{"id":"https://openalex.org/W4404691663","doi":"https://doi.org/10.1094/mpmi-10-24-0127-ta","title":"Generation of Inheritable A-to-G Transitions Using Adenine Base Editing and NG-PAM Cas9 in Arabidopsis thaliana","display_name":"Generation of Inheritable A-to-G Transitions Using Adenine Base Editing and NG-PAM Cas9 in Arabidopsis thaliana","publication_year":2024,"publication_date":"2024-11-25","ids":{"openalex":"https://openalex.org/W4404691663","doi":"https://doi.org/10.1094/mpmi-10-24-0127-ta","pmid":"https://pubmed.ncbi.nlm.nih.gov/39585742"},"language":"en","primary_location":{"id":"doi:10.1094/mpmi-10-24-0127-ta","doi":"https://doi.org/10.1094/mpmi-10-24-0127-ta","is_oa":true,"landing_page_url":"https://doi.org/10.1094/mpmi-10-24-0127-ta","pdf_url":null,"source":{"id":"https://openalex.org/S88768767","display_name":"Molecular Plant-Microbe Interactions","issn_l":"0894-0282","issn":["0894-0282","1943-7706"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320276","host_organization_name":"American Phytopathological Society","host_organization_lineage":["https://openalex.org/P4310320276"],"host_organization_lineage_names":["American Phytopathological Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Plant-Microbe Interactions\u00ae","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W4404691663"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1094/mpmi-10-24-0127-ta","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063460903","display_name":"Yi Yun Tan","orcid":"https://orcid.org/0000-0002-6773-9809","observed_orcids":["https://orcid.org/0000-0002-6773-9809"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Yi Yun Tan","raw_affiliation_strings":["Department of Biological Sciences, National University of Singapore, 117558, Singapore","National University of Singapore , Biological Sciences, Singapore, --, Singapore;"],"raw_orcid":"https://orcid.org/0000-0002-6773-9809","affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, National University of Singapore, 117558, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"National University of Singapore , Biological Sciences, Singapore, --, Singapore;","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006670183","display_name":"Yin Yin Liew","orcid":"https://orcid.org/0000-0002-3816-3599","observed_orcids":["https://orcid.org/0000-0002-3816-3599"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Yin Yin Liew","raw_affiliation_strings":["Department of Biological Sciences, National University of Singapore, 117558, Singapore","National University of Singapore , Biological Sciences, Singapore, --, Singapore;"],"raw_orcid":"https://orcid.org/0000-0002-3816-3599","affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, National University of Singapore, 117558, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"National University of Singapore , Biological Sciences, Singapore, --, Singapore;","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041049728","display_name":"Rachelle R.Q. Lee","orcid":"https://orcid.org/0000-0003-3267-2699","observed_orcids":["https://orcid.org/0000-0003-3267-2699"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Rachelle R. Q. Lee","raw_affiliation_strings":["Department of Biological Sciences, National University of Singapore, 117558, Singapore","National University of Singapore , Biological Sciences, Singapore, --, Singapore;"],"raw_orcid":"https://orcid.org/0000-0003-3267-2699","affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, National University of Singapore, 117558, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"National University of Singapore , Biological Sciences, Singapore, --, Singapore;","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034927034","display_name":"Baptiste Castel","orcid":"https://orcid.org/0000-0002-2722-0228","observed_orcids":["https://orcid.org/0000-0002-2722-0228"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Baptiste Castel","raw_affiliation_strings":["Department of Biological Sciences, National University of Singapore, 117558, Singapore","National University of Singapore , Biological Sciences, Singapore, --, Singapore;"],"raw_orcid":"https://orcid.org/0000-0002-2722-0228","affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, National University of Singapore, 117558, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"National University of Singapore , Biological Sciences, Singapore, --, Singapore;","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Nga Man Chan","orcid":"https://orcid.org/0009-0006-7430-7680","observed_orcids":["https://orcid.org/0009-0006-7430-7680"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Nga Man Chan","raw_affiliation_strings":["Department of Biological Sciences, National University of Singapore, 117558, Singapore","National University of Singapore , Biological Sciences, Singapore, --, Singapore;"],"raw_orcid":"https://orcid.org/0009-0006-7430-7680","affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, National University of Singapore, 117558, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"National University of Singapore , Biological Sciences, Singapore, --, Singapore;","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Wei-Lin Wan","orcid":"https://orcid.org/0000-0002-2062-8466","observed_orcids":["https://orcid.org/0000-0002-2062-8466"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Wei-Lin Wan","raw_affiliation_strings":["Department of Biological Sciences, National University of Singapore, 117558, Singapore","National University of Singapore , Biological Sciences, Singapore, --, Singapore;"],"raw_orcid":"https://orcid.org/0000-0002-2062-8466","affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, National University of Singapore, 117558, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"National University of Singapore , Biological Sciences, Singapore, --, Singapore;","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101743499","display_name":"Yizhong Zhang","orcid":"https://orcid.org/0000-0003-3035-3037","observed_orcids":["https://orcid.org/0000-0003-3035-3037"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Yizhong Zhang","raw_affiliation_strings":["Department of Biological Sciences, National University of Singapore, 117558, Singapore","National University of Singapore , Biological Sciences, Singapore, --, Singapore;"],"raw_orcid":"https://orcid.org/0000-0003-3035-3037","affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, National University of Singapore, 117558, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"National University of Singapore , Biological Sciences, Singapore, --, Singapore;","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102511808","display_name":"Donghui Hu","orcid":"https://orcid.org/0000-0002-3432-3292","observed_orcids":["https://orcid.org/0000-0002-3432-3292"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Donghui Hu","raw_affiliation_strings":["Department of Biological Sciences, National University of Singapore, 117558, Singapore","National University of Singapore , Biological Sciences, Singapore, --, Singapore;"],"raw_orcid":"https://orcid.org/0000-0002-3432-3292","affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, National University of Singapore, 117558, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"National University of Singapore , Biological Sciences, Singapore, --, Singapore;","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Persis Chan","orcid":"https://orcid.org/0009-0009-5523-4852","observed_orcids":["https://orcid.org/0009-0009-5523-4852"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Persis Chan","raw_affiliation_strings":["Department of Biological Sciences, National University of Singapore, 117558, Singapore","National University of Singapore , Biological Sciences, Singapore, --, Singapore;"],"raw_orcid":"https://orcid.org/0009-0009-5523-4852","affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, National University of Singapore, 117558, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"National University of Singapore , Biological Sciences, Singapore, --, Singapore;","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058382490","display_name":"Sang\u2010Tae Kim","orcid":"https://orcid.org/0000-0003-1645-6021","observed_orcids":["https://orcid.org/0000-0003-1645-6021","https://orcid.org/0000-0003-4847-1306"]},"institutions":[{"id":"https://openalex.org/I87111246","display_name":"Catholic University of Korea","ror":"https://ror.org/01fpnj063","country_code":"KR","type":"education","lineage":["https://openalex.org/I87111246"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sang-Tae Kim","raw_affiliation_strings":["Department of Medical & Biological Sciences, The Catholic University of Korea, Bucheon 14662, Republic of Korea","The Catholic University of Korea, Dept. of Medical & Biological Sciences, Bucheon, Korea (the Republic of);"],"raw_orcid":"https://orcid.org/0000-0003-1645-6021","affiliations":[{"raw_affiliation_string":"Department of Medical & Biological Sciences, The Catholic University of Korea, Bucheon 14662, Republic of Korea","institution_ids":["https://openalex.org/I87111246"]},{"raw_affiliation_string":"The Catholic University of Korea, Dept. of Medical & Biological Sciences, Bucheon, Korea (the Republic of);","institution_ids":["https://openalex.org/I87111246"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043428880","display_name":"Eunyoung Chae","orcid":"https://orcid.org/0000-0002-0889-9837","observed_orcids":["https://orcid.org/0000-0002-0889-9837"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB","SG"],"is_corresponding":false,"raw_author_name":"Eunyoung Chae","raw_affiliation_strings":["Department of Biological Sciences, National University of Singapore, 117558, Singapore","Department of Biology, University of Oxford, Oxford OX1 3RB, United Kingdom","National University of Singapore , Biological Sciences, 16 Science Drive 4, National Univ. Singapore, Singapore, --, Singapore, 117558;"],"raw_orcid":"https://orcid.org/0000-0002-0889-9837","affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, National University of Singapore, 117558, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Department of Biology, University of Oxford, Oxford OX1 3RB, United Kingdom","institution_ids":["https://openalex.org/I40120149"]},{"raw_affiliation_string":"National University of Singapore , Biological Sciences, 16 Science Drive 4, National Univ. Singapore, Singapore, --, Singapore, 117558;","institution_ids":["https://openalex.org/I165932596"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":{"value":3000,"currency":"USD","value_usd":3000},"fwci":0.1084,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.29080011,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"38","issue":"1","first_page":"30","last_page":"42"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10878","display_name":"CRISPR and Genetic Engineering","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10878","display_name":"CRISPR and Genetic Engineering","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12610","display_name":"RNA regulation and disease","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12828","display_name":"Plant Genetic and Mutation Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adenine-base-editing","display_name":"adenine base editing","score":0.9739999771118164},{"id":"https://openalex.org/keywords/pam-recognition","display_name":"PAM recognition","score":0.6039999723434448},{"id":"https://openalex.org/keywords/arabidopsis-thaliana","display_name":"Arabidopsis thaliana","score":0.8080000281333923},{"id":"https://openalex.org/keywords/nlr-proteins","display_name":"NLR proteins","score":0.8790000081062317},{"id":"https://openalex.org/keywords/p-loop-motif","display_name":"P-loop motif","score":0.7260000109672546},{"id":"https://openalex.org/keywords/autoimmune-phenotype","display_name":"autoimmune phenotype","score":0.550000011920929},{"id":"https://openalex.org/keywords/genome-editing","display_name":"genome editing","score":0.5339999794960022}],"concepts":[{"id":"https://openalex.org/C2775988993","wikidata":"https://www.wikidata.org/wiki/Q158695","display_name":"Arabidopsis thaliana","level":4,"score":0.8195720314979553},{"id":"https://openalex.org/C98108389","wikidata":"https://www.wikidata.org/wiki/Q412563","display_name":"CRISPR","level":3,"score":0.6562117338180542},{"id":"https://openalex.org/C144501496","wikidata":"https://www.wikidata.org/wiki/Q5533489","display_name":"Genome editing","level":4,"score":0.577138364315033},{"id":"https://openalex.org/C42058472","wikidata":"https://www.wikidata.org/wiki/Q810214","display_name":"Base (topology)","level":2,"score":0.5641936659812927},{"id":"https://openalex.org/C132455925","wikidata":"https://www.wikidata.org/wiki/Q16965677","display_name":"Cas9","level":4,"score":0.5296043157577515},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.49952244758605957},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4904906451702118},{"id":"https://openalex.org/C2779491563","wikidata":"https://www.wikidata.org/wiki/Q157892","display_name":"Arabidopsis","level":4,"score":0.49033117294311523},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3772444725036621},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2102436125278473},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.18789386749267578},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000072669","descriptor_name":"Gene Editing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D000076987","descriptor_name":"CRISPR-Associated Protein 9","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000076987","descriptor_name":"CRISPR-Associated Protein 9","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000225","descriptor_name":"Adenine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000243","descriptor_name":"Adenosine Deaminase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000243","descriptor_name":"Adenosine Deaminase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D029681","descriptor_name":"Arabidopsis Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029681","descriptor_name":"Arabidopsis Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D030821","descriptor_name":"Plants, Genetically Modified","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064113","descriptor_name":"CRISPR-Cas Systems","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1094/mpmi-10-24-0127-ta","doi":"https://doi.org/10.1094/mpmi-10-24-0127-ta","is_oa":true,"landing_page_url":"https://doi.org/10.1094/mpmi-10-24-0127-ta","pdf_url":null,"source":{"id":"https://openalex.org/S88768767","display_name":"Molecular Plant-Microbe Interactions","issn_l":"0894-0282","issn":["0894-0282","1943-7706"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320276","host_organization_name":"American Phytopathological Society","host_organization_lineage":["https://openalex.org/P4310320276"],"host_organization_lineage_names":["American Phytopathological Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Plant-Microbe Interactions\u00ae","raw_type":"journal-article"},{"id":"doi:10.1101/2022.06.07.495175","doi":"https://doi.org/10.1101/2022.06.07.495175","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2022.06.07.495175","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2022/06/07/2022.06.07.495175.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmid:39585742","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39585742","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular plant-microbe interactions : MPMI","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-05783637v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-05783637","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Molecular Plant-Microbe Interactions, 2025, 38 (1), pp.30-42. &#x27E8;10.1094/MPMI-10-24-0127-TA&#x27E9;","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:c9b08c6e058f45e9958a8166b68efa79","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/c9b08c6e058f45e9958a8166b68efa79","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Molecular Plant-Microbe Interactions, Vol 38, Iss 1, Pp 30-42 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1094/mpmi-10-24-0127-ta","doi":"https://doi.org/10.1094/mpmi-10-24-0127-ta","is_oa":true,"landing_page_url":"https://doi.org/10.1094/mpmi-10-24-0127-ta","pdf_url":null,"source":{"id":"https://openalex.org/S88768767","display_name":"Molecular Plant-Microbe Interactions","issn_l":"0894-0282","issn":["0894-0282","1943-7706"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320276","host_organization_name":"American Phytopathological Society","host_organization_lineage":["https://openalex.org/P4310320276"],"host_organization_lineage_names":["American Phytopathological Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Plant-Microbe Interactions\u00ae","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1052091335","display_name":null,"funder_award_id":"MOE-T2EP30221-0012","funder_id":"https://openalex.org/F4320320751","funder_display_name":"Ministry of Education - Singapore"},{"id":"https://openalex.org/G1698720261","display_name":null,"funder_award_id":"SFS RND SUFP 002 04","funder_id":"https://openalex.org/F1200118845","funder_display_name":"Singapore Food Agency"},{"id":"https://openalex.org/G3968125494","display_name":null,"funder_award_id":"2022R1A2C1011598","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G4381756097","display_name":null,"funder_award_id":"NRF-CRP22-2019-0001","funder_id":"https://openalex.org/F4320320671","funder_display_name":"National Research Foundation"},{"id":"https://openalex.org/G4789271885","display_name":null,"funder_award_id":"NRF\u2010CRP22\u20102019\u20100001","funder_id":"https://openalex.org/F4320320709","funder_display_name":"National Research Foundation Singapore"},{"id":"https://openalex.org/G6084112770","display_name":null,"funder_award_id":"NRF-CRP22-2019-000","funder_id":"https://openalex.org/F4320320709","funder_display_name":"National Research Foundation Singapore"}],"funders":[{"id":"https://openalex.org/F1200118845","display_name":"Singapore Food Agency","ror":"https://ror.org/0478mpy30"},{"id":"https://openalex.org/F4320320671","display_name":"National Research Foundation","ror":"https://ror.org/05s0g1g46"},{"id":"https://openalex.org/F4320320709","display_name":"National Research Foundation Singapore","ror":"https://ror.org/03cpyc314"},{"id":"https://openalex.org/F4320320751","display_name":"Ministry of Education - Singapore","ror":"https://ror.org/01kcva023"},{"id":"https://openalex.org/F4320322120","display_name":"National Research Foundation of Korea","ror":"https://ror.org/013aysd81"},{"id":"https://openalex.org/F4320328359","display_name":"Ministry of Science and ICT, South Korea","ror":"https://ror.org/01wpjm123"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4404691663.pdf","grobid_xml":"https://content.openalex.org/works/W4404691663.grobid-xml"},"referenced_works_count":82,"referenced_works":["https://openalex.org/W124504601","https://openalex.org/W2000071580","https://openalex.org/W2021341670","https://openalex.org/W2021767455","https://openalex.org/W2045435533","https://openalex.org/W2057055150","https://openalex.org/W2087157154","https://openalex.org/W2094100452","https://openalex.org/W2115603949","https://openalex.org/W2116122104","https://openalex.org/W2123355136","https://openalex.org/W2124439705","https://openalex.org/W2140767747","https://openalex.org/W2149751339","https://openalex.org/W2155758567","https://openalex.org/W2167340357","https://openalex.org/W2289229574","https://openalex.org/W2336828812","https://openalex.org/W2419574648","https://openalex.org/W2529822210","https://openalex.org/W2560407750","https://openalex.org/W2607473129","https://openalex.org/W2740956148","https://openalex.org/W2766599608","https://openalex.org/W2806398251","https://openalex.org/W2809042973","https://openalex.org/W2883250809","https://openalex.org/W2889513238","https://openalex.org/W2892968638","https://openalex.org/W2898448050","https://openalex.org/W2902051551","https://openalex.org/W2915437394","https://openalex.org/W2915459742","https://openalex.org/W2916364858","https://openalex.org/W2917855738","https://openalex.org/W2923786627","https://openalex.org/W2923815554","https://openalex.org/W2924139971","https://openalex.org/W2924822346","https://openalex.org/W2936252965","https://openalex.org/W2939811618","https://openalex.org/W2952594972","https://openalex.org/W2969702518","https://openalex.org/W2969924257","https://openalex.org/W2987098669","https://openalex.org/W3012327875","https://openalex.org/W3013504322","https://openalex.org/W3034029360","https://openalex.org/W3037843245","https://openalex.org/W3045144021","https://openalex.org/W3106552706","https://openalex.org/W3108046194","https://openalex.org/W3117329982","https://openalex.org/W3117645379","https://openalex.org/W3119743458","https://openalex.org/W3121977414","https://openalex.org/W3125911148","https://openalex.org/W3129449856","https://openalex.org/W3134800304","https://openalex.org/W3153471580","https://openalex.org/W3153670863","https://openalex.org/W3162076385","https://openalex.org/W3163110995","https://openalex.org/W3164518980","https://openalex.org/W3194399644","https://openalex.org/W3197925163","https://openalex.org/W3199993477","https://openalex.org/W3202019887","https://openalex.org/W3210099333","https://openalex.org/W4200168383","https://openalex.org/W4200603676","https://openalex.org/W4205661453","https://openalex.org/W4210558208","https://openalex.org/W4212982604","https://openalex.org/W4221016141","https://openalex.org/W4245053291","https://openalex.org/W4293458015","https://openalex.org/W4376609350","https://openalex.org/W4376609794","https://openalex.org/W4376610549","https://openalex.org/W4391151849","https://openalex.org/W4392163843"],"related_works":["https://openalex.org/W2806478486","https://openalex.org/W2936252965","https://openalex.org/W4286210002","https://openalex.org/W2766599608","https://openalex.org/W3129449856","https://openalex.org/W4382057164","https://openalex.org/W2915177587","https://openalex.org/W3210099333","https://openalex.org/W2964746954","https://openalex.org/W2949111738"],"abstract_inverted_index":{"Towards":[0],"precise":[1],"genome":[2],"editing,":[3],"base":[4,20,25,104],"editors":[5],"have":[6],"been":[7],"developed":[8,29],"by":[9],"fusing":[10],"catalytically":[11],"compromised":[12],"Cas9":[13],"with":[14,42,77,89,146,230],"deaminase":[15],"components,":[16],"mediating":[17],"C-to-T":[18],"(cytosine":[19],"editors)":[21,26],"or":[22,46],"A-to-G":[23,67,164],"(adenine":[24],"transition.":[27],"We":[28,128,160],"a":[30,36,49,73,112,143,226,234],"set":[31],"of":[32,35,40,116,157,163,220,252],"vectors":[33],"consisting":[34],"5\u2032-NG-3\u2032":[37],"PAM-recognizing":[38],"variant":[39],"SpCas9":[41],"adenosine":[43],"deaminases":[44],"TadA7.10":[45],"TadA8e.":[47],"Using":[48],"phenotype-based":[50],"screen":[51],"in":[52,69,121,165,184,191,198,218,225],"Arabidopsis":[53],"thaliana":[54],"targeting":[55,149,189],"multiple":[56],"PDS3":[57],"intron":[58],"splice":[59,74],"sites,":[60],"we":[61,110],"achieved":[62,83,217],"up":[63],"to":[64,241,248],"81%":[65],"somatic":[66],"editing":[68,215],"primary":[70],"transformants":[71],"at":[72],"acceptor":[75],"site":[76],"NGG":[78],"PAM,":[79],"while":[80],"35%":[81],"was":[82,209,216],"for":[84,125,169,255],"the":[85,101,150,180,193,221,231,250,273],"same":[86],"target":[87],"adenine":[88,103,173],"NGA":[90,147],"PAM.":[91,127],"Among":[92],"tested":[93],"vectors,":[94],"pECNUS4":[95],"(Addgene":[96],"#184887),":[97],"carrying":[98],"TadA8e,":[99],"showed":[100],"highest":[102],"editor":[105],"(ABE)":[106],"efficiency.":[107],"With":[108],"pECNUS4,":[109],"recreated":[111],"naturally":[113],"occurring":[114],"allele":[115],"DANGEROUS":[117],"MIX3":[118],"(":[119],"DM3)":[120],"two":[122,199],"generations,":[123],"transgene-free,":[124],"NGC":[126],"also":[129],"simultaneously":[130,208],"base-edited":[131],"four":[132],"redundant":[133],"DM1/SSI4":[134],"homologs,":[135],"encoding":[136],"nucleotide-binding":[137],"leucine-rich":[138],"repeat":[139],"(NLR)":[140],"proteins,":[141],"using":[142],"single":[144],"gRNA":[145],"PAM":[148],"conserved":[151],"yet":[152],"functionally":[153],"crucial":[154],"P-loop":[155],"motif":[156],"NLR":[158,167,206],"proteins.":[159,256],"found":[161],"fixation":[162],"three":[166,171],"genes":[168,182,207],"all":[170],"possible":[172,223],"sites":[174],"within":[175],"base-editing":[176],"window":[177],"3-9,":[178],"as":[179,211],"edited":[181],"segregate":[183],"T":[185,227],"2":[186],".":[187,279],"Multigene":[188],"succeeded":[190],"rescuing":[192],"previously":[194],"reported":[195],"autoimmune":[196],"phenotype":[197],"generations.":[200],"Mediating":[201],"desired":[202],"ABE":[203,239],"on":[204],"seven":[205,222],"successful":[210],"well;":[212],"above":[213],"77%":[214],"six":[219],"targets":[224],"1":[228],"plant,":[229],"remaining":[232],"having":[233],"moderately":[235],"high":[236],"(32%)":[237],"editing.":[238],"application":[240],"specifically":[242],"inactivate":[243],"functional":[244],"motifs":[245],"is":[246,266],"anticipated":[247],"expedite":[249],"discovery":[251],"novel":[253],"roles":[254],"[Formula:":[257],"see":[258],"text]":[259],"Copyright":[260],"\u00a9":[261],"2025":[262],"The":[263],"Author(s).":[264],"This":[265],"an":[267],"open":[268],"access":[269],"article":[270],"distributed":[271],"under":[272],"CC":[274],"BY":[275],"4.0":[276],"International":[277],"license":[278]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2024-11-26T00:00:00"}
