{"id":"https://openalex.org/W4403722990","doi":"https://doi.org/10.14309/01.ajg.0001044616.56420.d0","title":"S3812 Nowhere to Heyde: An Unusual Case of Acquired Coagulopathy-Induced Gastrointestinal Bleeding","display_name":"S3812 Nowhere to Heyde: An Unusual Case of Acquired Coagulopathy-Induced Gastrointestinal Bleeding","publication_year":2024,"publication_date":"2024-10-01","ids":{"openalex":"https://openalex.org/W4403722990","doi":"https://doi.org/10.14309/01.ajg.0001044616.56420.d0"},"language":"en","primary_location":{"id":"doi:10.14309/01.ajg.0001044616.56420.d0","doi":"https://doi.org/10.14309/01.ajg.0001044616.56420.d0","is_oa":false,"landing_page_url":"https://doi.org/10.14309/01.ajg.0001044616.56420.d0","pdf_url":null,"source":{"id":"https://openalex.org/S66441642","display_name":"The American Journal of Gastroenterology","issn_l":"0002-9270","issn":["0002-9270","1572-0241"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042338665","display_name":"Rahil Desai","orcid":"https://orcid.org/0000-0003-0605-3309","observed_orcids":["https://orcid.org/0000-0003-0605-3309"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Rahil Desai","raw_affiliation_strings":["Presenter"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Presenter","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010623109","display_name":"Shil Punatar","orcid":"https://orcid.org/0000-0001-9189-9784","observed_orcids":["https://orcid.org/0000-0001-9189-9784"]},"institutions":[{"id":"https://openalex.org/I2799894082","display_name":"Franciscan Health","ror":"https://ror.org/01hbes477","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799894082"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shil Punatar","raw_affiliation_strings":["Franciscan Health Olympia Fields, Chicago, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Franciscan Health Olympia Fields, Chicago, IL","institution_ids":["https://openalex.org/I2799894082"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114392136","display_name":"Nabiha Haider","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799894082","display_name":"Franciscan Health","ror":"https://ror.org/01hbes477","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799894082"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nabiha Haider","raw_affiliation_strings":["Franciscan Health Olympia Fields, Chicago, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Franciscan Health Olympia Fields, Chicago, IL","institution_ids":["https://openalex.org/I2799894082"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108871661","display_name":"Shyamal Sheth","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799894082","display_name":"Franciscan Health","ror":"https://ror.org/01hbes477","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799894082"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shyamal Sheth","raw_affiliation_strings":["Franciscan Health Olympia Fields, Chicago, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Franciscan Health Olympia Fields, Chicago, IL","institution_ids":["https://openalex.org/I2799894082"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114392137","display_name":"Vishak Vinod","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799894082","display_name":"Franciscan Health","ror":"https://ror.org/01hbes477","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799894082"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vishak Vinod","raw_affiliation_strings":["Franciscan Health Olympia Fields, Chicago, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Franciscan Health Olympia Fields, Chicago, IL","institution_ids":["https://openalex.org/I2799894082"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093493742","display_name":"Sarah Wagmeister","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799894082","display_name":"Franciscan Health","ror":"https://ror.org/01hbes477","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799894082"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah Wagmeister","raw_affiliation_strings":["Franciscan Health Olympia Fields, Chicago, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Franciscan Health Olympia Fields, Chicago, IL","institution_ids":["https://openalex.org/I2799894082"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030884381","display_name":"Tilemahos Spyratos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799894082","display_name":"Franciscan Health","ror":"https://ror.org/01hbes477","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799894082"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tilemahos Spyratos","raw_affiliation_strings":["Franciscan Health Olympia Fields, Chicago, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Franciscan Health Olympia Fields, Chicago, IL","institution_ids":["https://openalex.org/I2799894082"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5042338665"],"corresponding_institution_ids":[],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"119","issue":"10S","first_page":"S2496","last_page":"S2496"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11378","display_name":"Gastrointestinal Bleeding Diagnosis and Treatment","score":0.7651000022888184,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11378","display_name":"Gastrointestinal Bleeding Diagnosis and Treatment","score":0.7651000022888184,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.1639000028371811,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.00430000014603138,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heyde-syndrome","display_name":"Heyde syndrome","score":0.9290000200271606},{"id":"https://openalex.org/keywords/acquired-von-willebrand-syndrome","display_name":"acquired von Willebrand syndrome","score":0.9739999771118164},{"id":"https://openalex.org/keywords/aortic-stenosis","display_name":"aortic stenosis","score":0.8579999804496765},{"id":"https://openalex.org/keywords/gastrointestinal-bleeding","display_name":"gastrointestinal bleeding","score":0.9449999928474426},{"id":"https://openalex.org/keywords/melena","display_name":"melena","score":0.7039999961853027},{"id":"https://openalex.org/keywords/gastric-ulcer","display_name":"gastric ulcer","score":0.6079999804496765},{"id":"https://openalex.org/keywords/erosive-gastropathy","display_name":"erosive gastropathy","score":0.7860000133514404},{"id":"https://openalex.org/keywords/acquired-coagulopathy","display_name":"acquired coagulopathy","score":0.7429999709129333},{"id":"https://openalex.org/keywords/hemophilia-a","display_name":"hemophilia A","score":0.6570000052452087},{"id":"https://openalex.org/keywords/vwf-multimer-analysis","display_name":"VWF multimer analysis","score":0.7559999823570251},{"id":"https://openalex.org/keywords/aortic-valve-replacement","display_name":"aortic valve replacement","score":0.7919999957084656},{"id":"https://openalex.org/keywords/iron-deficiency-anemia","display_name":"iron deficiency anemia","score":0.6510000228881836},{"id":"https://openalex.org/keywords/angiodysplasia","display_name":"angiodysplasia","score":0.7540000081062317},{"id":"https://openalex.org/keywords/aortic-valve-gradient","display_name":"aortic valve gradient","score":0.4699999988079071}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9426717758178711},{"id":"https://openalex.org/C2779936836","wikidata":"https://www.wikidata.org/wiki/Q890200","display_name":"Coagulopathy","level":2,"score":0.7830097675323486},{"id":"https://openalex.org/C2778080469","wikidata":"https://www.wikidata.org/wiki/Q1495657","display_name":"Gastrointestinal bleeding","level":2,"score":0.73213791847229},{"id":"https://openalex.org/C2909910413","wikidata":"https://www.wikidata.org/wiki/Q823027","display_name":"Consumptive Coagulopathy","level":3,"score":0.42146438360214233},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.2971153259277344},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2956128716468811}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.14309/01.ajg.0001044616.56420.d0","doi":"https://doi.org/10.14309/01.ajg.0001044616.56420.d0","is_oa":false,"landing_page_url":"https://doi.org/10.14309/01.ajg.0001044616.56420.d0","pdf_url":null,"source":{"id":"https://openalex.org/S66441642","display_name":"The American Journal of Gastroenterology","issn_l":"0002-9270","issn":["0002-9270","1572-0241"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Gastroenterology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4387733672","https://openalex.org/W7167708161","https://openalex.org/W4408899816","https://openalex.org/W2978630178","https://openalex.org/W2978382638","https://openalex.org/W4220963325","https://openalex.org/W2151364565","https://openalex.org/W7140704121","https://openalex.org/W3130490083","https://openalex.org/W4234286767"],"abstract_inverted_index":{"Introduction:":[0],"Heyde":[1,91,284,335,370],"syndrome":[2,19,28,92,336,371],"is":[3,29,41,102,243],"a":[4,9,88,129,178,183,286,291,311,354],"rare":[5,27],"disorder":[6],"characterized":[7],"by":[8,63],"triad":[10],"of":[11,36,57,74,78,90,97,133,204,250,280,296,334,339,369],"gastrointestinal":[12],"angiodysplasia":[13],"or":[14],"ulcers,":[15],"acquired":[16,320],"von":[17,287],"Willebrand":[18,60,288],"(VS),":[20],"and":[21,40,55,76,113,120,146,169,190,220,241,263,343,367],"aortic":[22,67,228],"stenosis":[23,64],"(AS).":[24],"This":[25,100],"exceptionally":[26],"noted":[30],"to":[31,50,104,106,116,197,212,270,274,352],"be":[32,271],"present":[33,87],"in":[34,44,65,313,384],"1-3%":[35],"patients":[37,45],"with":[38,71,93,128,143,182,225,252,300,310,337,358,361],"AS,":[39],"often":[42],"diagnosed":[43],"over":[46],"age":[47],"65.":[48],"Due":[49],"increased":[51],"circulatory":[52],"shear":[53],"forces":[54],"cleavage":[56],"large":[58],"Von":[59],"multimers":[61,317],"caused":[62],"the":[66,72,84,202,207,215,248,278],"valve":[68,229,232],"(AV),":[69],"interference":[70],"inhibition":[73],"angiogenesis":[75],"delivery":[77],"clotting":[79,294,345],"factor":[80,292],"VIII":[81,293],"ensues":[82],"throughout":[83],"body.":[85],"We":[86,329],"case":[89,101,111],"no":[94],"family":[95],"history":[96,132],"bleeding":[98,205],"disorders.":[99],"relevant":[103],"add":[105,353],"medical":[107,131],"literature":[108],"an":[109,305,319,331],"uncommon":[110],"presentation":[112,333],"subsequent":[114],"management":[115,368],"allow":[117],"for":[118,148,165,254,267,283,364],"prompt":[119,365],"early":[121],"diagnosis.":[122],"Case":[123],"Description/Methods:":[124],"A":[125],"65-year-old":[126],"female":[127],"past":[130],"Iron":[134],"deficiency":[135],"anemia,":[136,341],"RA,":[137],"Type":[138],"2":[139],"diabetes":[140],"mellitus":[141],"presented":[142],"exertional":[144,213],"dyspnea":[145],"dizziness":[147],"two":[149],"weeks.":[150],"Initial":[151],"workup":[152],"revealed":[153,222],"HGB":[154],"5.1,":[155],"HCT":[156],"16.5,":[157],"RDW":[158],"16.6.":[159],"After":[160],"resuscitation,":[161],"gastroenterology":[162],"was":[163,195,234],"consulted":[164],"given":[166,196,258],"significant":[167],"anemia":[168,251],"melena.":[170],"The":[171,322],"patient":[172,216,323],"underwent":[173,217,324],"esophagogastroduodenoscopy":[174],"(EGD)":[175],"which":[176],"showed":[177],"non-bleeding":[179],"gastric":[180],"ulcer":[181,185,378],"clean":[184],"base":[186],"(Forrest":[187,379],"class":[188],"III)":[189],"erosive":[191],"gastropathy.":[192],"Consideration":[193],"also":[194],"potential":[198,253],"angiodysplastic":[199],"lesions":[200],"as":[201],"source":[203],"from":[206],"small":[208],"intestine.":[209],"Concurrently,":[210],"due":[211],"dyspnea,":[214],"cardiological":[218],"evaluation":[219,269],"echocardiogram":[221],"severe":[223,340],"AS":[224],"severely":[226],"reduced":[227],"excursion.":[230],"Aortic":[231],"gradient":[233],"50":[235],"mmHg":[236],"(normal":[237,245,298],"<":[238],"5":[239],"mmHg)":[240],"V-max":[242],"4.78m/s":[244],"1.0m/s).":[246],"Given":[247],"severity":[249],"further":[255],"cardiac":[256,275],"intervention":[257],"valvular":[259],"abnormalities,":[260],"risk":[261],"stratification":[262],"interdisciplinary":[264,359],"discussion":[265],"yielded":[266],"luminal":[268],"completed":[272],"prior":[273],"intervention.":[276],"With":[277,347],"constellation":[279],"findings":[281],"concerning":[282],"syndrome,":[285],"assay":[289],"demonstrated":[290],"time":[295],"218":[297],"50-180%),":[299],"final":[301],"pathology":[302],"report":[303],"showing":[304],"abnormal":[306,344],"VWF":[307],"multimeric":[308],"study":[309],"decrease":[312],"high":[314],"molecular":[315],"weight":[316],"representing":[318],"VS.":[321],"surgical":[325],"AV":[326],"replacement.":[327],"Discussion:":[328],"highlight":[330],"unusual":[332],"symptoms":[338],"melena,":[342],"studies.":[346],"this":[348],"case,":[349],"we":[350],"hope":[351],"step-wise":[355],"approach,":[356],"along":[357],"communication":[360],"care":[362],"teams":[363],"recognition":[366],"(see":[372],"Figure":[373],"1).Figure":[374],"1.:":[375],"Non-bleeding":[376],"pre-pyloric":[377],"Class":[380],"III):":[381],"6":[382],"mm":[383],"diameter.":[385]},"counts_by_year":[],"updated_date":"2026-09-25T08:18:29.962427","created_date":"2024-10-25T00:00:00"}