{"id":"https://openalex.org/W4403721729","doi":"https://doi.org/10.14309/01.ajg.0001046600.18496.06","title":"S4308 Unmasking Zieve Syndrome: A Rare Triad in Alcohol Abuse","display_name":"S4308 Unmasking Zieve Syndrome: A Rare Triad in Alcohol Abuse","publication_year":2024,"publication_date":"2024-10-01","ids":{"openalex":"https://openalex.org/W4403721729","doi":"https://doi.org/10.14309/01.ajg.0001046600.18496.06"},"language":"en","primary_location":{"id":"doi:10.14309/01.ajg.0001046600.18496.06","doi":"https://doi.org/10.14309/01.ajg.0001046600.18496.06","is_oa":false,"landing_page_url":"https://doi.org/10.14309/01.ajg.0001046600.18496.06","pdf_url":null,"source":{"id":"https://openalex.org/S66441642","display_name":"The American Journal of Gastroenterology","issn_l":"0002-9270","issn":["0002-9270","1572-0241"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034817184","display_name":"Hamza Saber","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hamza Saber","raw_affiliation_strings":["The Wright Center for Community Health, Scranton, PA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Wright Center for Community Health, Scranton, PA;","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113193369","display_name":"M.F. Iftikhar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210101997","display_name":"The Wright Center for Graduate Medical Education","ror":"https://ror.org/017ph0q89","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210101997"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mohammad Faisal Iftikhar","raw_affiliation_strings":["Wright Center for Graduate Medical Education, Scranton, PA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wright Center for Graduate Medical Education, Scranton, PA;","institution_ids":["https://openalex.org/I4210101997"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059535381","display_name":"Mohammad Jawed Jawad","orcid":"https://orcid.org/0009-0006-7569-6454","observed_orcids":["https://orcid.org/0009-0006-7569-6454"]},"institutions":[{"id":"https://openalex.org/I4210132235","display_name":"Medical University of the Americas","ror":"https://ror.org/02ma9y414","country_code":"KN","type":"education","lineage":["https://openalex.org/I4210132235"]}],"countries":["KN"],"is_corresponding":false,"raw_author_name":"Mohammad Jawad","raw_affiliation_strings":["Medical University of the Americas, Elmont, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical University of the Americas, Elmont, NY","institution_ids":["https://openalex.org/I4210132235"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061004063","display_name":"Ahmed Algohiny","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ahmed Algohiny","raw_affiliation_strings":["The Wright Center for Community Health, Scranton, PA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Wright Center for Community Health, Scranton, PA;","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5107434227","display_name":"KIRELOS YOUNAN","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kirelos Younan","raw_affiliation_strings":["The Wright Center for Community Health, Scranton, PA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Wright Center for Community Health, Scranton, PA;","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5113193369"],"corresponding_institution_ids":["https://openalex.org/I4210101997"],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"119","issue":"10S","first_page":"S2769","last_page":"S2769"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.7310000061988831,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.7310000061988831,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.04839999973773956,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12068","display_name":"Neonatal Health and Biochemistry","score":0.027300000190734863,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alcoholic-hepatitis","display_name":"alcoholic hepatitis","score":0.5960000157356262},{"id":"https://openalex.org/keywords/jaundice","display_name":"jaundice","score":0.7179999947547913},{"id":"https://openalex.org/keywords/hemolytic-anemia","display_name":"hemolytic anemia","score":0.9350000023841858},{"id":"https://openalex.org/keywords/hyperlipidemia","display_name":"hyperlipidemia","score":0.9610000252723694},{"id":"https://openalex.org/keywords/alcohol-cessation","display_name":"alcohol cessation","score":0.5460000038146973},{"id":"https://openalex.org/keywords/methylprednisolone","display_name":"methylprednisolone","score":0.8529999852180481},{"id":"https://openalex.org/keywords/corticosteroid-therapy","display_name":"corticosteroid therapy","score":0.9179999828338623},{"id":"https://openalex.org/keywords/alcoholic-liver-disease","display_name":"alcoholic liver disease","score":0.6370000243186951},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.5799999833106995},{"id":"https://openalex.org/keywords/hepatic-steatosis","display_name":"hepatic steatosis","score":0.4830000102519989},{"id":"https://openalex.org/keywords/elevated-triglycerides","display_name":"triglyceride elevation","score":0.6019999980926514},{"id":"https://openalex.org/keywords/haptoglobin","display_name":"haptoglobin","score":0.6420000195503235},{"id":"https://openalex.org/keywords/reticulocyte-count","display_name":"reticulocyte count","score":0.9200000166893005},{"id":"https://openalex.org/keywords/healthcare-cost-reduction","display_name":"healthcare cost reduction","score":0.6010000109672546}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9588698148727417},{"id":"https://openalex.org/C176038584","wikidata":"https://www.wikidata.org/wiki/Q626432","display_name":"Triad (sociology)","level":2,"score":0.6757768988609314},{"id":"https://openalex.org/C2781066024","wikidata":"https://www.wikidata.org/wiki/Q156","display_name":"Alcohol","level":2,"score":0.49012407660484314},{"id":"https://openalex.org/C2780931562","wikidata":"https://www.wikidata.org/wiki/Q7331102","display_name":"Alcohol abuse","level":2,"score":0.4780429005622864},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.37469038367271423},{"id":"https://openalex.org/C545542383","wikidata":"https://www.wikidata.org/wiki/Q2751242","display_name":"Medical emergency","level":1,"score":0.3315761685371399},{"id":"https://openalex.org/C11171543","wikidata":"https://www.wikidata.org/wiki/Q41630","display_name":"Psychoanalysis","level":1,"score":0.08549895882606506},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.14309/01.ajg.0001046600.18496.06","doi":"https://doi.org/10.14309/01.ajg.0001046600.18496.06","is_oa":false,"landing_page_url":"https://doi.org/10.14309/01.ajg.0001046600.18496.06","pdf_url":null,"source":{"id":"https://openalex.org/S66441642","display_name":"The American Journal of Gastroenterology","issn_l":"0002-9270","issn":["0002-9270","1572-0241"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Gastroenterology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2978448511","https://openalex.org/W7162326179","https://openalex.org/W4403721496","https://openalex.org/W4413099980","https://openalex.org/W7114770941","https://openalex.org/W2977336697","https://openalex.org/W7025294259","https://openalex.org/W4417238944","https://openalex.org/W7113907350","https://openalex.org/W2979967146"],"abstract_inverted_index":{"Introduction:":[0],"Jaundice":[1],"in":[2,8,71,259,304,351],"alcoholic":[3,94,293],"patients":[4,72,305],"is":[5,11,27,39],"often":[6],"multifactorial":[7],"nature":[9],"and":[10,22,48,93,117,127,150,156,176,201,238,245,269,295,310,321],"caused":[12],"by":[13,44,63],"a":[14,40,74,86,311,340],"combination":[15],"of":[16,31,67,76,90,100,159,167,209,255,300,313,323,328,330,348,354],"liver":[17,198],"dysfunction,":[18],"ineffective":[19],"bilirubin":[20,123,129,216,242],"processing,":[21],"poor":[23],"nutrition.":[24],"However,":[25,335],"there":[26],"also":[28,135],"another":[29],"cause":[30],"jaundice":[32],"which":[33,160],"goes":[34],"underdiagnosed.":[35],"Zieve":[36],"syndrome":[37,70],"[ZS]":[38],"rare":[41],"condition":[42],"characterized":[43],"hemolytic":[45],"anemia,":[46],"hyperlipidemia,":[47],"transient":[49],"jaundice.":[50,101],"This":[51,249],"case":[52,250,337],"report":[53,251,338],"aims":[54],"to":[55,57,218,279],"contribute":[56],"the":[58,65,168,253,260,319,346,352],"limited":[59],"literature":[60],"on":[61,105,220],"ZS":[62,257,274,303,331],"highlighting":[64],"importance":[66,208,254],"considering":[68],"this":[69],"with":[73,85,181,241,284,289,307],"history":[75,89,312],"significant":[77],"alcohol":[78,91,210,315,333],"use.":[79],"Case":[80],"Description/Methods:":[81],"A":[82,164,193,297],"22-year-old":[83],"woman":[84],"past":[87],"medical":[88],"abuse":[92,316],"hepatitis":[95,142,294],"was":[96,124,130,191,212,229],"admitted":[97],"for":[98,146,302,342],"evaluation":[99],"Recent":[102],"blood":[103],"work":[104],"outpatient":[106,221],"setting":[107],"showed":[108,170,233],"ALP":[109],"at":[110,114,119],"131":[111],"U/L,":[112,116],"AST":[113],"67":[115],"ALT":[118],"24":[120],"U/L.":[121],"Total":[122],"12.3":[125],"mg/dL":[126],"direct":[128],"7.5":[131],"mg/dL.":[132,225],"Triglycerides":[133],"were":[134,179,204],"elevated.":[136],"Further":[137],"testing":[138,268],"included":[139],"alpha-1":[140],"antitrypsin,":[141],"serologies,":[143],"ceruloplasmin,":[144],"tests":[145],"hemochromatosis,":[147],"anti-smooth":[148],"muscle":[149],"antimitochondrial":[151],"antibodies,":[152],"Epstein":[153],"Barr":[154],"Virus,":[155],"cytomegalovirus,":[157],"all":[158],"came":[161],"back":[162],"normal.":[163],"CT":[165],"scan":[166],"abdomen":[169],"an":[171],"enlarged":[172],"fatty":[173],"liver.":[174],"Haptoglobin":[175],"reticulocyte":[177],"counts":[178],"consistent":[180],"hemolysis":[182],"however":[183],"hemoglobin":[184],"remained":[185],"stable":[186],"throughout":[187],"hospital":[188],"stay.":[189],"Gastroenterology":[190],"consulted.":[192],"wide":[194],"differential":[195],"including":[196],"inherent":[197],"disease,":[199],"hepatitis,":[200],"autoimmune":[202],"conditions":[203],"ruled":[205],"out.":[206],"The":[207,214,231,326],"cessation":[211],"emphasized.":[213],"patient's":[215],"continued":[217],"rise":[219],"follow-ups,":[222],"reaching":[223],"20":[224],"Consequently,":[226],"methylprednisolone":[227],"therapy":[228,350],"initiated.":[230],"patient":[232],"improvement":[234],"after":[235],"being":[236],"abstinent":[237],"starting":[239],"steroids,":[240],"levels":[243],"decreasing":[244],"eventually":[246],"normalizing.":[247],"Discussion:":[248],"highlights":[252],"recognizing":[256],"early":[258],"diagnostic":[261],"process,":[262],"as":[263,292],"it":[264],"can":[265,275,317],"reduce":[266],"unnecessary":[267],"associated":[270,288],"healthcare":[271],"costs.":[272],"Diagnosing":[273],"be":[276],"challenging":[277],"due":[278],"its":[280],"overlapping":[281],"clinical":[282],"features":[283],"other":[285],"hepatic":[286],"disorders":[287],"alcoholism,":[290],"such":[291],"cirrhosis.":[296],"high":[298],"index":[299],"suspicion":[301],"presenting":[306],"characteristic":[308],"symptoms":[309],"chronic":[314],"expedite":[318],"diagnosis":[320],"initiation":[322],"appropriate":[324],"management.":[325],"mainstay":[327],"treatment":[329],"remains":[332],"cessation.":[334],"our":[336],"provides":[339],"basis":[341],"further":[343],"investigation":[344],"into":[345],"role":[347],"steroid":[349],"management":[353],"ZS.":[355]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-10-25T00:00:00"}