{"id":"https://openalex.org/W4403548851","doi":"https://doi.org/10.1080/09638288.2024.2415328","title":"Effect of serious games over conventional therapy in the rehabilitation of people with multiple sclerosis \u2013 a systematic review and meta-analysis","display_name":"Effect of serious games over conventional therapy in the rehabilitation of people with multiple sclerosis \u2013 a systematic review and meta-analysis","publication_year":2024,"publication_date":"2024-10-18","ids":{"openalex":"https://openalex.org/W4403548851","doi":"https://doi.org/10.1080/09638288.2024.2415328","pmid":"https://pubmed.ncbi.nlm.nih.gov/39421950"},"language":"en","primary_location":{"id":"doi:10.1080/09638288.2024.2415328","doi":"https://doi.org/10.1080/09638288.2024.2415328","is_oa":false,"landing_page_url":"https://doi.org/10.1080/09638288.2024.2415328","pdf_url":null,"source":{"id":"https://openalex.org/S12843020","display_name":"Disability and Rehabilitation","issn_l":"0963-8288","issn":["0963-8288","1464-5165"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Disability and Rehabilitation","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/2078.1/292705","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089839704","display_name":"Ita Daryanti Saragih","orcid":"https://orcid.org/0000-0002-7177-5933","observed_orcids":["https://orcid.org/0000-0002-7177-5933"]},"institutions":[{"id":"https://openalex.org/I152743029","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96","country_code":"TW","type":"education","lineage":["https://openalex.org/I152743029"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Ita Daryanti Saragih","raw_affiliation_strings":["College of Nursing, Kaohsiung Medical University","College of Nursing, Kaohsiung Medical University, Kaohsiung, Taiwan"],"raw_orcid":"https://orcid.org/0000-0002-7177-5933","affiliations":[{"raw_affiliation_string":"College of Nursing, Kaohsiung Medical University","institution_ids":["https://openalex.org/I152743029"]},{"raw_affiliation_string":"College of Nursing, Kaohsiung Medical University, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114325691","display_name":"Willy Gervais","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405282791","display_name":"H\u00f4pital La Musse","ror":"https://ror.org/00ezzh492","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4405282791"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Willy Gervais","raw_affiliation_strings":["Institut de formation en masso-kin\u00e9sith\u00e9rapie La Musse","Institut de formation en masso-kin\u00e9sith\u00e9rapie La Musse, Saint S\u00e9bastien de Morsent, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de formation en masso-kin\u00e9sith\u00e9rapie La Musse","institution_ids":["https://openalex.org/I4405282791"]},{"raw_affiliation_string":"Institut de formation en masso-kin\u00e9sith\u00e9rapie La Musse, Saint S\u00e9bastien de Morsent, France","institution_ids":["https://openalex.org/I4405282791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092150380","display_name":"Jean-Philippe Lamora","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405282791","display_name":"H\u00f4pital La Musse","ror":"https://ror.org/00ezzh492","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4405282791"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-Philippe Lamora","raw_affiliation_strings":["Institut de formation en masso-kin\u00e9sith\u00e9rapie La Musse","Institut de formation en masso-kin\u00e9sith\u00e9rapie La Musse, Saint S\u00e9bastien de Morsent, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de formation en masso-kin\u00e9sith\u00e9rapie La Musse","institution_ids":["https://openalex.org/I4405282791"]},{"raw_affiliation_string":"Institut de formation en masso-kin\u00e9sith\u00e9rapie La Musse, Saint S\u00e9bastien de Morsent, France","institution_ids":["https://openalex.org/I4405282791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031510852","display_name":"Charles S\u00e8biyo Batcho","orcid":"https://orcid.org/0000-0003-1069-8556","observed_orcids":["https://orcid.org/0000-0003-1069-8556"]},"institutions":[{"id":"https://openalex.org/I43406934","display_name":"Universit\u00e9 Laval","ror":"https://ror.org/04sjchr03","country_code":"CA","type":"education","lineage":["https://openalex.org/I43406934"]},{"id":"https://openalex.org/I4405279799","display_name":"Centre interdisciplinaire de recherche en r\u00e9adaptation et int\u00e9gration sociale","ror":"https://ror.org/0214hkz02","country_code":"CA","type":"facility","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4392738268","https://openalex.org/I4405279799","https://openalex.org/I4405279980"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Charles Sebiyo Batcho","raw_affiliation_strings":["Centre interdisciplinaire de recherche en r\u00e9adaptation et int\u00e9gration sociale, Universit\u00e9 Laval","Department of rehabilitation, Faculty of medicine, Laval University","Centre interdisciplinaire de recherche en r\u00e9adaptation et int\u00e9gration sociale, Universit\u00e9 Laval, Qu\u00e9bec, Canada","Department of rehabilitation, Faculty of medicine, Laval University, Quebec, QC, Canada"],"raw_orcid":"https://orcid.org/0000-0003-1069-8556","affiliations":[{"raw_affiliation_string":"Centre interdisciplinaire de recherche en r\u00e9adaptation et int\u00e9gration sociale, Universit\u00e9 Laval","institution_ids":["https://openalex.org/I43406934","https://openalex.org/I4405279799"]},{"raw_affiliation_string":"Department of rehabilitation, Faculty of medicine, Laval University","institution_ids":["https://openalex.org/I43406934"]},{"raw_affiliation_string":"Centre interdisciplinaire de recherche en r\u00e9adaptation et int\u00e9gration sociale, Universit\u00e9 Laval, Qu\u00e9bec, Canada","institution_ids":["https://openalex.org/I43406934","https://openalex.org/I4405279799"]},{"raw_affiliation_string":"Department of rehabilitation, Faculty of medicine, Laval University, Quebec, QC, Canada","institution_ids":["https://openalex.org/I43406934"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033759783","display_name":"Gauthier J. Everard","orcid":"https://orcid.org/0000-0001-5029-5693","observed_orcids":["https://orcid.org/0000-0001-5029-5693"]},"institutions":[{"id":"https://openalex.org/I43406934","display_name":"Universit\u00e9 Laval","ror":"https://ror.org/04sjchr03","country_code":"CA","type":"education","lineage":["https://openalex.org/I43406934"]},{"id":"https://openalex.org/I4405279799","display_name":"Centre interdisciplinaire de recherche en r\u00e9adaptation et int\u00e9gration sociale","ror":"https://ror.org/0214hkz02","country_code":"CA","type":"facility","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4392738268","https://openalex.org/I4405279799","https://openalex.org/I4405279980"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Gauthier Everard","raw_affiliation_strings":["Centre interdisciplinaire de recherche en r\u00e9adaptation et int\u00e9gration sociale, Universit\u00e9 Laval","Department of rehabilitation, Faculty of medicine, Laval University","Institut de Recherche Exp\u00e9rimentale et Clinique, Neuro Musculo Skeletal Lab (NMSK)","Centre interdisciplinaire de recherche en r\u00e9adaptation et int\u00e9gration sociale, Universit\u00e9 Laval, Qu\u00e9bec, Canada","Department of rehabilitation, Faculty of medicine, Laval University, Quebec, QC, Canada","Institut de Recherche Exp\u00e9rimentale et Clinique, Neuro Musculo Skeletal Lab (NMSK), Bruxelles, Belgium"],"raw_orcid":"https://orcid.org/0000-0001-5029-5693","affiliations":[{"raw_affiliation_string":"Centre interdisciplinaire de recherche en r\u00e9adaptation et int\u00e9gration sociale, Universit\u00e9 Laval","institution_ids":["https://openalex.org/I43406934","https://openalex.org/I4405279799"]},{"raw_affiliation_string":"Department of rehabilitation, Faculty of medicine, Laval University","institution_ids":["https://openalex.org/I43406934"]},{"raw_affiliation_string":"Institut de Recherche Exp\u00e9rimentale et Clinique, Neuro Musculo Skeletal Lab (NMSK)","institution_ids":[]},{"raw_affiliation_string":"Centre interdisciplinaire de recherche en r\u00e9adaptation et int\u00e9gration sociale, Universit\u00e9 Laval, Qu\u00e9bec, Canada","institution_ids":["https://openalex.org/I43406934","https://openalex.org/I4405279799"]},{"raw_affiliation_string":"Department of rehabilitation, Faculty of medicine, Laval University, Quebec, QC, Canada","institution_ids":["https://openalex.org/I43406934"]},{"raw_affiliation_string":"Institut de Recherche Exp\u00e9rimentale et Clinique, Neuro Musculo Skeletal Lab (NMSK), Bruxelles, Belgium","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5033759783"],"corresponding_institution_ids":["https://openalex.org/I43406934","https://openalex.org/I4405279799"],"apc_list":null,"apc_paid":null,"fwci":0.4607,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.42750986,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"47","issue":"13","first_page":"3224","last_page":"3244"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.6338000297546387,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.6338000297546387,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10510","display_name":"Stroke Rehabilitation and Recovery","score":0.31150001287460327,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10114","display_name":"Balance, Gait, and Falls Prevention","score":0.01140000019222498,"subfield":{"id":"https://openalex.org/subfields/3612","display_name":"Physical Therapy, Sports Therapy and Rehabilitation"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/serious-games","display_name":"serious games","score":0.9580000042915344},{"id":"https://openalex.org/keywords/multiple-sclerosis","display_name":"multiple sclerosis","score":0.8840000033378601},{"id":"https://openalex.org/keywords/virtual-reality","display_name":"virtual reality","score":0.7210000157356262},{"id":"https://openalex.org/keywords/rehabilitation","display_name":"rehabilitation","score":0.6480000019073486},{"id":"https://openalex.org/keywords/upper-limb-activity","display_name":"upper limb activity","score":0.7170000076293945},{"id":"https://openalex.org/keywords/balance","display_name":"balance","score":0.9900000095367432},{"id":"https://openalex.org/keywords/gait","display_name":"gait","score":1.0},{"id":"https://openalex.org/keywords/fatigue","display_name":"fatigue","score":0.996999979019165},{"id":"https://openalex.org/keywords/cognitive-function","display_name":"cognitive function","score":0.8740000128746033},{"id":"https://openalex.org/keywords/visuospatial-memory","display_name":"visuospatial memory","score":0.9380000233650208},{"id":"https://openalex.org/keywords/verbal-memory","display_name":"verbal memory","score":0.6549999713897705},{"id":"https://openalex.org/keywords/attention","display_name":"attention","score":0.6449999809265137},{"id":"https://openalex.org/keywords/semi-immersive-virtual-reality","display_name":"semi-immersive virtual reality","score":0.9200000166893005}],"concepts":[{"id":"https://openalex.org/C2778818304","wikidata":"https://www.wikidata.org/wiki/Q1819478","display_name":"Rehabilitation","level":2,"score":0.7487856149673462},{"id":"https://openalex.org/C2780640218","wikidata":"https://www.wikidata.org/wiki/Q8277","display_name":"Multiple sclerosis","level":2,"score":0.6989536881446838},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.6398316621780396},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.5616811513900757},{"id":"https://openalex.org/C189708586","wikidata":"https://www.wikidata.org/wiki/Q1504425","display_name":"Systematic review","level":3,"score":0.4830387532711029},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.459812730550766},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.4109148681163788},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40397322177886963},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.3531479835510254},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.15974396467208862},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.07379662990570068},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000076142","descriptor_name":"Virtual Reality","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004856","descriptor_name":"Postural Balance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005221","descriptor_name":"Fatigue","qualifier_ui":"Q000534","qualifier_name":"rehabilitation","is_major_topic":false},{"descriptor_ui":"D005684","descriptor_name":"Gait","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009103","descriptor_name":"Multiple Sclerosis","qualifier_ui":"Q000534","qualifier_name":"rehabilitation","is_major_topic":true},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018910","descriptor_name":"Video Games","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D034941","descriptor_name":"Upper Extremity","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1080/09638288.2024.2415328","doi":"https://doi.org/10.1080/09638288.2024.2415328","is_oa":false,"landing_page_url":"https://doi.org/10.1080/09638288.2024.2415328","pdf_url":null,"source":{"id":"https://openalex.org/S12843020","display_name":"Disability and Rehabilitation","issn_l":"0963-8288","issn":["0963-8288","1464-5165"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Disability and Rehabilitation","raw_type":"journal-article"},{"id":"pmid:39421950","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39421950","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Disability and rehabilitation","raw_type":"Journal Article"},{"id":"pmh:oai:dial.uclouvain.be:boreal:292705","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2078.1/292705","pdf_url":null,"source":{"id":"https://openalex.org/S4306401902","display_name":"Digital Access to Libraries (Universit\u00e9 catholique de Louvain (UCL), l'Universit\u00e9 de Namur (UNamur) and the Universit\u00e9 Saint-Louis (USL-B))","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I95674353","host_organization_name":"UCLouvain","host_organization_lineage":["https://openalex.org/I95674353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Disability and rehabilitation, Vol. 47, no. 13, p. 3224-3244 (2025)","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:dial.uclouvain.be:boreal:292705","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2078.1/292705","pdf_url":null,"source":{"id":"https://openalex.org/S4306401902","display_name":"Digital Access to Libraries (Universit\u00e9 catholique de Louvain (UCL), l'Universit\u00e9 de Namur (UNamur) and the Universit\u00e9 Saint-Louis (USL-B))","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I95674353","host_organization_name":"UCLouvain","host_organization_lineage":["https://openalex.org/I95674353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Disability and rehabilitation, Vol. 47, no. 13, p. 3224-3244 (2025)","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320329072","display_name":"R\u00e9seau Provincial de Recherche en Adaptation-R\u00e9adaptation","ror":"https://ror.org/033janr42"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":106,"referenced_works":["https://openalex.org/W1556965042","https://openalex.org/W1948338320","https://openalex.org/W1977086599","https://openalex.org/W1979404848","https://openalex.org/W1982234270","https://openalex.org/W1992436652","https://openalex.org/W1994058370","https://openalex.org/W1996858578","https://openalex.org/W2001379338","https://openalex.org/W2005110420","https://openalex.org/W2006883454","https://openalex.org/W2012724478","https://openalex.org/W2013999515","https://openalex.org/W2017430639","https://openalex.org/W2017658548","https://openalex.org/W2023842766","https://openalex.org/W2027508848","https://openalex.org/W2040546489","https://openalex.org/W2052092949","https://openalex.org/W2059815658","https://openalex.org/W2059991128","https://openalex.org/W2070003162","https://openalex.org/W2079124738","https://openalex.org/W2086956630","https://openalex.org/W2095665209","https://openalex.org/W2097573856","https://openalex.org/W2110499279","https://openalex.org/W2112165124","https://openalex.org/W2114242035","https://openalex.org/W2118652077","https://openalex.org/W2119526403","https://openalex.org/W2124215468","https://openalex.org/W2139466644","https://openalex.org/W2155058845","https://openalex.org/W2157823046","https://openalex.org/W2159018172","https://openalex.org/W2163116676","https://openalex.org/W2167980591","https://openalex.org/W2170892587","https://openalex.org/W2291981771","https://openalex.org/W2404579350","https://openalex.org/W2548469050","https://openalex.org/W2588292672","https://openalex.org/W2589005373","https://openalex.org/W2597911360","https://openalex.org/W2624103370","https://openalex.org/W2624144577","https://openalex.org/W2734616065","https://openalex.org/W2750599034","https://openalex.org/W2777074421","https://openalex.org/W2784859886","https://openalex.org/W2794532029","https://openalex.org/W2796578616","https://openalex.org/W2801573807","https://openalex.org/W2802863958","https://openalex.org/W2893184825","https://openalex.org/W2894567542","https://openalex.org/W2898999215","https://openalex.org/W2901140528","https://openalex.org/W2910591596","https://openalex.org/W2911343483","https://openalex.org/W2914871332","https://openalex.org/W2949105720","https://openalex.org/W2970684805","https://openalex.org/W2984542815","https://openalex.org/W2989727564","https://openalex.org/W2995589565","https://openalex.org/W2999337757","https://openalex.org/W3003109000","https://openalex.org/W3009520586","https://openalex.org/W3023487080","https://openalex.org/W3032925303","https://openalex.org/W3084573305","https://openalex.org/W3084818633","https://openalex.org/W3089264828","https://openalex.org/W3097128274","https://openalex.org/W3099273656","https://openalex.org/W3111048040","https://openalex.org/W3116155986","https://openalex.org/W3118615836","https://openalex.org/W3125666830","https://openalex.org/W3139948499","https://openalex.org/W3150635113","https://openalex.org/W3165109500","https://openalex.org/W3173029564","https://openalex.org/W3177999567","https://openalex.org/W3182966340","https://openalex.org/W3185920825","https://openalex.org/W3207905363","https://openalex.org/W3213559501","https://openalex.org/W3217593975","https://openalex.org/W4200094050","https://openalex.org/W4210911928","https://openalex.org/W4211042806","https://openalex.org/W4281762118","https://openalex.org/W4289951895","https://openalex.org/W4299627282","https://openalex.org/W4308558934","https://openalex.org/W4308773337","https://openalex.org/W4309374135","https://openalex.org/W4312106188","https://openalex.org/W4384407716","https://openalex.org/W4385999549","https://openalex.org/W4389049818","https://openalex.org/W4390345192","https://openalex.org/W4401155919"],"related_works":["https://openalex.org/W2964272047","https://openalex.org/W3023487080","https://openalex.org/W2765882974","https://openalex.org/W2982256405","https://openalex.org/W2885109744","https://openalex.org/W4389892986","https://openalex.org/W4200094050","https://openalex.org/W4392185157","https://openalex.org/W4390919635","https://openalex.org/W4389092557"],"abstract_inverted_index":{"Purpose":[0],"This":[1,174],"meta-analysis":[2],"aimed":[3],"to":[4,128],"quantify":[5],"the":[6,51,61],"effect":[7,111,198],"of":[8,54,181],"serious":[9,58,108,135,147,165,187],"games":[10,109,136,148,166,188],"over":[11],"conventional":[12,65],"therapy":[13],"on":[14,112,199],"upper-limb":[15],"activity,":[16,71,115,202],"balance,":[17,72,191],"gait,":[18,73,116,203],"fatigue,":[19,74],"and":[20,28,39,78,121,156,193,204],"cognitive":[21,76,164,206],"functions":[22,126,207],"in":[23],"people":[24],"with":[25,48,93,177],"multiple":[26,49],"sclerosis.Materials":[27],"methods":[29],"Search":[30],"strategies":[31],"were":[32,42,46,86,102],"developed":[33],"for":[34],"PubMed,":[35],"Embase,":[36],"Cochrane":[37],"Library,":[38],"Scopus.":[40],"Studies":[41],"selected":[43,103],"if":[44],"participants":[45],"adults":[47],"sclerosis;":[50],"intervention":[52],"consisted":[53],"a":[55,80,89,94,178],"virtual":[56,133,161],"reality":[57,134,162],"game-based":[59],"program;":[60],"control":[62],"group":[63],"received":[64],"therapy;":[66],"outcomes":[67],"included":[68],"upper":[69,113,200],"limb":[70,114,201],"or":[75],"functions;":[77],"used":[79],"randomized":[81],"controlled":[82],"trial":[83],"design.":[84],"Data":[85],"synthesized":[87],"using":[88],"standardized":[90],"mean":[91],"difference":[92],"random-effects":[95],"model.Results":[96],"From":[97],"2532":[98],"studies,":[99],"seventeen":[100],"trials":[101],"(n":[104],"=":[105,138,140,142,150,152,168,170,172],"740).":[106],"Overall,":[107],"programs":[110],"verbal":[117,119],"memory,":[118,195],"fluency":[120],"attention":[122],"seemed":[123],"neutral.":[124,209],"Balance":[125],"appeared":[127],"be":[129],"improved":[130],"by":[131,145,159],"semi-immersive":[132,160],"(SMD":[137,149,167],"0.48;95%CI":[139],"0.12\u20130.84;p":[141],"0.01;I2=0%),":[143],"fatigue":[144,192],"treadmill":[146],"0.80;95%CI":[151],"0.40\u20131.20;p":[153],"<":[154],"0.001)":[155],"visuo-spatial":[157,194],"memory":[158],"general":[163],"0.35;95%CI":[169],"0.04\u20130.65;p":[171],"0.03;I2=0%).Conclusion":[173],"review":[175],"suggests,":[176],"very-low-to-low":[179],"certainty":[180],"evidence,":[182],"that":[183],"while":[184],"some":[185],"specific":[186],"may":[189],"improve":[190],"their":[196],"overall":[197],"other":[205],"appears":[208]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2024-10-19T00:00:00"}