{"id":"https://openalex.org/W4403725543","doi":"https://doi.org/10.14309/01.ajg.0001042840.17623.49","title":"S3368 Black Esophagus\u2014A Rare Cause of Upper GI Bleeding in the Metastatic Pancreatic Cancer after Initiation of FOLFIRINOX Chemotherapy","display_name":"S3368 Black Esophagus\u2014A Rare Cause of Upper GI Bleeding in the Metastatic Pancreatic Cancer after Initiation of FOLFIRINOX Chemotherapy","publication_year":2024,"publication_date":"2024-10-01","ids":{"openalex":"https://openalex.org/W4403725543","doi":"https://doi.org/10.14309/01.ajg.0001042840.17623.49"},"language":"en","primary_location":{"id":"doi:10.14309/01.ajg.0001042840.17623.49","doi":"https://doi.org/10.14309/01.ajg.0001042840.17623.49","is_oa":false,"landing_page_url":"https://doi.org/10.14309/01.ajg.0001042840.17623.49","pdf_url":null,"source":{"id":"https://openalex.org/S66441642","display_name":"The American Journal of Gastroenterology","issn_l":"0002-9270","issn":["0002-9270","1572-0241"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101851135","display_name":"Rida Fatima","orcid":"https://orcid.org/0000-0002-2088-1381","observed_orcids":["https://orcid.org/0000-0002-2088-1381"]},"institutions":[{"id":"https://openalex.org/I4210156573","display_name":"Bassett Medical Center","ror":"https://ror.org/05fk0de79","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210155413","https://openalex.org/I4210156573"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Rida Fatima","raw_affiliation_strings":["Bassett Medical Center, Cooperstown, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bassett Medical Center, Cooperstown, NY;","institution_ids":["https://openalex.org/I4210156573"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100439310","display_name":"Muhammad Bilal","orcid":"https://orcid.org/0000-0001-5388-3183","observed_orcids":["https://orcid.org/0000-0001-5388-3183","https://orcid.org/0009-0003-0272-0474","https://orcid.org/0000-0003-4221-0877","https://orcid.org/0000-0001-8221-2389","https://orcid.org/0000-0002-3807-0034","https://orcid.org/0000-0003-1035-9925","https://orcid.org/0009-0001-5853-0835","https://orcid.org/0009-0002-7917-3037","https://orcid.org/0009-0003-7850-3134"]},"institutions":[{"id":"https://openalex.org/I4210156573","display_name":"Bassett Medical Center","ror":"https://ror.org/05fk0de79","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210155413","https://openalex.org/I4210156573"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Muhammad Bilal","raw_affiliation_strings":["Bassett Medical Center, Cooperstown, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bassett Medical Center, Cooperstown, NY;","institution_ids":["https://openalex.org/I4210156573"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Azhar Hussain","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I20388574","display_name":"SUNY Upstate Medical University","ror":"https://ror.org/040kfrw16","country_code":"US","type":"education","lineage":["https://openalex.org/I20388574"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Azhar Hussain","raw_affiliation_strings":["SUNY Upstate Medical University, Syracuse, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SUNY Upstate Medical University, Syracuse, NY;","institution_ids":["https://openalex.org/I20388574"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104185263","display_name":"Saurav Kini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1290900354","display_name":"Tufts Medical Center","ror":"https://ror.org/002hsbm82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1290900354"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Saurav Kini","raw_affiliation_strings":["Tufts Medical Center, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tufts Medical Center, Boston, MA","institution_ids":["https://openalex.org/I1290900354"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065970662","display_name":"Peter S. Francisco","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210156573","display_name":"Bassett Medical Center","ror":"https://ror.org/05fk0de79","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210155413","https://openalex.org/I4210156573"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter Francisco","raw_affiliation_strings":["Bassett Medical Center, Cooperstown, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bassett Medical Center, Cooperstown, NY;","institution_ids":["https://openalex.org/I4210156573"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5101851135"],"corresponding_institution_ids":["https://openalex.org/I4210156573"],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"119","issue":"10S","first_page":"S2249","last_page":"S2250"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11378","display_name":"Gastrointestinal Bleeding Diagnosis and Treatment","score":0.3440000116825104,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11378","display_name":"Gastrointestinal Bleeding Diagnosis and Treatment","score":0.3440000116825104,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11658","display_name":"Esophageal and GI Pathology","score":0.3285999894142151,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":0.07460000365972519,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/black-esophagus","display_name":"black esophagus","score":0.9909999966621399},{"id":"https://openalex.org/keywords/folfirinox","display_name":"FOLFIRINOX","score":0.8190000057220459},{"id":"https://openalex.org/keywords/metastatic-pancreatic-cancer","display_name":"metastatic pancreatic cancer","score":0.9369999766349792},{"id":"https://openalex.org/keywords/upper-gastrointestinal-bleeding","display_name":"upper gastrointestinal bleeding","score":0.9070000052452087},{"id":"https://openalex.org/keywords/esophageal-mucosal-necrosis","display_name":"esophageal mucosal necrosis","score":0.7889999747276306},{"id":"https://openalex.org/keywords/chemotherapy-side-effects","display_name":"chemotherapy side effects","score":0.6489999890327454},{"id":"https://openalex.org/keywords/proton-pump-inhibitors","display_name":"proton pump inhibitors","score":0.6840000152587891},{"id":"https://openalex.org/keywords/pantoprazole","display_name":"pantoprazole","score":0.8029999732971191},{"id":"https://openalex.org/keywords/octreotide","display_name":"octreotide","score":0.765999972820282},{"id":"https://openalex.org/keywords/esophageal-perforation","display_name":"esophageal perforation","score":0.8299999833106995},{"id":"https://openalex.org/keywords/esophageal-stricture","display_name":"esophageal stricture","score":0.8669999837875366},{"id":"https://openalex.org/keywords/hematemesis","display_name":"hematemesis","score":0.6299999952316284},{"id":"https://openalex.org/keywords/melena","display_name":"melena","score":0.9599999785423279},{"id":"https://openalex.org/keywords/elderly-patients","display_name":"elderly patients","score":0.6769999861717224},{"id":"https://openalex.org/keywords/conservative-treatment","display_name":"conservative treatment","score":0.6330000162124634},{"id":"https://openalex.org/keywords/upper-endoscopy","display_name":"upper gastrointestinal endoscopy","score":0.8569999933242798}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9765661954879761},{"id":"https://openalex.org/C2777148230","wikidata":"https://www.wikidata.org/wiki/Q17144959","display_name":"FOLFIRINOX","level":5,"score":0.8908078074455261},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.6943637728691101},{"id":"https://openalex.org/C2777819096","wikidata":"https://www.wikidata.org/wiki/Q173710","display_name":"Esophagus","level":2,"score":0.6579371094703674},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5852985978126526},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46408602595329285},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4331514239311218},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.37238550186157227},{"id":"https://openalex.org/C2780962732","wikidata":"https://www.wikidata.org/wiki/Q422327","display_name":"Oxaliplatin","level":4,"score":0.17875686287879944},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.14309/01.ajg.0001042840.17623.49","doi":"https://doi.org/10.14309/01.ajg.0001042840.17623.49","is_oa":false,"landing_page_url":"https://doi.org/10.14309/01.ajg.0001042840.17623.49","pdf_url":null,"source":{"id":"https://openalex.org/S66441642","display_name":"The American Journal of Gastroenterology","issn_l":"0002-9270","issn":["0002-9270","1572-0241"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Gastroenterology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3208879731","https://openalex.org/W2912805378","https://openalex.org/W2773811619","https://openalex.org/W3150959662","https://openalex.org/W2279265429","https://openalex.org/W2326775466","https://openalex.org/W2998882136","https://openalex.org/W2913605867","https://openalex.org/W3000648514","https://openalex.org/W2044767323"],"abstract_inverted_index":{"Introduction:":[0],"Black":[1,341],"esophagus,":[2,248,312],"a":[3,56,68,82,173,256,275],"rare":[4],"clinical":[5],"condition":[6],"with":[7,81,105,128,137,212,231,282,344],"an":[8,141,161],"unclear":[9],"incidence":[10],"or":[11],"prevalence,":[12],"is":[13,270,279,301],"characterized":[14],"by":[15],"the":[16,22,46,103,111,122,168,178,183,190,199,219,238,311,320,326],"diffuse":[17],"circumferential":[18],"black":[19,59,174,247,267,369],"appearance":[20],"of":[21,48,58,63,201,292,310,322,348,363],"esophageal":[23,49,52,323],"mucosa.":[24],"It":[25],"typically":[26],"presents":[27],"as":[28],"upper":[29],"gastrointestinal":[30],"bleeding.":[31],"Risk":[32],"factors":[33],"include":[34,45],"hypertension,":[35,88],"coronary":[36],"artery":[37],"disease,":[38],"diabetes":[39,91],"mellitus,":[40,92],"and":[41,51,93,107,160,192,216,228,260,296,325,346,365],"underlying":[42],"malignancy.":[43],"Complications":[44],"formation":[47],"strictures":[50],"perforation.":[53],"We":[54],"present":[55],"case":[57,258],"esophagus":[60,175,180,268,364],"after":[61],"initiation":[62,291],"FOLFIRINOX":[64],"in":[65,144,234,254,304],"pancreatic":[66,97,145,202],"cancer,":[67],"potential":[69],"association":[70],"that":[71],"has":[72,251],"not":[73],"been":[74,252],"widely":[75],"reported.":[76],"Case":[77],"Description/Methods:":[78],"81-year-old":[79],"female":[80],"past":[83],"medical":[84],"history":[85],"significant":[86],"for":[87],"type":[89],"2":[90],"recently":[94],"diagnosed":[95],"metastatic":[96],"cancer":[98,203],"on":[99,153,226,266],"chemotherapy":[100],"presented":[101],"to":[102,182,319],"hospital":[104,220],"hematemesis":[106],"melena.":[108],"On":[109,120],"presentation,":[110,121],"patient":[112,150,208,223,239,327],"was":[113,118,125,131,151,166,205,224],"vitally":[114],"stable.":[115],"Physical":[116],"examination":[117],"unremarkable.":[119,206],"patient's":[123],"hemoglobin":[124,130,217],"8.0":[126],"g/dl,":[127],"baseline":[129],"around":[132],"10":[133],"g/dl.":[134],"CT":[135],"Abdomen":[136],"IV":[138,154],"contrast":[139],"showed":[140,172],"interval":[142],"increase":[143],"head":[146],"mass":[147],"size.":[148],"The":[149,207,222],"started":[152],"pantoprazole":[155,227],"40":[156],"mg":[157],"twice":[158],"daily":[159],"octreotide":[162],"infusion.":[163],"Esophagogastroduodenoscopy":[164],"(EGD)":[165],"done":[167,197,303,317],"next":[169],"day,":[170],"which":[171],"appreciated":[176],"from":[177],"proximal":[179],"down":[181],"gastroesophageal":[184,366],"junction":[185,367],"without":[186],"any":[187],"active":[188],"bleeding;":[189],"stomach":[191],"duodenum":[193],"appeared":[194],"normal.":[195],"EGD":[196,233,300,314],"at":[198],"time":[200],"diagnosis":[204],"tolerated":[209],"oral":[210],"intake":[211],"stable":[213],"hemodynamic":[214],"status":[215],"over":[218],"course.":[221],"discharged":[225],"sucralfate":[229],"suspension":[230],"follow-up":[232],"1-2":[235,305],"months.":[236,306],"Unfortunately,":[237],"died":[240],"before":[241],"her":[242],"repeat":[243],"EGD.":[244,298],"Discussion:":[245],"Post-Chemotherapy":[246],"including":[249],"FOLFIRINOX,":[250],"reported":[253],"only":[255],"few":[257],"reports":[259],"series1.":[261],"Although":[262],"no":[263],"proper":[264],"data":[265],"mortality":[269],"available,":[271],"it":[272],"usually":[273,302],"indicates":[274],"poor":[276],"prognosis.":[277],"Treatment":[278],"generally":[280],"conservative":[281],"fluid":[283],"resuscitation/blood":[284],"transfusion":[285],"if":[286],"needed,":[287],"avoiding":[288],"hypotension,":[289],"early":[290],"proton":[293],"pump":[294],"inhibitors,":[295],"timely":[297],"Follow-up":[299],"In":[307],"transmural":[308],"necrosis":[309],"diligent":[313],"should":[315,328],"be":[316,329],"due":[318],"risk":[321],"perforation":[324],"carefully":[330],"monitored":[331],"(see":[332],"Figure":[333],"1).":[334],"Reference":[335],"1":[336],"Forys":[337],"OC,":[338],"Ferguson":[339],"DD.":[340],"Esophagus":[342],"Associated":[343],"Malignancy":[345],"Use":[347],"FOLFOX/Avastin.":[349],"Am":[350],"J":[351],"Gastroenterol.":[352],"2007":[353],"Sep;102(Suppl):S125.Figure":[354],"1.:":[355],"A,":[356],"B,":[357],"C":[358],"showing":[359,368],"Upper,":[360],"middle":[361],"third":[362],"esophagus.":[370],"D)":[371],"normal":[372],"gastric":[373],"body.":[374]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-22T18:32:59.640997","created_date":"2024-10-25T00:00:00"}
