{"id":"https://openalex.org/W4404792128","doi":"https://doi.org/10.33590/microbiolinfectdisam/ezsw5271","title":"Reducing Cardiovascular Risk in HIV: The Unseen Impact of Visceral Fat","display_name":"Reducing Cardiovascular Risk in HIV: The Unseen Impact of Visceral Fat","publication_year":2024,"publication_date":"2024-11-28","ids":{"openalex":"https://openalex.org/W4404792128","doi":"https://doi.org/10.33590/microbiolinfectdisam/ezsw5271"},"language":"en","primary_location":{"id":"doi:10.33590/microbiolinfectdisam/ezsw5271","doi":"https://doi.org/10.33590/microbiolinfectdisam/ezsw5271","is_oa":true,"landing_page_url":"http://dx.doi.org/10.33590/microbiolinfectdisam/ezsw5271","pdf_url":"https://www.emjreviews.com/wp-content/uploads/2024/11/Reducing-Cardiovascular-Risk-in-HIV-The-Unseen-Impact-of-Visceral-Fat-2.pdf","source":{"id":"https://openalex.org/S4404677245","display_name":"Microbiology & infectious diseases :","issn_l":"2977-4055","issn":["2977-4055"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Medical Journal Microbiology and Infectious Diseases","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.emjreviews.com/wp-content/uploads/2024/11/Reducing-Cardiovascular-Risk-in-HIV-The-Unseen-Impact-of-Visceral-Fat-2.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027590697","display_name":"Eleanor Roberts","orcid":"https://orcid.org/0000-0003-2711-1934","observed_orcids":["https://orcid.org/0000-0003-2711-1934"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Eleanor Roberts","raw_affiliation_strings":["Beeline Science Communications, Ltd, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beeline Science Communications, Ltd, UK","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5027590697"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.33569449,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11655","display_name":"HIV-related health complications and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11655","display_name":"HIV-related health complications and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12979","display_name":"Cardiovascular Disease and Adiposity","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv","display_name":"HIV","score":0.8560000061988831},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.8339999914169312},{"id":"https://openalex.org/keywords/visceral-adipose-tissue","display_name":"visceral adipose tissue","score":0.9449999928474426},{"id":"https://openalex.org/keywords/visceral-fat","display_name":"visceral fat","score":0.8119999766349792},{"id":"https://openalex.org/keywords/atherosclerotic-cardiovascular-disease","display_name":"atherosclerotic cardiovascular disease","score":0.8669999837875366},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.7820000052452087},{"id":"https://openalex.org/keywords/growth-hormone","display_name":"growth hormone","score":0.9940000176429749},{"id":"https://openalex.org/keywords/tesamorelin","display_name":"tesamorelin","score":0.9919999837875366},{"id":"https://openalex.org/keywords/antiretroviral-therapy","display_name":"antiretroviral therapy","score":0.968999981880188},{"id":"https://openalex.org/keywords/vamos","display_name":"VAMOS","score":0.6039999723434448},{"id":"https://openalex.org/keywords/lipid-lowering-therapy","display_name":"lipid-lowering therapy","score":0.609000027179718}],"concepts":[{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.658329963684082},{"id":"https://openalex.org/C3020796190","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Visceral fat","level":4,"score":0.599695086479187},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.483859658241272},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.36498045921325684},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.33502358198165894},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.1763613224029541},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.15878114104270935},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.06208398938179016}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.33590/microbiolinfectdisam/ezsw5271","doi":"https://doi.org/10.33590/microbiolinfectdisam/ezsw5271","is_oa":true,"landing_page_url":"http://dx.doi.org/10.33590/microbiolinfectdisam/ezsw5271","pdf_url":"https://www.emjreviews.com/wp-content/uploads/2024/11/Reducing-Cardiovascular-Risk-in-HIV-The-Unseen-Impact-of-Visceral-Fat-2.pdf","source":{"id":"https://openalex.org/S4404677245","display_name":"Microbiology & infectious diseases :","issn_l":"2977-4055","issn":["2977-4055"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Medical Journal Microbiology and Infectious Diseases","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.33590/microbiolinfectdisam/ezsw5271","doi":"https://doi.org/10.33590/microbiolinfectdisam/ezsw5271","is_oa":true,"landing_page_url":"http://dx.doi.org/10.33590/microbiolinfectdisam/ezsw5271","pdf_url":"https://www.emjreviews.com/wp-content/uploads/2024/11/Reducing-Cardiovascular-Risk-in-HIV-The-Unseen-Impact-of-Visceral-Fat-2.pdf","source":{"id":"https://openalex.org/S4404677245","display_name":"Microbiology & infectious diseases :","issn_l":"2977-4055","issn":["2977-4055"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Medical Journal Microbiology and Infectious Diseases","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6700000166893005}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4404792128.pdf","grobid_xml":"https://content.openalex.org/works/W4404792128.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W1965063771","https://openalex.org/W2048331100","https://openalex.org/W2063287755","https://openalex.org/W2066979644","https://openalex.org/W2077744180","https://openalex.org/W2084608105","https://openalex.org/W2091239171","https://openalex.org/W2162249283","https://openalex.org/W2324537014","https://openalex.org/W2514207301","https://openalex.org/W2604509865","https://openalex.org/W2899463601","https://openalex.org/W3025713364","https://openalex.org/W3039108403","https://openalex.org/W3083269300","https://openalex.org/W3176749012","https://openalex.org/W4206612064","https://openalex.org/W4246888238","https://openalex.org/W4250070525","https://openalex.org/W4310567938","https://openalex.org/W4385231305","https://openalex.org/W4387973840","https://openalex.org/W4392004733","https://openalex.org/W4394821966","https://openalex.org/W4398250360","https://openalex.org/W4399653185","https://openalex.org/W4399791515","https://openalex.org/W4400457780","https://openalex.org/W4400961018","https://openalex.org/W4401633862","https://openalex.org/W4402209051"],"related_works":["https://openalex.org/W4387497383","https://openalex.org/W3183948672","https://openalex.org/W3173606202","https://openalex.org/W3110381201","https://openalex.org/W2948807893","https://openalex.org/W2899084033","https://openalex.org/W2778153218","https://openalex.org/W2758277628","https://openalex.org/W2748952813","https://openalex.org/W1531601525"],"abstract_inverted_index":{"While":[0],"modern":[1,62],"antiretroviral":[2],"therapy":[3],"(ART)":[4],"for":[5],"people":[6],"with":[7,31,169],"HIV":[8],"(PWH)":[9],"increases":[10],"life":[11],"expectancy,":[12],"there":[13],"is":[14,35],"still":[15],"an":[16,149],"increased":[17,33],"risk":[18,34,58,106,129,180,215],"of":[19,54,112,183,188,225,237],"developing":[20],"cardiovascular":[21],"disease":[22],"(CVD)":[23],"in":[24,59,101,200,212,220],"this":[25,32],"population.":[26],"As":[27,161],"one":[28],"factor":[29,141],"associated":[30,168],"excess":[36],"visceral":[37,69],"abdominal":[38],"fat":[39],"(EVAF),":[40],"the":[41,52,189],"Visceral":[42],"Adiposity":[43],"Measurement":[44],"and":[45,98,125,131,157,239],"Observations":[46],"Study":[47],"(VAMOS)":[48],"aimed":[49],"to":[50,68,142,165,242],"assess":[51],"impact":[53,244],"EVAF":[55,97,241],"on":[56],"CVD":[57,104,171],"PWH":[60],"taking":[61,229],"ART.":[63],"Participants":[64],"were":[65,227],"grouped":[66],"according":[67],"adipose":[70],"tissue":[71],"(VAT)":[72],"surface":[73,123,159],"area":[74,124],"<130":[75],"cm2":[76,81],"(non-EVAF":[77],"group)":[78],"or":[79],"\u2265130":[80],"(EVAF":[82],"group),":[83],"quantified":[84],"by":[85],"CT":[86],"scan.":[87],"Findings":[88],"presented":[89,204],"at":[90,205],"IDWeek":[91,206],"2024":[92],"revealed":[93],"significant":[94,209],"differences":[95],"between":[96,120,152],"non-EVAF":[99],"groups":[100],"10-year":[102,127,213],"atherosclerotic":[103],"(ASCVD)":[105],"score,":[107],"as":[108,110],"well":[109],"many":[111],"their":[113],"individual":[114],"components.":[115],"VAMOS":[116],"also":[117,203],"showed":[118],"correlations":[119],"increasing":[121,126,173],"VAT":[122,136,158,199],"ASCVD":[128,144,179,214,245],"score":[130,216],"insulin":[132],"resistance":[133],"measures.":[134],"Accordingly,":[135],"may":[137,176],"represent":[138],"a":[139,235],"targetable":[140],"reduce":[143,178,198],"risk.":[145,246],"Also":[146],"shown":[147,219],"was":[148,202,218],"inverse":[150],"relationship":[151],"growth":[153],"hormone":[154,191],"(GH)":[155],"levels":[156,175],"area.":[160],"GH":[162,174],"reductions":[163],"related":[164],"obesity":[166],"are":[167],"elevated":[170],"risk,":[172],"consequently":[177],"score.":[181],"Analysis":[182],"two":[184],"Phase":[185],"III":[186],"trials":[187],"GH-releasing":[190],"(GHRH)":[192],"analogue":[193],"tesamorelin,":[194],"which":[195,226],"can":[196],"significantly":[197],"PWH,":[201],"2024.":[207],"A":[208],"overall":[210],"trend":[211],"reduction":[217],"tesamorelin-treated":[221],"participants,":[222],"around":[223],"half":[224],"already":[228],"lipid":[230],"lowering":[231],"therapies.":[232],"This":[233],"suggests":[234],"benefit":[236],"targeting":[238],"reducing":[240],"further":[243]},"counts_by_year":[],"updated_date":"2026-10-01T08:54:57.152042","created_date":"2025-10-10T00:00:00"}
