{"id":"https://openalex.org/W4404917752","doi":"https://doi.org/10.1016/j.ajt.2024.11.030","title":"Balancing equity and human leukocyte antigen matching in deceased-donor kidney allocation with eplet mismatch","display_name":"Balancing equity and human leukocyte antigen matching in deceased-donor kidney allocation with eplet mismatch","publication_year":2024,"publication_date":"2024-12-02","ids":{"openalex":"https://openalex.org/W4404917752","doi":"https://doi.org/10.1016/j.ajt.2024.11.030","pmid":"https://pubmed.ncbi.nlm.nih.gov/38947023","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11213093"},"language":"en","primary_location":{"id":"doi:10.1016/j.ajt.2024.11.030","doi":"https://doi.org/10.1016/j.ajt.2024.11.030","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ajt.2024.11.030","pdf_url":null,"source":{"id":"https://openalex.org/S182625382","display_name":"American Journal of Transplantation","issn_l":"1600-6135","issn":["1600-6135","1600-6143"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.ajt.2024.11.030","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007618059","display_name":"Michal A. Mankowski","orcid":"https://orcid.org/0000-0002-9923-7408","observed_orcids":["https://orcid.org/0000-0002-9923-7408"]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michal A. Mankowski","raw_affiliation_strings":["Transplant Institute, NYU Langone Health, New York, New York, USA; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, New York, USA. Electronic address: michal.mankowski@nyulangone.com","Transplant Institute, NYU Langone Health, New York, New York; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA. Electronic address: michal.mankowski@nyulangone.com"],"raw_orcid":"https://orcid.org/0000-0002-9923-7408","affiliations":[{"raw_affiliation_string":"Transplant Institute, NYU Langone Health, New York, New York, USA; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, New York, USA. Electronic address: michal.mankowski@nyulangone.com","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]},{"raw_affiliation_string":"Transplant Institute, NYU Langone Health, New York, New York; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA. Electronic address: michal.mankowski@nyulangone.com","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034665415","display_name":"Loren A. Gragert","orcid":"https://orcid.org/0000-0002-5945-6518","observed_orcids":["https://orcid.org/0000-0002-5945-6518"]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Loren Gragert","raw_affiliation_strings":["Division of Biomedical Informatics and Genomics, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA","Division of Biomedical Informatics and Genomics, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA, USA"],"raw_orcid":"https://orcid.org/0000-0002-5945-6518","affiliations":[{"raw_affiliation_string":"Division of Biomedical Informatics and Genomics, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA","institution_ids":["https://openalex.org/I114832834"]},{"raw_affiliation_string":"Division of Biomedical Informatics and Genomics, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA, USA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058430815","display_name":"Brendan J. Keating","orcid":"https://orcid.org/0000-0002-3320-3723","observed_orcids":["https://orcid.org/0000-0002-3320-3723"]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brendan Keating","raw_affiliation_strings":["Transplant Institute, NYU Langone Health, New York, New York, USA; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, New York, USA","Transplant Institute, NYU Langone Health, New York, New York; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0002-3320-3723","affiliations":[{"raw_affiliation_string":"Transplant Institute, NYU Langone Health, New York, New York, USA; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, New York, USA","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]},{"raw_affiliation_string":"Transplant Institute, NYU Langone Health, New York, New York; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081908264","display_name":"Bonnie E. Lonze","orcid":"https://orcid.org/0000-0002-0973-1657","observed_orcids":["https://orcid.org/0000-0002-0973-1657"]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bonnie E. Lonze","raw_affiliation_strings":["Transplant Institute, NYU Langone Health, New York, New York, USA; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, New York, USA","Transplant Institute, NYU Langone Health, New York, New York; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0002-0973-1657","affiliations":[{"raw_affiliation_string":"Transplant Institute, NYU Langone Health, New York, New York, USA; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, New York, USA","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]},{"raw_affiliation_string":"Transplant Institute, NYU Langone Health, New York, New York; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030533822","display_name":"Dorry Lidor Segev","orcid":"https://orcid.org/0000-0002-1924-4801","observed_orcids":["https://orcid.org/0000-0002-1924-4801"]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dorry L. Segev","raw_affiliation_strings":["Transplant Institute, NYU Langone Health, New York, New York, USA; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, New York, USA; Department of Population Health, NYU Grossman School of Medicine, New York, New York, USA","Transplant Institute, NYU Langone Health, New York, New York; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA; Department of Population Health, NYU Grossman School of Medicine, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0002-1924-4801","affiliations":[{"raw_affiliation_string":"Transplant Institute, NYU Langone Health, New York, New York, USA; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, New York, USA; Department of Population Health, NYU Grossman School of Medicine, New York, New York, USA","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]},{"raw_affiliation_string":"Transplant Institute, NYU Langone Health, New York, New York; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA; Department of Population Health, NYU Grossman School of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110536036","display_name":"Robert Montgomery","orcid":"https://orcid.org/0000-0003-2728-4552","observed_orcids":["https://orcid.org/0000-0003-2728-4552"]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Montgomery","raw_affiliation_strings":["Transplant Institute, NYU Langone Health, New York, New York, USA; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, New York, USA; Department of Population Health, NYU Grossman School of Medicine, New York, New York, USA","Transplant Institute, NYU Langone Health, New York, New York; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA; Department of Population Health, NYU Grossman School of Medicine, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0003-2728-4552","affiliations":[{"raw_affiliation_string":"Transplant Institute, NYU Langone Health, New York, New York, USA; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, New York, USA; Department of Population Health, NYU Grossman School of Medicine, New York, New York, USA","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]},{"raw_affiliation_string":"Transplant Institute, NYU Langone Health, New York, New York; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA; Department of Population Health, NYU Grossman School of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033028754","display_name":"Sommer Elizabeth Gentry","orcid":"https://orcid.org/0000-0003-4530-8917","observed_orcids":["https://orcid.org/0000-0003-4530-8917"]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sommer E. Gentry","raw_affiliation_strings":["Transplant Institute, NYU Langone Health, New York, New York, USA; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, New York, USA; Department of Population Health, NYU Grossman School of Medicine, New York, New York, USA","Transplant Institute, NYU Langone Health, New York, New York; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA; Department of Population Health, NYU Grossman School of Medicine, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0003-4530-8917","affiliations":[{"raw_affiliation_string":"Transplant Institute, NYU Langone Health, New York, New York, USA; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, New York, USA; Department of Population Health, NYU Grossman School of Medicine, New York, New York, USA","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]},{"raw_affiliation_string":"Transplant Institute, NYU Langone Health, New York, New York; Department of Surgery, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA; Department of Population Health, NYU Grossman School of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037046702","display_name":"Massimo Mangiola","orcid":"https://orcid.org/0000-0002-5406-4005","observed_orcids":["https://orcid.org/0000-0002-5406-4005"]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Massimo Mangiola","raw_affiliation_strings":["Transplant Institute, NYU Langone Health, New York, New York, USA","Transplant Institute, NYU Langone Health, New York, New York"],"raw_orcid":"https://orcid.org/0000-0002-5406-4005","affiliations":[{"raw_affiliation_string":"Transplant Institute, NYU Langone Health, New York, New York, USA","institution_ids":["https://openalex.org/I4210086933"]},{"raw_affiliation_string":"Transplant Institute, NYU Langone Health, New York, New York","institution_ids":["https://openalex.org/I4210086933"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5007618059"],"corresponding_institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"],"apc_list":{"value":4300,"currency":"USD","value_usd":4300},"apc_paid":{"value":4300,"currency":"USD","value_usd":4300},"fwci":8.5047,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.98639456,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"25","issue":"6","first_page":"1226","last_page":"1234"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.9330999851226807,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.9330999851226807,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11163","display_name":"Organ Donation and Transplantation","score":0.06260000169277191,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hla-matching","display_name":"HLA matching","score":0.6710000038146973},{"id":"https://openalex.org/keywords/eplet-mismatch","display_name":"eplet mismatch","score":0.8619999885559082},{"id":"https://openalex.org/keywords/deceased-donor-kidney-allocation","display_name":"deceased donor kidney allocation","score":0.9350000023841858},{"id":"https://openalex.org/keywords/racial-disparities","display_name":"racial disparities","score":0.875},{"id":"https://openalex.org/keywords/hla-dr","display_name":"HLA-DR","score":0.5040000081062317},{"id":"https://openalex.org/keywords/hla-dq","display_name":"HLA-DQ","score":0.9980000257492065},{"id":"https://openalex.org/keywords/hla-dq-mismatch","display_name":"HLA-DQ mismatch","score":0.492000013589859},{"id":"https://openalex.org/keywords/risk-stratification","display_name":"risk stratification","score":0.6610000133514404}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8088707327842712},{"id":"https://openalex.org/C199728807","wikidata":"https://www.wikidata.org/wiki/Q2578557","display_name":"Equity (law)","level":2,"score":0.6319798827171326},{"id":"https://openalex.org/C188280979","wikidata":"https://www.wikidata.org/wiki/Q911125","display_name":"Human leukocyte antigen","level":3,"score":0.531125545501709},{"id":"https://openalex.org/C165064840","wikidata":"https://www.wikidata.org/wiki/Q1321061","display_name":"Matching (statistics)","level":2,"score":0.5205886960029602},{"id":"https://openalex.org/C2994498544","wikidata":"https://www.wikidata.org/wiki/Q740909","display_name":"Kidney transplant","level":4,"score":0.421994686126709},{"id":"https://openalex.org/C2780303639","wikidata":"https://www.wikidata.org/wiki/Q740909","display_name":"Kidney transplantation","level":3,"score":0.4192322790622711},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27128395438194275},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.24875548481941223},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.14909237623214722},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.09456139802932739},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.07052448391914368},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1016/j.ajt.2024.11.030","doi":"https://doi.org/10.1016/j.ajt.2024.11.030","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ajt.2024.11.030","pdf_url":null,"source":{"id":"https://openalex.org/S182625382","display_name":"American Journal of Transplantation","issn_l":"1600-6135","issn":["1600-6135","1600-6143"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Transplantation","raw_type":"journal-article"},{"id":"doi:10.1101/2024.06.13.23290644","doi":"https://doi.org/10.1101/2024.06.13.23290644","is_oa":false,"landing_page_url":"https://doi.org/10.1101/2024.06.13.23290644","pdf_url":null,"source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},{"id":"pmid:38947023","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38947023","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"medRxiv : the preprint server for health sciences","raw_type":"Journal Article"},{"id":"pmid:39631566","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39631566","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11213093","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11213093","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.ajt.2024.11.030","doi":"https://doi.org/10.1016/j.ajt.2024.11.030","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ajt.2024.11.030","pdf_url":null,"source":{"id":"https://openalex.org/S182625382","display_name":"American Journal of Transplantation","issn_l":"1600-6135","issn":["1600-6135","1600-6143"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Transplantation","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"},{"id":"https://metadata.un.org/sdg/10","score":0.8974000215530396,"display_name":"Reduced inequalities"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1165457822","display_name":"A prospective clinical trial of immunosuppression reduction in recipients of low eplet mismatched renal allografts: the kidney for life initiative","funder_award_id":"R34AI177209","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G2572461085","display_name":"Patient Oriented Research in Solid Organ Transplantation","funder_award_id":"K24AI144954","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G8039241462","display_name":"MHC and KIR Sequencing and Association Analyses in the iGeneTRAiN Studies","funder_award_id":"U01AI152960","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G9000860828","display_name":"Continuous allocation score design for guaranteeing equity and reducing discards in kidney and liver transplantation","funder_award_id":"R01DK132395","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G9000887015","display_name":"HLA Immunogenetics and kidney allograft outcomes","funder_award_id":"R01AI173095","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G9000909356","display_name":"Increasing Equity and Utility in Deceased Donor Kidney Allocation with HLA Molecular Matching","funder_award_id":"R01DK139240","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320306085","display_name":"U.S. Department of Health and Human Services","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W1513424590","https://openalex.org/W1545464200","https://openalex.org/W2041482624","https://openalex.org/W2075067486","https://openalex.org/W2127707359","https://openalex.org/W2142966586","https://openalex.org/W2160607034","https://openalex.org/W2232979758","https://openalex.org/W2290774306","https://openalex.org/W2323204318","https://openalex.org/W2522656570","https://openalex.org/W2739465434","https://openalex.org/W2790743418","https://openalex.org/W2885830535","https://openalex.org/W2900181891","https://openalex.org/W2908670684","https://openalex.org/W2914380630","https://openalex.org/W2980095467","https://openalex.org/W2983017701","https://openalex.org/W2988332685","https://openalex.org/W3013022634","https://openalex.org/W3015945674","https://openalex.org/W3048196734","https://openalex.org/W3083160147","https://openalex.org/W3136072219","https://openalex.org/W3158943687","https://openalex.org/W3163949076","https://openalex.org/W3179084811","https://openalex.org/W3183755099","https://openalex.org/W4200201077","https://openalex.org/W4200449167","https://openalex.org/W4210392069","https://openalex.org/W4213372668","https://openalex.org/W4220914061","https://openalex.org/W4297248817","https://openalex.org/W4315630530","https://openalex.org/W4315631927"],"related_works":["https://openalex.org/W2980095467","https://openalex.org/W7118969380","https://openalex.org/W2017383623","https://openalex.org/W3179084811","https://openalex.org/W4412852063","https://openalex.org/W4405696764","https://openalex.org/W2444120191","https://openalex.org/W3048196734","https://openalex.org/W1977259013","https://openalex.org/W2075351724"],"abstract_inverted_index":{"ABSTRACT":[0],"Background":[1],"Prioritization":[2],"of":[3,54,82,93,103,122,146,179,192,208,229,254],"HLA":[4,61,138,184],"antigen-level":[5,230],"matching":[6,30,263],"in":[7,169,199,219,264],"the":[8,64,79,83,91,144,159,177,206,226,255,278],"US":[9,85,220],"kidney":[10,222,265],"allocation":[11,170,267],"system":[12],"intends":[13],"to":[14,37,42,72,158,194,225,242,245,277],"improve":[15,38,270],"post-transplant":[16],"survival":[17],"but":[18],"causes":[19],"racial":[20,173,215,239,274],"disparities":[21,174,218,240,275],"and":[22,117,128,140,175,216,249,272],"thus":[23],"has":[24,34],"been":[25,35],"substantially":[26],"de-emphasized.":[27],"Recently,":[28],"molecular":[29,196,211],"based":[31,77],"on":[32,78,214],"eplets":[33,48,193],"found":[36],"risk":[39,258],"stratification":[40],"compared":[41,224,244,276],"antigen":[43,126,139,162,247,280],"matching.":[44,281],"Methods":[45],"To":[46],"assign":[47],"unambiguously,":[49],"we":[50,89],"utilized":[51],"a":[52,165,251],"cohort":[53],"5193":[55],"individuals":[56],"with":[57,106,124],"high":[58],"resolution":[59,183],"allele-level":[60],"genotypes":[62],"from":[63],"National":[65],"Kidney":[66],"Registry.":[67],"Using":[68],"repeated":[69],"random":[70],"sampling":[71],"simulate":[73],"donor-recipient":[74],"genotype":[75],"pairings":[76],"ethnic":[80,154,217],"composition":[81],"historical":[84],"deceased":[86,185],"donor":[87,186],"pool,":[88],"profiled":[90],"percentage":[92,102,121,145,178],"well-matched":[94,104,147,180],"donors":[95,105,123,148],"for":[96,115,133],"candidates":[97,119],"by":[98],"ethnicity.":[99],"Results":[100],"The":[101,233],"zero-DR/DQ":[107,166],"eplet":[108,141,167,235,262],"mismatch":[109,142,168,197,212,236,248],"was":[110,149],"3-fold":[111,243],"less":[112,130],"racially":[113,131],"disparate":[114,132],"Black":[116],"Asian":[118],"than":[120],"zero-ABDR":[125,161],"mismatches,":[127],"2-fold":[129],"Latino":[134],"candidates.":[135],"For":[136],"other":[137],"thresholds,":[143],"more":[150],"similar":[151],"across":[152],"candidate":[153],"groups.":[155],"Conclusions":[156],"Compared":[157],"current":[160,227,279],"mismatch,":[163],"prioritizing":[164,209],"would":[171,188],"decrease":[172],"increase":[176],"donors.":[181,259],"High":[182],"genotyping":[187],"enable":[189],"unambiguous":[190],"assignment":[191],"operationalize":[195],"metrics":[198],"allocation.":[200],"Key":[201],"Points":[202],"Question":[203],"What":[204],"is":[205],"impact":[207],"low":[210],"transplants":[213],"deceased-donor":[221],"allocation,":[223],"prioritization":[228],"matching?":[231],"Findings":[232],"lowest-risk":[234,246],"approach":[237],"decreases":[238],"up":[241],"identifies":[250],"larger":[252],"number":[253],"lowest":[256],"allo-immune":[257],"Meaning":[260],"Prioritizing":[261],"transplant":[266],"could":[268],"both":[269],"outcomes":[271],"reduce":[273]},"counts_by_year":[{"year":2026,"cited_by_count":12},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-12-03T00:00:00"}