{"id":"https://openalex.org/W4404100613","doi":"https://doi.org/10.1183/13993003.congress-2024.pa1692","title":"Difficult decannulation: impact of an individualized strategy on the survival of patients with neuromuscular diseases.","display_name":"Difficult decannulation: impact of an individualized strategy on the survival of patients with neuromuscular diseases.","publication_year":2024,"publication_date":"2024-09-14","ids":{"openalex":"https://openalex.org/W4404100613","doi":"https://doi.org/10.1183/13993003.congress-2024.pa1692"},"language":"en","primary_location":{"id":"doi:10.1183/13993003.congress-2024.pa1692","doi":"https://doi.org/10.1183/13993003.congress-2024.pa1692","is_oa":false,"landing_page_url":"https://doi.org/10.1183/13993003.congress-2024.pa1692","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Noninvasive ventilatory support","raw_type":"proceedings-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042105665","display_name":"Deborah Dos Reis Estrella","orcid":"https://orcid.org/0000-0001-5182-9749","observed_orcids":["https://orcid.org/0000-0001-5182-9749"]},"institutions":[{"id":"https://openalex.org/I110200422","display_name":"Universidade Federal de Minas Gerais","ror":"https://ror.org/0176yjw32","country_code":"BR","type":"education","lineage":["https://openalex.org/I110200422"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Deborah Dos Reis Estrella","raw_affiliation_strings":["1Federal University of Minas Gerais, Belo Horizonte, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Federal University of Minas Gerais, Belo Horizonte, Brazil","institution_ids":["https://openalex.org/I110200422"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5095944802","display_name":"Renata Meira Isensee","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Renata Meira Isensee","raw_affiliation_strings":["2J\u00falia Kubitschek Hospital, Belo Horizonte, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2J\u00falia Kubitschek Hospital, Belo Horizonte, Brazil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5095944801","display_name":"Brigida Amatto","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brigida Amatto","raw_affiliation_strings":["2J\u00falia Kubitschek Hospital, Belo Horizonte, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2J\u00falia Kubitschek Hospital, Belo Horizonte, Brazil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032117853","display_name":"Felipe Santos da Silva","orcid":"https://orcid.org/0000-0002-1409-4832","observed_orcids":["https://orcid.org/0000-0002-1409-4832"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Felipe Silva","raw_affiliation_strings":["2J\u00falia Kubitschek Hospital, Belo Horizonte, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2J\u00falia Kubitschek Hospital, Belo Horizonte, Brazil","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Sabrina Bernardes","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sabrina Bernardes","raw_affiliation_strings":["2J\u00falia Kubitschek Hospital, Belo Horizonte, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2J\u00falia Kubitschek Hospital, Belo Horizonte, Brazil","institution_ids":[]}]},{"author_position":"last","author":{"id":null,"display_name":"Mauro Vidigal De Rezende Lopes","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mauro Vidigal De Rezende Lopes","raw_affiliation_strings":["2J\u00falia Kubitschek Hospital, Belo Horizonte, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2J\u00falia Kubitschek Hospital, Belo Horizonte, Brazil","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"PA1692","last_page":"PA1692"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.8593999743461609,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.8593999743461609,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11260","display_name":"Tracheal and airway disorders","score":0.05550000071525574,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10830","display_name":"Airway Management and Intubation Techniques","score":0.01979999989271164,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuromuscular-disorders","display_name":"neuromuscular disorders","score":0.9940000176429749},{"id":"https://openalex.org/keywords/weaning-from-mechanical-ventilation","display_name":"weaning from mechanical ventilation","score":0.7850000262260437},{"id":"https://openalex.org/keywords/tracheostomy","display_name":"tracheostomy","score":0.8209999799728394},{"id":"https://openalex.org/keywords/amyotrophic-lateral-sclerosis","display_name":"amyotrophic lateral sclerosis","score":0.8489999771118164},{"id":"https://openalex.org/keywords/duchenne-muscular-dystrophy","display_name":"Duchenne muscular dystrophy","score":1.0},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.8370000123977661},{"id":"https://openalex.org/keywords/shared-decision-making","display_name":"shared decision-making","score":0.7099999785423279},{"id":"https://openalex.org/keywords/respiratory-failure","display_name":"respiratory failure","score":0.5170000195503235}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4704441428184509},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.39256376028060913},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.377599835395813},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3511250615119934}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1183/13993003.congress-2024.pa1692","doi":"https://doi.org/10.1183/13993003.congress-2024.pa1692","is_oa":false,"landing_page_url":"https://doi.org/10.1183/13993003.congress-2024.pa1692","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Noninvasive ventilatory support","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/5","score":0.4300000071525574,"display_name":"Gender equality"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W3031052312","https://openalex.org/W4389568370","https://openalex.org/W3032375762","https://openalex.org/W1995515455","https://openalex.org/W2080531066","https://openalex.org/W3108674512","https://openalex.org/W1506200166"],"abstract_inverted_index":{"Background:":[0],"Patients":[1,120],"with":[2,7,53,96,210],"neuromuscular":[3,140],"diseases":[4,141],"(NMDs)":[5],"faced":[6],"respiratory":[8],"failure,":[9],"infectious":[10],"processes":[11],"and":[12,19,40,104,137,151,158,189,204,223],"severe":[13],"bulbar":[14],"impairment":[15],"are":[16],"frequently":[17],"intubated":[18],"tracheostomized":[20],"in":[21,69,74,101,173,201,231],"Intensive":[22],"Care":[23],"Units":[24],"worldwide.":[25],"For":[26],"this":[27],"patient":[28],"profile,":[29],"there":[30],"is":[31],"no":[32],"defined":[33],"proposal":[34],"regarding":[35],"weaning":[36],"from":[37,64],"mechanical":[38],"ventilation":[39,94],"decannulation":[41,85,175],"outside":[42],"the":[43,48,97,105,174,218,224],"Reference":[44,72],"Centres.":[45],"Objective:":[46],"Evaluate":[47],"10-year":[49],"survival":[50,165],"of":[51],"patients":[52,63,80,170,188,209],"NMD":[54,71,84],"who":[55,171,228],"tolerate":[56],"decannulation.":[57],"Methodology:":[58],"Retrospective":[59],"study":[60],"that":[61],"included":[62],"11/2013":[65],"to":[66,112,127,207],"10/2023":[67],"managed":[68],"an":[70,82,202],"Center":[73],"Belo":[75],"Horizonte/Brazil.":[76],"The":[77,163],"33":[78],"decannulated":[79],"followed":[81],"individualized":[83,203],"protocol,":[86],"which":[87],"was":[88,110,177],"carried":[89],"out":[90],"based":[91],"on":[92],"non-invasive":[93],"trials":[95],"tracheostomy":[98,213],"tube":[99],"still":[100],"place,":[102],"capped":[103],"cuff":[106],"deflated.":[107],"Inspiratory":[108],"pressure":[109],"titrated":[111],"optimize":[113],"SaO2":[114],"\u2265":[115],"94%":[116],"without":[117],"supplemental":[118],"oxygen.":[119],"were":[121,153],"divided":[122],"into":[123],"three":[124],"groups":[125],"according":[126],"diagnosis:":[128],"Amyotrophic":[129],"lateral":[130],"sclerosis":[131],"(ALS),":[132],"Duchenne":[133],"Muscular":[134],"Dystrophy":[135],"(DMD),":[136],"other":[138],"uncommon":[139],"(other":[142],"NMDs).":[143],"Survival":[144],"estimates":[145],"for":[146,169,181,186,192,217],"each":[147],"group":[148],"(ALS,":[149],"DMD":[150,187],"Other-NDMs)":[152],"expressed":[154],"by":[155,167],"Kaplan-Meier":[156],"curves":[157],"compared":[159],"using":[160],"Log-Rank.":[161],"Results:":[162],"median":[164],"assessed":[166],"diagnosis":[168],"succeed":[172],"process":[176],"approximately":[178],"52":[179],"months":[180,185,191],"ALS":[182],"patients,":[183],"64":[184],"38":[190],"Other":[193],"NMDs.":[194,211],"Conclusion:":[195],"All":[196],"efforts":[197],"must":[198],"be":[199,215],"undertaken":[200],"safe":[205],"protocol":[206],"decannulate":[208],"A":[212],"should":[214],"considered":[216],"patient,":[219],"their":[220],"family":[221],"members":[222],"health":[225],"professionals":[226],"team":[227],"assist":[229],"them":[230],"a":[232],"shared":[233],"decision.":[234]},"counts_by_year":[],"updated_date":"2026-09-23T05:00:35.095934","created_date":"2025-10-10T00:00:00"}