{"id":"https://openalex.org/W4403971290","doi":"https://doi.org/10.1016/j.ymben.2024.11.001","title":"Generation of a Vibrio-based platform for efficient conversion of raffinose through Adaptive Laboratory Evolution on a solid medium","display_name":"Generation of a Vibrio-based platform for efficient conversion of raffinose through Adaptive Laboratory Evolution on a solid medium","publication_year":2024,"publication_date":"2024-11-01","ids":{"openalex":"https://openalex.org/W4403971290","doi":"https://doi.org/10.1016/j.ymben.2024.11.001","pmid":"https://pubmed.ncbi.nlm.nih.gov/39489215"},"language":"en","primary_location":{"id":"doi:10.1016/j.ymben.2024.11.001","doi":"https://doi.org/10.1016/j.ymben.2024.11.001","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ymben.2024.11.001","pdf_url":null,"source":{"id":"https://openalex.org/S173328182","display_name":"Metabolic Engineering","issn_l":"1096-7176","issn":["1096-7176","1096-7184"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolic Engineering","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059418899","display_name":"Sunghwa Woo","orcid":"https://orcid.org/0000-0002-1500-8107","observed_orcids":["https://orcid.org/0000-0002-1500-8107"]},"institutions":[{"id":"https://openalex.org/I123900574","display_name":"Pohang University of Science and Technology","ror":"https://ror.org/04xysgw12","country_code":"KR","type":"education","lineage":["https://openalex.org/I123900574"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sunghwa Woo","raw_affiliation_strings":["Department of Chemical Engineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, South Korea","institution_ids":["https://openalex.org/I123900574"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083853234","display_name":"Yong Hee Han","orcid":"https://orcid.org/0000-0002-2963-6921","observed_orcids":["https://orcid.org/0000-0002-2963-6921"]},"institutions":[{"id":"https://openalex.org/I111277659","display_name":"Chonnam National University","ror":"https://ror.org/05kzjxq56","country_code":"KR","type":"education","lineage":["https://openalex.org/I111277659"]},{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yong Hee Han","raw_affiliation_strings":["Interdisciplinary Program in Bioengineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea; School of Biological Sciences and Technology, Chonnam National University, Yongbong-ro 77, Gwangju, 61186, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Interdisciplinary Program in Bioengineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea; School of Biological Sciences and Technology, Chonnam National University, Yongbong-ro 77, Gwangju, 61186, South Korea","institution_ids":["https://openalex.org/I111277659","https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100615728","display_name":"Hye Kyung Lee","orcid":"https://orcid.org/0009-0004-5442-7605","observed_orcids":["https://orcid.org/0009-0004-5442-7605"]},"institutions":[{"id":"https://openalex.org/I123900574","display_name":"Pohang University of Science and Technology","ror":"https://ror.org/04xysgw12","country_code":"KR","type":"education","lineage":["https://openalex.org/I123900574"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Hye Kyung Lee","raw_affiliation_strings":["Division of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, South Korea","institution_ids":["https://openalex.org/I123900574"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005684758","display_name":"Dongyeop Baek","orcid":"https://orcid.org/0000-0001-8582-2502","observed_orcids":["https://orcid.org/0000-0001-8582-2502"]},"institutions":[{"id":"https://openalex.org/I123900574","display_name":"Pohang University of Science and Technology","ror":"https://ror.org/04xysgw12","country_code":"KR","type":"education","lineage":["https://openalex.org/I123900574"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Dongyeop Baek","raw_affiliation_strings":["Department of Chemical Engineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, South Korea","institution_ids":["https://openalex.org/I123900574"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000328867","display_name":"Myung Hyun Noh","orcid":"https://orcid.org/0000-0001-9045-7968","observed_orcids":["https://orcid.org/0000-0001-9045-7968"]},"institutions":[{"id":"https://openalex.org/I4210151417","display_name":"Korea Research Institute of Chemical Technology","ror":"https://ror.org/043k4kk20","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210151417"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Myung Hyun Noh","raw_affiliation_strings":["Center for Bio-based Chemistry, Korea Research Institute of Chemical Technology (KRICT), 406-30, Jonggaro, Junggu, Ulsan, 44429, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Bio-based Chemistry, Korea Research Institute of Chemical Technology (KRICT), 406-30, Jonggaro, Junggu, Ulsan, 44429, South Korea","institution_ids":["https://openalex.org/I4210151417"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Sukjae Han","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sukjae Han","raw_affiliation_strings":["Interdisciplinary Program in Bioengineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Interdisciplinary Program in Bioengineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014839787","display_name":"Hyun Gyu Lim","orcid":"https://orcid.org/0000-0002-0469-2388","observed_orcids":["https://orcid.org/0000-0002-0469-2388"]},"institutions":[{"id":"https://openalex.org/I191879574","display_name":"Inha University","ror":"https://ror.org/01easw929","country_code":"KR","type":"education","lineage":["https://openalex.org/I191879574"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Hyun Gyu Lim","raw_affiliation_strings":["Department of Biological Sciences and Bioengineering, Inha University, Inha-ro 100, Michuhol-gu, Incheon, 22212, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences and Bioengineering, Inha University, Inha-ro 100, Michuhol-gu, Incheon, 22212, South Korea","institution_ids":["https://openalex.org/I191879574"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079269717","display_name":"Gyoo Yeol Jung","orcid":"https://orcid.org/0000-0002-9742-3207","observed_orcids":["https://orcid.org/0000-0002-9742-3207"]},"institutions":[{"id":"https://openalex.org/I123900574","display_name":"Pohang University of Science and Technology","ror":"https://ror.org/04xysgw12","country_code":"KR","type":"education","lineage":["https://openalex.org/I123900574"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Gyoo Yeol Jung","raw_affiliation_strings":["Department of Chemical Engineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, South Korea; Division of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, South Korea. Electronic address: gyjung@postech.ac.kr"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, South Korea; Division of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, South Korea. Electronic address: gyjung@postech.ac.kr","institution_ids":["https://openalex.org/I123900574"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066692256","display_name":"Sang Woo Seo","orcid":"https://orcid.org/0000-0002-7434-7053","observed_orcids":["https://orcid.org/0000-0002-7434-7053"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Sang Woo Seo","raw_affiliation_strings":["Interdisciplinary Program in Bioengineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea; School of Chemical and Biological Engineering, South Korea; Institute of Chemical Processes, South Korea; Bio-MAX Institute, South Korea; Institute of Bio Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea. Electronic address: swseo@snu.ac.kr"],"raw_orcid":"https://orcid.org/0000-0002-7434-7053","affiliations":[{"raw_affiliation_string":"Interdisciplinary Program in Bioengineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea; School of Chemical and Biological Engineering, South Korea; Institute of Chemical Processes, South Korea; Bio-MAX Institute, South Korea; Institute of Bio Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea. Electronic address: swseo@snu.ac.kr","institution_ids":["https://openalex.org/I139264467"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5066692256","https://openalex.org/A5079269717"],"corresponding_institution_ids":["https://openalex.org/I123900574","https://openalex.org/I139264467"],"apc_list":{"value":4870,"currency":"USD","value_usd":4870},"apc_paid":null,"fwci":0.7784,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.64049804,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"86","issue":null,"first_page":"300","last_page":"307"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10171","display_name":"Biofuel production and bioconversion","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14150","display_name":"Biochemical and biochemical processes","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vibrio","display_name":"Vibrio","score":0.8989999890327454},{"id":"https://openalex.org/keywords/adaptive-laboratory-evolution","display_name":"adaptive laboratory evolution","score":0.9959999918937683},{"id":"https://openalex.org/keywords/alternative-carbon-sources","display_name":"alternative carbon sources","score":0.7609999775886536},{"id":"https://openalex.org/keywords/raffinose-hydrolysis","display_name":"raffinose hydrolysis","score":0.7099999785423279},{"id":"https://openalex.org/keywords/galactose-catabolism","display_name":"galactose catabolism","score":0.7559999823570251},{"id":"https://openalex.org/keywords/missense-mutations","display_name":"missense mutations","score":0.5370000004768372}],"concepts":[{"id":"https://openalex.org/C2779998883","wikidata":"https://www.wikidata.org/wiki/Q410005","display_name":"Raffinose","level":3,"score":0.7145450115203857},{"id":"https://openalex.org/C2776154503","wikidata":"https://www.wikidata.org/wiki/Q753490","display_name":"Vibrio","level":3,"score":0.4410548210144043},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40562209486961365},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.38201242685317993},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.34648409485816956},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.2597053647041321},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.22544294595718384},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10004076361656189},{"id":"https://openalex.org/C2778597767","wikidata":"https://www.wikidata.org/wiki/Q4027534","display_name":"Sucrose","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003470","descriptor_name":"Culture Media","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011887","descriptor_name":"Raffinose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014733","descriptor_name":"Vibrio","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014733","descriptor_name":"Vibrio","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019020","descriptor_name":"Directed Molecular Evolution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060847","descriptor_name":"Metabolic Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.ymben.2024.11.001","doi":"https://doi.org/10.1016/j.ymben.2024.11.001","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ymben.2024.11.001","pdf_url":null,"source":{"id":"https://openalex.org/S173328182","display_name":"Metabolic Engineering","issn_l":"1096-7176","issn":["1096-7176","1096-7184"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolic Engineering","raw_type":"journal-article"},{"id":"pmid:39489215","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39489215","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolic engineering","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":67,"referenced_works":["https://openalex.org/W1677337874","https://openalex.org/W1709815505","https://openalex.org/W1967600116","https://openalex.org/W1990556407","https://openalex.org/W1994342039","https://openalex.org/W2006339296","https://openalex.org/W2010018128","https://openalex.org/W2020366340","https://openalex.org/W2035779669","https://openalex.org/W2036163270","https://openalex.org/W2047360542","https://openalex.org/W2049564364","https://openalex.org/W2077088772","https://openalex.org/W2086561953","https://openalex.org/W2087063661","https://openalex.org/W2096381604","https://openalex.org/W2105018820","https://openalex.org/W2107277218","https://openalex.org/W2111634327","https://openalex.org/W2115941371","https://openalex.org/W2132238954","https://openalex.org/W2140952049","https://openalex.org/W2141401164","https://openalex.org/W2142284828","https://openalex.org/W2142678478","https://openalex.org/W2155861738","https://openalex.org/W2156527767","https://openalex.org/W2290768068","https://openalex.org/W2336342668","https://openalex.org/W2609024085","https://openalex.org/W2612254264","https://openalex.org/W2751396518","https://openalex.org/W2753885635","https://openalex.org/W2794889462","https://openalex.org/W2889233581","https://openalex.org/W2945551031","https://openalex.org/W2948788437","https://openalex.org/W2949212020","https://openalex.org/W2967876620","https://openalex.org/W2991231507","https://openalex.org/W3010388894","https://openalex.org/W3011093590","https://openalex.org/W3024270344","https://openalex.org/W3110669441","https://openalex.org/W3136140199","https://openalex.org/W3137168643","https://openalex.org/W3140567931","https://openalex.org/W3164446886","https://openalex.org/W3179042872","https://openalex.org/W3185454444","https://openalex.org/W3203343200","https://openalex.org/W3209499641","https://openalex.org/W3213261241","https://openalex.org/W4205192056","https://openalex.org/W4229370427","https://openalex.org/W4254711046","https://openalex.org/W4281491402","https://openalex.org/W4298326738","https://openalex.org/W4313360712","https://openalex.org/W4318705079","https://openalex.org/W4362737740","https://openalex.org/W4379522965","https://openalex.org/W4382930123","https://openalex.org/W4386515327","https://openalex.org/W4389525119","https://openalex.org/W4390701164","https://openalex.org/W4390943107"],"related_works":["https://openalex.org/W7165666360","https://openalex.org/W7053354564","https://openalex.org/W2155861738","https://openalex.org/W4409413491","https://openalex.org/W4285803174","https://openalex.org/W4292117580","https://openalex.org/W7098033123","https://openalex.org/W2954764446","https://openalex.org/W2517647412","https://openalex.org/W2084553888"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-11-02T00:00:00"}