{"id":"https://openalex.org/W4404474209","doi":"https://doi.org/10.1111/jce.16500","title":"Pulse Field Ablation of Atrial Fibrillation and Hemolysis\u2014Red Blood Cells Also Demand Our Attention","display_name":"Pulse Field Ablation of Atrial Fibrillation and Hemolysis\u2014Red Blood Cells Also Demand Our Attention","publication_year":2024,"publication_date":"2024-11-17","ids":{"openalex":"https://openalex.org/W4404474209","doi":"https://doi.org/10.1111/jce.16500","pmid":"https://pubmed.ncbi.nlm.nih.gov/39551971"},"language":"en","primary_location":{"id":"doi:10.1111/jce.16500","doi":"https://doi.org/10.1111/jce.16500","is_oa":false,"landing_page_url":"https://doi.org/10.1111/jce.16500","pdf_url":null,"source":{"id":"https://openalex.org/S143832381","display_name":"Journal of Cardiovascular Electrophysiology","issn_l":"1045-3873","issn":["1045-3873","1540-8167"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cardiovascular Electrophysiology","raw_type":"journal-article"},"volume":null,"type":"editorial","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075198444","display_name":"Helge Immo Lehmann","orcid":"https://orcid.org/0000-0003-4379-283X","observed_orcids":["https://orcid.org/0000-0003-4379-283X"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. Immo Lehmann","raw_affiliation_strings":["Division of Cardiovascular Medicine, University of Utah, Salt Lake City, Utah, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Medicine, University of Utah, Salt Lake City, Utah, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059719975","display_name":"Gregory J. Stoddard","orcid":"https://orcid.org/0000-0002-6292-276X","observed_orcids":["https://orcid.org/0000-0002-6292-276X","https://orcid.org/0009-0005-1923-9956"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gregory J. Stoddard","raw_affiliation_strings":["Division of Epidemiology, University of Utah, Salt Lake City, Utah, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Epidemiology, University of Utah, Salt Lake City, Utah, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074809926","display_name":"Ravi Ranjan","orcid":"https://orcid.org/0000-0002-3321-2435","observed_orcids":["https://orcid.org/0000-0002-3321-2435"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ravi Ranjan","raw_affiliation_strings":["Division of Cardiovascular Medicine, University of Utah, Salt Lake City, Utah, USA"],"raw_orcid":"https://orcid.org/0000-0002-3321-2435","affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Medicine, University of Utah, Salt Lake City, Utah, USA","institution_ids":["https://openalex.org/I223532165"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5074809926"],"corresponding_institution_ids":["https://openalex.org/I223532165"],"apc_list":{"value":4290,"currency":"USD","value_usd":4290},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"35","issue":"12","first_page":"2411","last_page":"2413"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.6987000107765198,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.6987000107765198,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11217","display_name":"Cardiac Arrhythmias and Treatments","score":0.29030001163482666,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10598","display_name":"Cardiac pacing and defibrillation studies","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pulsed-field-ablation","display_name":"pulsed field ablation","score":0.9900000095367432},{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"atrial fibrillation","score":0.9940000176429749},{"id":"https://openalex.org/keywords/hemolysis","display_name":"hemolysis","score":0.9739999771118164},{"id":"https://openalex.org/keywords/erythrocytes","display_name":"erythrocytes","score":0.7210000157356262},{"id":"https://openalex.org/keywords/pulmonary-vein-isolation","display_name":"pulmonary vein isolation","score":0.8859999775886536},{"id":"https://openalex.org/keywords/pentaspline-catheter","display_name":"pentaspline catheter","score":0.8050000071525574},{"id":"https://openalex.org/keywords/hemolysis-markers","display_name":"hemolysis markers","score":0.6510000228881836},{"id":"https://openalex.org/keywords/lactate-dehydrogenase","display_name":"lactate dehydrogenase","score":0.8370000123977661},{"id":"https://openalex.org/keywords/bilirubin","display_name":"bilirubin","score":0.9539999961853027},{"id":"https://openalex.org/keywords/kidney-failure","display_name":"renal failure","score":0.7269999980926514},{"id":"https://openalex.org/keywords/ablation-safety","display_name":"ablation safety","score":0.7179999947547913},{"id":"https://openalex.org/keywords/non-thermal-ablation","display_name":"non-thermal ablation","score":0.6079999804496765},{"id":"https://openalex.org/keywords/mitral-isthmus-ablation","display_name":"mitral isthmus ablation","score":0.7509999871253967},{"id":"https://openalex.org/keywords/cavotricuspid-isthmus-ablation","display_name":"cavotricuspid isthmus ablation","score":0.949999988079071}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9336940050125122},{"id":"https://openalex.org/C2779902561","wikidata":"https://www.wikidata.org/wiki/Q471706","display_name":"Hemolysis","level":2,"score":0.8365606069564819},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.767695963382721},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6824806928634644},{"id":"https://openalex.org/C2778902805","wikidata":"https://www.wikidata.org/wiki/Q322177","display_name":"Ablation","level":2,"score":0.6572118997573853},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.581911563873291},{"id":"https://openalex.org/C2780167933","wikidata":"https://www.wikidata.org/wiki/Q1550652","display_name":"Pulse (music)","level":3,"score":0.4245683252811432},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0562894344329834},{"id":"https://openalex.org/C165801399","wikidata":"https://www.wikidata.org/wiki/Q25428","display_name":"Voltage","level":2,"score":0.05352059006690979},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1111/jce.16500","doi":"https://doi.org/10.1111/jce.16500","is_oa":false,"landing_page_url":"https://doi.org/10.1111/jce.16500","pdf_url":null,"source":{"id":"https://openalex.org/S143832381","display_name":"Journal of Cardiovascular Electrophysiology","issn_l":"1045-3873","issn":["1045-3873","1540-8167"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cardiovascular Electrophysiology","raw_type":"journal-article"},{"id":"pmid:39551971","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39551971","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cardiovascular electrophysiology","raw_type":"Editorial"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9922999739646912}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger","score":0.5799999833106995}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2999550239","display_name":null,"funder_award_id":"R01HL142913 and R01HL162353.","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6833990213","display_name":"Myocardial Substrate Driven Mechanistic Insights into Atrial Fibrillation","funder_award_id":"R01HL142913","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000882844","display_name":"Improved Imaging of Fibrosis in Atrial Fibrillation","funder_award_id":"R01HL162353","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W3132769825","https://openalex.org/W3159049481","https://openalex.org/W4214726821","https://openalex.org/W4289943466","https://openalex.org/W4390590265","https://openalex.org/W4396978673","https://openalex.org/W4397032255","https://openalex.org/W4400422937","https://openalex.org/W4403377131","https://openalex.org/W4403510003","https://openalex.org/W4403893216"],"related_works":["https://openalex.org/W4410620897","https://openalex.org/W4402065363","https://openalex.org/W7155404473","https://openalex.org/W4410620782","https://openalex.org/W7167664124","https://openalex.org/W4398767581","https://openalex.org/W4396979320","https://openalex.org/W4416202561","https://openalex.org/W4414055927","https://openalex.org/W7138200345"],"abstract_inverted_index":{"In":[0,23,312,334,526],"this":[1,207,231,369,551,578,1027],"issue":[2],"of":[3,6,26,66,71,92,104,108,126,140,197,241,268,283,316,324,330,377,396,426,481,490,495,508,548,557,565,596,623,628,645,653,660,666,699,739,751,821,849,871,875,939,957,994,1000,1026,1052],"the":[4,37,64,102,193,239,253,273,279,328,375,392,404,423,450,460,479,488,493,506,519,523,527,554,563,566,591,597,618,621,626,651,658,664,680,719,737,747,752,803,822,825,872,876,881,898,937,955,992,1024,1050],"journal":[5],"cardiovascular":[7],"electrophysiology,":[8],"Stojadinovi\u0107":[9,364,722,945],"et":[10,289,365,723,946],"al.":[11,290,366,724,947],"[1]":[12,367,725],"try":[13],"to":[14,169,178,310,327,347,387,410,443,459,465,503,656,689,727,730,794,839,868,888,904,913,925,974,979,987,1014,1038,1049,1067],"further":[15,292,734],"characterize":[16],"pulse":[17,164],"field":[18,165,757],"ablation":[19,125,201,308,345,595,745,760,798,831,916],"(PFA)":[20],"associated":[21],"hemolysis.":[22,94,549],"a":[24,60,88,182,198,297,313,321,380,399,482,545,581,641,654,811,819,857,951,969,1036],"series":[25],"60":[27],"patients":[28,303,318,341,535,742],"with":[29,34,492,510,590,733,936],"atrial":[30,804],"fibrillation":[31],"(AF),":[32],"treated":[33],"PFA":[35,67,114,174,242,275,331,372,469,496,511,558,610,629,893,949,975,995,1008],"using":[36,746],"pentaspline":[38,567],"catheter":[39,307,520,568,579],"for":[40,90,101,124,136,195,230,573,674,705,718,763,770,813,859,885],"pulmonary":[41,217],"vein":[42,218],"isolation":[43],"(PVI)":[44],"and":[45,54,69,80,145,151,163,220,227,374,412,439,513,522,600,606,625,766,879,906,964,976,982,989,996,998,1010,1040,1061],"additional":[46,344,542,555,759],"posterior":[47],"wall":[48],"(65%),":[49],"as":[50,52,73,111,539,541,693,707,709,827,829,902,942,1006],"well":[51,540,635,708,828],"cavotricuspid":[53],"mitral":[55,598],"isthmus":[56,599],"ablation.":[57],"They":[58],"found":[59,177,320],"strong":[61],"correlation":[62],"between":[63,371,620],"amount":[65,547,627,665],"applications":[68,332,373,427,470,556],"evidence":[70,793],"hemolysis":[72,109,295,325,378,477,491,509,624,662,667,706,740,941,997],"determined":[74],"by":[75,518,562,944,1058],"fHb,":[76],"lacate":[77],"dehydrogenase":[78],"(LDH),":[79],"billirubin.":[81],"Based":[82],"on":[83,161,449,678,818,844,1043],"these":[84,358,454,515,637,915],"data,":[85,263],"they":[86,301,319,784,852],"created":[87,668],"threshold":[89,655],"induction":[91],"major":[93,661],"This":[95,1018],"in":[96,121,146,149,181,252,296,340,379,390,453,478,588,695,741,755,801,954],"turn":[97,147],"could":[98,919],"imply":[99],"risk":[100,483,702,938],"occurrence":[103,376,622,659,738],"significant":[105,952],"clinical":[106,420,461,672,711],"complications":[107,212,712],"such":[110,213],"renal":[112,285,980],"failure.":[113],"is":[115,156,205,422,570,604,611,650,686,791,799,810,968,972,1035,1041,1055],"an":[116,700,715],"emerging":[117],"non-thermal":[118],"energy":[119],"source":[120],"cardiac":[122,127,877,958],"electrophysiology":[123],"tissue.":[128],"Here,":[129],"intermittent,":[130],"high-intensity":[131],"electrical":[132],"fields":[133],"are":[134,512,516,726],"applied":[135,432],"extremely":[137],"short":[138],"periods":[139],"time":[141],"(micro-":[142],"or":[143,158,559],"nanoseconds),":[144],"result":[148],"cellular":[150],"tissue":[152,180,878,962],"pore":[153],"formation":[154],"that":[155,206,406,428,440,486,534,569,586,796,918,934,971,1021],"reversible":[157],"irreversible":[159],"(depending":[160],"settings":[162],"properties),":[166],"ultimately":[167],"leading":[168],"cell":[170],"death":[171],"[2,":[172],"3].":[173],"has":[175,191,247,386,580,631,669,837,866],"been":[176,248,633,781,838,867],"destroy":[179],"more":[183,338],"selective":[184],"way":[185],"than":[186],"established":[187],"thermal":[188],"modalities,":[189],"which":[190,402,609],"fueled":[192],"hope":[194,204],"development":[196,698],"truly":[199],"cardiomyocyte-selective":[200],"approach.":[202],"The":[203,361,418,1063],"would":[208],"subsequently":[209],"eliminate":[210],"devastating":[211],"as,":[214],"atrial-esophageal":[215],"fistula,":[216],"stenosis,":[219],"phrenic":[221,907],"nerve":[222,908],"palsy.":[223],"Most":[224],"recent":[225],"study":[226,299],"registry":[228],"data":[229,258,271,356,362,528,638,735],"appears":[232,442,533],"quite":[233],"promising":[234],"regarding":[235,736],"outcomes,":[236],"but":[237,783,851],"particularly":[238,1005],"safety":[240,257,276],"[4,":[243],"5].":[244],"As":[245],"it":[246,499,532,685,911],"proven":[249],"many":[250,468,776],"times":[251],"past,":[254],"real":[255],"world":[256],"oftentimes":[259,687],"challenges":[260,754],"our":[261,696,756],"initial":[262],"deriving":[264],"from":[265,272,363,608,640,1046],"limited":[266,643,788],"amounts":[267],"patients.":[269,646],"Recent":[270],"largest":[274],"registry,":[277],"discovered":[278],"relatively":[280,381,582,634],"unexpected":[281],"complication":[282,900,970],"hemolysis-related":[284],"failure":[286,981],"[4].":[287],"Osmancik":[288],"[6]":[291],"characterized":[293],"PFA-related":[294],"focused":[298],"where":[300],"compared":[302,346],"who":[304,342,536],"underwent":[305,343],"radiofrequency":[306],"(RFA)":[309],"PFA.":[311],"total":[314],"number":[315,329,425,441,494,644],"70":[317],"dose-related":[322],"effect":[323],"markers":[326],"[6].":[333],"turn,":[335],"effects":[336],"were":[337],"pronounced":[339],"PVI":[348,538,762,779,836],"only.":[349],"Several":[350],"other":[351,601,841,860,1007],"groups":[352],"have":[353,780,786,1065],"provided":[354,529],"similar":[355],"supporting":[357],"findings":[359],"[7].":[360],"confirms":[368],"association":[370,993],"linear":[382,451,574,602],"relationship.":[383],"However,":[384],"one":[385,931],"be":[388,431,444,464,472,501,614,714,728,854,921,1015],"careful":[389],"interpreting":[391],"proposed":[393,864],"\u201coptimal":[394,419],"cut-off\u201d":[395,421],"74":[397],"applications,":[398],"statistical":[400],"term,":[401],"means":[403],"value":[405],"gives":[407,487],"equal":[408],"weight":[409],"sensitivity":[411],"specificity":[413,963],"while":[414,1029],"maximizing":[415],"prediction":[416,703],"accuracy.":[417],"maximum":[424],"can":[429,471],"safely":[430],"without":[433,474],"incurring":[434,475],"any":[435,476],"hemolytic":[436],"adverse":[437,1001],"event":[438],"somewhere":[445],"around":[446],"66":[447],"based":[448,817,843],"relationship":[452],"data.":[455],"A":[456],"useful":[457],"contribution":[458,717],"literature":[462],"will":[463,500,713,1012,1019],"know":[466],"how":[467,514],"done":[473,922],"form":[480],"stratification":[484],"table":[485],"probability":[489],"applications.":[497],"Mechanistically,":[498],"important":[502,716],"understand":[504,991],"what":[505],"determinants":[507],"impacted":[517],"design":[521,564],"ablation/PFA":[524],"settings.":[525],"so":[530],"far,":[531],"undergo":[537],"lines":[543],"develop":[544],"larger":[546],"Is":[550],"simply":[552],"due":[553,924],"even":[560,792],"enhanced":[561],"not":[571,920],"optimized":[572],"ablation?":[575],"For":[576,773],"example,":[577],"large":[583],"surface":[584],"area":[585,883],"gets":[587],"contact":[589],"blood":[592],"volume":[593],"when":[594,663],"locations":[603],"performed":[605],"poles":[607],"delivered":[612],"cannot":[613],"turned":[615],"off.":[616],"While":[617,684],"dose-relationship":[619],"used":[630],"now":[632],"described,":[636],"derive":[639],"very":[642,670],"How":[647],"clinically":[648,1016],"meaningful":[649],"determination":[652],"avoid":[657],"different":[671,845],"implications":[673],"each":[675],"patient":[676,1031],"depending":[677],"e.g.":[679],"baseline":[681],"kidney":[682],"function.":[683],"difficult":[688],"go":[690],"beyond":[691,761,778,835],"surrogates":[692],"endpoints":[694],"field,":[697],"accurate":[701],"model":[704],"its":[710],"future.":[720],"Nevertheless,":[721],"congratulated":[729],"provide":[731],"us":[732],"undergoing":[743],"AF":[744,765,775,850],"Pentaspline":[748],"catheter.":[749],"Some":[750],"longstanding":[753],"includes":[758],"persistent":[764,774],"making":[767,856,910],"deeper":[768],"lesions":[769],"ventricular":[771],"arrhythmias.":[772],"strategies":[777,816,861],"proposed,":[782],"all":[785],"had":[787],"success.":[789],"There":[790],"suggest":[795],"repeat":[797],"helpful":[800],"preserving":[802],"mechanical":[805],"function":[806],"[8].":[807],"Hence,":[808],"there":[809],"need":[812],"developing":[814],"newer":[815],"combination":[820],"mechanism":[823],"underlying":[824],"arrhythmia":[826],"optimizing":[830],"strategies.":[832],"One":[833,863],"strategy":[834],"target":[840],"areas":[842],"metrics":[846],"like":[847,927],"drivers":[848],"might":[853],"ephemeral":[855],"case":[858],"[9].":[862],"approach":[865],"make":[869],"use":[870],"refractory":[873],"period":[874],"minimize":[880],"contiguous":[882],"available":[884],"fibrillatory":[886],"waves":[887],"sustain":[889],"themselves":[890],"[10,":[891],"11].":[892],"provides":[894],"distinct":[895],"advantages":[896],"given":[897],"better":[899],"profile":[901],"regards":[903],"esophageal":[905,928],"injury":[909],"possible":[912],"pursue":[914],"approaches":[917],"earlier":[923],"concerns":[926],"injury.":[929,984],"Nonetheless,":[930],"must":[932],"balance":[933],"optimism":[935],"dose-dependent":[940],"outlined":[943],"[1].":[948],"represents":[950],"advancement":[953],"treatment":[956],"arrhythmias,":[959],"including":[960],"increased":[961],"reduced":[965],"complications.":[966],"Hemolysis":[967],"unique":[973],"potentially":[977],"leads":[978],"liver":[983],"Ongoing":[985],"research":[986,1044],"determine":[988],"fully":[990],"prevention":[999],"outcomes":[1002],"remains":[1003],"essential,":[1004],"catheters":[1009],"systems":[1011],"start":[1013],"used.":[1017],"ensure":[1020],"we":[1022],"harness":[1023],"benefits":[1025],"technology":[1028],"safeguarding":[1030],"health.":[1032],"Ravi":[1033],"Ranjan":[1034],"consultant":[1037],"Abbott":[1039],"PI":[1042],"grants":[1045],"Biosense":[1047],"Webster":[1048],"University":[1051],"Utah.":[1053],"He":[1054],"also":[1056],"supported":[1057],"NIH":[1059],"R01HL142913":[1060],"R01HL162353.":[1062],"authors":[1064],"nothing":[1066],"report.":[1068]},"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2024-11-19T00:00:00"}