{"id":"https://openalex.org/W4404842148","doi":"https://doi.org/10.1002/9781119654629.ch29","title":"Antimicrobial Therapy in Beef Cattle","display_name":"Antimicrobial Therapy in Beef Cattle","publication_year":2024,"publication_date":"2024-11-29","ids":{"openalex":"https://openalex.org/W4404842148","doi":"https://doi.org/10.1002/9781119654629.ch29"},"language":"en","primary_location":{"id":"doi:10.1002/9781119654629.ch29","doi":"https://doi.org/10.1002/9781119654629.ch29","is_oa":true,"landing_page_url":"https://doi.org/10.1002/9781119654629.ch29","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/9781119654629.ch29","source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrobial Therapy in Veterinary Medicine","raw_type":"other"},"volume":{"id":"https://openalex.org/W1571171681","display_name":"Antimicrobial Therapy in Veterinary Medicine"},"type":"other","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/9781119654629.ch29","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008909573","display_name":"Michael D. Apley","orcid":"https://orcid.org/0000-0003-1108-1953","observed_orcids":["https://orcid.org/0000-0003-1108-1953"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael D. Apley","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086104305","display_name":"Brian V. Lubbers","orcid":"https://orcid.org/0000-0001-6589-3274","observed_orcids":["https://orcid.org/0000-0001-6589-3274"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brian V. Lubbers","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5061078306","display_name":"Nora F. D. Schrag","orcid":"https://orcid.org/0000-0003-4678-8692","observed_orcids":["https://orcid.org/0000-0003-4678-8692"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nora D. Schrag","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"611","last_page":"633"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.5034000277519226,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.5034000277519226,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13791","display_name":"Veterinary medicine and infectious diseases","score":0.2816999852657318,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10486","display_name":"Salmonella and Campylobacter epidemiology","score":0.05730000138282776,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antimicrobial-therapy","display_name":"antimicrobial therapy","score":0.8410000205039978},{"id":"https://openalex.org/keywords/beef-cattle","display_name":"beef cattle","score":0.953000009059906},{"id":"https://openalex.org/keywords/antimicrobial-resistance","display_name":"antimicrobial resistance","score":0.9980000257492065},{"id":"https://openalex.org/keywords/extra-label-drug-use","display_name":"extra-label drug use","score":0.8460000157356262},{"id":"https://openalex.org/keywords/cryptosporidium-parvum","display_name":"Cryptosporidium parvum","score":0.9760000109672546},{"id":"https://openalex.org/keywords/calves","display_name":"calves","score":0.6729999780654907},{"id":"https://openalex.org/keywords/lasalocid","display_name":"lasalocid","score":0.8899999856948853},{"id":"https://openalex.org/keywords/paromomycin","display_name":"paromomycin","score":0.9419999718666077},{"id":"https://openalex.org/keywords/azithromycin","display_name":"azithromycin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/clarithromycin","display_name":"clarithromycin","score":1.0},{"id":"https://openalex.org/keywords/oocyst-shedding","display_name":"oocyst shedding","score":0.9190000295639038},{"id":"https://openalex.org/keywords/cattle-diseases","display_name":"cattle diseases","score":0.43299999833106995}],"concepts":[{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.7269347906112671},{"id":"https://openalex.org/C2780505807","wikidata":"https://www.wikidata.org/wiki/Q1208989","display_name":"Beef cattle","level":2,"score":0.680497407913208},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.35918962955474854},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30030035972595215},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.13984030485153198}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/9781119654629.ch29","doi":"https://doi.org/10.1002/9781119654629.ch29","is_oa":true,"landing_page_url":"https://doi.org/10.1002/9781119654629.ch29","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/9781119654629.ch29","source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrobial Therapy in Veterinary Medicine","raw_type":"other"}],"best_oa_location":{"id":"doi:10.1002/9781119654629.ch29","doi":"https://doi.org/10.1002/9781119654629.ch29","is_oa":true,"landing_page_url":"https://doi.org/10.1002/9781119654629.ch29","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/9781119654629.ch29","source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antimicrobial Therapy in Veterinary Medicine","raw_type":"other"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6240000128746033},{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.5666999816894531}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4404842148.pdf","grobid_xml":"https://content.openalex.org/works/W4404842148.grobid-xml"},"referenced_works_count":57,"referenced_works":["https://openalex.org/W4712008","https://openalex.org/W98047484","https://openalex.org/W131594596","https://openalex.org/W173811680","https://openalex.org/W236497026","https://openalex.org/W562679892","https://openalex.org/W602685321","https://openalex.org/W1516276319","https://openalex.org/W1539116609","https://openalex.org/W1618841694","https://openalex.org/W1877504628","https://openalex.org/W1975277551","https://openalex.org/W1980658603","https://openalex.org/W1981447246","https://openalex.org/W1987008978","https://openalex.org/W2001954512","https://openalex.org/W2013062623","https://openalex.org/W2014897637","https://openalex.org/W2021962539","https://openalex.org/W2027091032","https://openalex.org/W2028023939","https://openalex.org/W2031740147","https://openalex.org/W2050166167","https://openalex.org/W2050991191","https://openalex.org/W2068664994","https://openalex.org/W2069401294","https://openalex.org/W2076250122","https://openalex.org/W2087203497","https://openalex.org/W2095488178","https://openalex.org/W2097502513","https://openalex.org/W2099510084","https://openalex.org/W2102818386","https://openalex.org/W2103864743","https://openalex.org/W2105471846","https://openalex.org/W2109266693","https://openalex.org/W2117328849","https://openalex.org/W2118166805","https://openalex.org/W2135021243","https://openalex.org/W2145879140","https://openalex.org/W2146774882","https://openalex.org/W2148517650","https://openalex.org/W2160686162","https://openalex.org/W2170077611","https://openalex.org/W2239156852","https://openalex.org/W2332020033","https://openalex.org/W2398819358","https://openalex.org/W2482471426","https://openalex.org/W2975757423","https://openalex.org/W2982472703","https://openalex.org/W2985678631","https://openalex.org/W2998870075","https://openalex.org/W3174969209","https://openalex.org/W3194366811","https://openalex.org/W4249835627","https://openalex.org/W4299695789","https://openalex.org/W4390377592","https://openalex.org/W4409132207"],"related_works":["https://openalex.org/W1605253763","https://openalex.org/W1597940501","https://openalex.org/W3197545142","https://openalex.org/W999262448","https://openalex.org/W7098225669","https://openalex.org/W2021962539","https://openalex.org/W2233371368","https://openalex.org/W4321509897","https://openalex.org/W4406276009","https://openalex.org/W7036212809"],"abstract_inverted_index":{"Antimicrobial":[0],"resistance":[1],"in":[2,16,25,29,76,94,114,127,134],"both":[3],"veterinary":[4],"and":[5,12,40,106,125,131],"human":[6,118],"bacterial":[7],"pathogens":[8],"threaten":[9],"the":[10,50,64],"effectiveness":[11],"access":[13],"to":[14,111],"drugs":[15],"cattle.":[17],"This":[18],"chapter":[19],"addresses":[20],"important":[21],"areas":[22],"of":[23,44],"consideration":[24],"constructing":[26],"antimicrobial":[27],"regimens":[28],"cattle":[30],"within":[31],"this":[32],"context,":[33],"including":[34],"reasonable":[35],"antimicrobials":[36,72,101],"for":[37,54,92],"selected":[38],"diseases":[39],"an":[41],"extended":[42],"discussion":[43],"some":[45],"common":[46],"therapeutic":[47,90],"challenges.":[48],"In":[49],"United":[51],"States,":[52],"regulations":[53],"Extra-label":[55],"Drug":[56,67],"Use":[57,68],"(ELDU)":[58],"were":[59],"promulgated":[60],"as":[61,86,103],"directed":[62],"by":[63],"Animal":[65],"Medicinal":[66],"Clarification":[69],"Act.":[70],"Multiple":[71],"have":[73,108],"been":[74,84,109],"evaluated":[75],"C.":[77],"parvum":[78],"calf":[79],"disease":[80],"models.":[81],"Lasalocid":[82],"has":[83],"used":[85],"a":[87],"preventive":[88],"or":[89,117],"agent":[91],"Cryptosporidium":[93],"calves":[95],"based":[96],"on":[97],"anecdotal":[98],"reports.":[99],"Other":[100],"such":[102],"paromomycin,":[104],"azithromycin,":[105],"clarithromycin":[107],"demonstrated":[110],"be":[112],"efficacious":[113],"murine":[115],"models":[116],"therapy.":[119],"Azithromycin":[120],"significantly":[121],"suppressed":[122],"oocyst":[123],"shedding":[124],"resulted":[126],"significant":[128],"clinical":[129],"improvement":[130],"weight":[132],"gain":[133],"naturally":[135],"infected":[136],"calves.":[137]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2024-11-29T00:00:00"}