{"id":"https://openalex.org/W4403545208","doi":"https://doi.org/10.3390/ph17101393","title":"Protective Effects of Annona Atemoya Extracts on Inflammation, Oxidative Stress, and Renal Function in Cadmium-Induced Nephrotoxicity in Wistar Rats","display_name":"Protective Effects of Annona Atemoya Extracts on Inflammation, Oxidative Stress, and Renal Function in Cadmium-Induced Nephrotoxicity in Wistar Rats","publication_year":2024,"publication_date":"2024-10-18","ids":{"openalex":"https://openalex.org/W4403545208","doi":"https://doi.org/10.3390/ph17101393","pmid":"https://pubmed.ncbi.nlm.nih.gov/39459032","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11510283"},"language":"en","primary_location":{"id":"doi:10.3390/ph17101393","doi":"https://doi.org/10.3390/ph17101393","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ph17101393","pdf_url":"https://www.mdpi.com/1424-8247/17/10/1393/pdf?version=1729248067","source":{"id":"https://openalex.org/S16322639","display_name":"Pharmaceuticals","issn_l":"1424-8247","issn":["1424-8247"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceuticals","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8247/17/10/1393/pdf?version=1729248067","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028201704","display_name":"Alexandre Coelho Serquiz","orcid":"https://orcid.org/0000-0002-1345-9705","observed_orcids":["https://orcid.org/0000-0002-1345-9705"]},"institutions":[{"id":"https://openalex.org/I169045520","display_name":"Universidade Federal da Para\u00edba","ror":"https://ror.org/00p9vpz11","country_code":"BR","type":"education","lineage":["https://openalex.org/I169045520"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Alexandre Coelho Serquiz","raw_affiliation_strings":["Department of Nutrition, Health Sciences Center, Federal University of Para\u00edba, Jo\u00e3o Pessoa 58051-900, PS, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-1345-9705","affiliations":[{"raw_affiliation_string":"Department of Nutrition, Health Sciences Center, Federal University of Para\u00edba, Jo\u00e3o Pessoa 58051-900, PS, Brazil","institution_ids":["https://openalex.org/I169045520"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Joana de Angelis da Costa Barros Gomes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I35046152","display_name":"Universidade Federal do Rio Grande do Norte","ror":"https://ror.org/04wn09761","country_code":"BR","type":"education","lineage":["https://openalex.org/I35046152"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Joana de Angelis da Costa Barros Gomes","raw_affiliation_strings":["Laboratory of Biotechnology of Natural Polymers (BIOPOL), Graduate Program of Biochemistry and Molecular Biology, Bioscience Center, Federal University of Rio Grande do Norte\u2014UFRN, Natal 59078-970, RN, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biotechnology of Natural Polymers (BIOPOL), Graduate Program of Biochemistry and Molecular Biology, Bioscience Center, Federal University of Rio Grande do Norte\u2014UFRN, Natal 59078-970, RN, Brazil","institution_ids":["https://openalex.org/I35046152"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040494672","display_name":"Naisandra Bezerra da Silva Farias","orcid":"https://orcid.org/0000-0003-0828-109X","observed_orcids":["https://orcid.org/0000-0003-0828-109X","https://orcid.org/0000-0002-4468-2678"]},"institutions":[{"id":"https://openalex.org/I35046152","display_name":"Universidade Federal do Rio Grande do Norte","ror":"https://ror.org/04wn09761","country_code":"BR","type":"education","lineage":["https://openalex.org/I35046152"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Naisandra Bezerra da Silva Farias","raw_affiliation_strings":["Laboratory of Biotechnology of Natural Polymers (BIOPOL), Graduate Program of Biochemistry and Molecular Biology, Bioscience Center, Federal University of Rio Grande do Norte\u2014UFRN, Natal 59078-970, RN, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biotechnology of Natural Polymers (BIOPOL), Graduate Program of Biochemistry and Molecular Biology, Bioscience Center, Federal University of Rio Grande do Norte\u2014UFRN, Natal 59078-970, RN, Brazil","institution_ids":["https://openalex.org/I35046152"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036474175","display_name":"Denise Mafra","orcid":"https://orcid.org/0000-0001-6752-6056","observed_orcids":["https://orcid.org/0000-0001-6752-6056"]},"institutions":[{"id":"https://openalex.org/I122140584","display_name":"Universidade Federal do Rio de Janeiro","ror":"https://ror.org/03490as77","country_code":"BR","type":"education","lineage":["https://openalex.org/I122140584"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Denise Mafra","raw_affiliation_strings":["Graduate Program in Biological Sciences\u2014Physiology, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, RJ, Brazil"],"raw_orcid":"https://orcid.org/0000-0001-6752-6056","affiliations":[{"raw_affiliation_string":"Graduate Program in Biological Sciences\u2014Physiology, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 21941-902, RJ, Brazil","institution_ids":["https://openalex.org/I122140584"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Pietra Maria Pereira de Lima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I169045520","display_name":"Universidade Federal da Para\u00edba","ror":"https://ror.org/00p9vpz11","country_code":"BR","type":"education","lineage":["https://openalex.org/I169045520"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Pietra Maria Pereira de Lima","raw_affiliation_strings":["Department of Nutrition, Health Sciences Center, Federal University of Para\u00edba, Jo\u00e3o Pessoa 58051-900, PS, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition, Health Sciences Center, Federal University of Para\u00edba, Jo\u00e3o Pessoa 58051-900, PS, Brazil","institution_ids":["https://openalex.org/I169045520"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031655664","display_name":"Daniella de Oliveira Coutinho","orcid":"https://orcid.org/0009-0002-0375-8389","observed_orcids":["https://orcid.org/0009-0002-0375-8389"]},"institutions":[{"id":"https://openalex.org/I169045520","display_name":"Universidade Federal da Para\u00edba","ror":"https://ror.org/00p9vpz11","country_code":"BR","type":"education","lineage":["https://openalex.org/I169045520"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Daniella de Oliveira Coutinho","raw_affiliation_strings":["Department of Nutrition, Health Sciences Center, Federal University of Para\u00edba, Jo\u00e3o Pessoa 58051-900, PS, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition, Health Sciences Center, Federal University of Para\u00edba, Jo\u00e3o Pessoa 58051-900, PS, Brazil","institution_ids":["https://openalex.org/I169045520"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003101838","display_name":"Fernanda Priscila Barbosa Ribeiro","orcid":"https://orcid.org/0009-0004-3411-2884","observed_orcids":["https://orcid.org/0009-0004-3411-2884"]},"institutions":[{"id":"https://openalex.org/I169045520","display_name":"Universidade Federal da Para\u00edba","ror":"https://ror.org/00p9vpz11","country_code":"BR","type":"education","lineage":["https://openalex.org/I169045520"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Fernanda Priscila Barbosa Ribeiro","raw_affiliation_strings":["Department of Nutrition, Health Sciences Center, Federal University of Para\u00edba, Jo\u00e3o Pessoa 58051-900, PS, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition, Health Sciences Center, Federal University of Para\u00edba, Jo\u00e3o Pessoa 58051-900, PS, Brazil","institution_ids":["https://openalex.org/I169045520"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068873111","display_name":"Hugo Alexandre Oliveira Rocha","orcid":"https://orcid.org/0000-0003-2252-1221","observed_orcids":["https://orcid.org/0000-0003-2252-1221"]},"institutions":[{"id":"https://openalex.org/I35046152","display_name":"Universidade Federal do Rio Grande do Norte","ror":"https://ror.org/04wn09761","country_code":"BR","type":"education","lineage":["https://openalex.org/I35046152"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Hugo Alexandre de Oliveira Rocha","raw_affiliation_strings":["Laboratory of Biotechnology of Natural Polymers (BIOPOL), Graduate Program of Biochemistry and Molecular Biology, Bioscience Center, Federal University of Rio Grande do Norte\u2014UFRN, Natal 59078-970, RN, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biotechnology of Natural Polymers (BIOPOL), Graduate Program of Biochemistry and Molecular Biology, Bioscience Center, Federal University of Rio Grande do Norte\u2014UFRN, Natal 59078-970, RN, Brazil","institution_ids":["https://openalex.org/I35046152"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005613475","display_name":"Jos\u00e9 Luiz de Brito Alves","orcid":"https://orcid.org/0000-0003-4696-3809","observed_orcids":["https://orcid.org/0000-0003-4696-3809"]},"institutions":[{"id":"https://openalex.org/I169045520","display_name":"Universidade Federal da Para\u00edba","ror":"https://ror.org/00p9vpz11","country_code":"BR","type":"education","lineage":["https://openalex.org/I169045520"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Jos\u00e9 Luiz de Brito Alves","raw_affiliation_strings":["Department of Nutrition, Health Sciences Center, Federal University of Para\u00edba, Jo\u00e3o Pessoa 58051-900, PS, Brazil"],"raw_orcid":"https://orcid.org/0000-0003-4696-3809","affiliations":[{"raw_affiliation_string":"Department of Nutrition, Health Sciences Center, Federal University of Para\u00edba, Jo\u00e3o Pessoa 58051-900, PS, Brazil","institution_ids":["https://openalex.org/I169045520"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5005613475"],"corresponding_institution_ids":["https://openalex.org/I169045520"],"apc_list":{"value":2900,"currency":"CHF","value_usd":3296},"apc_paid":{"value":2900,"currency":"CHF","value_usd":3296},"fwci":0.7873,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.59764687,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":96},"biblio":{"volume":"17","issue":"10","first_page":"1393","last_page":"1393"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12497","display_name":"Traditional and Medicinal Uses of Annonaceae","score":0.004800000227987766,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12429","display_name":"Chemotherapy-induced organ toxicity mitigation","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/annona-atemoya","display_name":"Annona atemoya","score":0.9300000071525574},{"id":"https://openalex.org/keywords/heavy-metal-toxicity","display_name":"heavy metal toxicity","score":0.7279999852180481},{"id":"https://openalex.org/keywords/renal-function","display_name":"renal function","score":0.7020000219345093},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9810000061988831},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.6909999847412109},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.9259999990463257},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":0.8190000057220459},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.7570000290870667},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.9929999709129333},{"id":"https://openalex.org/keywords/superoxide-dismutase","display_name":"superoxide dismutase","score":0.9739999771118164},{"id":"https://openalex.org/keywords/catalase","display_name":"catalase","score":0.9929999709129333},{"id":"https://openalex.org/keywords/glutathione-peroxidase","display_name":"glutathione peroxidase","score":1.0},{"id":"https://openalex.org/keywords/fruit-extract","display_name":"fruit extract","score":0.6169999837875366},{"id":"https://openalex.org/keywords/creatinine-clearance","display_name":"creatinine clearance","score":0.7059999704360962}],"concepts":[{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.8419464826583862},{"id":"https://openalex.org/C126189478","wikidata":"https://www.wikidata.org/wiki/Q1468324","display_name":"Nephrotoxicity","level":3,"score":0.8297092914581299},{"id":"https://openalex.org/C544657597","wikidata":"https://www.wikidata.org/wiki/Q1091","display_name":"Cadmium","level":2,"score":0.5856376886367798},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.5837556719779968},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5228560566902161},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.5023553371429443},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4788260757923126},{"id":"https://openalex.org/C2777106384","wikidata":"https://www.wikidata.org/wiki/Q3153690","display_name":"Cadmium poisoning","level":3,"score":0.4489709734916687},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4217962622642517},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.2961769104003906},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15723839402198792},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/ph17101393","doi":"https://doi.org/10.3390/ph17101393","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ph17101393","pdf_url":"https://www.mdpi.com/1424-8247/17/10/1393/pdf?version=1729248067","source":{"id":"https://openalex.org/S16322639","display_name":"Pharmaceuticals","issn_l":"1424-8247","issn":["1424-8247"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceuticals","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11510283","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11510283","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11510283/pdf/pharmaceuticals-17-01393.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceuticals (Basel)","raw_type":"Text"},{"id":"pmid:39459032","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39459032","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceuticals (Basel, Switzerland)","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:bbc7159377f54569821ca521d1640be2","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/bbc7159377f54569821ca521d1640be2","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Pharmaceuticals, Vol 17, Iss 10, p 1393 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/ph17101393","doi":"https://doi.org/10.3390/ph17101393","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ph17101393","pdf_url":"https://www.mdpi.com/1424-8247/17/10/1393/pdf?version=1729248067","source":{"id":"https://openalex.org/S16322639","display_name":"Pharmaceuticals","issn_l":"1424-8247","issn":["1424-8247"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceuticals","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320325185","display_name":"Universidade Federal do Rio Grande do Norte","ror":"https://ror.org/04wn09761"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4403545208.pdf","grobid_xml":"https://content.openalex.org/works/W4403545208.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W1491753771","https://openalex.org/W1992668790","https://openalex.org/W1994763875","https://openalex.org/W1995528271","https://openalex.org/W1995997090","https://openalex.org/W2019600164","https://openalex.org/W2052552423","https://openalex.org/W2114889530","https://openalex.org/W2157950658","https://openalex.org/W2171981975","https://openalex.org/W2247174742","https://openalex.org/W2521574223","https://openalex.org/W2666833690","https://openalex.org/W2738913092","https://openalex.org/W2741427151","https://openalex.org/W2793554503","https://openalex.org/W2802880983","https://openalex.org/W2889576188","https://openalex.org/W2889784314","https://openalex.org/W2890279196","https://openalex.org/W2914332916","https://openalex.org/W2922040560","https://openalex.org/W2952286590","https://openalex.org/W2953960697","https://openalex.org/W2968838706","https://openalex.org/W2998980463","https://openalex.org/W3032103849","https://openalex.org/W3081787588","https://openalex.org/W3088196854","https://openalex.org/W3127654565","https://openalex.org/W3128230808","https://openalex.org/W3196028697","https://openalex.org/W3199837376","https://openalex.org/W3208973190","https://openalex.org/W3215552112","https://openalex.org/W4212865324","https://openalex.org/W4289176927","https://openalex.org/W4361299638","https://openalex.org/W4385732888"],"related_works":["https://openalex.org/W2262876765","https://openalex.org/W7096607414","https://openalex.org/W3091393565","https://openalex.org/W2017618453","https://openalex.org/W2019600164","https://openalex.org/W3190184963","https://openalex.org/W2791394018","https://openalex.org/W3027115439","https://openalex.org/W4413909397","https://openalex.org/W7126112204"],"abstract_inverted_index":{"Background:":[0],"Cadmium":[1],"(Cd),":[2],"a":[3,57,195],"highly":[4],"toxic":[5],"heavy":[6],"metal":[7],"from":[8,67],"agricultural":[9],"activities,":[10],"and":[11,34,53,76,90,125,131,137,152,164,170,176,201,208],"its":[12,31,206],"exposure":[13],"can":[14],"lead":[15],"to":[16,40,111,140,179],"impaired":[17],"renal":[18,48,113,212],"function":[19],"by":[20],"increasing":[21],"reactive":[22],"oxygen":[23],"species.":[24],"The":[25,116,147],"atemoya":[26,45,72,193],"fruit":[27],"is":[28],"known":[29],"for":[30,96,198],"high":[32],"phenolic":[33],"antioxidant":[35,207],"compounds.":[36],"This":[37,187],"study":[38,188],"aimed":[39],"evaluate":[41],"the":[42,71,141,180,190,203],"effects":[43],"of":[44,70,105,135,174,192,205],"extracts":[46,64,92,154],"on":[47],"function,":[49],"oxidative":[50],"stress":[51],"parameters,":[52],"inflammatory":[54],"biomarkers":[55],"in":[56,211],"cadmium-induced":[58],"nephrotoxicity":[59,200],"model.":[60],"Methods:":[61],"Three":[62],"aqueous":[63],"were":[65,82],"prepared":[66],"different":[68],"parts":[69],"fruit:":[73],"seeds,":[74],"peel,":[75,89,151],"pulp.":[77],"Twenty-five":[78],"male":[79],"Wistar":[80],"rats":[81],"allocated":[83],"into":[84],"four":[85],"groups:":[86],"control,":[87],"seed,":[88,150],"pulp":[91,153],"at":[93],"2":[94],"g/kg":[95],"25":[97],"days.":[98],"All":[99],"treatment":[100,148],"groups":[101,118],"administered":[102],"intraperitoneal":[103],"injections":[104],"cadmium":[106],"chloride":[107],"(CdCl2)":[108],"(2":[109],"mg/kg)":[110],"induce":[112],"damage.":[114],"Results:":[115],"cadmium-treated":[117],"showed":[119],"decreased":[120],"creatinine":[121,156],"clearance,":[122],"SOD,":[123,162],"CAT,":[124,163],"GPx":[126,165],"activities":[127,166],"(p":[128,144,158,167,183],"<":[129,145,159,168,184],"0.05)":[130],"increased":[132,155,161],"serum":[133,172],"levels":[134,173],"TNF-\u03b1":[136,175],"IL-6":[138,177],"compared":[139,178],"control":[142],"group":[143,182],"0.05).":[146,185],"with":[149],"clearance":[157],"0.05),":[160,169],"reduced":[171],"Cd":[181],"Conclusions:":[186],"supports":[189],"use":[191],"as":[194],"promising":[196],"candidate":[197],"mitigating":[199],"highlights":[202],"importance":[204],"anti-inflammatory":[209],"properties":[210],"health.":[213]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3}],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2024-10-19T00:00:00"}