{"id":"https://openalex.org/W4404885871","doi":"https://doi.org/10.1016/j.vaccine.2024.126573","title":"Association of baseline cytokines with antibody concentrations after diphtheria-tetanus-acellular pertussis booster vaccination in Finnish children","display_name":"Association of baseline cytokines with antibody concentrations after diphtheria-tetanus-acellular pertussis booster vaccination in Finnish children","publication_year":2024,"publication_date":"2024-11-29","ids":{"openalex":"https://openalex.org/W4404885871","doi":"https://doi.org/10.1016/j.vaccine.2024.126573","pmid":"https://pubmed.ncbi.nlm.nih.gov/39616006"},"language":"en","primary_location":{"id":"doi:10.1016/j.vaccine.2024.126573","doi":"https://doi.org/10.1016/j.vaccine.2024.126573","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.vaccine.2024.126573","pdf_url":null,"source":{"id":"https://openalex.org/S27359860","display_name":"Vaccine","issn_l":"0264-410X","issn":["0264-410X","1873-2518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.vaccine.2024.126573","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5114908963","display_name":"Denise Anabe","orcid":"https://orcid.org/0009-0007-1686-4910","observed_orcids":["https://orcid.org/0009-0007-1686-4910"]},"institutions":[{"id":"https://openalex.org/I155660961","display_name":"University of Turku","ror":"https://ror.org/05vghhr25","country_code":"FI","type":"education","lineage":["https://openalex.org/I155660961"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Denise Anabe","raw_affiliation_strings":["Institute of Biomedicine, Research Centre for Infections and Immunity, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland. Electronic address: daanab@utu.fi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedicine, Research Centre for Infections and Immunity, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland. Electronic address: daanab@utu.fi","institution_ids":["https://openalex.org/I155660961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042296530","display_name":"Johanna T. Ter\u00e4sj\u00e4rvi","orcid":"https://orcid.org/0009-0008-8209-4384","observed_orcids":["https://orcid.org/0009-0008-8209-4384"]},"institutions":[{"id":"https://openalex.org/I155660961","display_name":"University of Turku","ror":"https://ror.org/05vghhr25","country_code":"FI","type":"education","lineage":["https://openalex.org/I155660961"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Johanna T. Ter\u00e4sj\u00e4rvi","raw_affiliation_strings":["Institute of Biomedicine, Research Centre for Infections and Immunity, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland. Electronic address: johter@utu.fi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedicine, Research Centre for Infections and Immunity, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland. Electronic address: johter@utu.fi","institution_ids":["https://openalex.org/I155660961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023543427","display_name":"Alex\u2010Mikael Barkoff","orcid":"https://orcid.org/0000-0003-0742-1580","observed_orcids":["https://orcid.org/0000-0003-0742-1580"]},"institutions":[{"id":"https://openalex.org/I155660961","display_name":"University of Turku","ror":"https://ror.org/05vghhr25","country_code":"FI","type":"education","lineage":["https://openalex.org/I155660961"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Alex-Mikael Barkoff","raw_affiliation_strings":["Institute of Biomedicine, Research Centre for Infections and Immunity, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland. Electronic address: ambark@utu.fi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedicine, Research Centre for Infections and Immunity, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland. Electronic address: ambark@utu.fi","institution_ids":["https://openalex.org/I155660961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065068123","display_name":"Aapo Knuutila","orcid":"https://orcid.org/0000-0003-0622-5043","observed_orcids":["https://orcid.org/0000-0003-0622-5043"]},"institutions":[{"id":"https://openalex.org/I155660961","display_name":"University of Turku","ror":"https://ror.org/05vghhr25","country_code":"FI","type":"education","lineage":["https://openalex.org/I155660961"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Aapo Knuutila","raw_affiliation_strings":["Institute of Biomedicine, Research Centre for Infections and Immunity, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland; Department of Life Technologies, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland. Electronic address: aajukn@utu.fi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedicine, Research Centre for Infections and Immunity, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland; Department of Life Technologies, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland. Electronic address: aajukn@utu.fi","institution_ids":["https://openalex.org/I155660961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113904414","display_name":"Bernd Pape","orcid":"https://orcid.org/0009-0001-7769-1861","observed_orcids":["https://orcid.org/0009-0001-7769-1861"]},"institutions":[{"id":"https://openalex.org/I155660961","display_name":"University of Turku","ror":"https://ror.org/05vghhr25","country_code":"FI","type":"education","lineage":["https://openalex.org/I155660961"]},{"id":"https://openalex.org/I2801970007","display_name":"Turku University Hospital","ror":"https://ror.org/05dbzj528","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2801970007","https://openalex.org/I4210127022"]},{"id":"https://openalex.org/I79765343","display_name":"University of Vaasa","ror":"https://ror.org/03769b225","country_code":"FI","type":"education","lineage":["https://openalex.org/I79765343"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Bernd Pape","raw_affiliation_strings":["Department of Biostatistics, University of Turku and Turku University Hospital, 20520 Turku, Finland; Department of Mathematics and Statistics, University of Vaasa, 65101 Vaasa, Finland. Electronic address: bernd.pape@utu.fi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, University of Turku and Turku University Hospital, 20520 Turku, Finland; Department of Mathematics and Statistics, University of Vaasa, 65101 Vaasa, Finland. Electronic address: bernd.pape@utu.fi","institution_ids":["https://openalex.org/I155660961","https://openalex.org/I2801970007","https://openalex.org/I79765343"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056832467","display_name":"Pieter G. M. van Gageldonk","orcid":"https://orcid.org/0000-0003-2753-9674","observed_orcids":["https://orcid.org/0000-0003-2753-9674"]},"institutions":[{"id":"https://openalex.org/I4210104433","display_name":"National Institute for Public Health and the Environment","ror":"https://ror.org/01cesdt21","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210104433"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Pieter van Gageldonk","raw_affiliation_strings":["National Institute for Public Health and the Environment, Centre for Infectious Disease Control, Bilthoven, the Netherlands. Electronic address: pieter.van.gageldonk@rivm.nl"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute for Public Health and the Environment, Centre for Infectious Disease Control, Bilthoven, the Netherlands. Electronic address: pieter.van.gageldonk@rivm.nl","institution_ids":["https://openalex.org/I4210104433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042910491","display_name":"Anne\u2010Marie Buisman","orcid":"https://orcid.org/0000-0001-5085-7844","observed_orcids":["https://orcid.org/0000-0001-5085-7844"]},"institutions":[{"id":"https://openalex.org/I4210104433","display_name":"National Institute for Public Health and the Environment","ror":"https://ror.org/01cesdt21","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210104433"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Annemarie Buisman","raw_affiliation_strings":["National Institute for Public Health and the Environment, Centre for Infectious Disease Control, Bilthoven, the Netherlands. Electronic address: annemarie.buisman@rivm.nl"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute for Public Health and the Environment, Centre for Infectious Disease Control, Bilthoven, the Netherlands. Electronic address: annemarie.buisman@rivm.nl","institution_ids":["https://openalex.org/I4210104433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070691873","display_name":"Jussi Mertsola","orcid":"https://orcid.org/0000-0002-7746-3949","observed_orcids":["https://orcid.org/0000-0002-7746-3949"]},"institutions":[{"id":"https://openalex.org/I2801970007","display_name":"Turku University Hospital","ror":"https://ror.org/05dbzj528","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2801970007","https://openalex.org/I4210127022"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Jussi Mertsola","raw_affiliation_strings":["Department of Pediatric and Adolescent Medicine, Turku University Hospital, Turku, Finland; (J,M.). Electronic address: jusmer@utu.fi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric and Adolescent Medicine, Turku University Hospital, Turku, Finland; (J,M.). Electronic address: jusmer@utu.fi","institution_ids":["https://openalex.org/I2801970007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013185546","display_name":"Qiushui He","orcid":"https://orcid.org/0000-0002-1334-6065","observed_orcids":["https://orcid.org/0000-0002-1334-6065"]},"institutions":[{"id":"https://openalex.org/I155660961","display_name":"University of Turku","ror":"https://ror.org/05vghhr25","country_code":"FI","type":"education","lineage":["https://openalex.org/I155660961"]}],"countries":["FI"],"is_corresponding":true,"raw_author_name":"Qiushui He","raw_affiliation_strings":["Institute of Biomedicine, Research Centre for Infections and Immunity, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland; InFLAMES Research Flagship Centre, University of Turku, Turku 20520, Finland. Electronic address: qiushui.he@utu.fi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedicine, Research Centre for Infections and Immunity, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland; InFLAMES Research Flagship Centre, University of Turku, Turku 20520, Finland. Electronic address: qiushui.he@utu.fi","institution_ids":["https://openalex.org/I155660961"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5013185546"],"corresponding_institution_ids":["https://openalex.org/I155660961"],"apc_list":{"value":3650,"currency":"USD","value_usd":3650},"apc_paid":{"value":3650,"currency":"USD","value_usd":3650},"fwci":0.776,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.7141129,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"44","issue":null,"first_page":"126573","last_page":"126573"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":0.951200008392334,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":0.951200008392334,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12499","display_name":"Diphtheria, Corynebacterium, and Tetanus","score":0.03830000013113022,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13410","display_name":"Immune responses and vaccinations","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diphtheria-tetanus-acellular-pertussis-vaccine","display_name":"diphtheria-tetanus-acellular pertussis vaccine","score":0.9390000104904175},{"id":"https://openalex.org/keywords/vaccine-antibody-response","display_name":"vaccine antibody response","score":0.7039999961853027},{"id":"https://openalex.org/keywords/age-differences","display_name":"age differences","score":0.4169999957084656},{"id":"https://openalex.org/keywords/il-17f","display_name":"IL-17F","score":0.6690000295639038},{"id":"https://openalex.org/keywords/il-10","display_name":"IL-10","score":0.7670000195503235},{"id":"https://openalex.org/keywords/il-13","display_name":"IL-13","score":0.8920000195503235},{"id":"https://openalex.org/keywords/il-5","display_name":"IL-5","score":0.8650000095367432},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.8820000290870667},{"id":"https://openalex.org/keywords/interleukin-2","display_name":"interleukin-2","score":0.8880000114440918},{"id":"https://openalex.org/keywords/pertussis-toxin","display_name":"pertussis toxin","score":0.4059999883174896},{"id":"https://openalex.org/keywords/filamentous-hemagglutinin","display_name":"filamentous hemagglutinin","score":0.9629999995231628}],"concepts":[{"id":"https://openalex.org/C2780572238","wikidata":"https://www.wikidata.org/wiki/Q134649","display_name":"Diphtheria","level":3,"score":0.8201966285705566},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7343977093696594},{"id":"https://openalex.org/C2779841045","wikidata":"https://www.wikidata.org/wiki/Q47790","display_name":"Tetanus","level":3,"score":0.6394258737564087},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.5959091782569885},{"id":"https://openalex.org/C203165030","wikidata":"https://www.wikidata.org/wiki/Q741745","display_name":"Booster (rocketry)","level":2,"score":0.5328683853149414},{"id":"https://openalex.org/C12590561","wikidata":"https://www.wikidata.org/wiki/Q2920497","display_name":"Booster dose","level":4,"score":0.5314841270446777},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.48450347781181335},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.46803003549575806},{"id":"https://openalex.org/C2779214499","wikidata":"https://www.wikidata.org/wiki/Q134859","display_name":"Whooping cough","level":3,"score":0.45824238657951355},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.40960705280303955},{"id":"https://openalex.org/C2780801004","wikidata":"https://www.wikidata.org/wiki/Q1415366","display_name":"Immunization","level":3,"score":0.2638193964958191},{"id":"https://openalex.org/C1276947","wikidata":"https://www.wikidata.org/wiki/Q333","display_name":"Astronomy","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000907","descriptor_name":"Antibodies, Bacterial","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D000907","descriptor_name":"Antibodies, Bacterial","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005387","descriptor_name":"Finland","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007117","descriptor_name":"Immunization, Secondary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014917","descriptor_name":"Whooping Cough","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D014917","descriptor_name":"Whooping Cough","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D022681","descriptor_name":"Diphtheria-Tetanus-acellular Pertussis Vaccines","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D022681","descriptor_name":"Diphtheria-Tetanus-acellular Pertussis Vaccines","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057134","descriptor_name":"Antibodies, Neutralizing","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D057134","descriptor_name":"Antibodies, Neutralizing","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1016/j.vaccine.2024.126573","doi":"https://doi.org/10.1016/j.vaccine.2024.126573","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.vaccine.2024.126573","pdf_url":null,"source":{"id":"https://openalex.org/S27359860","display_name":"Vaccine","issn_l":"0264-410X","issn":["0264-410X","1873-2518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"journal-article"},{"id":"pmid:39616006","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39616006","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"Journal Article"},{"id":"pmh:oai:utupub.fi:11111/51649","doi":null,"is_oa":true,"landing_page_url":"https://www.utupub.fi/handle/11111/51649","pdf_url":"https://www.utupub.fi/bitstreams/4138371a-3769-48bf-abb6-3f45e6c6a423/download","source":{"id":"https://openalex.org/S4306402470","display_name":"UTUPub (University of Turku)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I155660961","host_organization_name":"University of Turku","host_organization_lineage":["https://openalex.org/I155660961"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://www.utupub.fi/handle/10024/193548","raw_type":null},{"id":"pmh:oai:www.utupub.fi:10024/193548","doi":null,"is_oa":true,"landing_page_url":"https://www.utupub.fi/handle/10024/193548","pdf_url":"https://www.utupub.fi/bitstream/10024/193548/1/1-s2.0-S0264410X24012556-main.pdf","source":{"id":"https://openalex.org/S4306402470","display_name":"UTUPub (University of Turku)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I155660961","host_organization_name":"University of Turku","host_organization_lineage":["https://openalex.org/I155660961"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"pmh:oai:osuva.uwasa.fi:10024/19372","doi":null,"is_oa":true,"landing_page_url":"https://osuva.uwasa.fi/handle/10024/19372","pdf_url":null,"source":{"id":"https://openalex.org/S4306400974","display_name":"Osuva (University of Vaasa)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79765343","host_organization_name":"University of Vaasa","host_organization_lineage":["https://openalex.org/I79765343"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"2-s2.0-85210729799","raw_type":"article"},{"id":"pmh:oai:osuva.uwasa.fi:11111/3274","doi":null,"is_oa":true,"landing_page_url":"https://osuva.uwasa.fi/items/a70c0955-392a-4668-840b-56d08d29c8b6","pdf_url":null,"source":{"id":"https://openalex.org/S4306400974","display_name":"Osuva (University of Vaasa)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79765343","host_organization_name":"University of Vaasa","host_organization_lineage":["https://openalex.org/I79765343"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://osuva.uwasa.fi/handle/10024/19372","raw_type":"article"},{"id":"pmh:oai:rivm.openrepository.com:10029/627942","doi":null,"is_oa":false,"landing_page_url":"https://rivm.openrepository.com/handle/10029/627942","pdf_url":null,"source":{"id":"https://openalex.org/S4306401814","display_name":"Rivm Repository (Netherlands National Institute for Public Health and the Environment)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210104433","host_organization_name":"National Institute for Public Health and the Environment","host_organization_lineage":["https://openalex.org/I4210104433"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Netherlands","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1016/j.vaccine.2024.126573","doi":"https://doi.org/10.1016/j.vaccine.2024.126573","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.vaccine.2024.126573","pdf_url":null,"source":{"id":"https://openalex.org/S27359860","display_name":"Vaccine","issn_l":"0264-410X","issn":["0264-410X","1873-2518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2388197598","display_name":null,"funder_award_id":"115910","funder_id":"https://openalex.org/F4320326631","funder_display_name":"Innovative Medicines Initiative"},{"id":"https://openalex.org/G2593929496","display_name":null,"funder_award_id":"26006205","funder_id":"https://openalex.org/F4320324052","funder_display_name":"Tampereen Tuberkuloosis\u00e4\u00e4ti\u00f6"},{"id":"https://openalex.org/G6088479093","display_name":"PERtussIS COrrelates of Protection Europe - Sofia ref.: 115910","funder_award_id":"115910","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G8724033833","display_name":null,"funder_award_id":"240045","funder_id":"https://openalex.org/F4320324052","funder_display_name":"Tampereen Tuberkuloosis\u00e4\u00e4ti\u00f6"}],"funders":[{"id":"https://openalex.org/F4320306137","display_name":"Bill and Melinda Gates Foundation","ror":"https://ror.org/0456r8d26"},{"id":"https://openalex.org/F4320314178","display_name":"European Federation of Pharmaceutical Industries and Associations","ror":"https://ror.org/00g1x4v36"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320323760","display_name":"Sigrid Jus\u00e9liuksen S\u00e4\u00e4ti\u00f6","ror":"https://ror.org/00ckakm23"},{"id":"https://openalex.org/F4320324052","display_name":"Tampereen Tuberkuloosis\u00e4\u00e4ti\u00f6","ror":"https://ror.org/00yp3hb50"},{"id":"https://openalex.org/F4320326631","display_name":"Innovative Medicines Initiative","ror":"https://ror.org/019af4n30"},{"id":"https://openalex.org/F4320335254","display_name":"Horizon 2020","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W1679061143","https://openalex.org/W1914370328","https://openalex.org/W1981597823","https://openalex.org/W1991348178","https://openalex.org/W2000119111","https://openalex.org/W2012706589","https://openalex.org/W2041647537","https://openalex.org/W2070844733","https://openalex.org/W2074128804","https://openalex.org/W2110410613","https://openalex.org/W2144276864","https://openalex.org/W2296358134","https://openalex.org/W2397263404","https://openalex.org/W2509096421","https://openalex.org/W2513671461","https://openalex.org/W2518536270","https://openalex.org/W2523416377","https://openalex.org/W2772231960","https://openalex.org/W2896080762","https://openalex.org/W2921553057","https://openalex.org/W2953736961","https://openalex.org/W2968399532","https://openalex.org/W2972642601","https://openalex.org/W2981100201","https://openalex.org/W3013397538","https://openalex.org/W3015851459","https://openalex.org/W3038213731","https://openalex.org/W3134638020","https://openalex.org/W3161407471","https://openalex.org/W3172114503","https://openalex.org/W3193100538","https://openalex.org/W4220842956","https://openalex.org/W4281293568","https://openalex.org/W4307716642","https://openalex.org/W4386772660","https://openalex.org/W6769037663","https://openalex.org/W6795359665"],"related_works":["https://openalex.org/W1992685435","https://openalex.org/W7099133516","https://openalex.org/W2028152425","https://openalex.org/W4250229633","https://openalex.org/W1970784288","https://openalex.org/W1978665328","https://openalex.org/W3129817134","https://openalex.org/W7161235543","https://openalex.org/W2010328305","https://openalex.org/W4413117232"],"abstract_inverted_index":{"BACKGROUND:":[0],"Despite":[1],"extensive":[2],"vaccinations,":[3],"pertussis":[4,78,297],"remains":[5],"endemic":[6],"and":[7,64,91,106,123,132,153,184,208,212,252,264,279,303],"epidemic":[8],"in":[9,25,204,217,226,261,274,296,301,307],"multiple":[10],"countries.":[11],"The":[12,128],"persistence":[13],"of":[14,33,115,130,142,148,233,248,293,321],"cases":[15],"can":[16],"be":[17,314],"partly":[18],"attributed":[19],"to":[20,42,156,219],"the":[21,31,110,231,311,319],"significant":[22],"individual":[23],"variation":[24],"vaccine":[26],"responses.":[27],"This":[28],"study":[29],"evaluated":[30],"association":[32],"baseline":[34,134,246],"cytokines":[35,135,295],"(before":[36],"booster":[37,298],"vaccination)":[38],"on":[39],"antibody":[40,259,299],"concentrations":[41,114,260,278,300],"Tdap-vaccine":[43],"antigens.":[44],"METHODS:":[45],"Healthy":[46],"Finnish":[47],"children":[48,143,205,262,302],"(7-10y,":[49],"n":[50,55,61,68],"=":[51,56,62,69],"36),":[52],"adolescents":[53,157,220,275],"(11-15y,":[54],"37),":[57],"young":[58,170,209,280],"adults":[59,66,171,186,214,281],"(20-34y,":[60],"25),":[63],"older":[65,185,213],"(60-70y,":[67],"23)":[70],"received":[71],"a":[72,145,201,290],"Tdap3-IPV":[73],"booster.":[74,111],"Serum":[75],"antibodies":[76,100],"against":[77,268],"toxin":[79],"(PT),":[80],"filamentous":[81],"hemagglutinin":[82],"(FHA),":[83],"pertactin":[84],"(Prn),":[85],"fimbriae":[86],"2/3,":[87],"diphtheria":[88],"toxoid":[89,93],"(DT),":[90],"tetanus":[92],"(TT),":[94],"as":[95,97,318],"well":[96],"PT":[98],"neutralizing":[99],"were":[101,125,255,272],"measured":[102],"before,":[103],"one":[104,107],"month,":[105],"year":[108],"after":[109,265],"Baseline":[112],"serum":[113],"IFN-\u03b3,":[116,249],"IL-2,":[117,250],"IL-5,":[118,150],"IL-10,":[119,151,161,175,190,251],"IL-13,":[120,152,164,178,193],"IL-17":[121,235,253],"A":[122,236,240,254],"IL-17F":[124,154],"determined.":[126],"RESULTS:":[127],"proportion":[129,147,232],"detectable":[131,149,234],"undetectable":[133,225,245],"varied":[136],"between":[137],"age":[138,228],"groups":[139,229],"58.3":[140],"%":[141],"had":[144,200],"higher":[146,258],"compared":[155],"(IL-5,":[158,172,187],"37.8":[159],"%;":[160,163,166,174,177,180,189,192,195],"48.6":[162,165],"IL-17F,":[167,181,196],"37.7":[168],"%),":[169,183],"36.0":[173,179],"28.0":[176],"44.0":[182],"26.1":[188],"21.7":[191],"39.1":[194],"30.4":[197],"%).":[198,222],"IFN-\u03b3":[199],"lower":[202],"detectability":[203],"(44.4":[206],"%)":[207,211,216],"(40.0":[210],"(39.1":[215],"contrast":[218],"(62.2":[221],"IL-2":[223],"was":[224],"all":[227],"while":[230],"decreased":[237],"with":[238,257,316],"age.":[239],"mixed":[241],"model":[242],"showed":[243],"that":[244],"levels":[247],"associated":[256],"before":[263],"vaccination,":[266],"particularly":[267],"PT.":[269],"Positive":[270],"associations":[271],"observed":[273],"for":[276,282],"anti-TT":[277],"anti-FHA":[283],"IgA":[284],"concentrations.":[285],"CONCLUSION:":[286],"These":[287],"findings":[288],"indicate":[289],"possible":[291],"role":[292],"existing":[294],"warrant":[304],"further":[305],"studies":[306],"different":[308],"populations.":[309],"However,":[310],"results":[312],"should":[313],"interpreted":[315],"caution":[317],"number":[320],"subjects":[322],"is":[323],"limited.":[324]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2024-12-01T00:00:00"}