{"id":"https://openalex.org/W4404485750","doi":"https://doi.org/10.3390/ijms252212364","title":"L-Arginine and Intermittent Hypoxia Are Stress-Limiting Factors in Male Wistar Rat Models","display_name":"L-Arginine and Intermittent Hypoxia Are Stress-Limiting Factors in Male Wistar Rat Models","publication_year":2024,"publication_date":"2024-11-18","ids":{"openalex":"https://openalex.org/W4404485750","doi":"https://doi.org/10.3390/ijms252212364","pmid":"https://pubmed.ncbi.nlm.nih.gov/39596428","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11595073"},"language":"en","primary_location":{"id":"doi:10.3390/ijms252212364","doi":"https://doi.org/10.3390/ijms252212364","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms252212364","pdf_url":"https://www.mdpi.com/1422-0067/25/22/12364/pdf?version=1731921714","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1422-0067/25/22/12364/pdf?version=1731921714","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018071734","display_name":"Natalia Kurhaluk","orcid":"https://orcid.org/0000-0002-4669-1092","observed_orcids":["https://orcid.org/0000-0002-4669-1092"]},"institutions":[{"id":"https://openalex.org/I4210092219","display_name":"Uniwersytet Pomorski w S\u0142upsku","ror":"https://ror.org/00h8nar58","country_code":"PL","type":"education","lineage":["https://openalex.org/I4210092219"]}],"countries":["PL"],"is_corresponding":true,"raw_author_name":"Natalia Kurhaluk","raw_affiliation_strings":["Department of Animal Physiology, Institute of Biology, Pomeranian University in S\u0142upsk, Arciszewski St. 22b, PL 76-200 S\u0142upsk, Poland"],"raw_orcid":"https://orcid.org/0000-0002-4669-1092","affiliations":[{"raw_affiliation_string":"Department of Animal Physiology, Institute of Biology, Pomeranian University in S\u0142upsk, Arciszewski St. 22b, PL 76-200 S\u0142upsk, Poland","institution_ids":["https://openalex.org/I4210092219"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037337106","display_name":"\u041e\u043b\u0435\u043a\u0441\u0430\u043d\u0434\u0440 \u0412\u0430\u0441\u0438\u043b\u044c\u043e\u0432\u0438\u0447 \u041b\u0443\u043a\u0430\u0448","orcid":"https://orcid.org/0000-0003-2702-6430","observed_orcids":["https://orcid.org/0000-0003-2702-6430"]},"institutions":[{"id":"https://openalex.org/I4210112659","display_name":"T.H. Shevchenko National University \"Chernihiv Colehium\"","ror":"https://ror.org/024ykzk09","country_code":"UA","type":"education","lineage":["https://openalex.org/I4210112659"]}],"countries":["UA"],"is_corresponding":false,"raw_author_name":"Oleksandr Lukash","raw_affiliation_strings":["Department of Ecology, Geography and Nature Management, T.H. Shevchenko National University \u201cChernihiv Colehium\u201d, Hetmana Polubotka St. 53, 14013 Chernihiv, Ukraine"],"raw_orcid":"https://orcid.org/0000-0003-2702-6430","affiliations":[{"raw_affiliation_string":"Department of Ecology, Geography and Nature Management, T.H. Shevchenko National University \u201cChernihiv Colehium\u201d, Hetmana Polubotka St. 53, 14013 Chernihiv, Ukraine","institution_ids":["https://openalex.org/I4210112659"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038576894","display_name":"Piotr Kami\u0144ski","orcid":"https://orcid.org/0000-0003-1978-6018","observed_orcids":["https://orcid.org/0000-0003-1978-6018"]},"institutions":[{"id":"https://openalex.org/I3019271933","display_name":"Nicolaus Copernicus University","ror":"https://ror.org/0102mm775","country_code":"PL","type":"education","lineage":["https://openalex.org/I3019271933"]},{"id":"https://openalex.org/I4210148386","display_name":"Collegium Medicum in Bydgoszcz","ror":"https://ror.org/04c5jwj47","country_code":"PL","type":"education","lineage":["https://openalex.org/I3019271933","https://openalex.org/I4210148386"]},{"id":"https://openalex.org/I46305939","display_name":"University of Zielona G\u00f3ra","ror":"https://ror.org/04fzm7v55","country_code":"PL","type":"education","lineage":["https://openalex.org/I46305939"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Piotr Kami\u0144ski","raw_affiliation_strings":["Department of Biotechnology, Faculty of Biological Sciences, Institute of Biological Sciences, University of Zielona G\u00f3ra, Prof. Z. Szafran St. 1, PL 65-516 Zielona G\u00f3ra, Poland","Department of Ecology and Environmental Protection, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toru\u0144, M. Sk\u0142odowska-Curie St. 9, PL 85-094 Bydgoszcz, Poland","Department of Medical Biology and Biochemistry, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toru\u0144, M. Sk\u0142odowska-Curie St. 9, PL 85-094 Bydgoszcz, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Faculty of Biological Sciences, Institute of Biological Sciences, University of Zielona G\u00f3ra, Prof. Z. Szafran St. 1, PL 65-516 Zielona G\u00f3ra, Poland","institution_ids":["https://openalex.org/I46305939"]},{"raw_affiliation_string":"Department of Ecology and Environmental Protection, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toru\u0144, M. Sk\u0142odowska-Curie St. 9, PL 85-094 Bydgoszcz, Poland","institution_ids":["https://openalex.org/I3019271933","https://openalex.org/I4210148386"]},{"raw_affiliation_string":"Department of Medical Biology and Biochemistry, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toru\u0144, M. Sk\u0142odowska-Curie St. 9, PL 85-094 Bydgoszcz, Poland","institution_ids":["https://openalex.org/I3019271933","https://openalex.org/I4210148386"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028875714","display_name":"\u0413\u0430\u043b\u0438\u043d\u0430 \u041c\u0438\u0445\u0430\u0439\u043b\u0456\u0432\u043d\u0430 \u0422\u043a\u0430\u0447\u0435\u043d\u043a\u043e","orcid":"https://orcid.org/0000-0003-3951-9005","observed_orcids":["https://orcid.org/0000-0003-3951-9005"]},"institutions":[{"id":"https://openalex.org/I4210092219","display_name":"Uniwersytet Pomorski w S\u0142upsku","ror":"https://ror.org/00h8nar58","country_code":"PL","type":"education","lineage":["https://openalex.org/I4210092219"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Halina Tkaczenko","raw_affiliation_strings":["Department of Animal Physiology, Institute of Biology, Pomeranian University in S\u0142upsk, Arciszewski St. 22b, PL 76-200 S\u0142upsk, Poland"],"raw_orcid":"https://orcid.org/0000-0003-3951-9005","affiliations":[{"raw_affiliation_string":"Department of Animal Physiology, Institute of Biology, Pomeranian University in S\u0142upsk, Arciszewski St. 22b, PL 76-200 S\u0142upsk, Poland","institution_ids":["https://openalex.org/I4210092219"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5018071734"],"corresponding_institution_ids":["https://openalex.org/I4210092219"],"apc_list":{"value":2900,"currency":"CHF","value_usd":3296},"apc_paid":{"value":2900,"currency":"CHF","value_usd":3296},"fwci":1.8667,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.82622506,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"25","issue":"22","first_page":"12364","last_page":"12364"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.5059000253677368,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.5059000253677368,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":0.15950000286102295,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.08370000123977661,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/l-arginine","display_name":"L-arginine","score":1.0},{"id":"https://openalex.org/keywords/intermittent-hypoxia-training","display_name":"intermittent hypoxia training","score":0.9660000205039978},{"id":"https://openalex.org/keywords/acute-stress","display_name":"acute stress","score":0.968999981880188},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.7350000143051147},{"id":"https://openalex.org/keywords/nitric-oxide-synthase","display_name":"nitric oxide synthase","score":0.9350000023841858},{"id":"https://openalex.org/keywords/catecholamines","display_name":"catecholamines","score":0.9660000205039978},{"id":"https://openalex.org/keywords/epinephrine","display_name":"epinephrine","score":0.7639999985694885},{"id":"https://openalex.org/keywords/norepinephrine","display_name":"norepinephrine","score":0.9980000257492065},{"id":"https://openalex.org/keywords/dopamine","display_name":"dopamine","score":0.8259999752044678},{"id":"https://openalex.org/keywords/acetylcholine","display_name":"acetylcholine","score":0.8859999775886536},{"id":"https://openalex.org/keywords/acetylcholinesterase","display_name":"acetylcholinesterase","score":0.9980000257492065},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.9129999876022339},{"id":"https://openalex.org/keywords/mitochondrial-oxidative-phosphorylation","display_name":"mitochondrial oxidative phosphorylation","score":0.925000011920929},{"id":"https://openalex.org/keywords/nad-dependent-oxidation","display_name":"NAD-dependent oxidation","score":0.8379999995231628},{"id":"https://openalex.org/keywords/succinate-oxidation","display_name":"succinate oxidation","score":0.9430000185966492},{"id":"https://openalex.org/keywords/sympathoadrenal-system","display_name":"sympathoadrenal system","score":0.75},{"id":"https://openalex.org/keywords/hypoxia-adaptation","display_name":"hypoxia adaptation","score":0.6819999814033508},{"id":"https://openalex.org/keywords/liver","display_name":"liver","score":0.42399999499320984},{"id":"https://openalex.org/keywords/blood","display_name":"blood","score":0.4449999928474426}],"concepts":[{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.7313728928565979},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6515321731567383},{"id":"https://openalex.org/C2777468819","wikidata":"https://www.wikidata.org/wiki/Q173670","display_name":"Arginine","level":3,"score":0.6451480388641357},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6395478844642639},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6154477000236511},{"id":"https://openalex.org/C2775910092","wikidata":"https://www.wikidata.org/wiki/Q180623","display_name":"Acetylcholine","level":2,"score":0.5221883654594421},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.49115821719169617},{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.48706844449043274},{"id":"https://openalex.org/C57600042","wikidata":"https://www.wikidata.org/wiki/Q227564","display_name":"Oxidative phosphorylation","level":2,"score":0.4777913987636566},{"id":"https://openalex.org/C2778816929","wikidata":"https://www.wikidata.org/wiki/Q22676679","display_name":"Acetylcholinesterase","level":3,"score":0.4342150390148163},{"id":"https://openalex.org/C22885893","wikidata":"https://www.wikidata.org/wiki/Q4862743","display_name":"Cholinergic","level":2,"score":0.42442992329597473},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3175380825996399},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.28059831261634827},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.18621987104415894},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17092368006706238},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15889635682106018},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.0688706636428833},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000860","descriptor_name":"Hypoxia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001120","descriptor_name":"Arginine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002395","descriptor_name":"Catecholamines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010085","descriptor_name":"Oxidative Phosphorylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013312","descriptor_name":"Stress, Physiological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015227","descriptor_name":"Lipid Peroxidation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3390/ijms252212364","doi":"https://doi.org/10.3390/ijms252212364","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms252212364","pdf_url":"https://www.mdpi.com/1422-0067/25/22/12364/pdf?version=1731921714","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11595073","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11595073","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11595073/pdf/ijms-25-12364.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Mol Sci","raw_type":"Text"},{"id":"pmid:39596428","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39596428","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of molecular sciences","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3390/ijms252212364","doi":"https://doi.org/10.3390/ijms252212364","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms252212364","pdf_url":"https://www.mdpi.com/1422-0067/25/22/12364/pdf?version=1731921714","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8199999928474426,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4404485750.pdf","grobid_xml":"https://content.openalex.org/works/W4404485750.grobid-xml"},"referenced_works_count":74,"referenced_works":["https://openalex.org/W256859034","https://openalex.org/W1458987816","https://openalex.org/W1575852352","https://openalex.org/W1583094119","https://openalex.org/W1590457525","https://openalex.org/W1853393224","https://openalex.org/W1965039372","https://openalex.org/W1967263782","https://openalex.org/W1971048984","https://openalex.org/W1980785904","https://openalex.org/W2004713885","https://openalex.org/W2005970828","https://openalex.org/W2007617786","https://openalex.org/W2012539632","https://openalex.org/W2015314388","https://openalex.org/W2031205373","https://openalex.org/W2035541558","https://openalex.org/W2035714184","https://openalex.org/W2050965064","https://openalex.org/W2056112038","https://openalex.org/W2074595259","https://openalex.org/W2087658883","https://openalex.org/W2095609673","https://openalex.org/W2104168812","https://openalex.org/W2128635872","https://openalex.org/W2130121105","https://openalex.org/W2136779506","https://openalex.org/W2142240863","https://openalex.org/W2169887727","https://openalex.org/W2171107203","https://openalex.org/W2218507208","https://openalex.org/W2287035026","https://openalex.org/W2313473114","https://openalex.org/W2317953209","https://openalex.org/W2398452987","https://openalex.org/W2414274852","https://openalex.org/W2417713558","https://openalex.org/W2419080797","https://openalex.org/W2428636924","https://openalex.org/W2466654894","https://openalex.org/W2538544078","https://openalex.org/W2593988580","https://openalex.org/W2614739342","https://openalex.org/W2620702995","https://openalex.org/W2736703971","https://openalex.org/W2761697926","https://openalex.org/W2784297905","https://openalex.org/W2794716305","https://openalex.org/W2805954559","https://openalex.org/W2809261180","https://openalex.org/W2882999515","https://openalex.org/W2898849930","https://openalex.org/W2913403920","https://openalex.org/W2954807358","https://openalex.org/W2980378167","https://openalex.org/W2988471964","https://openalex.org/W3027521749","https://openalex.org/W3045640063","https://openalex.org/W3085556079","https://openalex.org/W3110044782","https://openalex.org/W3136533222","https://openalex.org/W3164827917","https://openalex.org/W3166618611","https://openalex.org/W3190014273","https://openalex.org/W3205425413","https://openalex.org/W4220833414","https://openalex.org/W4220999636","https://openalex.org/W4229020907","https://openalex.org/W4306850900","https://openalex.org/W4307302042","https://openalex.org/W4366775557","https://openalex.org/W4376630459","https://openalex.org/W4388693212","https://openalex.org/W4399483516"],"related_works":["https://openalex.org/W2432720859","https://openalex.org/W2411120760","https://openalex.org/W2128066880","https://openalex.org/W2417494080","https://openalex.org/W2080178582","https://openalex.org/W7096903802","https://openalex.org/W4387578856","https://openalex.org/W4399483516","https://openalex.org/W4401113200","https://openalex.org/W2498234962"],"abstract_inverted_index":{"The":[0,98,135,244],"aim":[1],"of":[2,11,34,46,54,86,96,106,123,133,137,144,162,167,181,189,200,203,221,233,242,249,264,285,291],"this":[3],"study":[4,40,80],"was":[5,112,119,207,229,236,253],"to":[6,115,174,266],"evaluate":[7],"the":[8,32,43,47,52,71,82,92,104,141,149,160,163,170,178,182,186,190,197,204,218,223,240,277,282,289],"combined":[9],"effects":[10,85],"L-arginine,":[12],"intermittent":[13],"hypoxia":[14,267],"training":[15],"(IHT),":[16],"and":[17,31,60,62,89,94,118,140,216,251,274],"acute":[18],"stress":[19,128,154,175],"on":[20,51,70],"oxygen-dependent":[21,286],"processes":[22,287],"in":[23,77,91,109,148,153,193,213,217,246,258],"rats,":[24],"including":[25],"mitochondrial":[26,150],"oxidative":[27],"phosphorylation,":[28],"microsomal":[29],"oxidation,":[30,117],"intensity":[33],"lipoperoxidation":[35,214],"processes.":[36],"In":[37,196],"addition,":[38],"our":[39],"investigated":[41,81],"how":[42],"modulatory":[44],"effect":[45],"NO":[48,164],"synthase":[49],"mechanism":[50],"concentration":[53,206],"catecholamines":[55],"(CA),":[56],"such":[57],"as":[58],"adrenaline":[59],"noradrenaline,":[61],"their":[63],"biosynthetic":[64],"precursors":[65],"(DOPA,":[66],"dopamine)":[67],"varies":[68],"depending":[69],"cholinergic":[72],"(acetylcholine,":[73],"Ach-acetylcholinesterase,":[74],"AChE)":[75],"status":[76],"rats.":[78,97,195],"This":[79],"protective":[83],"stress-limiting":[84],"L-arginine":[87,102,168,184],"impact":[88],"IHT":[90,171,270,278],"blood":[93,247],"liver":[95],"results":[99],"showed":[100],"that":[101],"promoted":[103],"maintenance":[105],"NAD-dependent":[107,145],"oxidation":[108,139,147],"mitochondria,":[110],"which":[111,235],"detrimental":[113],"compared":[114],"succinate":[116],"accompanied":[120,254],"by":[121,130,239,255,269,295],"depletion":[122],"respiratory":[124,151],"activity":[125,260],"reserves":[126],"under":[127],"induced":[129,156,268],"high":[131],"concentrations":[132,225,248],"CA.":[134],"interdependence":[136],"SC-dependent":[138],"functional":[142],"role":[143],"substrate":[146],"chain":[152],"conditions":[155],"using":[157],"inhibitors":[158],"revealed":[159],"importance":[161],"system.":[165],"Administration":[166],"during":[169],"course":[172],"prior":[173],"exposure":[176],"increased":[177,185],"compensatory":[179,187],"capacity":[180,188,284],"organism.":[183],"sympathoadrenal":[191],"system":[192,290],"stress-exposed":[194],"early":[198],"stages":[199,220,263],"IHT,":[201,222],"modulation":[202],"CA":[205,224,250],"observed":[208],"with":[209],"a":[210,256],"concomitant":[211],"increase":[212,245],"processes,":[215],"final":[219],"increased,":[226],"but":[227],"there":[228],"also":[230],"an":[231],"inhibition":[232],"lipoperoxidation,":[234],"particularly":[237],"enhanced":[238],"administration":[241],"L-arginine.":[243],"ACh":[252],"decrease":[257],"AChE":[259],"at":[261],"different":[262],"adaptation":[265],"(days":[271],"5,":[272],"10,":[273],"14).":[275],"Thus,":[276],"method":[279],"significantly":[280],"mobilises":[281],"reserve":[283],"through":[288],"CA,":[292],"ACh-AChE":[293],"mediated":[294],"nitric":[296],"oxide.":[297]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-11-19T00:00:00"}