{"id":"https://openalex.org/W4404500922","doi":"https://doi.org/10.3390/nu16223921","title":"\u201cOMICS\u201d in Human Milk: Focus on Biological Effects on Bone Homeostasis","display_name":"\u201cOMICS\u201d in Human Milk: Focus on Biological Effects on Bone Homeostasis","publication_year":2024,"publication_date":"2024-11-17","ids":{"openalex":"https://openalex.org/W4404500922","doi":"https://doi.org/10.3390/nu16223921","pmid":"https://pubmed.ncbi.nlm.nih.gov/39599707","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11597255"},"language":"en","primary_location":{"id":"doi:10.3390/nu16223921","doi":"https://doi.org/10.3390/nu16223921","is_oa":true,"landing_page_url":"https://doi.org/10.3390/nu16223921","pdf_url":null,"source":{"id":"https://openalex.org/S110785341","display_name":"Nutrients","issn_l":"2072-6643","issn":["2072-6643"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/nu16223921","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037641962","display_name":"Ilaria Farella","orcid":"https://orcid.org/0000-0003-0002-7396","observed_orcids":["https://orcid.org/0000-0003-0002-7396"]},"institutions":[{"id":"https://openalex.org/I4210136227","display_name":"LUM Jean Monnet University","ror":"https://ror.org/03gskda23","country_code":"IT","type":"education","lineage":["https://openalex.org/I4210136227"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Ilaria Farella","raw_affiliation_strings":["Department of Medicine and Surgery, LUM University, 70010 Casamassima, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Surgery, LUM University, 70010 Casamassima, Italy","institution_ids":["https://openalex.org/I4210136227"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081234141","display_name":"Gabriele D\u2019Amato","orcid":"https://orcid.org/0000-0001-5160-9340","observed_orcids":["https://orcid.org/0000-0001-5160-9340"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gabriele D\u2019Amato","raw_affiliation_strings":["Neonatal Intensive Care Unit, Di Venere Hospital, 70012 Bari, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neonatal Intensive Care Unit, Di Venere Hospital, 70012 Bari, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038986317","display_name":"Andrea Orellana\u2010Manzano","orcid":"https://orcid.org/0000-0002-4393-0297","observed_orcids":["https://orcid.org/0000-0002-4393-0297"]},"institutions":[{"id":"https://openalex.org/I2135383","display_name":"Escuela Superior Politecnica del Litoral","ror":"https://ror.org/04qenc566","country_code":"EC","type":"education","lineage":["https://openalex.org/I2135383"]}],"countries":["EC"],"is_corresponding":false,"raw_author_name":"Andrea Orellana-Manzano","raw_affiliation_strings":["Escuela Superior Polit\u00e9cnica del Litoral, ESPOL, Laboratorio Para Investigaciones Biom\u00e9dicas, Facultad de Ciencias de la Vida (FCV), ESPOL Polytechnic University, Campus Gustavo Galindo Km 30.5 v\u00eda Perimetral, Guayaquil P.O. Box 09-01-5863, Ecuador"],"raw_orcid":"https://orcid.org/0000-0002-4393-0297","affiliations":[{"raw_affiliation_string":"Escuela Superior Polit\u00e9cnica del Litoral, ESPOL, Laboratorio Para Investigaciones Biom\u00e9dicas, Facultad de Ciencias de la Vida (FCV), ESPOL Polytechnic University, Campus Gustavo Galindo Km 30.5 v\u00eda Perimetral, Guayaquil P.O. Box 09-01-5863, Ecuador","institution_ids":["https://openalex.org/I2135383"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106798740","display_name":"Yaritza Segura","orcid":"https://orcid.org/0000-0003-3529-4566","observed_orcids":["https://orcid.org/0000-0003-3529-4566"]},"institutions":[{"id":"https://openalex.org/I2135383","display_name":"Escuela Superior Politecnica del Litoral","ror":"https://ror.org/04qenc566","country_code":"EC","type":"education","lineage":["https://openalex.org/I2135383"]}],"countries":["EC"],"is_corresponding":false,"raw_author_name":"Yaritza Segura","raw_affiliation_strings":["Escuela Superior Polit\u00e9cnica del Litoral, ESPOL, Laboratorio Para Investigaciones Biom\u00e9dicas, Facultad de Ciencias de la Vida (FCV), ESPOL Polytechnic University, Campus Gustavo Galindo Km 30.5 v\u00eda Perimetral, Guayaquil P.O. Box 09-01-5863, Ecuador"],"raw_orcid":"https://orcid.org/0000-0003-3529-4566","affiliations":[{"raw_affiliation_string":"Escuela Superior Polit\u00e9cnica del Litoral, ESPOL, Laboratorio Para Investigaciones Biom\u00e9dicas, Facultad de Ciencias de la Vida (FCV), ESPOL Polytechnic University, Campus Gustavo Galindo Km 30.5 v\u00eda Perimetral, Guayaquil P.O. Box 09-01-5863, Ecuador","institution_ids":["https://openalex.org/I2135383"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Rossella Vitale","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210142230","display_name":"Ospedale Pediatrico Giovanni XXIII","ror":"https://ror.org/03nszce13","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210095088","https://openalex.org/I4210099368","https://openalex.org/I4210117053","https://openalex.org/I4210142230"]},{"id":"https://openalex.org/I5561750","display_name":"University of Bari Aldo Moro","ror":"https://ror.org/027ynra39","country_code":"IT","type":"education","lineage":["https://openalex.org/I5561750"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Rossella Vitale","raw_affiliation_strings":["Giovanni XXIII Pediatric Hospital, University of Bari \u201cA. Moro\u201d, 70124 Bari, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Giovanni XXIII Pediatric Hospital, University of Bari \u201cA. Moro\u201d, 70124 Bari, Italy","institution_ids":["https://openalex.org/I4210142230","https://openalex.org/I5561750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035728286","display_name":"Maria Lisa Clodoveo","orcid":"https://orcid.org/0000-0002-1717-2197","observed_orcids":["https://orcid.org/0000-0002-1717-2197"]},"institutions":[{"id":"https://openalex.org/I5561750","display_name":"University of Bari Aldo Moro","ror":"https://ror.org/027ynra39","country_code":"IT","type":"education","lineage":["https://openalex.org/I5561750"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maria Lisa Clodoveo","raw_affiliation_strings":["Interdisciplinary Department of Medicine, School of Medicine, University of Bari \u201cA. Moro\u201d, 70100 Bari, Italy"],"raw_orcid":"https://orcid.org/0000-0002-1717-2197","affiliations":[{"raw_affiliation_string":"Interdisciplinary Department of Medicine, School of Medicine, University of Bari \u201cA. Moro\u201d, 70100 Bari, Italy","institution_ids":["https://openalex.org/I5561750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031658756","display_name":"Filomena Corbo","orcid":"https://orcid.org/0000-0002-6951-1103","observed_orcids":["https://orcid.org/0000-0002-6951-1103"]},"institutions":[{"id":"https://openalex.org/I5561750","display_name":"University of Bari Aldo Moro","ror":"https://ror.org/027ynra39","country_code":"IT","type":"education","lineage":["https://openalex.org/I5561750"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Filomena Corbo","raw_affiliation_strings":["Department of Pharmacy-Drug Sciences, University of Bari \u201cA. Moro\u201d, 70125 Bari, Italy"],"raw_orcid":"https://orcid.org/0000-0002-6951-1103","affiliations":[{"raw_affiliation_string":"Department of Pharmacy-Drug Sciences, University of Bari \u201cA. Moro\u201d, 70125 Bari, Italy","institution_ids":["https://openalex.org/I5561750"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030655484","display_name":"Maria Felicia Faienza","orcid":"https://orcid.org/0000-0002-1899-8337","observed_orcids":["https://orcid.org/0000-0002-1899-8337"]},"institutions":[{"id":"https://openalex.org/I5561750","display_name":"University of Bari Aldo Moro","ror":"https://ror.org/027ynra39","country_code":"IT","type":"education","lineage":["https://openalex.org/I5561750"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Maria Felicia Faienza","raw_affiliation_strings":["Pediatric Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari \u201cA.Moro\u201d, 70124 Bari, Italy"],"raw_orcid":"https://orcid.org/0000-0002-1899-8337","affiliations":[{"raw_affiliation_string":"Pediatric Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari \u201cA.Moro\u201d, 70124 Bari, Italy","institution_ids":["https://openalex.org/I5561750"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5030655484"],"corresponding_institution_ids":["https://openalex.org/I5561750"],"apc_list":{"value":2900,"currency":"CHF","value_usd":3296},"apc_paid":{"value":2900,"currency":"CHF","value_usd":3296},"fwci":0.5357,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.46536495,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"16","issue":"22","first_page":"3921","last_page":"3921"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11294","display_name":"Infant Nutrition and Health","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11294","display_name":"Infant Nutrition and Health","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10979","display_name":"Breastfeeding Practices and Influences","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11561","display_name":"Protein Hydrolysis and Bioactive Peptides","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-milk","display_name":"breast milk","score":0.9959999918937683},{"id":"https://openalex.org/keywords/bone-homeostasis","display_name":"bone homeostasis","score":0.9900000095367432},{"id":"https://openalex.org/keywords/skeletal-development","display_name":"skeletal development","score":0.6489999890327454},{"id":"https://openalex.org/keywords/casein","display_name":"casein","score":0.6439999938011169},{"id":"https://openalex.org/keywords/whey-protein","display_name":"whey protein","score":0.9819999933242798},{"id":"https://openalex.org/keywords/long-chain-polyunsaturated-fatty-acids","display_name":"long-chain polyunsaturated fatty acids","score":0.9399999976158142},{"id":"https://openalex.org/keywords/docosahexaenoic-acid","display_name":"docosahexaenoic acid","score":0.9940000176429749},{"id":"https://openalex.org/keywords/human-milk-oligosaccharides","display_name":"human milk oligosaccharides","score":0.9890000224113464},{"id":"https://openalex.org/keywords/prebiotics","display_name":"prebiotics","score":0.7870000004768372},{"id":"https://openalex.org/keywords/calcium-absorption","display_name":"calcium absorption","score":0.7390000224113464},{"id":"https://openalex.org/keywords/osteogenic-differentiation","display_name":"osteogenic differentiation","score":0.8759999871253967},{"id":"https://openalex.org/keywords/osteoclast-activity","display_name":"osteoclast activity","score":0.9789999723434448},{"id":"https://openalex.org/keywords/insulin-like-growth-factor-i","display_name":"insulin-like growth factor I","score":0.9620000123977661},{"id":"https://openalex.org/keywords/leptin","display_name":"leptin","score":1.0},{"id":"https://openalex.org/keywords/adiponectin","display_name":"adiponectin","score":1.0},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.9800000190734863},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.871999979019165},{"id":"https://openalex.org/keywords/infant-nutrition","display_name":"infant nutrition","score":0.593999981880188},{"id":"https://openalex.org/keywords/bone-mineralization","display_name":"bone mineralization","score":0.7210000157356262}],"concepts":[{"id":"https://openalex.org/C192209626","wikidata":"https://www.wikidata.org/wiki/Q190909","display_name":"Focus (optics)","level":2,"score":0.546909511089325},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.477088063955307},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.46015408635139465},{"id":"https://openalex.org/C63645605","wikidata":"https://www.wikidata.org/wiki/Q103191","display_name":"Homeostasis","level":2,"score":0.45577147603034973},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.38264843821525574},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.18987467885017395},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001846","descriptor_name":"Bone Development","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006706","descriptor_name":"Homeostasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007334","descriptor_name":"Insulin-Like Growth Factor I","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008895","descriptor_name":"Milk, Human","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D009844","descriptor_name":"Oligosaccharides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D015519","descriptor_name":"Bone Density","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.3390/nu16223921","doi":"https://doi.org/10.3390/nu16223921","is_oa":true,"landing_page_url":"https://doi.org/10.3390/nu16223921","pdf_url":null,"source":{"id":"https://openalex.org/S110785341","display_name":"Nutrients","issn_l":"2072-6643","issn":["2072-6643"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11597255","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11597255","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11597255/pdf/nutrients-16-03921.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"Text"},{"id":"pmid:39599707","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39599707","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"Journal Article"},{"id":"pmh:oai:ricerca.uniba.it:11586/522700","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/11586/522700","pdf_url":"https://ricerca.uniba.it/bitstream/11586/522700/1/nutrients-16-03921-v2.pdf","source":{"id":"https://openalex.org/S4377196296","display_name":"CINECA IRIS Institutional Research Information System (University of Bari Aldo Moro)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I5561750","host_organization_name":"University of Bari Aldo Moro","host_organization_lineage":["https://openalex.org/I5561750"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.3390/nu16223921","doi":"https://doi.org/10.3390/nu16223921","is_oa":true,"landing_page_url":"https://doi.org/10.3390/nu16223921","pdf_url":null,"source":{"id":"https://openalex.org/S110785341","display_name":"Nutrients","issn_l":"2072-6643","issn":["2072-6643"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8048999905586243},{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.5666999816894531}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4404500922.pdf","grobid_xml":"https://content.openalex.org/works/W4404500922.grobid-xml"},"referenced_works_count":147,"referenced_works":["https://openalex.org/W1516782514","https://openalex.org/W1561443084","https://openalex.org/W1600636848","https://openalex.org/W1775857285","https://openalex.org/W1827847463","https://openalex.org/W1831856735","https://openalex.org/W1919759535","https://openalex.org/W1922278707","https://openalex.org/W1937008441","https://openalex.org/W1945678278","https://openalex.org/W1963101030","https://openalex.org/W1964341467","https://openalex.org/W1965979895","https://openalex.org/W1970228362","https://openalex.org/W1977734308","https://openalex.org/W1981009974","https://openalex.org/W1990554423","https://openalex.org/W1993382545","https://openalex.org/W2001610144","https://openalex.org/W2001723903","https://openalex.org/W2007454130","https://openalex.org/W2007634497","https://openalex.org/W2012373487","https://openalex.org/W2013597860","https://openalex.org/W2017055384","https://openalex.org/W2017216400","https://openalex.org/W2020365931","https://openalex.org/W2020911494","https://openalex.org/W2024698696","https://openalex.org/W2031410036","https://openalex.org/W2033509297","https://openalex.org/W2035401350","https://openalex.org/W2038328989","https://openalex.org/W2038582444","https://openalex.org/W2048698360","https://openalex.org/W2051219239","https://openalex.org/W2052884179","https://openalex.org/W2054143788","https://openalex.org/W2056052724","https://openalex.org/W2057049750","https://openalex.org/W2060752547","https://openalex.org/W2063506958","https://openalex.org/W2068877511","https://openalex.org/W2073712321","https://openalex.org/W2080177399","https://openalex.org/W2080438822","https://openalex.org/W2080850527","https://openalex.org/W2081839771","https://openalex.org/W2083517334","https://openalex.org/W2093684733","https://openalex.org/W2098109822","https://openalex.org/W2099625831","https://openalex.org/W2099631609","https://openalex.org/W2100763317","https://openalex.org/W2102651936","https://openalex.org/W2114307472","https://openalex.org/W2117145054","https://openalex.org/W2120233186","https://openalex.org/W2123690308","https://openalex.org/W2124370496","https://openalex.org/W2126295255","https://openalex.org/W2129314505","https://openalex.org/W2129882048","https://openalex.org/W2135433308","https://openalex.org/W2136666074","https://openalex.org/W2138906762","https://openalex.org/W2145409841","https://openalex.org/W2145459373","https://openalex.org/W2147714695","https://openalex.org/W2147747389","https://openalex.org/W2157183728","https://openalex.org/W2158048451","https://openalex.org/W2162962110","https://openalex.org/W2163022331","https://openalex.org/W2164602685","https://openalex.org/W2169804397","https://openalex.org/W2172396054","https://openalex.org/W2291184947","https://openalex.org/W2300045235","https://openalex.org/W2316764483","https://openalex.org/W2325088487","https://openalex.org/W2350379238","https://openalex.org/W2394748971","https://openalex.org/W2398374545","https://openalex.org/W2517138696","https://openalex.org/W2538850214","https://openalex.org/W2556125626","https://openalex.org/W2571897146","https://openalex.org/W2583150154","https://openalex.org/W2588510615","https://openalex.org/W2592371756","https://openalex.org/W2594652795","https://openalex.org/W2598642800","https://openalex.org/W2599507001","https://openalex.org/W2606663695","https://openalex.org/W2618894344","https://openalex.org/W2687757105","https://openalex.org/W2746104019","https://openalex.org/W2775025573","https://openalex.org/W2783957908","https://openalex.org/W2784870447","https://openalex.org/W2786091056","https://openalex.org/W2789440232","https://openalex.org/W2791389853","https://openalex.org/W2792935804","https://openalex.org/W2806084892","https://openalex.org/W2890920242","https://openalex.org/W2892139323","https://openalex.org/W2902974392","https://openalex.org/W2940538347","https://openalex.org/W2948811505","https://openalex.org/W2965704893","https://openalex.org/W2966176178","https://openalex.org/W2967736887","https://openalex.org/W2979300097","https://openalex.org/W2981958174","https://openalex.org/W3006822025","https://openalex.org/W3012024600","https://openalex.org/W3012679311","https://openalex.org/W3026977153","https://openalex.org/W3039404330","https://openalex.org/W3092277963","https://openalex.org/W3111919687","https://openalex.org/W3126936405","https://openalex.org/W3134112322","https://openalex.org/W3173894909","https://openalex.org/W3187990360","https://openalex.org/W3204263813","https://openalex.org/W4210287253","https://openalex.org/W4220774638","https://openalex.org/W4250292426","https://openalex.org/W4254913758","https://openalex.org/W4283075491","https://openalex.org/W4297348062","https://openalex.org/W4317721874","https://openalex.org/W4376106517","https://openalex.org/W4379053285","https://openalex.org/W4387345343","https://openalex.org/W4387666863","https://openalex.org/W4387893378","https://openalex.org/W4391138242","https://openalex.org/W4396675119","https://openalex.org/W4396815026","https://openalex.org/W4399430871","https://openalex.org/W4399817335","https://openalex.org/W4402933689","https://openalex.org/W6678561940"],"related_works":["https://openalex.org/W2038328989","https://openalex.org/W2788759511","https://openalex.org/W4411718209","https://openalex.org/W4320921766","https://openalex.org/W7214896762","https://openalex.org/W2204704372","https://openalex.org/W4410525395","https://openalex.org/W3148171405","https://openalex.org/W4400176880","https://openalex.org/W4396931787"],"abstract_inverted_index":{"Human":[0],"milk":[1,96,146],"(HM)":[2],"is":[3],"a":[4,190],"complex":[5],"biofluid":[6],"rich":[7],"in":[8,19,114,144,173,188],"nutrients":[9],"and":[10,25,37,52,57,63,68,90,105,124,134,155,160,179,227],"bioactive":[11],"compounds":[12],"essential":[13],"for":[14],"infant":[15,130,192,228],"health.":[16,38,230],"Recent":[17],"advances":[18],"omics":[20,212],"technologies-such":[21],"as":[22,100,117],"proteomics,":[23],"metabolomics,":[24],"transcriptomics-have":[26],"shed":[27],"light":[28],"on":[29,34,54],"the":[30,42,168,219],"influence":[31,157],"of":[32,44,170],"HM":[33,46,225],"bone":[35,55,72,84,110,135,161,180,197,229],"development":[36,198],"This":[39],"review":[40],"discusses":[41],"impact":[43],"various":[45],"components,":[47],"including":[48],"proteins,":[49],"lipids,":[50],"carbohydrates,":[51],"hormones,":[53],"metabolism":[56],"skeletal":[58,241],"growth.":[59],"Proteins":[60],"like":[61,78,177],"casein":[62],"whey":[64],"promote":[65],"calcium":[66,106],"absorption":[67],"osteoblast":[69],"differentiation,":[70],"supporting":[71],"mineralization.":[73,111],"Long-chain":[74],"polyunsaturated":[75],"fatty":[76],"acids":[77],"docosahexaenoic":[79],"acid":[80],"(DHA)":[81],"contribute":[82],"to":[83,129,216,239],"health":[85,104,242],"by":[86,199],"modulating":[87],"inflammatory":[88],"pathways":[89],"regulating":[91,174],"osteoclast":[92],"activity.":[93],"Additionally,":[94],"human":[95],"oligosaccharides":[97],"(HMOs)":[98],"act":[99],"prebiotics,":[101],"improving":[102],"gut":[103,193],"bioavailability":[107],"while":[108,153],"influencing":[109,196],"Hormones":[112],"present":[113],"HM,":[115],"such":[116],"insulin-like":[118],"growth":[119],"factor":[120],"1":[121],"(IGF-1),":[122],"leptin,":[123],"adiponectin,":[125],"have":[126,165],"been":[127],"linked":[128],"growth,":[131],"body":[132],"composition,":[133,226],"density.":[136],"Research":[137],"has":[138],"shown":[139],"that":[140],"higher":[141],"IGF-1":[142],"levels":[143],"breast":[145],"are":[147,206,214],"associated":[148],"with":[149],"increased":[150],"weight":[151],"gain,":[152],"leptin":[154],"adiponectin":[156],"fat":[158],"mass":[159],"metabolism.":[162],"Emerging":[163],"studies":[164,210],"also":[166],"highlighted":[167],"role":[169,187],"microRNAs":[171],"(miRNAs)":[172],"key":[175],"processes":[176],"adipogenesis":[178],"homeostasis.":[181],"Furthermore,":[182],"microbiome-focused":[183],"techniques":[184],"reveal":[185],"HM's":[186],"establishing":[189],"balanced":[191],"microbiota,":[194],"indirectly":[195],"enhancing":[200],"nutrient":[201],"absorption.":[202],"Although":[203],"current":[204],"findings":[205],"promising,":[207],"comprehensive":[208],"longitudinal":[209],"integrating":[211],"approaches":[213],"needed":[215],"fully":[217],"understand":[218],"intricate":[220],"relationships":[221],"among":[222],"maternal":[223],"diet,":[224],"Bridging":[231],"these":[232],"gaps":[233],"could":[234],"offer":[235],"novel":[236],"dietary":[237],"strategies":[238],"optimize":[240],"during":[243],"infancy,":[244],"advancing":[245],"early-life":[246],"nutrition":[247],"science.":[248]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-11-20T00:00:00"}