{"id":"https://openalex.org/W4404831046","doi":"https://doi.org/10.1038/s41422-024-01055-7","title":"Encoding immune responses: the moonlighting function of alanyl-tRNA synthetase","display_name":"Encoding immune responses: the moonlighting function of alanyl-tRNA synthetase","publication_year":2024,"publication_date":"2024-11-28","ids":{"openalex":"https://openalex.org/W4404831046","doi":"https://doi.org/10.1038/s41422-024-01055-7","pmid":"https://pubmed.ncbi.nlm.nih.gov/39609604","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12012153"},"language":"en","primary_location":{"id":"doi:10.1038/s41422-024-01055-7","doi":"https://doi.org/10.1038/s41422-024-01055-7","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41422-024-01055-7","pdf_url":null,"source":{"id":"https://openalex.org/S128296271","display_name":"Cell Research","issn_l":"1001-0602","issn":["1001-0602","1748-7838"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12012153/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100735654","display_name":"Pin Wang","orcid":"https://orcid.org/0000-0002-2523-2444","observed_orcids":["https://orcid.org/0000-0002-2523-2444"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I4210122727","display_name":"Suzhou Institute of Systems Medicine","ror":"https://ror.org/02szepc22","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210122727","https://openalex.org/I4210141683"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Pin Wang","raw_affiliation_strings":["National Key Laboratory of Immunity and Inflammation, Suzhou Institute of Systems Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Suzhou, Jiangsu, China. wangp@immunol.org","National Key Laboratory of Immunity and Inflammation, Suzhou Institute of Systems Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Suzhou, Jiangsu, China"],"raw_orcid":"https://orcid.org/0000-0002-2523-2444","affiliations":[{"raw_affiliation_string":"National Key Laboratory of Immunity and Inflammation, Suzhou Institute of Systems Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Suzhou, Jiangsu, China. wangp@immunol.org","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I4210122727"]},{"raw_affiliation_string":"National Key Laboratory of Immunity and Inflammation, Suzhou Institute of Systems Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Suzhou, Jiangsu, China","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I4210122727"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065731483","display_name":"Xiaoyu Hu","orcid":"https://orcid.org/0000-0002-4289-6998","observed_orcids":["https://orcid.org/0000-0002-4289-6998"]},"institutions":[{"id":"https://openalex.org/I4210160507","display_name":"Center for Life Sciences","ror":"https://ror.org/05kje8j93","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570","https://openalex.org/I4210160507","https://openalex.org/I99065089"]},{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiaoyu Hu","raw_affiliation_strings":["Institute for Immunology, Tsinghua University, Beijing, China. xiaoyuhu@tsinghua.edu.cn","School of Basic Medical Sciences, Tsinghua University, Beijing, China. xiaoyuhu@tsinghua.edu.cn","Tsinghua-Peking Center for Life Sciences, Beijing, China. xiaoyuhu@tsinghua.edu.cn","Institute for Immunology, Tsinghua University, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0002-4289-6998","affiliations":[{"raw_affiliation_string":"Institute for Immunology, Tsinghua University, Beijing, China. xiaoyuhu@tsinghua.edu.cn","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"School of Basic Medical Sciences, Tsinghua University, Beijing, China. xiaoyuhu@tsinghua.edu.cn","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"Tsinghua-Peking Center for Life Sciences, Beijing, China. xiaoyuhu@tsinghua.edu.cn","institution_ids":["https://openalex.org/I4210160507"]},{"raw_affiliation_string":"Institute for Immunology, Tsinghua University, Beijing, China","institution_ids":["https://openalex.org/I99065089"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5065731483","https://openalex.org/A5100735654"],"corresponding_institution_ids":["https://openalex.org/I200296433","https://openalex.org/I4210122727","https://openalex.org/I4210160507","https://openalex.org/I99065089"],"apc_list":{"value":4990,"currency":"USD","value_usd":4990},"apc_paid":null,"fwci":0.3336,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.44044813,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"35","issue":"5","first_page":"332","last_page":"333"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.42309999465942383,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.42309999465942383,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.2485000044107437,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.08269999921321869,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alanyl-trna-synthetase","display_name":"alanyl-tRNA synthetase","score":0.9959999918937683},{"id":"https://openalex.org/keywords/innate-immune-surveillance","display_name":"innate immune surveillance","score":0.8980000019073486},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.4230000078678131},{"id":"https://openalex.org/keywords/moonlighting-proteins","display_name":"moonlighting proteins","score":0.6460000276565552},{"id":"https://openalex.org/keywords/immune-regulation","display_name":"immune regulation","score":0.46299999952316284}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9404745697975159},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6350526809692383},{"id":"https://openalex.org/C153957851","wikidata":"https://www.wikidata.org/wiki/Q201448","display_name":"Transfer RNA","level":4,"score":0.5958375334739685},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.5780648589134216},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4552861154079437},{"id":"https://openalex.org/C2779315393","wikidata":"https://www.wikidata.org/wiki/Q415968","display_name":"Aminoacyl tRNA synthetase","level":5,"score":0.4176441729068756},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.413576602935791},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.22346708178520203},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.18455860018730164}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1038/s41422-024-01055-7","doi":"https://doi.org/10.1038/s41422-024-01055-7","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41422-024-01055-7","pdf_url":null,"source":{"id":"https://openalex.org/S128296271","display_name":"Cell Research","issn_l":"1001-0602","issn":["1001-0602","1748-7838"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Research","raw_type":"journal-article"},{"id":"pmid:39609604","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39609604","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12012153","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12012153/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Res","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:12012153","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12012153/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Res","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W2063632665","https://openalex.org/W2523989131","https://openalex.org/W2982216374","https://openalex.org/W3133076643","https://openalex.org/W3139135627","https://openalex.org/W4220670155","https://openalex.org/W4390014581","https://openalex.org/W4390487565","https://openalex.org/W4392232595","https://openalex.org/W4392242757","https://openalex.org/W4394998752","https://openalex.org/W4402827312"],"related_works":["https://openalex.org/W4413422862","https://openalex.org/W4402827312","https://openalex.org/W4405039150","https://openalex.org/W4409151479","https://openalex.org/W6950868951","https://openalex.org/W7129008615","https://openalex.org/W2593532650","https://openalex.org/W4408310291","https://openalex.org/W2056579287","https://openalex.org/W4360611251"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2024-11-29T00:00:00"}
