{"id":"https://openalex.org/W4403719672","doi":"https://doi.org/10.1145/3664647.3681425","title":"Agent Aggregator with Mask Denoise Mechanism for Histopathology Whole Slide Image Analysis","display_name":"Agent Aggregator with Mask Denoise Mechanism for Histopathology Whole Slide Image Analysis","publication_year":2024,"publication_date":"2024-10-26","ids":{"openalex":"https://openalex.org/W4403719672","doi":"https://doi.org/10.1145/3664647.3681425"},"language":"en","primary_location":{"id":"doi:10.1145/3664647.3681425","doi":"https://doi.org/10.1145/3664647.3681425","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3664647.3681425","pdf_url":null,"source":{"id":"https://openalex.org/S4363608757","display_name":"ACM International Conference on Multimedia (ACM MM)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 32nd ACM International Conference on Multimedia","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","is_traditional":true,"indexed_in":["arxiv","crossref","datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://arxiv.org/pdf/2409.11664","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111335051","display_name":"Xitong Ling","orcid":"https://orcid.org/0009-0008-2016-5255","observed_orcids":["https://orcid.org/0009-0008-2016-5255"]},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xitong Ling","raw_affiliation_strings":["Tsinghua University, Shenzhen, China"],"raw_orcid":"https://orcid.org/0009-0008-2016-5255","affiliations":[{"raw_affiliation_string":"Tsinghua University, Shenzhen, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062005921","display_name":"Minxi Ouyang","orcid":"https://orcid.org/0009-0007-5992-0919","observed_orcids":["https://orcid.org/0009-0007-5992-0919"]},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Minxi Ouyang","raw_affiliation_strings":["Tsinghua University, Shenzhen, China"],"raw_orcid":"https://orcid.org/0009-0007-5992-0919","affiliations":[{"raw_affiliation_string":"Tsinghua University, Shenzhen, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102886823","display_name":"Yizhi Wang","orcid":"https://orcid.org/0009-0004-2619-8235","observed_orcids":["https://orcid.org/0009-0004-2619-8235"]},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yizhi Wang","raw_affiliation_strings":["Tsinghua University, Shenzhen, China"],"raw_orcid":"https://orcid.org/0009-0004-2619-8235","affiliations":[{"raw_affiliation_string":"Tsinghua University, Shenzhen, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046671377","display_name":"Xinrui Chen","orcid":"https://orcid.org/0009-0002-8053-8494","observed_orcids":["https://orcid.org/0009-0002-8053-8494"]},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinrui Chen","raw_affiliation_strings":["Tsinghua University, Shenzhen, China"],"raw_orcid":"https://orcid.org/0009-0002-8053-8494","affiliations":[{"raw_affiliation_string":"Tsinghua University, Shenzhen, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049935860","display_name":"Renao Yan","orcid":"https://orcid.org/0000-0002-2399-199X","observed_orcids":["https://orcid.org/0000-0002-2399-199X"]},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Renao Yan","raw_affiliation_strings":["Tsinghua University, Shenzhen, China"],"raw_orcid":"https://orcid.org/0000-0002-2399-199X","affiliations":[{"raw_affiliation_string":"Tsinghua University, Shenzhen, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086506020","display_name":"Hongbo Chu","orcid":"https://orcid.org/0009-0005-5870-3133","observed_orcids":["https://orcid.org/0009-0005-5870-3133"]},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongbo Chu","raw_affiliation_strings":["Tsinghua University, Shenzhen, China"],"raw_orcid":"https://orcid.org/0009-0005-5870-3133","affiliations":[{"raw_affiliation_string":"Tsinghua University, Shenzhen, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Junru Cheng","orcid":"https://orcid.org/0009-0008-0160-294X","observed_orcids":["https://orcid.org/0009-0008-0160-294X"]},"institutions":[{"id":"https://openalex.org/I4405261323","display_name":"Research Institute of Tsinghua University in Shenzhen","ror":"https://ror.org/0543pw950","country_code":"CN","type":"education","lineage":["https://openalex.org/I4405261323"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junru Cheng","raw_affiliation_strings":["Research Institute of Tsinghua, Shenzhen, China"],"raw_orcid":"https://orcid.org/0009-0008-0160-294X","affiliations":[{"raw_affiliation_string":"Research Institute of Tsinghua, Shenzhen, China","institution_ids":["https://openalex.org/I4405261323"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109583386","display_name":"Tian Guan","orcid":"https://orcid.org/0000-0003-2509-2952","observed_orcids":["https://orcid.org/0000-0003-2509-2952","https://orcid.org/0000-0003-3989-6927"]},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tian Guan","raw_affiliation_strings":["Tsinghua University, Shenzhen, China"],"raw_orcid":"https://orcid.org/0000-0003-2509-2952","affiliations":[{"raw_affiliation_string":"Tsinghua University, Shenzhen, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101435223","display_name":"Sufang Tian","orcid":"https://orcid.org/0000-0002-3025-666X","observed_orcids":["https://orcid.org/0000-0002-3025-666X"]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Sufang Tian","raw_affiliation_strings":["Wuhan University, Wuhan, China"],"raw_orcid":"https://orcid.org/0000-0002-3025-666X","affiliations":[{"raw_affiliation_string":"Wuhan University, Wuhan, China","institution_ids":["https://openalex.org/I37461747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100397101","display_name":"Xiaoping Liu","orcid":"https://orcid.org/0000-0001-6179-0964","observed_orcids":["https://orcid.org/0000-0001-6179-0964"]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoping Liu","raw_affiliation_strings":["Wuhan University, Wuhan, China"],"raw_orcid":"https://orcid.org/0000-0001-6179-0964","affiliations":[{"raw_affiliation_string":"Wuhan University, Wuhan, China","institution_ids":["https://openalex.org/I37461747"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100719304","display_name":"Yonghong He","orcid":"https://orcid.org/0000-0002-9964-8901","observed_orcids":["https://orcid.org/0000-0002-9964-8901"]},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yonghong He","raw_affiliation_strings":["Tsinghua University, Shenzhen, China"],"raw_orcid":"https://orcid.org/0000-0002-9964-8901","affiliations":[{"raw_affiliation_string":"Tsinghua University, Shenzhen, China","institution_ids":["https://openalex.org/I99065089"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.9994,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.93611205,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":null,"issue":null,"first_page":"2795","last_page":"2803"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/whole-slide-image-classification","display_name":"whole slide image classification","score":0.7950000166893005},{"id":"https://openalex.org/keywords/histopathology","display_name":"histopathology","score":0.8169999718666077},{"id":"https://openalex.org/keywords/multiple-instance-learning","display_name":"multiple instance learning","score":0.9660000205039978},{"id":"https://openalex.org/keywords/attention-mechanism","display_name":"attention mechanism","score":0.734000027179718},{"id":"https://openalex.org/keywords/weakly-supervised-learning","display_name":"weakly supervised learning","score":0.8870000243186951},{"id":"https://openalex.org/keywords/interpretability","display_name":"interpretability","score":0.800000011920929}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7717324495315552},{"id":"https://openalex.org/C2781067378","wikidata":"https://www.wikidata.org/wiki/Q17027399","display_name":"Interpretability","level":2,"score":0.762298583984375},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5705986618995667},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4777604639530182},{"id":"https://openalex.org/C180505990","wikidata":"https://www.wikidata.org/wiki/Q498267","display_name":"News aggregator","level":2,"score":0.4397764801979065},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.4154221713542938},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.35209280252456665},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1145/3664647.3681425","doi":"https://doi.org/10.1145/3664647.3681425","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3664647.3681425","pdf_url":null,"source":{"id":"https://openalex.org/S4363608757","display_name":"ACM International Conference on Multimedia (ACM MM)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 32nd ACM International Conference on Multimedia","raw_type":"proceedings-article"},{"id":"pmh:oai:arXiv.org:2409.11664","doi":null,"is_oa":true,"landing_page_url":"http://arxiv.org/abs/2409.11664","pdf_url":"https://arxiv.org/pdf/2409.11664","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"doi:10.48550/arxiv.2409.11664","doi":"https://doi.org/10.48550/arxiv.2409.11664","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.2409.11664","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"pmh:oai:arXiv.org:2409.11664","doi":null,"is_oa":true,"landing_page_url":"http://arxiv.org/abs/2409.11664","pdf_url":"https://arxiv.org/pdf/2409.11664","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G8841627581","display_name":null,"funder_award_id":"KCXFZ202012211173207022","funder_id":"https://openalex.org/F4320317337","funder_display_name":"Science and Technology Foundation of Shenzhen City"}],"funders":[{"id":"https://openalex.org/F4320317337","display_name":"Science and Technology Foundation of Shenzhen City","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4403719672.pdf","grobid_xml":"https://content.openalex.org/works/W4403719672.grobid-xml"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W2108598243","https://openalex.org/W2194775991","https://openalex.org/W2531897166","https://openalex.org/W2998175747","https://openalex.org/W3018295606","https://openalex.org/W3089090082","https://openalex.org/W3145450063","https://openalex.org/W3173365702","https://openalex.org/W3176719058","https://openalex.org/W4291652743","https://openalex.org/W4312468136","https://openalex.org/W4312765357","https://openalex.org/W4386076358","https://openalex.org/W4387259074","https://openalex.org/W4390873172","https://openalex.org/W4390873368","https://openalex.org/W4390874124","https://openalex.org/W4402716046","https://openalex.org/W4402716098","https://openalex.org/W4403944333"],"related_works":["https://openalex.org/W7167895886","https://openalex.org/W4399455468","https://openalex.org/W4387827249","https://openalex.org/W4409262812","https://openalex.org/W7163521210","https://openalex.org/W7125429820","https://openalex.org/W4405786656","https://openalex.org/W4410251272","https://openalex.org/W4413194488","https://openalex.org/W4380446840"],"abstract_inverted_index":{"Histopathology":[0],"analysis":[1,40],"is":[2,60],"the":[3,31,109],"gold":[4],"standard":[5],"for":[6,54,69,113],"medical":[7],"diagnosis.":[8,24],"Accurate":[9],"classification":[10,38],"of":[11,28,33],"whole":[12],"slide":[13],"images":[14],"(WSIs)":[15],"and":[16,30,39,79,111,118,129,145,154],"region-of-interests":[17],"(ROIs)":[18],"localization":[19],"can":[20],"assist":[21],"pathologists":[22],"in":[23,143],"The":[25,57,100],"gigapixel":[26],"resolution":[27],"WSI":[29,55],"absence":[32],"fine-grained":[34],"annotations":[35],"make":[36],"direct":[37],"challenging.":[41],"In":[42],"weakly":[43],"supervised":[44],"learning,":[45],"multiple":[46],"instance":[47,67,115],"learning":[48],"(MIL)":[49],"presents":[50],"a":[51,96],"promising":[52],"approach":[53],"classification.":[56,70],"prevailing":[58],"strategy":[59],"to":[61,65,75],"use":[62],"attention":[63,72,135],"mechanisms":[64,73],"measure":[66],"importance":[68],"However,":[71],"fail":[74],"capture":[76],"inter-instance":[77],"information,":[78],"self-attention":[80],"causes":[81],"quadratic":[82],"computational":[83],"complexity.":[84],"To":[85],"address":[86],"these":[87],"challenges,":[88],"we":[89],"propose":[90],"AMD-MIL,":[91],"an":[92,105],"agent":[93,101],"aggregator":[94],"with":[95],"mask":[97,126],"denoise":[98],"mechanism.":[99],"token":[102],"acts":[103],"as":[104],"intermediate":[106],"variable":[107],"between":[108],"query":[110],"key":[112],"computing":[114],"importance.":[116],"Mask":[117],"denoising":[119],"matrices,":[120],"mapped":[121],"from":[122],"agents-aggregated":[123],"value,":[124],"dynamically":[125],"low-contribution":[127],"representations":[128],"eliminate":[130],"noise.":[131],"AMD-MIL":[132],"achieves":[133],"better":[134],"allocation":[136],"by":[137],"adjusting":[138],"feature":[139],"representations,":[140],"capturing":[141],"micro-metastases":[142],"cancer,":[144],"improving":[146],"interpretability.":[147],"Extensive":[148],"experiments":[149],"on":[150],"CAMELYON-16,":[151],"CAMELYON-17,":[152],"TCGA-KIDNEY,":[153],"TCGA-LUNG":[155],"show":[156],"AMD-MIL's":[157],"superiority":[158],"over":[159],"state-of-the-art":[160],"methods.":[161]},"counts_by_year":[{"year":2026,"cited_by_count":11},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2024-10-25T00:00:00"}