{"id":"https://openalex.org/W4404763473","doi":"https://doi.org/10.1016/j.clbc.2024.11.018","title":"Is Progesterone Receptor a Neglected Feature in Breast Cancer? A Retrospective Study Analysing the Clinicopathological Characteristics of Breast Cancer Based on Progesterone Receptor Status","display_name":"Is Progesterone Receptor a Neglected Feature in Breast Cancer? A Retrospective Study Analysing the Clinicopathological Characteristics of Breast Cancer Based on Progesterone Receptor Status","publication_year":2024,"publication_date":"2024-11-27","ids":{"openalex":"https://openalex.org/W4404763473","doi":"https://doi.org/10.1016/j.clbc.2024.11.018","pmid":"https://pubmed.ncbi.nlm.nih.gov/39706710"},"language":"en","primary_location":{"id":"doi:10.1016/j.clbc.2024.11.018","doi":"https://doi.org/10.1016/j.clbc.2024.11.018","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.clbc.2024.11.018","pdf_url":null,"source":{"id":"https://openalex.org/S57202346","display_name":"Clinical Breast Cancer","issn_l":"1526-8209","issn":["1526-8209","1938-0666"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Breast Cancer","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.clbc.2024.11.018","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065936246","display_name":"Ilda Rodrigues","orcid":"https://orcid.org/0000-0002-5581-7670","observed_orcids":["https://orcid.org/0000-0002-5581-7670"]},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]},{"id":"https://openalex.org/I4210158732","display_name":"i3S - Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade, Universidade do Porto","ror":"https://ror.org/04wjk1035","country_code":"PT","type":"facility","lineage":["https://openalex.org/I182534213","https://openalex.org/I4210158732"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Ilda Rodrigues","raw_affiliation_strings":["Biochemistry Unit, Department of Biomedicine, Faculty of Medicine, University of Porto (FMUP), Porto, Portugal; i3S \u2011 Instituto de Inova\u00e7\u00e3o e Investiga\u00e7\u00e3o em Sa\u00fade, University of Porto, Porto, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemistry Unit, Department of Biomedicine, Faculty of Medicine, University of Porto (FMUP), Porto, Portugal; i3S \u2011 Instituto de Inova\u00e7\u00e3o e Investiga\u00e7\u00e3o em Sa\u00fade, University of Porto, Porto, Portugal","institution_ids":["https://openalex.org/I182534213","https://openalex.org/I4210158732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088596124","display_name":"Rute Fernandes","orcid":"https://orcid.org/0000-0002-5534-050X","observed_orcids":["https://orcid.org/0000-0002-5534-050X"]},"institutions":[{"id":"https://openalex.org/I157071867","display_name":"Fernando Pessoa University","ror":"https://ror.org/04h8e7606","country_code":"PT","type":"education","lineage":["https://openalex.org/I157071867"]},{"id":"https://openalex.org/I4210111164","display_name":"IPO Porto","ror":"https://ror.org/027ras364","country_code":"PT","type":"healthcare","lineage":["https://openalex.org/I4210111164"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Rute Fernandes","raw_affiliation_strings":["Faculty of Health Sciences, University Fernando Pessoa, Fernando Pessoa Hospital-School (FCS/HEFP/UFP), Porto, Portugal","Portuguese Oncology Institute of Porto (IPO-Porto), Porto, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences, University Fernando Pessoa, Fernando Pessoa Hospital-School (FCS/HEFP/UFP), Porto, Portugal","institution_ids":["https://openalex.org/I157071867"]},{"raw_affiliation_string":"Portuguese Oncology Institute of Porto (IPO-Porto), Porto, Portugal","institution_ids":["https://openalex.org/I4210111164"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041152282","display_name":"Ana Eliza Francisco Ferreira","orcid":"https://orcid.org/0009-0006-4367-6651","observed_orcids":["https://orcid.org/0009-0006-4367-6651"]},"institutions":[{"id":"https://openalex.org/I4210111164","display_name":"IPO Porto","ror":"https://ror.org/027ras364","country_code":"PT","type":"healthcare","lineage":["https://openalex.org/I4210111164"]},{"id":"https://openalex.org/I4405263123","display_name":"Instituto de Ci\u00eancias Biom\u00e9dicas Albel Salazar","ror":"https://ror.org/02trb6b02","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213","https://openalex.org/I4405263123"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Ana Ferreira","raw_affiliation_strings":["Portuguese Oncology Institute of Porto (IPO-Porto), Porto, Portugal; ICBAS - Abel Salazar Institute of Biomedical Sciences, Porto, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Portuguese Oncology Institute of Porto (IPO-Porto), Porto, Portugal; ICBAS - Abel Salazar Institute of Biomedical Sciences, Porto, Portugal","institution_ids":["https://openalex.org/I4210111164","https://openalex.org/I4405263123"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108120934","display_name":"Deolinda Pereira","orcid":"https://orcid.org/0000-0002-4943-7786","observed_orcids":["https://orcid.org/0000-0002-4943-7786"]},"institutions":[{"id":"https://openalex.org/I4210111164","display_name":"IPO Porto","ror":"https://ror.org/027ras364","country_code":"PT","type":"healthcare","lineage":["https://openalex.org/I4210111164"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Deolinda Pereira","raw_affiliation_strings":["Portuguese Oncology Institute of Porto (IPO-Porto), Porto, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Portuguese Oncology Institute of Porto (IPO-Porto), Porto, Portugal","institution_ids":["https://openalex.org/I4210111164"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018170292","display_name":"R\u00faben Fernandes","orcid":"https://orcid.org/0000-0001-8933-3984","observed_orcids":["https://orcid.org/0000-0001-8933-3984"]},"institutions":[{"id":"https://openalex.org/I157071867","display_name":"Fernando Pessoa University","ror":"https://ror.org/04h8e7606","country_code":"PT","type":"education","lineage":["https://openalex.org/I157071867"]},{"id":"https://openalex.org/I4210111164","display_name":"IPO Porto","ror":"https://ror.org/027ras364","country_code":"PT","type":"healthcare","lineage":["https://openalex.org/I4210111164"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"R\u00faben Fernandes","raw_affiliation_strings":["Faculty of Health Sciences, University Fernando Pessoa, Fernando Pessoa Hospital-School (FCS/HEFP/UFP), Porto, Portugal","Portuguese Oncology Institute of Porto (IPO-Porto), Porto, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences, University Fernando Pessoa, Fernando Pessoa Hospital-School (FCS/HEFP/UFP), Porto, Portugal","institution_ids":["https://openalex.org/I157071867"]},{"raw_affiliation_string":"Portuguese Oncology Institute of Porto (IPO-Porto), Porto, Portugal","institution_ids":["https://openalex.org/I4210111164"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028767906","display_name":"Raquel A. Soares","orcid":"https://orcid.org/0000-0002-9157-5541","observed_orcids":["https://orcid.org/0000-0002-9157-5541"]},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]},{"id":"https://openalex.org/I4210158732","display_name":"i3S - Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade, Universidade do Porto","ror":"https://ror.org/04wjk1035","country_code":"PT","type":"facility","lineage":["https://openalex.org/I182534213","https://openalex.org/I4210158732"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Raquel Soares","raw_affiliation_strings":["Biochemistry Unit, Department of Biomedicine, Faculty of Medicine, University of Porto (FMUP), Porto, Portugal; i3S \u2011 Instituto de Inova\u00e7\u00e3o e Investiga\u00e7\u00e3o em Sa\u00fade, University of Porto, Porto, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemistry Unit, Department of Biomedicine, Faculty of Medicine, University of Porto (FMUP), Porto, Portugal; i3S \u2011 Instituto de Inova\u00e7\u00e3o e Investiga\u00e7\u00e3o em Sa\u00fade, University of Porto, Porto, Portugal","institution_ids":["https://openalex.org/I182534213","https://openalex.org/I4210158732"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033434043","display_name":"Carla Lu\u00eds","orcid":"https://orcid.org/0000-0002-5292-6337","observed_orcids":["https://orcid.org/0000-0002-5292-6337"]},"institutions":[{"id":"https://openalex.org/I157071867","display_name":"Fernando Pessoa University","ror":"https://ror.org/04h8e7606","country_code":"PT","type":"education","lineage":["https://openalex.org/I157071867"]},{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]},{"id":"https://openalex.org/I4210158732","display_name":"i3S - Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade, Universidade do Porto","ror":"https://ror.org/04wjk1035","country_code":"PT","type":"facility","lineage":["https://openalex.org/I182534213","https://openalex.org/I4210158732"]}],"countries":["PT"],"is_corresponding":true,"raw_author_name":"Carla Lu\u00eds","raw_affiliation_strings":["Biochemistry Unit, Department of Biomedicine, Faculty of Medicine, University of Porto (FMUP), Porto, Portugal; i3S \u2011 Instituto de Inova\u00e7\u00e3o e Investiga\u00e7\u00e3o em Sa\u00fade, University of Porto, Porto, Portugal; Faculty of Health Sciences, University Fernando Pessoa, Fernando Pessoa Hospital-School (FCS/HEFP/UFP), Porto, Portugal. Electronic address: carlaluis@med.up.pt"],"raw_orcid":"https://orcid.org/0000-0002-5292-6337","affiliations":[{"raw_affiliation_string":"Biochemistry Unit, Department of Biomedicine, Faculty of Medicine, University of Porto (FMUP), Porto, Portugal; i3S \u2011 Instituto de Inova\u00e7\u00e3o e Investiga\u00e7\u00e3o em Sa\u00fade, University of Porto, Porto, Portugal; Faculty of Health Sciences, University Fernando Pessoa, Fernando Pessoa Hospital-School (FCS/HEFP/UFP), Porto, Portugal. Electronic address: carlaluis@med.up.pt","institution_ids":["https://openalex.org/I157071867","https://openalex.org/I182534213","https://openalex.org/I4210158732"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5033434043"],"corresponding_institution_ids":["https://openalex.org/I157071867","https://openalex.org/I182534213","https://openalex.org/I4210158732"],"apc_list":{"value":3290,"currency":"USD","value_usd":3290},"apc_paid":{"value":3290,"currency":"USD","value_usd":3290},"fwci":1.2235,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.76726592,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"25","issue":"4","first_page":"e331","last_page":"e340"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11134","display_name":"Breast Lesions and Carcinomas","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/progesterone-receptor","display_name":"progesterone receptor","score":0.921999990940094},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.9919999837875366},{"id":"https://openalex.org/keywords/clinicopathological-features","display_name":"clinicopathological features","score":0.8349999785423279},{"id":"https://openalex.org/keywords/progesterone-receptor-negativity","display_name":"progesterone receptor negativity","score":0.7850000262260437},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.7960000038146973},{"id":"https://openalex.org/keywords/histological-subtypes","display_name":"histological subtypes","score":0.8399999737739563},{"id":"https://openalex.org/keywords/tumor-grade","display_name":"tumor grade","score":0.8709999918937683},{"id":"https://openalex.org/keywords/tumor-stage","display_name":"tumor stage","score":0.9929999709129333},{"id":"https://openalex.org/keywords/estrogen-receptor","display_name":"estrogen receptor","score":0.9570000171661377},{"id":"https://openalex.org/keywords/her2","display_name":"HER2","score":0.9319999814033508},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9330000281333923},{"id":"https://openalex.org/keywords/hormone-receptor-status","display_name":"hormone receptor status","score":0.5270000100135803}],"concepts":[{"id":"https://openalex.org/C98717036","wikidata":"https://www.wikidata.org/wiki/Q14872994","display_name":"Progesterone receptor","level":5,"score":0.8463336229324341},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8461354970932007},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.8325912952423096},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.6073150038719177},{"id":"https://openalex.org/C2910080358","wikidata":"https://www.wikidata.org/wiki/Q416496","display_name":"Oestrogen receptor","level":4,"score":0.5132389068603516},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5105727910995483},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4730193614959717},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4499906897544861},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.41727519035339355},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.328134685754776},{"id":"https://openalex.org/C84606932","wikidata":"https://www.wikidata.org/wiki/Q416496","display_name":"Estrogen receptor","level":4,"score":0.24448862671852112}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009367","descriptor_name":"Neoplasm Staging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011174","descriptor_name":"Portugal","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011960","descriptor_name":"Receptors, Estrogen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011980","descriptor_name":"Receptors, Progesterone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015992","descriptor_name":"Body Mass Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018719","descriptor_name":"Erb-b2 Receptor Tyrosine Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.clbc.2024.11.018","doi":"https://doi.org/10.1016/j.clbc.2024.11.018","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.clbc.2024.11.018","pdf_url":null,"source":{"id":"https://openalex.org/S57202346","display_name":"Clinical Breast Cancer","issn_l":"1526-8209","issn":["1526-8209","1938-0666"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Breast Cancer","raw_type":"journal-article"},{"id":"pmid:39706710","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39706710","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical breast cancer","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.clbc.2024.11.018","doi":"https://doi.org/10.1016/j.clbc.2024.11.018","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.clbc.2024.11.018","pdf_url":null,"source":{"id":"https://openalex.org/S57202346","display_name":"Clinical Breast Cancer","issn_l":"1526-8209","issn":["1526-8209","1938-0666"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Breast Cancer","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G8525522055","display_name":null,"funder_award_id":"LPCC-NRN 2024","funder_id":"https://openalex.org/F4320327240","funder_display_name":"Liga Portuguesa Contra o Cancro"}],"funders":[{"id":"https://openalex.org/F4320327240","display_name":"Liga Portuguesa Contra o Cancro","ror":"https://ror.org/03r31ar10"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W652367848","https://openalex.org/W1531333714","https://openalex.org/W1881540319","https://openalex.org/W1967997862","https://openalex.org/W1970346106","https://openalex.org/W1975347641","https://openalex.org/W1994480513","https://openalex.org/W2008021904","https://openalex.org/W2036638605","https://openalex.org/W2042941276","https://openalex.org/W2043616061","https://openalex.org/W2048939997","https://openalex.org/W2051230533","https://openalex.org/W2068104926","https://openalex.org/W2081462460","https://openalex.org/W2082559087","https://openalex.org/W2096429037","https://openalex.org/W2117775530","https://openalex.org/W2143006474","https://openalex.org/W2344614355","https://openalex.org/W2555438740","https://openalex.org/W2771349858","https://openalex.org/W2782929519","https://openalex.org/W2789230893","https://openalex.org/W2803973904","https://openalex.org/W2903613251","https://openalex.org/W2938054231","https://openalex.org/W2938860266","https://openalex.org/W2973077025","https://openalex.org/W2977149423","https://openalex.org/W2980534320","https://openalex.org/W3018740144","https://openalex.org/W3031808580","https://openalex.org/W3033166085","https://openalex.org/W3080908295","https://openalex.org/W3081515091","https://openalex.org/W3087240514","https://openalex.org/W3128646645","https://openalex.org/W3161303985","https://openalex.org/W4205724345","https://openalex.org/W4206995975","https://openalex.org/W4212865994","https://openalex.org/W4313236873"],"related_works":["https://openalex.org/W2689215136","https://openalex.org/W4414700107","https://openalex.org/W2755651487","https://openalex.org/W164988692","https://openalex.org/W2397711413","https://openalex.org/W1986171148","https://openalex.org/W7127652698","https://openalex.org/W3161277385","https://openalex.org/W7220301342","https://openalex.org/W4206988787"],"abstract_inverted_index":{"PURPOSE:":[0],"The":[1,93,178],"aim":[2],"of":[3,151,224],"this":[4],"study":[5,94],"is":[6,200,217],"to":[7,51,148,219,226,231],"analyse":[8],"PR":[9,185],"independently":[10],"and":[11,16,24,61,71,79,113,136,161,164,186,195,210,230],"its":[12,75,80],"relationship":[13],"with":[14,101,202],"demographic":[15],"clinicopathological":[17],"information.":[18],"INTRODUCTION:":[19],"Steroid":[20],"hormones,":[21],"particularly":[22],"estrogen":[23,41,60,133],"progesterone,":[25,62],"play":[26],"a":[27,181],"crucial":[28,64],"role":[29],"in":[30,65,108],"breast":[31,47,227],"cancer":[32,48,228],"(BC)":[33],"etiology.":[34],"Research":[35],"attention":[36],"has":[37,49],"focused":[38],"mainly":[39],"on":[40,46],"while":[42],"the":[43,104,149,221],"progesterone":[44,78,225],"impact":[45],"yet":[50],"be":[52],"fully":[53],"uncover.":[54],"Hormone":[55],"receptors,":[56],"including":[57,116,206],"those":[58],"for":[59,173,235],"are":[63],"BC":[66,102],"molecular":[67],"classification,":[68],"shaping":[69],"prognosis":[70],"treatment":[72],"strategies.":[73],"Beyond":[74],"metabolic":[76],"effects,":[77],"receptor":[81,134,198],"(PR)":[82],"have":[83],"significant":[84],"clinical":[85,88,204],"implications,":[86],"impacting":[87],"outcomes.":[89,238],"MATERIALS":[90],"AND":[91],"METHODS:":[92],"comprised":[95],"2223":[96],"women":[97],"who":[98],"were":[99,145],"diagnosed":[100],"at":[103,118],"Comprehensive":[105],"Cancer":[106],"Centre":[107],"Portugal":[109],"(IPO-Porto)":[110],"between":[111,184],"2012":[112],"2016.":[114],"Variables,":[115],"age":[117],"diagnosis,":[119],"body":[120],"mass":[121],"index":[122],"(BMI),":[123],"laterality,":[124],"topographic":[125],"localization,":[126],"histological":[127,188],"type,":[128,189],"differentiation":[129,190],"grade,":[130,191],"tumor":[131,208],"stage,":[132,193],"(ER)":[135],"Human":[137],"Epidermal":[138],"growth":[139],"factor":[140],"Receptor":[141],"2":[142],"(HER2)":[143],"expression,":[144],"stratified":[146],"according":[147],"expression":[150],"Progesterone":[152,197],"Receptor.":[153],"Statistical":[154,169],"analysis":[155],"included":[156],"Pearson's":[157],"Chi-squared":[158],"test,":[159],"binary":[160],"multinomial":[162],"regression,":[163],"Cox":[165],"proportional":[166],"hazard":[167],"model.":[168],"significance":[170],"was":[171],"set":[172],"P":[174],"<":[175],".05.":[176],"RESULTS:":[177],"results":[179],"reveal":[180],"statistical":[182],"association":[183],"BMI,":[187],"tumour":[192],"ER":[194],"HER2.":[196],"negativity":[199],"associated":[201],"adverse":[203],"outcomes,":[205],"advanced":[207],"stages,":[209],"diminished":[211],"overall":[212],"survival.":[213],"CONCLUSION:":[214],"Further":[215],"research":[216],"needed":[218],"elucidate":[220],"precise":[222],"contributions":[223],"progression":[229],"optimize":[232],"therapeutic":[233],"approaches":[234],"improved":[236],"patient":[237]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":5}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2024-11-28T00:00:00"}