{"id":"https://openalex.org/W4403665595","doi":"https://doi.org/10.1016/j.ygyno.2024.10.001","title":"Phase II study of enlonstobart (SG001), a novel PD-1 inhibitor in patients with PD-L1 positive recurrent/metastatic cervical cancer","display_name":"Phase II study of enlonstobart (SG001), a novel PD-1 inhibitor in patients with PD-L1 positive recurrent/metastatic cervical cancer","publication_year":2024,"publication_date":"2024-10-23","ids":{"openalex":"https://openalex.org/W4403665595","doi":"https://doi.org/10.1016/j.ygyno.2024.10.001","pmid":"https://pubmed.ncbi.nlm.nih.gov/39447517"},"language":"en","primary_location":{"id":"doi:10.1016/j.ygyno.2024.10.001","doi":"https://doi.org/10.1016/j.ygyno.2024.10.001","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ygyno.2024.10.001","pdf_url":"https://www.gynecologiconcology-online.net/article/S0090-8258(24)01150-8/pdf","source":{"id":"https://openalex.org/S2574783","display_name":"Gynecologic Oncology","issn_l":"0090-8258","issn":["0090-8258","1095-6859"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gynecologic Oncology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.gynecologiconcology-online.net/article/S0090-8258(24)01150-8/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100657167","display_name":"Guiling Li","orcid":"https://orcid.org/0000-0002-3220-7554","observed_orcids":["https://orcid.org/0000-0002-3220-7554"]},"institutions":[{"id":"https://openalex.org/I4210129222","display_name":"Wuhan Union Hospital","ror":"https://ror.org/0371fqr87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210129222"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guiling Li","raw_affiliation_strings":["Department of Gynecologic Oncology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecologic Oncology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China","institution_ids":["https://openalex.org/I4210129222","https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100637076","display_name":"Xiaofan Li","orcid":"https://orcid.org/0000-0001-9202-5499","observed_orcids":["https://orcid.org/0000-0001-9202-5499"]},"institutions":[{"id":"https://openalex.org/I4210093964","display_name":"Peking University Cancer Hospital","ror":"https://ror.org/00nyxxr91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093964"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaofan Li","raw_affiliation_strings":["Department of Gynecologic Oncology, Linyi Cancer Hospital, Linyi, Shandong, China","Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital & Institute, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecologic Oncology, Linyi Cancer Hospital, Linyi, Shandong, China","institution_ids":[]},{"raw_affiliation_string":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital & Institute, Beijing, China","institution_ids":["https://openalex.org/I4210093964"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090765880","display_name":"Rutie Yin","orcid":"https://orcid.org/0000-0002-9221-6727","observed_orcids":["https://orcid.org/0000-0002-9221-6727","https://orcid.org/0000-0001-6999-665X"]},"institutions":[{"id":"https://openalex.org/I4210089228","display_name":"West China Second University Hospital of Sichuan University","ror":"https://ror.org/00726et14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089228"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rutie Yin","raw_affiliation_strings":["Department of Obstetrics and Gynecology, West China Second University Hospital, Chengdu, Sichuan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, West China Second University Hospital, Chengdu, Sichuan, China","institution_ids":["https://openalex.org/I4210089228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044239966","display_name":"Mei Feng","orcid":"https://orcid.org/0000-0002-0078-8809","observed_orcids":["https://orcid.org/0000-0002-0078-8809"]},"institutions":[{"id":"https://openalex.org/I129708740","display_name":"Fujian Medical University","ror":"https://ror.org/050s6ns64","country_code":"CN","type":"education","lineage":["https://openalex.org/I129708740"]},{"id":"https://openalex.org/I4210148548","display_name":"Fujian Provincial Cancer Hospital","ror":"https://ror.org/058ms9w43","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210148548"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mei Feng","raw_affiliation_strings":["Department of Gynecology, Fujian Cancer Hospital & Fujian Medical University Cancer Hospital, Fuzhou, Fujian, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, Fujian Cancer Hospital & Fujian Medical University Cancer Hospital, Fuzhou, Fujian, China","institution_ids":["https://openalex.org/I129708740","https://openalex.org/I4210148548"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jing Zuo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Zuo","raw_affiliation_strings":["Department of Gynecology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018626216","display_name":"Shuqing Wei","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210102673","display_name":"Shanxi Provincial Cancer Hospital","ror":"https://ror.org/01790dx02","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210102673"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuqing Wei","raw_affiliation_strings":["Department of Geriatrics, Shanxi Provincial Cancer Hospital, Taiyuan, Shanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatrics, Shanxi Provincial Cancer Hospital, Taiyuan, Shanxi, China","institution_ids":["https://openalex.org/I4210102673"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101586481","display_name":"Shan Kang","orcid":"https://orcid.org/0000-0001-7790-2393","observed_orcids":["https://orcid.org/0000-0001-7790-2393"]},"institutions":[{"id":"https://openalex.org/I111381250","display_name":"Hebei Medical University","ror":"https://ror.org/04eymdx19","country_code":"CN","type":"education","lineage":["https://openalex.org/I111381250"]},{"id":"https://openalex.org/I4210106405","display_name":"Fourth Hospital of Hebei Medical University","ror":"https://ror.org/01mdjbm03","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106405"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shan Kang","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Hebei Medical University Fourth Affiliated Hospital and Hebei Provincial Tumor Hospital, Shijiazhuang, Hebei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Hebei Medical University Fourth Affiliated Hospital and Hebei Provincial Tumor Hospital, Shijiazhuang, Hebei, China","institution_ids":["https://openalex.org/I111381250","https://openalex.org/I4210106405"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029076691","display_name":"Hongmei Sun","orcid":"https://orcid.org/0000-0002-9253-8857","observed_orcids":["https://orcid.org/0000-0002-9253-8857"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hongmei Sun","raw_affiliation_strings":["Department of Oncology, Jiamusi Cancer and Tuberculosis Hospital, Jiamusi, Heilongjiang, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Jiamusi Cancer and Tuberculosis Hospital, Jiamusi, Heilongjiang, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xiumin Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210093964","display_name":"Peking University Cancer Hospital","ror":"https://ror.org/00nyxxr91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093964"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiumin Li","raw_affiliation_strings":["Department of Gynecologic Oncology, Linyi Cancer Hospital, Linyi, Shandong, China","Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital & Institute, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecologic Oncology, Linyi Cancer Hospital, Linyi, Shandong, China","institution_ids":[]},{"raw_affiliation_string":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital & Institute, Beijing, China","institution_ids":["https://openalex.org/I4210093964"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101667800","display_name":"Yili Wang","orcid":"https://orcid.org/0000-0002-7649-3740","observed_orcids":["https://orcid.org/0000-0002-7649-3740"]},"institutions":[{"id":"https://openalex.org/I4210133784","display_name":"First Affiliated Hospital of Gannan Medical University","ror":"https://ror.org/040gnq226","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210133784"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yili Wang","raw_affiliation_strings":["Department of Oncology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China","institution_ids":["https://openalex.org/I4210133784"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052649748","display_name":"Yunyan Zhang","orcid":"https://orcid.org/0000-0003-3352-4241","observed_orcids":["https://orcid.org/0000-0003-3352-4241","https://orcid.org/0000-0001-8254-5730","https://orcid.org/0000-0002-3658-8200"]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I4210103956","display_name":"Third Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/01f77gp95","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210103956"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yunyan Zhang","raw_affiliation_strings":["Department of Radiation Oncology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China","institution_ids":["https://openalex.org/I156144747","https://openalex.org/I4210103956"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100944312","display_name":"Li Sun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I108688024","display_name":"Qingdao University","ror":"https://ror.org/021cj6z65","country_code":"CN","type":"education","lineage":["https://openalex.org/I108688024"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li Sun","raw_affiliation_strings":["Department of Gynecologic Oncology, The Second Affiliated Hospital of Medical College of Qingdao University, Qingdao Central Hospital, Qingdao, Shandong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecologic Oncology, The Second Affiliated Hospital of Medical College of Qingdao University, Qingdao Central Hospital, Qingdao, Shandong, China","institution_ids":["https://openalex.org/I108688024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100946135","display_name":"Daren Lin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210146741","display_name":"Jiangmen Central Hospital","ror":"https://ror.org/04baw4297","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146741"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Daren Lin","raw_affiliation_strings":["Department of Oncology, Jiangmen Central Hospital, Jiangmen, Guangdong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Jiangmen Central Hospital, Jiangmen, Guangdong, China","institution_ids":["https://openalex.org/I4210146741"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028010098","display_name":"Xiaohong Ruan","orcid":"https://orcid.org/0009-0009-6287-9376","observed_orcids":["https://orcid.org/0009-0009-6287-9376"]},"institutions":[{"id":"https://openalex.org/I4210146741","display_name":"Jiangmen Central Hospital","ror":"https://ror.org/04baw4297","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146741"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaohong Ruan","raw_affiliation_strings":["Department of Oncology, Jiangmen Central Hospital, Jiangmen, Guangdong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Jiangmen Central Hospital, Jiangmen, Guangdong, China","institution_ids":["https://openalex.org/I4210146741"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101702054","display_name":"Zhitu Zhu","orcid":"https://orcid.org/0000-0003-2406-6322","observed_orcids":["https://orcid.org/0000-0003-2406-6322"]},"institutions":[{"id":"https://openalex.org/I85430964","display_name":"Jinzhou Medical University","ror":"https://ror.org/02yd1yr68","country_code":"CN","type":"education","lineage":["https://openalex.org/I85430964"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhitu Zhu","raw_affiliation_strings":["Department of Oncology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China","institution_ids":["https://openalex.org/I85430964"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103120788","display_name":"Kui Jiang","orcid":"https://orcid.org/0000-0002-5487-928X","observed_orcids":["https://orcid.org/0000-0002-5487-928X"]},"institutions":[{"id":"https://openalex.org/I191996457","display_name":"Dalian Medical University","ror":"https://ror.org/04c8eg608","country_code":"CN","type":"education","lineage":["https://openalex.org/I191996457"]},{"id":"https://openalex.org/I4210100868","display_name":"Second Affiliated Hospital of Dalian Medical University","ror":"https://ror.org/012f2cn18","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210100868"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kui Jiang","raw_affiliation_strings":["Department of Oncology, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China","institution_ids":["https://openalex.org/I191996457","https://openalex.org/I4210100868"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024452255","display_name":"Hu Liu","orcid":"https://orcid.org/0000-0002-3952-4165","observed_orcids":["https://orcid.org/0000-0002-3952-4165"]},"institutions":[{"id":"https://openalex.org/I126520041","display_name":"University of Science and Technology of China","ror":"https://ror.org/04c4dkn09","country_code":"CN","type":"education","lineage":["https://openalex.org/I126520041","https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hu Liu","raw_affiliation_strings":["Department of Oncology, The First Affiliated Hospital of USTC, Anhui Provincial Cancer Hospital, Hefei, Anhui, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, The First Affiliated Hospital of USTC, Anhui Provincial Cancer Hospital, Hefei, Anhui, China","institution_ids":["https://openalex.org/I126520041"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064482766","display_name":"Wei Wang","orcid":"https://orcid.org/0000-0001-9354-6931","observed_orcids":["https://orcid.org/0000-0001-9354-6931"]},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]},{"id":"https://openalex.org/I4210133678","display_name":"Second Hospital of Shanxi Medical University","ror":"https://ror.org/03tn5kh37","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210133678"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Wang","raw_affiliation_strings":["Department of Gynecology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China","institution_ids":["https://openalex.org/I17721919","https://openalex.org/I4210133678"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032331566","display_name":"Deshun Hao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387153926","display_name":"CSPC Pharmaceutical Group","ror":"https://ror.org/016mq8947","country_code":"CN","type":"company","lineage":["https://openalex.org/I4387153926"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Deshun Hao","raw_affiliation_strings":["CSPC Zhongqi Pharmaceutical Technology Co., Ltd, Shijiazhuang, Hebei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CSPC Zhongqi Pharmaceutical Technology Co., Ltd, Shijiazhuang, Hebei, China","institution_ids":["https://openalex.org/I4387153926"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069395951","display_name":"Ying Chen","orcid":"https://orcid.org/0000-0001-5833-2380","observed_orcids":["https://orcid.org/0000-0001-5833-2380"]},"institutions":[{"id":"https://openalex.org/I4387153926","display_name":"CSPC Pharmaceutical Group","ror":"https://ror.org/016mq8947","country_code":"CN","type":"company","lineage":["https://openalex.org/I4387153926"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Chen","raw_affiliation_strings":["CSPC Zhongqi Pharmaceutical Technology Co., Ltd, Shijiazhuang, Hebei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CSPC Zhongqi Pharmaceutical Technology Co., Ltd, Shijiazhuang, Hebei, China","institution_ids":["https://openalex.org/I4387153926"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013662095","display_name":"Silong Xiang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387153926","display_name":"CSPC Pharmaceutical Group","ror":"https://ror.org/016mq8947","country_code":"CN","type":"company","lineage":["https://openalex.org/I4387153926"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Silong Xiang","raw_affiliation_strings":["CSPC Zhongqi Pharmaceutical Technology Co., Ltd, Shijiazhuang, Hebei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CSPC Zhongqi Pharmaceutical Technology Co., Ltd, Shijiazhuang, Hebei, China","institution_ids":["https://openalex.org/I4387153926"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052392914","display_name":"Miao Niu","orcid":"https://orcid.org/0000-0003-4685-4549","observed_orcids":["https://orcid.org/0000-0003-4685-4549"]},"institutions":[{"id":"https://openalex.org/I4387153926","display_name":"CSPC Pharmaceutical Group","ror":"https://ror.org/016mq8947","country_code":"CN","type":"company","lineage":["https://openalex.org/I4387153926"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Miao Niu","raw_affiliation_strings":["CSPC Zhongqi Pharmaceutical Technology Co., Ltd, Shijiazhuang, Hebei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CSPC Zhongqi Pharmaceutical Technology Co., Ltd, Shijiazhuang, Hebei, China","institution_ids":["https://openalex.org/I4387153926"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061667981","display_name":"Lingying Wu","orcid":"https://orcid.org/0000-0003-3153-7786","observed_orcids":["https://orcid.org/0000-0003-3153-7786"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I4210141458","display_name":"Cancer Hospital of Chinese Academy of Medical Sciences","ror":"https://ror.org/03x937183","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210141458"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Lingying Wu","raw_affiliation_strings":["Department of Gynecology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Electronic address: wulingying@csco.org.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Electronic address: wulingying@csco.org.cn","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I4210141458"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":23,"corresponding_author_ids":["https://openalex.org/A5061667981"],"corresponding_institution_ids":["https://openalex.org/I200296433","https://openalex.org/I4210141458"],"apc_list":{"value":4060,"currency":"USD","value_usd":4060},"apc_paid":{"value":4060,"currency":"USD","value_usd":4060},"fwci":1.8826,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.87578131,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"191","issue":null,"first_page":"165","last_page":"171"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9258000254631042,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9258000254631042,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10668","display_name":"Endometrial and Cervical Cancer Treatments","score":0.06300000101327896,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":0.005900000222027302,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pd-1-inhibitors","display_name":"PD-1 inhibitors","score":0.8709999918937683},{"id":"https://openalex.org/keywords/anti-pd-1-monoclonal-antibody","display_name":"anti-PD-1 monoclonal antibody","score":0.9330000281333923},{"id":"https://openalex.org/keywords/recurrent-or-metastatic-cervical-cancer","display_name":"recurrent or metastatic cervical cancer","score":0.8830000162124634},{"id":"https://openalex.org/keywords/second-line-treatment","display_name":"second-line therapy","score":0.5440000295639038},{"id":"https://openalex.org/keywords/objective-response-rate","display_name":"objective response rate","score":0.8669999837875366},{"id":"https://openalex.org/keywords/treatment-emergent-adverse-events","display_name":"treatment-emergent adverse events","score":0.8320000171661377},{"id":"https://openalex.org/keywords/immunotherapy","display_name":"immunotherapy","score":0.5019999742507935},{"id":"https://openalex.org/keywords/platinum-refractory-disease","display_name":"platinum-refractory disease","score":0.7319999933242798},{"id":"https://openalex.org/keywords/progression-free-survival","display_name":"progression-free survival","score":0.46799999475479126}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9506251811981201},{"id":"https://openalex.org/C2778220009","wikidata":"https://www.wikidata.org/wiki/Q160105","display_name":"Cervical cancer","level":3,"score":0.5675143599510193},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5594280362129211},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5253312587738037},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5122991800308228}],"mesh":[{"descriptor_ui":"D000077982","descriptor_name":"Progression-Free Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000082082","descriptor_name":"Immune Checkpoint Inhibitors","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000082082","descriptor_name":"Immune Checkpoint Inhibitors","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D000082082","descriptor_name":"Immune Checkpoint Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009362","descriptor_name":"Neoplasm Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D060890","descriptor_name":"B7-H1 Antigen","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D060890","descriptor_name":"B7-H1 Antigen","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D061067","descriptor_name":"Antibodies, Monoclonal, Humanized","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D061067","descriptor_name":"Antibodies, Monoclonal, Humanized","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D061067","descriptor_name":"Antibodies, Monoclonal, Humanized","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.ygyno.2024.10.001","doi":"https://doi.org/10.1016/j.ygyno.2024.10.001","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ygyno.2024.10.001","pdf_url":"https://www.gynecologiconcology-online.net/article/S0090-8258(24)01150-8/pdf","source":{"id":"https://openalex.org/S2574783","display_name":"Gynecologic Oncology","issn_l":"0090-8258","issn":["0090-8258","1095-6859"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gynecologic Oncology","raw_type":"journal-article"},{"id":"pmid:39447517","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39447517","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gynecologic oncology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.ygyno.2024.10.001","doi":"https://doi.org/10.1016/j.ygyno.2024.10.001","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ygyno.2024.10.001","pdf_url":"https://www.gynecologiconcology-online.net/article/S0090-8258(24)01150-8/pdf","source":{"id":"https://openalex.org/S2574783","display_name":"Gynecologic Oncology","issn_l":"0090-8258","issn":["0090-8258","1095-6859"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gynecologic Oncology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4403665595.pdf","grobid_xml":"https://content.openalex.org/works/W4403665595.grobid-xml"},"referenced_works_count":22,"referenced_works":["https://openalex.org/W2006287686","https://openalex.org/W2011887157","https://openalex.org/W2908928362","https://openalex.org/W2925815206","https://openalex.org/W2972117663","https://openalex.org/W3025620009","https://openalex.org/W3194911083","https://openalex.org/W3200231835","https://openalex.org/W4200215773","https://openalex.org/W4210971182","https://openalex.org/W4221092886","https://openalex.org/W4295592568","https://openalex.org/W4296679200","https://openalex.org/W4315754639","https://openalex.org/W4387811398","https://openalex.org/W4387903318","https://openalex.org/W4389229205","https://openalex.org/W4389538263","https://openalex.org/W4390509324","https://openalex.org/W4391671392","https://openalex.org/W4393965986","https://openalex.org/W6857231829"],"related_works":["https://openalex.org/W4399395063","https://openalex.org/W4414649806","https://openalex.org/W4410814077","https://openalex.org/W4404475007","https://openalex.org/W4400963676","https://openalex.org/W4410802619","https://openalex.org/W2890666345","https://openalex.org/W4410813764","https://openalex.org/W4295227163","https://openalex.org/W3194911083"],"abstract_inverted_index":{"BACKGROUND:":[0],"Platinum-based":[1],"chemotherapy":[2],"with":[3,13,57,76,138,169,277,282,286],"or":[4,15,84,102,108,234,289],"without":[5],"bevacizumab":[6],"is":[7,33],"the":[8,21,87,292],"first-line":[9,29,88,293],"treatment":[10,22,220],"for":[11,26,99],"patients":[12,56,71,135,149,213,228,281],"recurrent":[14],"metastatic":[16],"cervical":[17,78],"cancer":[18,79],"(r/mCC),":[19],"and":[20,37,173,266],"options":[23],"are":[24],"limited":[25],"r/mCC":[27,285],"after":[28],"treatment.":[30],"Enlonstobart":[31],"(SG001)":[32],"a":[34,52,151,156],"fully":[35],"humanized":[36],"high-affinity":[38],"anti-PD-1":[39],"immunoglobulin":[40],"G4":[41],"monoclonal":[42],"antibody.":[43],"Previous":[44],"phase":[45,67],"Ib":[46],"study":[47,110],"demonstrated":[48,273],"that":[49],"SG001":[50,93,271],"had":[51,81,150,231],"promising":[53],"efficacy":[54],"in":[55,280],"PD-L1":[58,283],"positive":[59,284],"r/mCC.":[60],"METHODS:":[61],"In":[62],"this":[63],"multicenter,":[64],"single-arm,":[65],"open-label,":[66],"II":[68],"study,":[69],"eligible":[70],"were":[72,113,136,243],"\u2265":[73],"18":[74],"years":[75,143],"PD-L1-positive":[77],"who":[80],"progression":[82,196,287],"on":[83,288],"intolerance":[85,290],"to":[86,291],"platinum-based":[89,294],"chemotherapy.":[90,295],"Patients":[91],"received":[92],"240":[94],"mg":[95],"every":[96],"two":[97,170],"weeks":[98],"24":[100],"months":[101,161,190,201],"until":[103],"disease":[104,178],"progression,":[105],"intolerable":[106],"toxicities,":[107],"other":[109],"discontinuation":[111],"criteria":[112],"met.":[114],"The":[115,177,237],"primary":[116],"endpoint":[117],"was":[118,166,181,188,199,209],"confirmed":[119,164],"objective":[120],"response":[121,187],"rate":[122,180],"(ORR)":[123],"assessed":[124],"by":[125,129],"RECIST":[126],"version":[127],"1.1":[128],"independent":[130],"review":[131],"committee.":[132],"RESULTS:":[133],"107":[134],"enrolled":[137],"median":[139,157,195],"age":[140],"of":[141,148,153,159,186,225],"53":[142],"(range":[144,162],"26-72).":[145],"64.5":[146],"%":[147,192,203],"ECOG":[152],"1.":[154],"After":[155],"follow-up":[158],"14.0":[160],"0.4-21.9),":[163],"ORR":[165],"29.0":[167],"%,":[168],"complete":[171],"responses":[172],"twenty-nine":[174],"partial":[175],"responses.":[176],"control":[179],"54.2":[182],"%.":[183],"Median":[184,206],"duration":[185],"16.6":[189],"(95":[191,202],"CI":[193,204],"10.8-NA),":[194],"free":[197],"survival":[198,208],"3.1":[200],"2.2-6.9).":[205],"overall":[207],"not":[210],"reached.":[211],"104":[212],"(97.2":[214],"%)":[215,230],"experienced":[216],"at":[217],"least":[218],"one":[219],"emergent":[221],"adverse":[222,241],"events":[223,242],"TEAEs,":[224],"which":[226],"38":[227],"(35.5":[229],"grade":[232],"3":[233],"higher":[235],"TEAEs.":[236],"most":[238],"common":[239],"treatment-related":[240],"leukopenia":[244],"(19.6":[245],"%),":[246,251,254,259,262,265],"increased":[247,255],"aspartate":[248],"aminotransferase":[249,257],"(18.7":[250],"anemia":[252],"(17.8":[253],"alanine":[256],"(15.9":[258],"hypothyroidism":[260],"(15.0":[261,264],"neutropenia":[263],"hyperthyroidism":[267],"(11.2":[268],"%).":[269],"CONCLUSION:":[270],"monotherapy":[272],"durable":[274],"anti-tumor":[275],"activity":[276],"acceptable":[278],"safety":[279],"TRIAL":[296],"REGISTRATION:":[297],"ClinicalTrials.gov":[298],"(NCT04886700).":[299]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":6}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2024-10-23T00:00:00"}