{"id":"https://openalex.org/W4403554104","doi":"https://doi.org/10.1016/j.htct.2024.09.129","title":"ANEMIA HEMOL\u00cdTICA MICROANGIOP\u00c1TICA SECUND\u00c1RIA \u00c0 NEOPLASIA MAM\u00c1RIA METAST\u00c1TICA: UM DESAFIO DIAGN\u00d3STICO NA PR\u00c1TICA CL\u00cdNICA","display_name":"ANEMIA HEMOL\u00cdTICA MICROANGIOP\u00c1TICA SECUND\u00c1RIA \u00c0 NEOPLASIA MAM\u00c1RIA METAST\u00c1TICA: UM DESAFIO DIAGN\u00d3STICO NA PR\u00c1TICA CL\u00cdNICA","publication_year":2024,"publication_date":"2024-10-01","ids":{"openalex":"https://openalex.org/W4403554104","doi":"https://doi.org/10.1016/j.htct.2024.09.129"},"language":"pt","primary_location":{"id":"doi:10.1016/j.htct.2024.09.129","doi":"https://doi.org/10.1016/j.htct.2024.09.129","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.htct.2024.09.129","pdf_url":null,"source":{"id":"https://openalex.org/S2898598332","display_name":"Hematology Transfusion and Cell Therapy","issn_l":"2531-1379","issn":["2531-1379","2531-1387"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","poland-20","russia-white-list-3","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hematology, Transfusion and Cell Therapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.1016/j.htct.2024.09.129","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072045280","display_name":"Jos\u00e9 Vinicius Dos Santos","orcid":"https://orcid.org/0000-0001-6895-5936","observed_orcids":["https://orcid.org/0000-0001-6895-5936"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"JIOD Santos","raw_affiliation_strings":["Funda\u00e7\u00e3o de Hematologia e Hemoterapia de Pernambuco (HEMOPE), Recife, PE, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Funda\u00e7\u00e3o de Hematologia e Hemoterapia de Pernambuco (HEMOPE), Recife, PE, Brasil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029644134","display_name":"Marisa Lopes Lima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I25112270","display_name":"Universidade Federal de Pernambuco","ror":"https://ror.org/047908t24","country_code":"BR","type":"education","lineage":["https://openalex.org/I25112270"]},{"id":"https://openalex.org/I4210138879","display_name":"Hospital das Cl\u00ednicas da Universidade Federal de Pernambuco","ror":"https://ror.org/03rehvw54","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210138879"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"MCMC Lima","raw_affiliation_strings":["Hospital das Cl\u00ednicas, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital das Cl\u00ednicas, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brasil","institution_ids":["https://openalex.org/I25112270","https://openalex.org/I4210138879"]}]},{"author_position":"middle","author":{"id":null,"display_name":"LEL Leite","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"LEL Leite","raw_affiliation_strings":["Funda\u00e7\u00e3o de Hematologia e Hemoterapia de Pernambuco (HEMOPE), Recife, PE, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Funda\u00e7\u00e3o de Hematologia e Hemoterapia de Pernambuco (HEMOPE), Recife, PE, Brasil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114327835","display_name":"PBT Ernesto","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"PBT Ernesto","raw_affiliation_strings":["Funda\u00e7\u00e3o de Hematologia e Hemoterapia de Pernambuco (HEMOPE), Recife, PE, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Funda\u00e7\u00e3o de Hematologia e Hemoterapia de Pernambuco (HEMOPE), Recife, PE, Brasil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107770980","display_name":"RIN Rocha","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"RIN Rocha","raw_affiliation_strings":["Funda\u00e7\u00e3o de Hematologia e Hemoterapia de Pernambuco (HEMOPE), Recife, PE, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Funda\u00e7\u00e3o de Hematologia e Hemoterapia de Pernambuco (HEMOPE), Recife, PE, Brasil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113580395","display_name":"AS Guimar\u00e3es","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I25112270","display_name":"Universidade Federal de Pernambuco","ror":"https://ror.org/047908t24","country_code":"BR","type":"education","lineage":["https://openalex.org/I25112270"]},{"id":"https://openalex.org/I4210138879","display_name":"Hospital das Cl\u00ednicas da Universidade Federal de Pernambuco","ror":"https://ror.org/03rehvw54","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210138879"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"AS Guimar\u00e3es","raw_affiliation_strings":["Hospital das Cl\u00ednicas, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital das Cl\u00ednicas, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brasil","institution_ids":["https://openalex.org/I25112270","https://openalex.org/I4210138879"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087980614","display_name":"R. P. Brand\u00e3o","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I25112270","display_name":"Universidade Federal de Pernambuco","ror":"https://ror.org/047908t24","country_code":"BR","type":"education","lineage":["https://openalex.org/I25112270"]},{"id":"https://openalex.org/I4210138879","display_name":"Hospital das Cl\u00ednicas da Universidade Federal de Pernambuco","ror":"https://ror.org/03rehvw54","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210138879"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"RA Brand\u00e3o","raw_affiliation_strings":["Hospital das Cl\u00ednicas, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital das Cl\u00ednicas, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brasil","institution_ids":["https://openalex.org/I25112270","https://openalex.org/I4210138879"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110782456","display_name":"JO Vieira","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I25112270","display_name":"Universidade Federal de Pernambuco","ror":"https://ror.org/047908t24","country_code":"BR","type":"education","lineage":["https://openalex.org/I25112270"]},{"id":"https://openalex.org/I4210138879","display_name":"Hospital das Cl\u00ednicas da Universidade Federal de Pernambuco","ror":"https://ror.org/03rehvw54","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210138879"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"JO Vieira","raw_affiliation_strings":["Funda\u00e7\u00e3o de Hematologia e Hemoterapia de Pernambuco (HEMOPE), Recife, PE, Brasil","Hospital das Cl\u00ednicas, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Funda\u00e7\u00e3o de Hematologia e Hemoterapia de Pernambuco (HEMOPE), Recife, PE, Brasil","institution_ids":[]},{"raw_affiliation_string":"Hospital das Cl\u00ednicas, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brasil","institution_ids":["https://openalex.org/I25112270","https://openalex.org/I4210138879"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039673853","display_name":"C.G. Pires","orcid":"https://orcid.org/0000-0003-4075-1610","observed_orcids":["https://orcid.org/0000-0003-4075-1610"]},"institutions":[{"id":"https://openalex.org/I25112270","display_name":"Universidade Federal de Pernambuco","ror":"https://ror.org/047908t24","country_code":"BR","type":"education","lineage":["https://openalex.org/I25112270"]},{"id":"https://openalex.org/I4210138879","display_name":"Hospital das Cl\u00ednicas da Universidade Federal de Pernambuco","ror":"https://ror.org/03rehvw54","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210138879"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"CWBC Pires","raw_affiliation_strings":["Funda\u00e7\u00e3o de Hematologia e Hemoterapia de Pernambuco (HEMOPE), Recife, PE, Brasil","Hospital das Cl\u00ednicas, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Funda\u00e7\u00e3o de Hematologia e Hemoterapia de Pernambuco (HEMOPE), Recife, PE, Brasil","institution_ids":[]},{"raw_affiliation_string":"Hospital das Cl\u00ednicas, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brasil","institution_ids":["https://openalex.org/I25112270","https://openalex.org/I4210138879"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":0,"currency":"USD","value_usd":0},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.15441898,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"46","issue":null,"first_page":"S77","last_page":"S77"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":0.9735999703407288,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":0.9735999703407288,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12845","display_name":"Methemoglobinemia and Tumor Lysis Syndrome","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11660","display_name":"Blood groups and transfusion","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microangiopathic-hemolytic-anemia","display_name":"microangiopathic hemolytic anemia","score":0.9610000252723694},{"id":"https://openalex.org/keywords/thrombotic-thrombocytopenic-purpura","display_name":"thrombotic thrombocytopenic purpura","score":0.921999990940094},{"id":"https://openalex.org/keywords/metastatic-breast-cancer","display_name":"metastatic breast cancer","score":0.8460000157356262},{"id":"https://openalex.org/keywords/schistocytes","display_name":"schistocytes","score":0.6119999885559082},{"id":"https://openalex.org/keywords/reticulocytosis","display_name":"reticulocytosis","score":0.7459999918937683},{"id":"https://openalex.org/keywords/thrombocytopenia","display_name":"thrombocytopenia","score":0.7689999938011169},{"id":"https://openalex.org/keywords/hyperbilirubinemia","display_name":"hyperbilirubinemia","score":0.6110000014305115},{"id":"https://openalex.org/keywords/acute-kidney-injury","display_name":"acute kidney injury","score":0.5429999828338623},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.3799999952316284},{"id":"https://openalex.org/keywords/breast-cancer-recurrence","display_name":"breast cancer recurrence","score":0.38100001215934753},{"id":"https://openalex.org/keywords/chemotherapy-induced-thrombocytopenia","display_name":"chemotherapy-induced thrombocytopenia","score":0.4909999966621399}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8151246309280396},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4637160301208496}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/j.htct.2024.09.129","doi":"https://doi.org/10.1016/j.htct.2024.09.129","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.htct.2024.09.129","pdf_url":null,"source":{"id":"https://openalex.org/S2898598332","display_name":"Hematology Transfusion and Cell Therapy","issn_l":"2531-1379","issn":["2531-1379","2531-1387"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","poland-20","russia-white-list-3","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hematology, Transfusion and Cell Therapy","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:fd8e8cc51f2243be84d7567642052fd1","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/fd8e8cc51f2243be84d7567642052fd1","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Hematology, Transfusion and Cell Therapy, Vol 46, Iss , Pp S77- (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.htct.2024.09.129","doi":"https://doi.org/10.1016/j.htct.2024.09.129","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.htct.2024.09.129","pdf_url":null,"source":{"id":"https://openalex.org/S2898598332","display_name":"Hematology Transfusion and Cell Therapy","issn_l":"2531-1379","issn":["2531-1379","2531-1387"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","poland-20","russia-white-list-3","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hematology, Transfusion and Cell Therapy","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4403553942","https://openalex.org/W4306254492","https://openalex.org/W4403554096","https://openalex.org/W3207519437","https://openalex.org/W2409312837","https://openalex.org/W2404693571","https://openalex.org/W7160413779","https://openalex.org/W1991027491","https://openalex.org/W2087071088","https://openalex.org/W1920599462"],"abstract_inverted_index":{"A":[0,313],"anemia":[1,22],"hemol\u00edtica":[2,23],"microangiop\u00e1tica":[3,24],"(maha)":[4],"\u00e9":[5,370],"caracterizada":[6],"por":[7,372],"hem\u00f3lise":[8],"n\u00e3o":[9],"imune":[10],"em":[11,91,99,131],"decorr\u00eancia":[12],"do":[13],"cisalhamento":[14],"intravascular":[15],"dos":[16,303,338],"eritr\u00f3citos.":[17],"Discutir":[18],"um":[19,52],"caso":[20],"de":[21,39,47,59,70,72,97,123,129,135,162,195,211,243,247,268,276,289,296,308,343,347,368],"secund\u00e1ria":[25],"\u00e0":[26,78,318,321,352],"neoplasia":[27,71,354],"mam\u00e1ria":[28],"metast\u00e1tica":[29],"com":[30,34,45,55,101,103,121,137,199,221,256,271,283,300,340,358],"apresenta\u00e7\u00e3o":[31],"cl\u00ednico-laboratorial":[32],"compat\u00edvel":[33,282],"p\u00farpura":[35],"trombocitop\u00eanica":[36],"tromb\u00f3tica.":[37],"Paciente":[38,298],"51":[40],"anos,":[41],"sexo":[42],"feminino,":[43],"admitida":[44],"hist\u00f3ria":[46],"astenia":[48],"e":[49,62,80,84,106,127,165,197,204,209,234,273,291,331,377],"hiporexia":[50],"h\u00e1":[51,65],"m\u00eas,":[53],"evoluindo":[54],"lombalgia,":[56],"cefaleia":[57],"holocraniana":[58],"forte":[60],"intensidade":[61],"desorienta\u00e7\u00e3o":[63],"t\u00e8mporo-espacial":[64],"10":[66],"dias.":[67],"Antecedente":[68],"pessoal":[69],"mama":[73],"ductal":[74],"invasivo":[75],"(t3n1amx),":[76],"submetida":[77],"quadrantectomia":[79],"esvaziamento":[81],"axilar,":[82],"radioterapia":[83],"quimioterapia":[85,270],"(adriblastina/ciclofosfamida/docetaxel/paclitaxel)":[86],"+":[87,151,154,157],"hormonioterapia":[88],"(tamoxifeno/anastrazol).":[89],"Permanecia":[90],"acompanhamento":[92],"oncol\u00f3gico":[93],"regular,":[94],"sem":[95,108,213],"evid\u00eancia":[96],"doen\u00e7a":[98,332],"atividade,":[100],"reestadiamento":[102],"cintilografia":[104],"\u00f3ssea":[105,278],"mamografia":[107],"altera\u00e7\u00f5es":[109],"no":[110,249,375],"\u00faltimo":[111],"ano.":[112],"\u00c0":[113],"admiss\u00e3o,":[114,219],"encontrava-se":[115],"hipocorada":[116],"(+/4+),":[117,119],"ict\u00e9rica":[118],"desorientada,":[120],"lentifica\u00e7\u00e3o":[122],"fala,":[124],"instabilidade":[125],"postural":[126],"diminui\u00e7\u00e3o":[128],"for\u00e7a":[130],"membros":[132],"inferiores.":[133],"Laborat\u00f3rio":[134],"admiss\u00e3o":[136],"hb:":[138,225],"8,5":[139],"g%":[140,227],"(vcm:":[141,228],"91":[142],"fl;":[143,230],"hcm:":[144,231],"30.6":[145],"pg;":[146],"rdw:":[147],"24%.":[148],"Com":[149],"policromasia":[150],"numerosos":[152],"esquiz\u00f3citos":[153],"pontilhado":[155],"bas\u00f3filo":[156],"60":[158],"eritroblastos/100":[159],"gb),":[160],"leuc\u00f3citos":[161],"9630/mm":[163],"3":[164,168,238],"plaquetopenia":[166],"(31.000/mm":[167],");":[169],"reticul\u00f3citos:":[170],"9,9%":[171],"(219.000/uL);":[172],"creatinina:":[173],"0,8":[174],"mg/dL;":[175],"bilirrubina":[176],"total:":[177],"2,95":[178],"mg/dL":[179],"(indireta:":[180],"2,44":[181],"mg/dL);":[182],"tgo:":[183],"197":[184],"u/L;":[185,188,191],"tgp:":[186],"74":[187],"dhl:":[189],"2382":[190],"inr:":[192],"1,2,":[193],"tomografias":[194],"t\u00f3rax":[196],"abdome":[198],"moderado":[200],"derrame":[201],"pleural":[202],"bilateral":[203],"m\u00faltiplas":[205],"les\u00f5es":[206],"osteol\u00edticas":[207],"difusas":[208],"tomografia":[210],"cr\u00e2nio":[212],"altera\u00e7\u00f5es.":[214],"Quatro":[215],"dias":[216],"ap\u00f3s":[217],"a":[218,287,366],"evoluiu":[220,299],"piora":[222],"da":[223,334],"bicitopenia:":[224],"5.2":[226],"86":[229],"33,5":[232],"pg)":[233],"pqt:":[235],"16.000":[236],"/mm":[237],".":[239],"Escore":[240],"plasmic":[241],"calculado":[242],"06":[244],"pontos":[245],"(indisponibilidade":[246],"adamts13":[248],"servi\u00e7o).":[250],"Iniciado":[251],"plasma":[252],"fresco":[253],"congelado,":[254],"pulsoterapia":[255],"metilprednisolona":[257],"500":[258],"mg/dia":[259],"(programados":[260],"03":[261],"dias),":[262],"solicitado":[263],"plasmaf\u00e9rese":[264,290],"terap\u00eautica":[265],"ao":[266,362],"servi\u00e7o":[267],"apoio,":[269],"paclitaxel":[272],"realizada":[274],"bi\u00f3psia":[275],"medula":[277],"cujo":[279],"resultado":[280],"foi":[281],"adenocarcinoma":[284],"metast\u00e1tico.":[285],"Suspensa":[286],"indica\u00e7\u00e3o":[288],"mantido":[292],"o":[293,345],"tratamento":[294,363],"quimioter\u00e1pico":[295],"resgate.":[297],"melhora":[301],"completa":[302],"sintomas,":[304],"bem":[305],"como":[306],"normaliza\u00e7\u00e3o":[307],"todos":[309],"os":[310],"par\u00e2metros":[311],"hematol\u00f3gicos.":[312],"maha":[314,348],"frequentemente":[315],"est\u00e1":[316],"associada":[317],"ptt":[319],"ou":[320,361],"s\u00edndrome":[322],"hemol\u00edtico-ur\u00eamica.":[323],"Dentre":[324],"outras":[325],"causas":[326],"destacam-se":[327],"entidades":[328],"neopl\u00e1sicas,":[329],"infec\u00e7\u00f5es":[330],"hipertensiva":[333],"gesta\u00e7\u00e3o.":[335],"Nos":[336],"casos":[337],"pacientes":[339],"diagn\u00f3stico":[341],"pr\u00e9vio":[342],"neoplasias,":[344],"desenvolvimento":[346],"pode":[349],"estar":[350],"associado":[351],"pr\u00f3pria":[353],"(principalmente":[355],"nos":[356],"adenocarcinomas":[357],"met\u00e1stase":[359],"medular)":[360],"quimioter\u00e1pico.":[364],"Diferenciar":[365],"etiologia":[367],"base":[369],"importante":[371],"impactar":[373],"diretamente":[374],"progn\u00f3stico":[376],"nas":[378],"estrat\u00e9gias":[379],"terap\u00eauticas":[380],"dispon\u00edveis.":[381]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2024-10-19T00:00:00"}