.openalex.org/works/W4405038544.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2602605464","https://openalex.org/W3093108960","https://openalex.org/W4411340103","https://openalex.org/W2580497094","https://openalex.org/W3102573380","https://openalex.org/W4380150597","https://openalex.org/W4402585357","https://openalex.org/W4407876256","https://openalex.org/W4220918921","https://openalex.org/W4380084722"],"abstract_inverted_index":{"Background":[0],"The":[1,132,367,580],"phase":[2],"3":[3,73],"GAIA/CLL13":[4,62],"trial":[5],"recently":[6],"demonstrated":[7],"superior":[8],"progression-free":[9],"survival":[10],"for":[11,250,255,439,654],"time-limited":[12],"venetoclax-obinutuzumab":[13],"(GV)":[14,263,479],"and":[15,23,82,95,103,109,150,176,189,237,248,264,270,300,388,404,428,434,448,480,497,541,544,604,622,649,670],"venetoclax-obinutuzumab-ibrutinib":[16],"(GIV)":[17],"compared":[18,431,490,593],"to":[19,432,491,498,594,675],"both,":[20],"chemoimmunotherapy":[21],"(CIT)":[22],"venetoclax-rituximab":[24],"(RV)":[25],"in":[26,88,379,425,458,462,484,525,547,573,619,643,660,699],"the":[27,61,100,140,268,306,312,315,322,327,348,356,380,426,504,517,533,556,563,571,574,639,661,667,671],"first-line":[28],"treatment":[29,197,278,332,341,377,466,630,642,684],"of":[30,36,39,43,55,117,119,130,196,202,210,277,331,456,472,506,513,582,587,641,663,695],"CLL.":[31,700],"Currently,":[32],"no":[33,318],"direct":[34],"comparisons":[35],"health-related":[37],"quality":[38],"life":[40],"(QoL)":[41],"measures":[42,621],"different":[44,696],"venetoclax":[45,697],"regimens":[46],"are":[47],"available.":[48],"Here,":[49],"we":[50],"report":[51],"a":[52,114,127,146,154,172,469,511,550,583,679],"preplanned":[53],"analysis":[54],"patient-reported":[56],"QoL":[57,620,664],"outcomes":[58,694],"(PRO)":[59],"from":[60,143,194,281,303,414,530,553,566],"trial.":[63],"Methods":[64],"PRO":[65],"questionnaires":[66],"were":[67,97,192,221,243,257,309,416,436,460,626,634,652],"completed":[68,171],"at":[69,174,177,179,203,215,223,226,229,232,235,239,334,364,536,559,577],"baseline":[70,175],"(BL),":[71],"month":[72],"(MO3),":[74],"MO6,":[75,230],"MO9,":[76,233],"MO12,":[77],"MO15,":[78],"MO18,":[79],"MO21,":[80],"MO24":[81,365],"then":[83],"annually":[84],"until":[85,186,198],"MO60.":[86],"Changes":[87],"functioning":[89,107,445,624],"scales,":[90],"global":[91],"health":[92],"status":[93],"(GHS)/QoL":[94],"symptoms":[96],"assessed":[98],"using":[99,153],"EORTC":[101],"QLQ-C30":[102],"QLQ-CLL16":[104],"questionnaires.":[105],"For":[106,168,610],"scales":[108,123,625],"GHS/QoL,":[110],"higher":[111,124,128,523,545,590,680],"scores":[112,125,524,546],"indicate":[113],"better":[115],"level":[116,129],"functioning/improvement":[118],"QoL,":[120],"on":[121],"symptom":[122,368,681],"show":[126],"symptoms.":[131],"minimal":[133,141],"important":[134],"difference":[135,659],"(MID)":[136],"was":[137,151,324,362,486,589],"defined":[138],"as":[139,157],"change":[142,280,552],"BL":[144,241,253,304,415,531,554,567],"indicating":[145],"clinically":[147,584],"meaningful":[148,453,585],"improvement":[149,190,201,359],"calculated":[152,193],"distribution-based":[155],"approach":[156],"previously":[158],"described":[159],"(e.g.":[160],"van":[161],"der":[162],"Straten":[163],"et":[164],"al.,":[165],"Blood":[166],"2023).":[167],"patients":[169,212,246,338,464,520,611,644,655],"who":[170],"questionnaire":[173],"least":[178,204,216],"one":[180,217],"further":[181],"time":[182,185],"point":[183],"post-baseline,":[184],"deterioration":[187,199,586],"(TUD)":[188],"(TUI)":[191],"start":[195],"or":[200,615],"MID.":[205],"Results":[206],"In":[207,267,314,347,516],"total,":[208],"863":[209],"926":[211],"(93.2%)":[213],"returned":[214],"questionnaire.":[218],"Completion":[219],"rates":[220],"76.0%":[222],"BL,":[224,282],"72.7%":[225],"MO3,":[227],"69.4%":[228],"61.2%":[231],"75.4%":[234],"MO12":[236],"49.2%":[238],"MO15.":[240],"characteristics":[242],"balanced":[244],"between":[245,666],"evaluable":[247],"non-evaluable":[249],"QoL.":[251],"Mean":[252],"values":[254],"GHS":[256,273],"68.4":[258],"(CIT),":[259,475],"67.9":[260],"(RV),":[261,477],"67.8":[262],"69.5":[265],"(GIV).":[266,482],"RV":[269,381,433,499,600],"GV":[271,389,435,509,605,614],"arm,":[272,317,519],"improved":[274,374],"after":[275,376,629,638],"initiation":[276,378],"(mean":[279],"RV:":[283],"+5.2":[284],"[MO3];":[285],"+6.1":[286],"[MO6];":[287],"+8.8":[288],"[MO9];":[289],"+9.4":[290],"[MO12];":[291],"+8.4":[292],"[MO15];":[293],"GV:":[294],"+5.5;":[295],"+5.1;":[296],"+9.0;":[297],"+9.3;":[298],"+10.1)":[299],"mean":[301,319,358,412,528,551,564],"changes":[302,413,529,565],"above":[305,321,360,532,555],"MID":[307,323,361,372,534,557,572],"(5.9)":[308],"maintained":[310],"throughout":[311],"study.":[313],"GIV":[316,398,429,489,507,518,592],"increase":[320],"observed":[325,627],"during":[326,683],"first":[328,357],"12":[329],"months":[330,474],"but":[333],"MO15":[335],"when":[336,691],"most":[337,463],"had":[339],"finished":[340],"(+2.4;":[342],"+0.2;":[343],"+2.5;":[344],"+4.4;":[345],"+10.2).":[346],"CIT":[349,405,427,492,595],"arm":[350,382,390],"(+1.3;":[351],"-0.6;":[352],"+4.9;":[353],"+5.0;":[354],"+5.4),":[355],"reported":[363,438,461,522,636],"(+6.1).":[366],"burden":[369,682],"(QLQ-CLL16":[370],"questionnaire,":[371],"7.3)":[373],"promptly":[375],"(-5.4;":[383],"-5.3;":[384],"-5.5;":[385,394],"-5.8;":[386],"-7.3)":[387],"(-5.0;":[391],"-4.3;":[392],"-5.6;":[393],"-7.8),":[395],"while":[396,503,562,647],"with":[397,468,488,527,549,591,613,685],"(-0.2;":[399],"+1.1;":[400],"0.0;":[401],"-1.5;":[402],"-5.1)":[403],"(-1.3;":[406],"-1.7;":[407],"-3.8;":[408],"-4.0;":[409],"-3.7)":[410],"similar":[411],"reached":[417],"later.":[418],"Similar":[419,632],"temporal":[420],"dynamics,":[421],"i.e.":[422],"later":[423,648],"improvements":[424,454,618,633,651,665],"arms":[430,467,576],"also":[437,521],"physical":[440,449],"functioning,":[441,443],"role":[442],"social":[444],"(all":[446],"QLQ-C30)":[447],"condition":[450],"(QLQ-CLL16).":[451],"Clinically":[452],"(\u2265MID":[455],"8.9)":[457],"fatigue":[459],"across":[465],"median":[470],"TUI":[471],"7.5":[473],"5.4":[476],"5.7":[478],"5.8":[481],"TUD":[483],"nausea/vomiting":[485],"worse":[487],"(HR":[493,500,601,606],"1.46":[494],"[95%CI":[495],"1.08-1.98])":[496],"1.76":[501],"[1.31-2.37],":[502],"comparison":[505],"versus":[508],"showed":[510],"HR":[512,597],"1.34":[514],"[0.999-1.78]).":[515],"diarrhea":[526,588],"(10.4)":[535],"MO3":[537],"(+12.9),":[538],"MO6":[539,560],"(+14.3)":[540],"MO9":[542],"(+12.9)":[543],"bruising":[548],"(10.7)":[558],"(+13.5),":[561],"did":[568],"not":[569],"reach":[570],"other":[575],"any":[578],"time.":[579],"risk":[581],"(TUD,":[596],"2.37":[598],"[1.74-3.23]),":[599],"1.58":[602],"[1.21-2.07])":[603],"1.53":[607],"[1.16-2.02]).":[608],"Conclusions":[609],"treated":[612],"RV,":[616],"rapid":[617],"key":[623],"shortly":[628],"initiation.":[631],"consistently":[635],"later,":[637],"end":[640],"receiving":[645,656],"GIV,":[646],"smaller":[650],"seen":[653],"CIT.":[657],"This":[658,687],"timing":[662],"triple":[668],"combination":[669],"RV/GV":[672],"doublets":[673],"appeared":[674],"be":[676,689],"driven":[677],"by":[678],"GIV.":[686],"should":[688],"considered":[690],"comparing":[692],"efficacy":[693],"combinations":[698]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2025-10-10T00:00:00"}