{"id":"https://openalex.org/W4404258945","doi":"https://doi.org/10.1016/j.ijscr.2024.110600","title":"A long-term recurrence-free case of colorectal cancer with 13 simultaneous liver metastases: A case report","display_name":"A long-term recurrence-free case of colorectal cancer with 13 simultaneous liver metastases: A case report","publication_year":2024,"publication_date":"2024-11-12","ids":{"openalex":"https://openalex.org/W4404258945","doi":"https://doi.org/10.1016/j.ijscr.2024.110600","pmid":"https://pubmed.ncbi.nlm.nih.gov/39547031","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11607655"},"language":"en","primary_location":{"id":"doi:10.1016/j.ijscr.2024.110600","doi":"https://doi.org/10.1016/j.ijscr.2024.110600","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijscr.2024.110600","pdf_url":null,"source":{"id":"https://openalex.org/S5398819","display_name":"International Journal of Surgery Case Reports","issn_l":"2210-2612","issn":["2210-2612"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Surgery Case Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.ijscr.2024.110600","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102905528","display_name":"Masataka Nakagawa","orcid":"https://orcid.org/0009-0000-8727-3017","observed_orcids":["https://orcid.org/0009-0000-8727-3017"]},"institutions":[{"id":"https://openalex.org/I4405252996","display_name":"Medical Corporation JR Hiroshima Hospital","ror":"https://ror.org/006tv5x42","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405252996"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masataka Nakagawa","raw_affiliation_strings":["Department of Surgery, JR Hiroshima Hospital, 3-1-36 Hutabanosato, Higashi-ku, Hiroshima 732-0057, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, JR Hiroshima Hospital, 3-1-36 Hutabanosato, Higashi-ku, Hiroshima 732-0057, Japan","institution_ids":["https://openalex.org/I4405252996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014702892","display_name":"Daisuke Sumitani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405252996","display_name":"Medical Corporation JR Hiroshima Hospital","ror":"https://ror.org/006tv5x42","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405252996"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Daisuke Sumitani","raw_affiliation_strings":["Department of Surgery, JR Hiroshima Hospital, 3-1-36 Hutabanosato, Higashi-ku, Hiroshima 732-0057, Japan. Electronic address: sudaisuke@yahoo.co.jp"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, JR Hiroshima Hospital, 3-1-36 Hutabanosato, Higashi-ku, Hiroshima 732-0057, Japan. Electronic address: sudaisuke@yahoo.co.jp","institution_ids":["https://openalex.org/I4405252996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049886641","display_name":"Keiso Matsubara","orcid":"https://orcid.org/0000-0001-6346-0475","observed_orcids":["https://orcid.org/0000-0001-6346-0475"]},"institutions":[{"id":"https://openalex.org/I4405252996","display_name":"Medical Corporation JR Hiroshima Hospital","ror":"https://ror.org/006tv5x42","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405252996"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Keiso Matsubara","raw_affiliation_strings":["Department of Surgery, JR Hiroshima Hospital, 3-1-36 Hutabanosato, Higashi-ku, Hiroshima 732-0057, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, JR Hiroshima Hospital, 3-1-36 Hutabanosato, Higashi-ku, Hiroshima 732-0057, Japan","institution_ids":["https://openalex.org/I4405252996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108389459","display_name":"Hiroshi Ota","orcid":"https://orcid.org/0000-0002-2771-2337","observed_orcids":["https://orcid.org/0000-0002-2771-2337","https://orcid.org/0009-0002-2839-2563"]},"institutions":[{"id":"https://openalex.org/I4405252996","display_name":"Medical Corporation JR Hiroshima Hospital","ror":"https://ror.org/006tv5x42","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405252996"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroshi Ota","raw_affiliation_strings":["Department of Surgery, JR Hiroshima Hospital, 3-1-36 Hutabanosato, Higashi-ku, Hiroshima 732-0057, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, JR Hiroshima Hospital, 3-1-36 Hutabanosato, Higashi-ku, Hiroshima 732-0057, Japan","institution_ids":["https://openalex.org/I4405252996"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103808526","display_name":"Masatsugu Yano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405252996","display_name":"Medical Corporation JR Hiroshima Hospital","ror":"https://ror.org/006tv5x42","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405252996"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masatsugu Yano","raw_affiliation_strings":["Department of Surgery, JR Hiroshima Hospital, 3-1-36 Hutabanosato, Higashi-ku, Hiroshima 732-0057, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, JR Hiroshima Hospital, 3-1-36 Hutabanosato, Higashi-ku, Hiroshima 732-0057, Japan","institution_ids":["https://openalex.org/I4405252996"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5014702892"],"corresponding_institution_ids":["https://openalex.org/I4405252996"],"apc_list":{"value":1800,"currency":"USD","value_usd":1800},"apc_paid":{"value":1800,"currency":"USD","value_usd":1800},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"125","issue":"C","first_page":"110600","last_page":"110600"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":0.9106000065803528,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":0.9106000065803528,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.07590000331401825,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/colorectal-liver-metastases","display_name":"colorectal liver metastases","score":0.8989999890327454},{"id":"https://openalex.org/keywords/multiple-liver-metastases","display_name":"multiple liver metastases","score":0.8080000281333923},{"id":"https://openalex.org/keywords/eob-mri","display_name":"EOB-MRI","score":0.5979999899864197},{"id":"https://openalex.org/keywords/partial-hepatectomy","display_name":"partial hepatectomy","score":0.8199999928474426},{"id":"https://openalex.org/keywords/conversion-surgery","display_name":"conversion surgery","score":0.5889999866485596},{"id":"https://openalex.org/keywords/laparoscopic-colectomy","display_name":"laparoscopic colectomy","score":0.7279999852180481},{"id":"https://openalex.org/keywords/mfolfox6","display_name":"mFOLFOX6","score":0.9070000052452087},{"id":"https://openalex.org/keywords/panitumumab","display_name":"panitumumab","score":0.9980000257492065},{"id":"https://openalex.org/keywords/capecitabine","display_name":"capecitabine","score":0.9599999785423279},{"id":"https://openalex.org/keywords/oxaliplatin","display_name":"oxaliplatin","score":0.9729999899864197},{"id":"https://openalex.org/keywords/recurrence-free-survival","display_name":"recurrence-free survival","score":0.699999988079071},{"id":"https://openalex.org/keywords/residual-disease","display_name":"residual disease","score":0.43700000643730164}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.946509599685669},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.7861801981925964},{"id":"https://openalex.org/C61797465","wikidata":"https://www.wikidata.org/wiki/Q1188986","display_name":"Term (time)","level":2,"score":0.5931953191757202},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.49469825625419617},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46167421340942383},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.42783066630363464},{"id":"https://openalex.org/C61434518","wikidata":"https://www.wikidata.org/wiki/Q932510","display_name":"General surgery","level":1,"score":0.35227513313293457},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1016/j.ijscr.2024.110600","doi":"https://doi.org/10.1016/j.ijscr.2024.110600","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijscr.2024.110600","pdf_url":null,"source":{"id":"https://openalex.org/S5398819","display_name":"International Journal of Surgery Case Reports","issn_l":"2210-2612","issn":["2210-2612"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Surgery Case Reports","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11607655","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11607655","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11607655/pdf/main.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Surg Case Rep","raw_type":"Text"},{"id":"pmid:39547031","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39547031","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of surgery case reports","raw_type":"Case Reports"}],"best_oa_location":{"id":"doi:10.1016/j.ijscr.2024.110600","doi":"https://doi.org/10.1016/j.ijscr.2024.110600","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijscr.2024.110600","pdf_url":null,"source":{"id":"https://openalex.org/S5398819","display_name":"International Journal of Surgery Case Reports","issn_l":"2210-2612","issn":["2210-2612"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Surgery Case Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4404258945.pdf","grobid_xml":"https://content.openalex.org/works/W4404258945.grobid-xml"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W1988711912","https://openalex.org/W2054265070","https://openalex.org/W2057156320","https://openalex.org/W2066040529","https://openalex.org/W2081193693","https://openalex.org/W2104804192","https://openalex.org/W2155854000","https://openalex.org/W2302003756","https://openalex.org/W2402513422","https://openalex.org/W2597799908","https://openalex.org/W2750892969","https://openalex.org/W2783686102","https://openalex.org/W2793100661","https://openalex.org/W3138659588","https://openalex.org/W4229002154","https://openalex.org/W4291672004","https://openalex.org/W4362521115"],"related_works":["https://openalex.org/W2793100661","https://openalex.org/W4407389997","https://openalex.org/W4388848750","https://openalex.org/W2990743418","https://openalex.org/W4413817322","https://openalex.org/W7129103443","https://openalex.org/W2038909825","https://openalex.org/W2990191071","https://openalex.org/W4363676630","https://openalex.org/W2895403725"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Metastatic":[1],"liver":[2,19,26,37,67,260],"tumors":[3],"result":[4],"from":[5,29],"distant":[6],"metastasis":[7,90],"of":[8,17,69,95,111,185,214,219,226,250,290],"a":[9,75,195],"primary":[10,97,292,306],"tumor.":[11,293],"While":[12],"chemotherapy":[13,112,187,283],"is":[14,21,202,240,253,266,272],"the":[15,96,132,164,172,180,217,256,291,305],"treatment":[16,49],"choice,":[18],"resection":[20,102,137,249,289,299],"aggressively":[22],"performed":[23],"for":[24],"metastatic":[25],"cancer":[27,71],"derived":[28],"colorectal":[30,70],"cancer.":[31],"However,":[32,157],"during":[33],"chemotherapy,":[34],"some":[35],"disappearing":[36],"metastases":[38,68],"(DLMs)":[39],"can":[40,262],"be":[41,243,263],"undetectable":[42],"on":[43,125,238],"computed":[44],"tomography":[45],"(CT),":[46],"and":[47,61,80,120,138,141,151,167,175,190,205,229,268,284,300],"surgical":[48,298],"remains":[50],"challenging.":[51],"PRESENTATION":[52],"OF":[53],"CASE:":[54],"A":[55],"48-year-old":[56],"woman":[57],"with":[58,65,113,188,278],"abdominal":[59],"pain":[60],"constipation":[62],"was":[63,106,149],"diagnosed":[64,235],"multiple":[66,279],"(CRLM)":[72],"origin":[73],"after":[74],"thorough":[76],"examination":[77],"involving":[78],"CT":[79,239],"ethoxybenzyl-magnetic":[81],"resonance":[82],"imaging.":[83],"Thirteen":[84],"simultaneous":[85],"CRLM":[86,119,162],"were":[87,123,155],"observed":[88],"(largest":[89],"diameter,":[91],"37":[92],"mm).":[93],"Resection":[94],"tumor":[98,169],"(laparoscopy-assisted":[99],"left":[100],"colon":[101],"+":[103,115],"D3":[104],"dissection)":[105],"performed.":[107],"Following":[108],"eight":[109,183],"courses":[110,184],"mFOLFOX6":[114],"panitumumab,":[116],"only":[117],"two":[118],"11":[121],"DLMs":[122,220,237,252],"detectable":[124,153],"CT.":[126],"With":[127],"no":[128,168],"new":[129],"lesions":[130,154],"identified,":[131],"patient":[133,181,201],"underwent":[134,285],"anterior":[135,165],"segment":[136,139,142,166,173,176],"3":[140,174],"7":[143,177],"partial":[144],"hepatectomies.":[145],"Contrast-enhanced":[146],"intraoperative":[147],"ultrasonography":[148],"performed,":[150],"all":[152],"resected.":[156],"pathology":[158],"results":[159],"showed":[160],"three":[161],"in":[163,171,216],"cells":[170],"specimens.":[178],"Postoperatively,":[179],"received":[182],"adjuvant":[186],"capecitabine":[189,193],"oxaliplatin":[191],"(with":[192],"as":[194,236],"single":[196],"agent":[197],"beginning":[198],"mid-course).":[199],"The":[200,212,224],"currently":[203],"alive":[204],"recurrence-free":[206],"3.5":[207],"years":[208],"post-hepatic":[209],"resection.":[210],"DISCUSSION:":[211],"utility":[213],"EOB-MRI":[215],"detection":[218],"has":[221],"been":[222],"demonstrated.":[223],"incidence":[225],"residual":[227,259],"disease":[228],"subsequent":[230],"early":[231],"recurrence":[232,265],"at":[233],"sites":[234],"reported":[241],"to":[242,255,282],"approximately":[244],"80":[245],"%.":[246],"Although":[247],"aggressive":[248],"resectable":[251],"desirable":[254],"extent":[257],"that":[258],"function":[261],"preserved,":[264],"frequent":[267],"long-term":[269],"careful":[270],"follow-up":[271],"considered":[273],"important.":[274],"CONCLUSION:":[275],"Our":[276],"patient,":[277],"CRLM,":[280],"responded":[281],"conversion":[286],"surgery":[287],"following":[288],"Surgeons":[294],"should":[295],"consider":[296],"possible":[297],"DLM":[301],"management":[302],"when":[303],"selecting":[304],"treatment.":[307]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-11-12T00:00:00"}