{"id":"https://openalex.org/W4404962096","doi":"https://doi.org/10.1201/9781003573760-31","title":"Antineoplastic Potential and Other Possible Uses of Swainsonine and Related Compounds","display_name":"Antineoplastic Potential and Other Possible Uses of Swainsonine and Related Compounds","publication_year":2024,"publication_date":"2024-12-03","ids":{"openalex":"https://openalex.org/W4404962096","doi":"https://doi.org/10.1201/9781003573760-31"},"language":"en","primary_location":{"id":"doi:10.1201/9781003573760-31","doi":"https://doi.org/10.1201/9781003573760-31","is_oa":false,"landing_page_url":"https://doi.org/10.1201/9781003573760-31","pdf_url":null,"source":{"id":"https://openalex.org/S4306463075","display_name":"CRC Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320584","host_organization_name":"CRC Press","host_organization_lineage":["https://openalex.org/P4310320584","https://openalex.org/P4310320547"],"host_organization_lineage_names":["CRC Press","Taylor & Francis"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Handbook of Natural Toxins","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4404962233","display_name":"Handbook of Natural Toxins"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040833722","display_name":"Kenneth Olden","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kenneth Olden","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056234429","display_name":"Sandra L. White","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sandra L. White","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113614945","display_name":"Sheila A. Newton","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sheila A. Newton","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072665843","display_name":"Russell J. Molyneux","orcid":"https://orcid.org/0000-0001-6285-8449","observed_orcids":["https://orcid.org/0000-0001-6285-8449"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Russell J. Molyneux","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5000246031","display_name":"Martin James Humphries","orcid":"https://orcid.org/0000-0002-4331-6967","observed_orcids":["https://orcid.org/0000-0002-4331-6967"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Martin J. Humphries","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.48691346,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"575","last_page":"588"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9077000021934509,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9077000021934509,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10835","display_name":"Carbohydrate Chemistry and Synthesis","score":0.05660000070929527,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11385","display_name":"Natural product bioactivities and synthesis","score":0.01489999983459711,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/swainsonine","display_name":"swainsonine","score":1.0},{"id":"https://openalex.org/keywords/anticancer-agents","display_name":"anticancer agents","score":0.8960000276565552},{"id":"https://openalex.org/keywords/glycoprotein-oligosaccharides","display_name":"glycoprotein oligosaccharides","score":0.8709999918937683},{"id":"https://openalex.org/keywords/golgi-apparatus","display_name":"Golgi apparatus","score":0.8360000252723694},{"id":"https://openalex.org/keywords/glycoprotein-processing","display_name":"glycoprotein processing","score":0.7860000133514404},{"id":"https://openalex.org/keywords/carbohydrate-mimetics","display_name":"carbohydrate mimetics","score":0.3569999933242798}],"concepts":[{"id":"https://openalex.org/C2775928797","wikidata":"https://www.wikidata.org/wiki/Q415324","display_name":"Swainsonine","level":2,"score":0.9697934985160828},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.36947837471961975},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3581068515777588},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.3261941075325012},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.32307302951812744},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.25145256519317627},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11685973405838013}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1201/9781003573760-31","doi":"https://doi.org/10.1201/9781003573760-31","is_oa":false,"landing_page_url":"https://doi.org/10.1201/9781003573760-31","pdf_url":null,"source":{"id":"https://openalex.org/S4306463075","display_name":"CRC Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320584","host_organization_name":"CRC Press","host_organization_lineage":["https://openalex.org/P4310320584","https://openalex.org/P4310320547"],"host_organization_lineage_names":["CRC Press","Taylor & Francis"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Handbook of Natural Toxins","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1545603006","https://openalex.org/W2027988055","https://openalex.org/W2029232889","https://openalex.org/W4286001238","https://openalex.org/W2950548677","https://openalex.org/W1570988466","https://openalex.org/W1486483688","https://openalex.org/W2047462034","https://openalex.org/W1605980863","https://openalex.org/W2263298363"],"abstract_inverted_index":{"Swainsonine":[0],"and":[1,41],"related":[2,62],"compounds":[3],"have":[4],"been":[5],"employed":[6],"in":[7,23,58,81],"biomedical":[8],"research":[9],"primarily":[10],"as":[11],"tools":[12],"to":[13,63,69,102],"study":[14],"the":[15,18,64,67,76,98,104],"role":[16],"of":[17,21,66,78,83,85,106,109],"oligosaccharide":[19],"moiety":[20],"glycoproteins":[22,110],"various":[24],"biological":[25],"systems":[26],"(":[27,88,111],"Gibson":[28],"et":[29,34,53,90,113],"al.,":[30,35,54,91,114],"1980":[31],";":[32,39,46,51],"Olden":[33],"1982a":[36],",":[37,44,49],"b":[38],"Schwarz":[40],"Datema,":[42],"1982":[43,92],"1984":[45,48],"Elbein,":[47],"1987":[50,55],"Datema":[52],").":[56,93,116],"Use":[57],"such":[59],"studies":[60],"is":[61],"ability":[65],"drug":[68],"inhibit":[70,103],"Golgi":[71],"a-mannosidase":[72],"II":[73],"activity":[74],"with":[75],"formation":[77],"hybrid":[79],"oligosaccharides":[80,84],"lieu":[82],"complex":[86],"structure":[87],"Tulsiani":[89],"In":[94],"fact,":[95],"swainso-nine":[96],"was":[97],"first":[99],"compound":[100],"shown":[101],"processing":[105],"carbohydrate":[107],"moieties":[108],"Elbein":[112],"1981":[115]},"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2024-12-04T00:00:00"}