{"id":"https://openalex.org/W4403898677","doi":"https://doi.org/10.1016/j.placenta.2024.10.020","title":"Feto-placental vascular structure and in silico haemodynamics: Of mice, rats, and human","display_name":"Feto-placental vascular structure and in silico haemodynamics: Of mice, rats, and human","publication_year":2024,"publication_date":"2024-10-30","ids":{"openalex":"https://openalex.org/W4403898677","doi":"https://doi.org/10.1016/j.placenta.2024.10.020","pmid":"https://pubmed.ncbi.nlm.nih.gov/39476476"},"language":"en","primary_location":{"id":"doi:10.1016/j.placenta.2024.10.020","doi":"https://doi.org/10.1016/j.placenta.2024.10.020","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.placenta.2024.10.020","pdf_url":null,"source":{"id":"https://openalex.org/S171513543","display_name":"Placenta","issn_l":"0143-4004","issn":["0143-4004","1532-3102"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Placenta","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W4403898677"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.placenta.2024.10.020","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000528067","display_name":"Nikhilesh Bappoo","orcid":"https://orcid.org/0000-0002-1500-2741","observed_orcids":["https://orcid.org/0000-0002-1500-2741"]},"institutions":[{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]},{"id":"https://openalex.org/I2799971621","display_name":"Harry Perkins Institute of Medical Research","ror":"https://ror.org/02xz7d723","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2799971621"]},{"id":"https://openalex.org/I4210088912","display_name":"Queen Elizabeth II Medical Centre","ror":"https://ror.org/0071a2k97","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210088912"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Nikhilesh Bappoo","raw_affiliation_strings":["Vascular Engineering Laboratory, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Perth, Australia; School of Engineering, The University of Western Australia, Perth, Australia; School of Human Sciences, The University of Western Australia, Perth, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vascular Engineering Laboratory, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Perth, Australia; School of Engineering, The University of Western Australia, Perth, Australia; School of Human Sciences, The University of Western Australia, Perth, Australia","institution_ids":["https://openalex.org/I177877127","https://openalex.org/I2799971621","https://openalex.org/I4210088912"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045515637","display_name":"Yutthapong Tongpob","orcid":"https://orcid.org/0000-0002-5228-5111","observed_orcids":["https://orcid.org/0000-0002-5228-5111"]},"institutions":[{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]},{"id":"https://openalex.org/I66200439","display_name":"Naresuan University","ror":"https://ror.org/03e2qe334","country_code":"TH","type":"education","lineage":["https://openalex.org/I66200439"]}],"countries":["AU","TH"],"is_corresponding":false,"raw_author_name":"Yutthapong Tongpob","raw_affiliation_strings":["School of Human Sciences, The University of Western Australia, Perth, Australia; Centre of Excellence in Medical Biotechnology, Faculty of Medical Science, Naresuan University, Phitsanulok, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Human Sciences, The University of Western Australia, Perth, Australia; Centre of Excellence in Medical Biotechnology, Faculty of Medical Science, Naresuan University, Phitsanulok, Thailand","institution_ids":["https://openalex.org/I177877127","https://openalex.org/I66200439"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Matina Hakim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Matina Hakim","raw_affiliation_strings":["Maternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, University of Manchester, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Maternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064959070","display_name":"Jenny Myers","orcid":"https://orcid.org/0000-0003-0913-2096","observed_orcids":["https://orcid.org/0000-0003-0913-2096"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jenny Myers","raw_affiliation_strings":["Maternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, University of Manchester, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Maternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043230996","display_name":"Emma Panting","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Emma Panting","raw_affiliation_strings":["School of Human Sciences, The University of Western Australia, Perth, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Human Sciences, The University of Western Australia, Perth, Australia","institution_ids":["https://openalex.org/I177877127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084052287","display_name":"Karen E. Chapman","orcid":"https://orcid.org/0000-0001-7777-6817","observed_orcids":["https://orcid.org/0000-0001-7777-6817"]},"institutions":[{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]},{"id":"https://openalex.org/I4210164624","display_name":"The Queen's Medical Research Institute","ror":"https://ror.org/059zxg644","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210164624","https://openalex.org/I98677209"]},{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["AU","GB"],"is_corresponding":false,"raw_author_name":"Karen E. Chapman","raw_affiliation_strings":["School of Human Sciences, The University of Western Australia, Perth, Australia; Centre for Cardiovascular Science, The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, EH16 4TJ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Human Sciences, The University of Western Australia, Perth, Australia; Centre for Cardiovascular Science, The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, EH16 4TJ, UK","institution_ids":["https://openalex.org/I177877127","https://openalex.org/I4210164624","https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065112664","display_name":"Adrian J. W. Thomson","orcid":"https://orcid.org/0000-0001-7320-300X","observed_orcids":["https://orcid.org/0000-0001-7320-300X"]},"institutions":[{"id":"https://openalex.org/I4210164624","display_name":"The Queen's Medical Research Institute","ror":"https://ror.org/059zxg644","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210164624","https://openalex.org/I98677209"]},{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Adrian J.W. Thomson","raw_affiliation_strings":["Centre for Cardiovascular Science, The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, EH16 4TJ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Cardiovascular Science, The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, EH16 4TJ, UK","institution_ids":["https://openalex.org/I4210164624","https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028036727","display_name":"Carmel Mary MORAN","orcid":"https://orcid.org/0000-0002-2105-2948","observed_orcids":["https://orcid.org/0000-0002-2105-2948"]},"institutions":[{"id":"https://openalex.org/I4210164624","display_name":"The Queen's Medical Research Institute","ror":"https://ror.org/059zxg644","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210164624","https://openalex.org/I98677209"]},{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Carmel M. Moran","raw_affiliation_strings":["Centre for Cardiovascular Science, The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, EH16 4TJ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Cardiovascular Science, The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, EH16 4TJ, UK","institution_ids":["https://openalex.org/I4210164624","https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076298947","display_name":"Lachlan J. Kelsey","orcid":"https://orcid.org/0000-0003-3175-4051","observed_orcids":["https://orcid.org/0000-0003-3175-4051"]},"institutions":[{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]},{"id":"https://openalex.org/I2799971621","display_name":"Harry Perkins Institute of Medical Research","ror":"https://ror.org/02xz7d723","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2799971621"]},{"id":"https://openalex.org/I4210088912","display_name":"Queen Elizabeth II Medical Centre","ror":"https://ror.org/0071a2k97","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210088912"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Lachlan J. Kelsey","raw_affiliation_strings":["Vascular Engineering Laboratory, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Perth, Australia; School of Engineering, The University of Western Australia, Perth, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vascular Engineering Laboratory, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Perth, Australia; School of Engineering, The University of Western Australia, Perth, Australia","institution_ids":["https://openalex.org/I177877127","https://openalex.org/I2799971621","https://openalex.org/I4210088912"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056502880","display_name":"Vijayalakshmi Srinivasan","orcid":"https://orcid.org/0000-0001-6958-3855","observed_orcids":["https://orcid.org/0000-0001-6958-3855"]},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Vijayalakshmi Srinivasan","raw_affiliation_strings":["Auckland Bioengineering Institute, University of Auckland, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Auckland Bioengineering Institute, University of Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013538627","display_name":"Joanna L. James","orcid":"https://orcid.org/0000-0002-3757-4177","observed_orcids":["https://orcid.org/0000-0002-3757-4177"]},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Joanna L. James","raw_affiliation_strings":["Department of Obstetrics and Gynaecology, Faculty of Medical and Health Sciences, University of Auckland, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynaecology, Faculty of Medical and Health Sciences, University of Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021269128","display_name":"Alys Rachel Clark","orcid":"https://orcid.org/0000-0001-5908-2862","observed_orcids":["https://orcid.org/0000-0001-5908-2862"]},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Alys R. Clark","raw_affiliation_strings":["Auckland Bioengineering Institute, University of Auckland, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Auckland Bioengineering Institute, University of Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031893743","display_name":"Barry J. Doyle","orcid":"https://orcid.org/0000-0003-4923-2796","observed_orcids":["https://orcid.org/0000-0003-4923-2796"]},"institutions":[{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]},{"id":"https://openalex.org/I2799971621","display_name":"Harry Perkins Institute of Medical Research","ror":"https://ror.org/02xz7d723","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2799971621"]},{"id":"https://openalex.org/I4210088912","display_name":"Queen Elizabeth II Medical Centre","ror":"https://ror.org/0071a2k97","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210088912"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Barry J. Doyle","raw_affiliation_strings":["Vascular Engineering Laboratory, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Perth, Australia; School of Engineering, The University of Western Australia, Perth, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vascular Engineering Laboratory, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Perth, Australia; School of Engineering, The University of Western Australia, Perth, Australia","institution_ids":["https://openalex.org/I177877127","https://openalex.org/I2799971621","https://openalex.org/I4210088912"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070293758","display_name":"Caitlin S. Wyrwoll","orcid":"https://orcid.org/0000-0002-5746-5680","observed_orcids":["https://orcid.org/0000-0002-5746-5680"]},"institutions":[{"id":"https://openalex.org/I175234967","display_name":"The Kids Research Institute Australia","ror":"https://ror.org/01dbmzx78","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I175234967"]},{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Caitlin S. Wyrwoll","raw_affiliation_strings":["School of Human Sciences, The University of Western Australia, Perth, Australia; Telethon Kids Institute, Perth, Australia. Electronic address: caitlin.wyrwoll@uwa.edu.au"],"raw_orcid":"https://orcid.org/0000-0002-5746-5680","affiliations":[{"raw_affiliation_string":"School of Human Sciences, The University of Western Australia, Perth, Australia; Telethon Kids Institute, Perth, Australia. Electronic address: caitlin.wyrwoll@uwa.edu.au","institution_ids":["https://openalex.org/I175234967","https://openalex.org/I177877127"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5070293758"],"corresponding_institution_ids":["https://openalex.org/I175234967","https://openalex.org/I177877127"],"apc_list":{"value":3610,"currency":"USD","value_usd":3610},"apc_paid":{"value":3610,"currency":"USD","value_usd":3610},"fwci":5.732,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.9633007,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"158","issue":null,"first_page":"175","last_page":"184"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mouse-placenta","display_name":"mouse placenta","score":0.5910000205039978},{"id":"https://openalex.org/keywords/rat-placenta","display_name":"rat placenta","score":1.0},{"id":"https://openalex.org/keywords/human-placenta","display_name":"human placenta","score":0.949999988079071},{"id":"https://openalex.org/keywords/cotyledons","display_name":"cotyledons","score":0.6710000038146973},{"id":"https://openalex.org/keywords/vascularity","display_name":"vascularity","score":0.7229999899864197},{"id":"https://openalex.org/keywords/cross-species-comparison","display_name":"cross-species comparison","score":0.7179999947547913},{"id":"https://openalex.org/keywords/preclinical-animal-models","display_name":"preclinical animal models","score":0.6600000262260437},{"id":"https://openalex.org/keywords/fetal-development","display_name":"fetal development","score":0.5640000104904175},{"id":"https://openalex.org/keywords/computational-fluid-dynamics","display_name":"computational fluid dynamics","score":0.6669999957084656}],"concepts":[{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.8293357491493225},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.5372109413146973},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3715493977069855},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3307238221168518},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3096376061439514},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.27249181270599365},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10087800025939941},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07799506187438965}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010920","descriptor_name":"Placenta","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":true},{"descriptor_ui":"D010920","descriptor_name":"Placenta","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021041","descriptor_name":"Placental Circulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055114","descriptor_name":"X-Ray Microtomography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1016/j.placenta.2024.10.020","doi":"https://doi.org/10.1016/j.placenta.2024.10.020","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.placenta.2024.10.020","pdf_url":null,"source":{"id":"https://openalex.org/S171513543","display_name":"Placenta","issn_l":"0143-4004","issn":["0143-4004","1532-3102"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Placenta","raw_type":"journal-article"},{"id":"pmid:39476476","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39476476","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Placenta","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:openaire/877c1b45-f5e7-4467-acae-44341b2433d9","doi":null,"is_oa":true,"landing_page_url":"https://research-repository.uwa.edu.au/en/publications/877c1b45-f5e7-4467-acae-44341b2433d9","pdf_url":null,"source":{"id":"https://openalex.org/S4306402492","display_name":"UWA Profiles and Research Repository (UWA)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177877127","host_organization_name":"The University of Western Australia","host_organization_lineage":["https://openalex.org/I177877127"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bappoo, N, Tongpob, Y, Hakim, M, Myers, J, Panting, E, Chapman, K E, Thomson, A J W, Moran, C M, Kelsey, L J, Srinivasan, V, James, J L, Clark, A R, Doyle, B J & Wyrwoll, C S 2024, 'Feto-placental vascular structure and in silico haemodynamics : Of mice, rats, and human', Placenta, vol. 158, pp. 175-184. https://doi.org/10.1016/j.placenta.2024.10.020","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/4609973f-75ff-493c-9c2f-64746d567f85","doi":null,"is_oa":true,"landing_page_url":"https://research.manchester.ac.uk/en/publications/4609973f-75ff-493c-9c2f-64746d567f85","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bappoo, N, Tongpob, Y, Hakim, M, Myers, J, Panting, E, Chapman, K E, Thomson, A J W, Moran, C M, Kelsey, L J, Srinivasan, V, James, J L, Clark, A R, Doyle, B & Wyrwoll, C S 2024, 'Feto-placental vascular structure and in silico haemodynamics: Of mice, rats, and human', Placenta, vol. 158, pp. 175-184. https://doi.org/10.1016/j.placenta.2024.10.020","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.ed.ac.uk:openaire/45962f5d-e5d6-4b32-bb59-07d5582af998","doi":null,"is_oa":true,"landing_page_url":"https://www.research.ed.ac.uk/en/publications/45962f5d-e5d6-4b32-bb59-07d5582af998","pdf_url":null,"source":{"id":"https://openalex.org/S4306400321","display_name":"Edinburgh Research Explorer (University of Edinburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I98677209","host_organization_name":"University of Edinburgh","host_organization_lineage":["https://openalex.org/I98677209"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bappoo, N, Tongpob, Y, Hakim, M, Myers, J, Panting, E, Chapman, K E, Thomson, A J W, Moran, C M, Kelsey, L J, Srinivasan, V, James, J L, Clark, A R, Doyle, B & Wyrwoll, C S 2024, 'Feto-placental vascular structure and in silico haemodynamics: of mice, rats, and human', Placenta, vol. 158, pp. 175-184. https://doi.org/10.1016/j.placenta.2024.10.020","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.placenta.2024.10.020","doi":"https://doi.org/10.1016/j.placenta.2024.10.020","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.placenta.2024.10.020","pdf_url":null,"source":{"id":"https://openalex.org/S171513543","display_name":"Placenta","issn_l":"0143-4004","issn":["0143-4004","1532-3102"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Placenta","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320315885","display_name":"Australian Government","ror":"https://ror.org/0314h5y94"},{"id":"https://openalex.org/F4320320023","display_name":"Tommy's Baby Charity","ror":"https://ror.org/04rre2k21"},{"id":"https://openalex.org/F4320320473","display_name":"Raine Medical Research Foundation","ror":"https://ror.org/04agdqh30"},{"id":"https://openalex.org/F4320320774","display_name":"Royal Society Te Ap\u0101rangi","ror":"https://ror.org/04tajb587"},{"id":"https://openalex.org/F4320323612","display_name":"Department of Health, Government of Western Australia","ror":"https://ror.org/01epcny94"},{"id":"https://openalex.org/F4320325703","display_name":"Tommy's","ror":null},{"id":"https://openalex.org/F4320326768","display_name":"Government of Western Australia","ror":"https://ror.org/00wqdbc63"},{"id":"https://openalex.org/F5037574137","display_name":"Department of Health, Government of Western Australia","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1970508192","https://openalex.org/W1977071831","https://openalex.org/W1984241541","https://openalex.org/W1988321289","https://openalex.org/W1989043392","https://openalex.org/W1994865551","https://openalex.org/W2030613990","https://openalex.org/W2056807152","https://openalex.org/W2062700681","https://openalex.org/W2098209538","https://openalex.org/W2130807679","https://openalex.org/W2152460775","https://openalex.org/W2161158639","https://openalex.org/W2308595026","https://openalex.org/W2397417653","https://openalex.org/W2592385138","https://openalex.org/W2799500525","https://openalex.org/W2886094490","https://openalex.org/W2888745236","https://openalex.org/W2956414682","https://openalex.org/W2958183105","https://openalex.org/W3083518835","https://openalex.org/W3118765718","https://openalex.org/W3123759929","https://openalex.org/W3125103697","https://openalex.org/W3130174200","https://openalex.org/W3134526910","https://openalex.org/W3196027299"],"related_works":["https://openalex.org/W7056480525","https://openalex.org/W3196027299","https://openalex.org/W2973142130","https://openalex.org/W2967762232","https://openalex.org/W4386594172","https://openalex.org/W4386057124","https://openalex.org/W2970846294","https://openalex.org/W2750404716","https://openalex.org/W2517040393","https://openalex.org/W2004021642"],"abstract_inverted_index":{"INTRODUCTION:":[0],"The":[1],"complex":[2],"arborization":[3,199],"of":[4,61,197],"the":[5,26,49,59,150,195,208],"feto-placental":[6,53,90,123,198],"vasculature":[7,91],"is":[8,45],"crucial":[9,39],"for":[10,69],"optimal":[11],"fetal":[12,204],"nutrition,":[13],"waste":[14],"exchange":[15,182],"and":[16,20,36,51,84,93,98,110,116,125,139,145,190,203],"ultimately,":[17],"development.":[18],"Ethical":[19],"experimental":[21,30],"limitations":[22],"constrain":[23],"research":[24,187],"into":[25],"human":[27,130,209],"placenta,":[28,112],"hence":[29],"animal":[31],"models":[32],"such":[33,172],"as":[34,153,173],"mice":[35],"rats,":[37,97],"are":[38,114,164],"to":[40,88,121,143,178,193],"understand":[41,194],"placental":[42,70,180,186,201],"function.":[43,126,183],"It":[44],"unclear":[46],"how":[47],"well":[48],"mouse":[50,111,191],"rat":[52,109,189],"vascular":[54,64],"structure":[55,92,124],"emulates":[56],"human.":[57,99],"Moreover,":[58],"implications":[60],"differences":[62,107],"in":[63,67,95,149],"structure,":[65],"especially":[66],"arborization,":[68],"function":[71,202],"remain":[72],"unclear.":[73],"METHODS:":[74],"We":[75,127],"use":[76],"micro-computed":[77],"tomography":[78],"imaging,":[79],"high":[80],"frequency":[81],"Doppler":[82],"ultrasound":[83],"computational":[85],"fluid":[86],"dynamics":[87],"characterize":[89],"haemodynamics":[94,113],"mice,":[96],"RESULTS:":[100],"Our":[101],"data":[102],"suggest":[103],"that":[104,117,129,169],"despite":[105],"structural":[106],"between":[108],"similar":[115,142],"both":[118],"hold":[119],"applicability":[120],"investigating":[122],"show":[128,157],"cotyledons":[131],"demonstrate":[132,168],"vascularity-dependent":[133],"haemodynamic":[134],"behaviour":[135],"(including":[136],"flow":[137],"deceleration":[138],"oxygen":[140,181],"exchange)":[141],"rodents":[144],"can":[146,175,206],"be":[147,176],"analysed":[148],"same":[151],"spectrum":[152],"rodents.":[154],"Finally,":[155],"we":[156,167],"strong":[158],"structure-function":[159],"relationships":[160],"when":[161],"interspecies":[162],"datasets":[163],"combined;":[165],"notably,":[166],"surrogate":[170],"measures":[171],"vascularity,":[174],"used":[177],"estimate":[179],"DISCUSSION:":[184],"Pre-clinical":[185],"utilising":[188],"placentae":[192],"impact":[196],"on":[200],"development":[205],"inform":[207],"context.":[210]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":5}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2024-10-31T00:00:00"}
