{"id":"https://openalex.org/W4404563282","doi":"https://doi.org/10.1016/j.phyplu.2024.100691","title":"The effect of the fenugreek hydrolyzed protein on lipid profile in patients with mild-to-moderate hypercholesterolemia: A confirmatory triple-blind randomized-controlled clinical trial","display_name":"The effect of the fenugreek hydrolyzed protein on lipid profile in patients with mild-to-moderate hypercholesterolemia: A confirmatory triple-blind randomized-controlled clinical trial","publication_year":2024,"publication_date":"2024-11-20","ids":{"openalex":"https://openalex.org/W4404563282","doi":"https://doi.org/10.1016/j.phyplu.2024.100691","pmid":"https://pubmed.ncbi.nlm.nih.gov/39935620","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11808590"},"language":"en","primary_location":{"id":"doi:10.1016/j.phyplu.2024.100691","doi":"https://doi.org/10.1016/j.phyplu.2024.100691","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.phyplu.2024.100691","pdf_url":null,"source":{"id":"https://openalex.org/S4210212705","display_name":"Phytomedicine Plus","issn_l":"2667-0313","issn":["2667-0313"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phytomedicine Plus","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.phyplu.2024.100691","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5143973334","display_name":"Mahdi Badiee-Gavarti","orcid":"https://orcid.org/0000-0001-7353-9507","observed_orcids":["https://orcid.org/0000-0001-7353-9507"]},"institutions":[{"id":"https://openalex.org/I114982161","display_name":"Isfahan University of Medical Sciences","ror":"https://ror.org/04waqzz56","country_code":"IR","type":"education","lineage":["https://openalex.org/I114982161"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mahdi Badiee Gavarti","raw_affiliation_strings":["Student Research Committee, School of Medicine, Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran"],"raw_orcid":"https://orcid.org/0000-0001-7353-9507","affiliations":[{"raw_affiliation_string":"Student Research Committee, School of Medicine, Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran","institution_ids":["https://openalex.org/I114982161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036469613","display_name":"Ali Askari","orcid":"https://orcid.org/0000-0003-2835-0283","observed_orcids":["https://orcid.org/0000-0003-2835-0283"]},"institutions":[{"id":"https://openalex.org/I114982161","display_name":"Isfahan University of Medical Sciences","ror":"https://ror.org/04waqzz56","country_code":"IR","type":"education","lineage":["https://openalex.org/I114982161"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Ali Askari","raw_affiliation_strings":["Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran"],"raw_orcid":"https://orcid.org/0000-0003-2835-0283","affiliations":[{"raw_affiliation_string":"Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran","institution_ids":["https://openalex.org/I114982161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044946754","display_name":"Hamidreza Roohafza","orcid":"https://orcid.org/0000-0003-3582-0431","observed_orcids":["https://orcid.org/0000-0003-3582-0431"]},"institutions":[{"id":"https://openalex.org/I114982161","display_name":"Isfahan University of Medical Sciences","ror":"https://ror.org/04waqzz56","country_code":"IR","type":"education","lineage":["https://openalex.org/I114982161"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Hamidreza Roohafza","raw_affiliation_strings":["Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran","institution_ids":["https://openalex.org/I114982161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081058067","display_name":"Mozhde Askari","orcid":"https://orcid.org/0000-0003-3055-3389","observed_orcids":["https://orcid.org/0000-0003-3055-3389"]},"institutions":[{"id":"https://openalex.org/I114982161","display_name":"Isfahan University of Medical Sciences","ror":"https://ror.org/04waqzz56","country_code":"IR","type":"education","lineage":["https://openalex.org/I114982161"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mozhde Askari","raw_affiliation_strings":["Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran"],"raw_orcid":"https://orcid.org/0000-0003-3055-3389","affiliations":[{"raw_affiliation_string":"Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran","institution_ids":["https://openalex.org/I114982161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047391226","display_name":"Zahra Teimouri-Jervekani","orcid":"https://orcid.org/0000-0002-3810-7503","observed_orcids":["https://orcid.org/0000-0002-3810-7503"]},"institutions":[{"id":"https://openalex.org/I114982161","display_name":"Isfahan University of Medical Sciences","ror":"https://ror.org/04waqzz56","country_code":"IR","type":"education","lineage":["https://openalex.org/I114982161"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Zahra Teimouri Jervekani","raw_affiliation_strings":["Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran","institution_ids":["https://openalex.org/I114982161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011715272","display_name":"Shima Kaveh","orcid":"https://orcid.org/0000-0002-2454-805X","observed_orcids":["https://orcid.org/0000-0002-2454-805X"]},"institutions":[{"id":"https://openalex.org/I67388046","display_name":"Gorgan University of Agricultural Sciences and Natural Resources","ror":"https://ror.org/01w6vdf77","country_code":"IR","type":"education","lineage":["https://openalex.org/I67388046"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Shima Kaveh","raw_affiliation_strings":["Faculty of Food Science & Technology, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran"],"raw_orcid":"https://orcid.org/0000-0002-2454-805X","affiliations":[{"raw_affiliation_string":"Faculty of Food Science & Technology, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran","institution_ids":["https://openalex.org/I67388046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070623662","display_name":"Mohammad Kermani\u2010Alghoraishi","orcid":"https://orcid.org/0000-0002-3701-3572","observed_orcids":["https://orcid.org/0000-0002-3701-3572"]},"institutions":[{"id":"https://openalex.org/I114982161","display_name":"Isfahan University of Medical Sciences","ror":"https://ror.org/04waqzz56","country_code":"IR","type":"education","lineage":["https://openalex.org/I114982161"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mohammad Kermanialghoraishi","raw_affiliation_strings":["Interventional Cardiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran"],"raw_orcid":"https://orcid.org/0000-0002-3701-3572","affiliations":[{"raw_affiliation_string":"Interventional Cardiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran","institution_ids":["https://openalex.org/I114982161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000810426","display_name":"Alireza Sadeghi Mahoonak","orcid":"https://orcid.org/0000-0002-7461-1440","observed_orcids":["https://orcid.org/0000-0002-7461-1440"]},"institutions":[{"id":"https://openalex.org/I67388046","display_name":"Gorgan University of Agricultural Sciences and Natural Resources","ror":"https://ror.org/01w6vdf77","country_code":"IR","type":"education","lineage":["https://openalex.org/I67388046"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Alireza Sadeghimahoonak","raw_affiliation_strings":["Department of Food Science and Technology, Gorgan University of Agricultural Sciences, Gorgan, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Food Science and Technology, Gorgan University of Agricultural Sciences, Gorgan, Iran","institution_ids":["https://openalex.org/I67388046"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075190743","display_name":"Masoumeh Sadeghi","orcid":"https://orcid.org/0000-0001-7179-5558","observed_orcids":["https://orcid.org/0000-0001-7179-5558","https://orcid.org/0000-0003-4350-3591","https://orcid.org/0000-0001-9648-4684"]},"institutions":[{"id":"https://openalex.org/I114982161","display_name":"Isfahan University of Medical Sciences","ror":"https://ror.org/04waqzz56","country_code":"IR","type":"education","lineage":["https://openalex.org/I114982161"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Masoumeh Sadeghi","raw_affiliation_strings":["Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran"],"raw_orcid":"https://orcid.org/0000-0001-7179-5558","affiliations":[{"raw_affiliation_string":"Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran","institution_ids":["https://openalex.org/I114982161"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5000810426","https://openalex.org/A5075190743"],"corresponding_institution_ids":["https://openalex.org/I114982161","https://openalex.org/I67388046"],"apc_list":{"value":1500,"currency":"USD","value_usd":1500},"apc_paid":{"value":1500,"currency":"USD","value_usd":1500},"fwci":0.2368,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.39462157,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"5","issue":"1","first_page":"100691","last_page":"100691"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13828","display_name":"Natural Products and Biological Research","score":0.9814000129699707,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13828","display_name":"Natural Products and Biological Research","score":0.9814000129699707,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.015300000086426735,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13479","display_name":"Food Science and Nutritional Studies","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypercholesterolemia","display_name":"hypercholesterolemia","score":0.9769999980926514},{"id":"https://openalex.org/keywords/lipid-profile","display_name":"lipid profile","score":0.996999979019165},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.925000011920929},{"id":"https://openalex.org/keywords/total-cholesterol","display_name":"total cholesterol","score":0.8999999761581421},{"id":"https://openalex.org/keywords/non-hdl-cholesterol","display_name":"non-HDL cholesterol","score":0.9649999737739563},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.8500000238418579},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.9980000257492065},{"id":"https://openalex.org/keywords/herbal-medicine","display_name":"herbal medicine","score":0.628000020980835},{"id":"https://openalex.org/keywords/cardiovascular-risk-reduction","display_name":"cardiovascular risk reduction","score":0.5860000252723694},{"id":"https://openalex.org/keywords/tolerability","display_name":"tolerability","score":0.43299999833106995},{"id":"https://openalex.org/keywords/adverse-effects","display_name":"adverse effects","score":0.5789999961853027},{"id":"https://openalex.org/keywords/coronary-artery-disease-risk","display_name":"coronary artery disease risk","score":0.5320000052452087},{"id":"https://openalex.org/keywords/confirmatory-trials","display_name":"confirmatory trials","score":0.3880000114440918},{"id":"https://openalex.org/keywords/lipid-lowering-effect","display_name":"hypolipidemic effect","score":0.4189999997615814}],"concepts":[{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.5963647365570068},{"id":"https://openalex.org/C2991744798","wikidata":"https://www.wikidata.org/wiki/Q608510","display_name":"Double blind","level":4,"score":0.5541999936103821},{"id":"https://openalex.org/C2778270857","wikidata":"https://www.wikidata.org/wiki/Q2723972","display_name":"Lipid profile","level":3,"score":0.47027307748794556},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.46677297353744507},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.45600637793540955},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.4520573019981384},{"id":"https://openalex.org/C2779120738","wikidata":"https://www.wikidata.org/wiki/Q2711291","display_name":"Familial hypercholesterolemia","level":3,"score":0.4316246509552002},{"id":"https://openalex.org/C94412978","wikidata":"https://www.wikidata.org/wiki/Q103135","display_name":"Hydrolysis","level":2,"score":0.42416155338287354},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.35499143600463867},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.301798552274704},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.24879896640777588},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.23998263478279114},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.09853380918502808},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.07511770725250244},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.05893176794052124}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1016/j.phyplu.2024.100691","doi":"https://doi.org/10.1016/j.phyplu.2024.100691","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.phyplu.2024.100691","pdf_url":null,"source":{"id":"https://openalex.org/S4210212705","display_name":"Phytomedicine Plus","issn_l":"2667-0313","issn":["2667-0313"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phytomedicine Plus","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11808590","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11808590","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phytomed Plus","raw_type":"Text"},{"id":"pmid:39935620","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39935620","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phytomedicine plus : international journal of phytotherapy and phytopharmacology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:aebf03844da0439ba620fa33e18fade1","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/aebf03844da0439ba620fa33e18fade1","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Phytomedicine Plus, Vol 5, Iss 1, Pp 100691- (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.phyplu.2024.100691","doi":"https://doi.org/10.1016/j.phyplu.2024.100691","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.phyplu.2024.100691","pdf_url":null,"source":{"id":"https://openalex.org/S4210212705","display_name":"Phytomedicine Plus","issn_l":"2667-0313","issn":["2667-0313"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phytomedicine Plus","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[{"id":"https://openalex.org/G4755154459","display_name":null,"funder_award_id":"988159","funder_id":"https://openalex.org/F4320327486","funder_display_name":"National Institute for Medical Research Development"}],"funders":[{"id":"https://openalex.org/F4320327486","display_name":"National Institute for Medical Research Development","ror":"https://ror.org/046k81c97"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W203659406","https://openalex.org/W213205482","https://openalex.org/W1938031105","https://openalex.org/W1958022600","https://openalex.org/W1973971405","https://openalex.org/W1975398550","https://openalex.org/W2014979854","https://openalex.org/W2020102416","https://openalex.org/W2036210555","https://openalex.org/W2040435503","https://openalex.org/W2065610115","https://openalex.org/W2082177754","https://openalex.org/W2084744450","https://openalex.org/W2108432873","https://openalex.org/W2132737754","https://openalex.org/W2139121515","https://openalex.org/W2146374426","https://openalex.org/W2154973070","https://openalex.org/W2163149206","https://openalex.org/W2278769514","https://openalex.org/W2619599864","https://openalex.org/W2883752934","https://openalex.org/W2941401442","https://openalex.org/W3006057482","https://openalex.org/W3083152796","https://openalex.org/W3195174875"],"related_works":["https://openalex.org/W101174126","https://openalex.org/W4392299688","https://openalex.org/W2573386908","https://openalex.org/W2346738065","https://openalex.org/W2894981880","https://openalex.org/W4406412595","https://openalex.org/W7019632894","https://openalex.org/W2079962983","https://openalex.org/W2613024039","https://openalex.org/W4382465747"],"abstract_inverted_index":{"Background:":[0],"The":[1,52,138,160,232],"risk":[2,98],"of":[3,34,40,60,145,194,235,277,309,319,332],"coronary":[4],"artery":[5],"disease":[6,341],"in":[7,20,68,208,228,274,281,329],"people":[8],"with":[9,22,70,93,119,289,311],"high":[10,18,323],"serum":[11,24],"cholesterol":[12,170],"is":[13,76],"more":[14],"than":[15],"twice":[16],"as":[17,19],"those":[21],"moderate":[23],"cholesterol.":[25],"Natural":[26],"medicines,":[27],"especially":[28],"herbs,":[29],"have":[30],"been":[31],"the":[32,41,58,125,132,164,192,198,229,278,282,306,315,330,338,345],"focus":[33],"attention":[35],"for":[36,47,99,147,255],"many":[37],"years":[38,92],"because":[39],"desirable":[42],"and":[43,96,131,155,180,187,217,249,258,321],"minimal":[44],"side":[45],"effects":[46,318],"controlling":[48],"blood":[49],"lipids.":[50],"Purpose:":[51],"present":[53],"study":[54,75],"aims":[55],"to":[56,112,191,344],"investigate":[57],"effect":[59],"fenugreek":[61],"hydrolyzed":[62],"protein":[63],"(FHP)":[64],"on":[65,88],"lipid":[66,166,201,279,307],"profile":[67,167,202,280,308],"patients":[69,89,116,310],"mild-to-moderate":[71,94,312],"hypercholesterolemia.":[72,313],"Methods:":[73],"This":[74],"a":[77,106,120,205],"confirmatory,":[78],"triple-blind,":[79],"two-group":[80],"parallel,":[81],"randomized":[82,118],"controlled":[83],"trial,":[84],"phase":[85],"3":[86],"conducted":[87],"aged":[90],"18-65":[91],"hypercholesterolemia":[95],"low":[97,316],"cardiovascular":[100,340],"disease.":[101],"Patients":[102,150],"were":[103,117,151,189,226],"recruited":[104],"from":[105,109],"private":[107],"clinic":[108],"May":[110],"2021":[111],"June":[113],"2021.":[114],"Sixty":[115],"1:1":[121],"allocation":[122],"ratio":[123],"into":[124,337],"FHP":[126,146,261,285,302,320],"group":[127,134,140],"(N":[128,135],"=":[129,136,215],"30)":[130],"placebo":[133],"30).":[137],"intervention":[139,199],"was":[141,163,238,270,286],"administrated":[142],"40":[143],"mg/day":[144],"8":[148,156],"weeks.":[149],"examined":[152],"at":[153],"baseline":[154],"weeks":[157],"after":[158],"randomization.":[159],"primary":[161],"outcome":[162,185],"patient's":[165],"including":[168],"total":[169],"(TC),":[171],"high-density":[172],"lipoprotein":[173,176],"(HDL-c),":[174],"low-density":[175],"(LDL-c),":[177],"triglyceride":[178],"(TG),":[179],"non-HDL-c.":[181],"All":[182],"participants,":[183],"caregivers,":[184],"assessors,":[186],"analyzers":[188],"blind":[190],"type":[193],"intervention.":[195],"Results:":[196],"In":[197],"group,":[200],"improved":[203],"through":[204],"significant":[206,224,272],"reduction":[207],"TC":[209],"(P":[210,214,219],"<":[211,220],"0.001),":[212,221],"LDL-c":[213,264],"0.043),":[216],"non-HDL-c":[218],"but":[222],"no":[223,271],"changes":[225],"observed":[227],"TG":[230],"level.":[231],"mean":[233],"difference":[234],"these":[236,333],"variables":[237],"-10.07":[239],"mg/dl":[240,245,251],"[95":[241,246,252],"%CI:30.84;":[242],"10.70],":[243],"-8.93":[244],"%CI:27.07;":[247],"9.21],":[248],"-10.37":[250],"%CI:32.26;":[253],"11.52]":[254],"TC,":[256],"LDL-c,":[257],"non-HDL-c,":[259],"respectively.":[260],"successfully":[262],"decreased":[263],"level":[265],"by":[266],"7":[267],"%.":[268],"There":[269],"change":[273],"any":[275],"component":[276],"comparison":[283],"group.":[284],"well":[287],"tolerated":[288],"only":[290],"1":[291],"patient":[292],"experiencing":[293],"gastrointestinal":[294],"adverse":[295,317],"manifestations.":[296],"Conclusion:":[297],"These":[298],"findings":[299],"suggest":[300],"that":[301],"administration":[303],"can":[304,326],"improve":[305],"Considering":[314],"patients'":[322],"tolerance,":[324],"it":[325],"be":[327],"considered":[328],"management":[331],"patients,":[334],"who":[335],"fall":[336],"low-risk":[339],"category,":[342],"adjuvant":[343],"main":[346],"therapies.":[347],"Registration":[348],"code:":[349],"IRCT20210125050":[350],"142N1.":[351]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-11-21T00:00:00"}
