{"id":"https://openalex.org/W4403519930","doi":"https://doi.org/10.1038/s42003-024-07056-x","title":"Insights into the molecular characteristics of embryonic cranial neural crest cells and their derived mesenchymal cell pools","display_name":"Insights into the molecular characteristics of embryonic cranial neural crest cells and their derived mesenchymal cell pools","publication_year":2024,"publication_date":"2024-10-18","ids":{"openalex":"https://openalex.org/W4403519930","doi":"https://doi.org/10.1038/s42003-024-07056-x","pmid":"https://pubmed.ncbi.nlm.nih.gov/39424998","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11489408"},"language":"en","primary_location":{"id":"doi:10.1038/s42003-024-07056-x","doi":"https://doi.org/10.1038/s42003-024-07056-x","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s42003-024-07056-x","pdf_url":"https://www.nature.com/articles/s42003-024-07056-x.pdf","source":{"id":"https://openalex.org/S4210225776","display_name":"Communications Biology","issn_l":"2399-3642","issn":["2399-3642"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-2","medline","norway-1","oarl","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Communications Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s42003-024-07056-x.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034056914","display_name":"Hengxing Ba","orcid":"https://orcid.org/0000-0003-0882-8841","observed_orcids":["https://orcid.org/0000-0003-0882-8841"]},"institutions":[{"id":"https://openalex.org/I4405281947","display_name":"Changchun Sci-Tech University","ror":"https://ror.org/0546zr232","country_code":"CN","type":"education","lineage":["https://openalex.org/I4405281947"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hengxing Ba","raw_affiliation_strings":["Jilin Provincial Key Laboratory of Deer Antler Biology, Institute of Antler Science and Product Technology, Changchun Sci-Tech University, 130600, Changchun, China. bahengxing@cstu.edu.cn","Jilin Provincial Key Laboratory of Deer Antler Biology, Institute of Antler Science and Product Technology, Changchun Sci-Tech University, 130600, Changchun, China"],"raw_orcid":"https://orcid.org/0000-0003-0882-8841","affiliations":[{"raw_affiliation_string":"Jilin Provincial Key Laboratory of Deer Antler Biology, Institute of Antler Science and Product Technology, Changchun Sci-Tech University, 130600, Changchun, China. bahengxing@cstu.edu.cn","institution_ids":["https://openalex.org/I4405281947"]},{"raw_affiliation_string":"Jilin Provincial Key Laboratory of Deer Antler Biology, Institute of Antler Science and Product Technology, Changchun Sci-Tech University, 130600, Changchun, China","institution_ids":["https://openalex.org/I4405281947"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060028507","display_name":"Qianqian Guo","orcid":"https://orcid.org/0000-0001-7983-3731","observed_orcids":["https://orcid.org/0000-0001-7983-3731"]},"institutions":[{"id":"https://openalex.org/I4405281947","display_name":"Changchun Sci-Tech University","ror":"https://ror.org/0546zr232","country_code":"CN","type":"education","lineage":["https://openalex.org/I4405281947"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qianqian Guo","raw_affiliation_strings":["Jilin Provincial Key Laboratory of Deer Antler Biology, Institute of Antler Science and Product Technology, Changchun Sci-Tech University, 130600, Changchun, China"],"raw_orcid":"https://orcid.org/0000-0001-7983-3731","affiliations":[{"raw_affiliation_string":"Jilin Provincial Key Laboratory of Deer Antler Biology, Institute of Antler Science and Product Technology, Changchun Sci-Tech University, 130600, Changchun, China","institution_ids":["https://openalex.org/I4405281947"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100841437","display_name":"Yudong Shang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405281947","display_name":"Changchun Sci-Tech University","ror":"https://ror.org/0546zr232","country_code":"CN","type":"education","lineage":["https://openalex.org/I4405281947"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yudong Shang","raw_affiliation_strings":["Jilin Provincial Key Laboratory of Deer Antler Biology, Institute of Antler Science and Product Technology, Changchun Sci-Tech University, 130600, Changchun, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jilin Provincial Key Laboratory of Deer Antler Biology, Institute of Antler Science and Product Technology, Changchun Sci-Tech University, 130600, Changchun, China","institution_ids":["https://openalex.org/I4405281947"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074404747","display_name":"Pengfei Hu","orcid":"https://orcid.org/0000-0003-3816-1849","observed_orcids":["https://orcid.org/0000-0003-3816-1849"]},"institutions":[{"id":"https://openalex.org/I4405281947","display_name":"Changchun Sci-Tech University","ror":"https://ror.org/0546zr232","country_code":"CN","type":"education","lineage":["https://openalex.org/I4405281947"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pengfei Hu","raw_affiliation_strings":["Jilin Provincial Key Laboratory of Deer Antler Biology, Institute of Antler Science and Product Technology, Changchun Sci-Tech University, 130600, Changchun, China"],"raw_orcid":"https://orcid.org/0000-0003-3816-1849","affiliations":[{"raw_affiliation_string":"Jilin Provincial Key Laboratory of Deer Antler Biology, Institute of Antler Science and Product Technology, Changchun Sci-Tech University, 130600, Changchun, China","institution_ids":["https://openalex.org/I4405281947"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Chao Ma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405281947","display_name":"Changchun Sci-Tech University","ror":"https://ror.org/0546zr232","country_code":"CN","type":"education","lineage":["https://openalex.org/I4405281947"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chao Ma","raw_affiliation_strings":["Jilin Provincial Key Laboratory of Deer Antler Biology, Institute of Antler Science and Product Technology, Changchun Sci-Tech University, 130600, Changchun, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jilin Provincial Key Laboratory of Deer Antler Biology, Institute of Antler Science and Product Technology, Changchun Sci-Tech University, 130600, Changchun, China","institution_ids":["https://openalex.org/I4405281947"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101612777","display_name":"Jiping Li","orcid":"https://orcid.org/0009-0002-8323-1770","observed_orcids":["https://orcid.org/0009-0002-8323-1770"]},"institutions":[{"id":"https://openalex.org/I4405281947","display_name":"Changchun Sci-Tech University","ror":"https://ror.org/0546zr232","country_code":"CN","type":"education","lineage":["https://openalex.org/I4405281947"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiping Li","raw_affiliation_strings":["Jilin Provincial Key Laboratory of Deer Antler Biology, Institute of Antler Science and Product Technology, Changchun Sci-Tech University, 130600, Changchun, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jilin Provincial Key Laboratory of Deer Antler Biology, Institute of Antler Science and Product Technology, Changchun Sci-Tech University, 130600, Changchun, China","institution_ids":["https://openalex.org/I4405281947"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045966670","display_name":"Dawn Elizabeth Coates","orcid":"https://orcid.org/0000-0003-4242-6846","observed_orcids":["https://orcid.org/0000-0003-4242-6846"]},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":true,"raw_author_name":"Dawn Elizabeth Coates","raw_affiliation_strings":["Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin, New Zealand. dawn.coates@otago.ac.nz","Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin, New Zealand"],"raw_orcid":"https://orcid.org/0000-0003-4242-6846","affiliations":[{"raw_affiliation_string":"Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin, New Zealand. dawn.coates@otago.ac.nz","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin, New Zealand","institution_ids":["https://openalex.org/I80281795"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100728490","display_name":"Chunyi Li","orcid":"https://orcid.org/0000-0001-7275-4440","observed_orcids":["https://orcid.org/0000-0001-7275-4440"]},"institutions":[{"id":"https://openalex.org/I4210152006","display_name":"Jilin Agricultural University","ror":"https://ror.org/05dmhhd41","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210152006"]},{"id":"https://openalex.org/I4405281947","display_name":"Changchun Sci-Tech University","ror":"https://ror.org/0546zr232","country_code":"CN","type":"education","lineage":["https://openalex.org/I4405281947"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Chunyi Li","raw_affiliation_strings":["College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, 130118, China. lichunyi1959@163.com","Jilin Provincial Key Laboratory of Deer Antler Biology, Institute of Antler Science and Product Technology, Changchun Sci-Tech University, 130600, Changchun, China. lichunyi1959@163.com","College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, 130118, China"],"raw_orcid":"https://orcid.org/0000-0001-7275-4440","affiliations":[{"raw_affiliation_string":"College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, 130118, China. lichunyi1959@163.com","institution_ids":["https://openalex.org/I4210152006"]},{"raw_affiliation_string":"Jilin Provincial Key Laboratory of Deer Antler Biology, Institute of Antler Science and Product Technology, Changchun Sci-Tech University, 130600, Changchun, China. lichunyi1959@163.com","institution_ids":["https://openalex.org/I4405281947"]},{"raw_affiliation_string":"College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, 130118, China","institution_ids":["https://openalex.org/I4210152006"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5034056914","https://openalex.org/A5045966670","https://openalex.org/A5100728490"],"corresponding_institution_ids":["https://openalex.org/I4210152006","https://openalex.org/I4405281947","https://openalex.org/I80281795"],"apc_list":{"value":3890,"currency":"USD","value_usd":3890},"apc_paid":{"value":3890,"currency":"USD","value_usd":3890},"fwci":1.2233,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.76364124,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"7","issue":"1","first_page":"1347","last_page":"1347"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.9320999979972839,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.9320999979972839,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.03020000085234642,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11919","display_name":"dental development and anomalies","score":0.007199999876320362,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cranial-neural-crest-cells","display_name":"cranial neural crest cells","score":0.9959999918937683},{"id":"https://openalex.org/keywords/mesenchymal-cells","display_name":"mesenchymal cells","score":0.7860000133514404},{"id":"https://openalex.org/keywords/antler-regeneration","display_name":"antler regeneration","score":0.75},{"id":"https://openalex.org/keywords/deer","display_name":"deer","score":0.6940000057220459},{"id":"https://openalex.org/keywords/periosteum","display_name":"periosteum","score":0.7509999871253967},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.9509999752044678},{"id":"https://openalex.org/keywords/hypomethylation","display_name":"hypomethylation","score":0.8600000143051147},{"id":"https://openalex.org/keywords/multipotency","display_name":"multipotency","score":0.921999990940094},{"id":"https://openalex.org/keywords/signature-genes","display_name":"signature genes","score":0.5680000185966492},{"id":"https://openalex.org/keywords/single-cell-transcriptomics","display_name":"single-cell transcriptomics","score":0.6489999890327454},{"id":"https://openalex.org/keywords/tissue-regeneration","display_name":"tissue regeneration","score":0.6629999876022339}],"concepts":[{"id":"https://openalex.org/C126749454","wikidata":"https://www.wikidata.org/wiki/Q1348455","display_name":"Neural crest","level":3,"score":0.8417980670928955},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.8252295255661011},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.695697546005249},{"id":"https://openalex.org/C2780071072","wikidata":"https://www.wikidata.org/wiki/Q5182130","display_name":"Cranial neural crest","level":4,"score":0.685490071773529},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5396443009376526},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5232309699058533},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.4474041759967804},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.3908354341983795},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.36727917194366455},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.32886970043182373},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.22684702277183533},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.22356438636779785},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.12840747833251953}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000999","descriptor_name":"Antlers","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003670","descriptor_name":"Deer","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D003670","descriptor_name":"Deer","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009432","descriptor_name":"Neural Crest","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D009432","descriptor_name":"Neural Crest","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D009432","descriptor_name":"Neural Crest","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012886","descriptor_name":"Skull","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D012886","descriptor_name":"Skull","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D012886","descriptor_name":"Skull","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014070","descriptor_name":"Tooth","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D014070","descriptor_name":"Tooth","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059630","descriptor_name":"Mesenchymal Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D059630","descriptor_name":"Mesenchymal Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1038/s42003-024-07056-x","doi":"https://doi.org/10.1038/s42003-024-07056-x","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s42003-024-07056-x","pdf_url":"https://www.nature.com/articles/s42003-024-07056-x.pdf","source":{"id":"https://openalex.org/S4210225776","display_name":"Communications Biology","issn_l":"2399-3642","issn":["2399-3642"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-2","medline","norway-1","oarl","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Communications Biology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11489408","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11489408","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11489408/pdf/42003_2024_Article_7056.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Commun Biol","raw_type":"Text"},{"id":"pmid:39424998","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39424998","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Communications biology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:6cd71563bfda417c8299cb9e78f70d35","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/6cd71563bfda417c8299cb9e78f70d35","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s42003-024-07056-x","doi":"https://doi.org/10.1038/s42003-024-07056-x","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s42003-024-07056-x","pdf_url":"https://www.nature.com/articles/s42003-024-07056-x.pdf","source":{"id":"https://openalex.org/S4210225776","display_name":"Communications Biology","issn_l":"2399-3642","issn":["2399-3642"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-2","medline","norway-1","oarl","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Communications Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.5683000087738037,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6369939533","display_name":null,"funder_award_id":"32470892","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6554442618","display_name":null,"funder_award_id":"YDZJ202201ZYTS690","funder_id":"https://openalex.org/F4320310121","funder_display_name":"Natural Science Foundation of Jilin Province"},{"id":"https://openalex.org/G8583212055","display_name":null,"funder_award_id":"U20A20403","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320310121","display_name":"Natural Science Foundation of Jilin Province","ror":null},{"id":"https://openalex.org/F4320316081","display_name":"Jilin Province Development and Reform Commission","ror":"https://ror.org/0331mqm40"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322174","display_name":"People's Government of Jilin Province","ror":"https://ror.org/02fzqav45"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4403519930.pdf","grobid_xml":"https://content.openalex.org/works/W4403519930.grobid-xml"},"referenced_works_count":67,"referenced_works":["https://openalex.org/W1900937478","https://openalex.org/W1967064280","https://openalex.org/W1975470952","https://openalex.org/W1987557775","https://openalex.org/W1993419851","https://openalex.org/W1995033304","https://openalex.org/W2001237524","https://openalex.org/W2006963431","https://openalex.org/W2012330620","https://openalex.org/W2026343134","https://openalex.org/W2028288970","https://openalex.org/W2048196231","https://openalex.org/W2064122267","https://openalex.org/W2068469234","https://openalex.org/W2072720521","https://openalex.org/W2074842192","https://openalex.org/W2081208184","https://openalex.org/W2086210388","https://openalex.org/W2093403692","https://openalex.org/W2098219129","https://openalex.org/W2102930587","https://openalex.org/W2110092516","https://openalex.org/W2131374955","https://openalex.org/W2158019017","https://openalex.org/W2159675211","https://openalex.org/W2250973263","https://openalex.org/W2305364952","https://openalex.org/W2464410938","https://openalex.org/W2520340320","https://openalex.org/W2591765579","https://openalex.org/W2604980022","https://openalex.org/W2616922646","https://openalex.org/W2765869110","https://openalex.org/W2791851888","https://openalex.org/W2886448569","https://openalex.org/W2908570968","https://openalex.org/W2910238842","https://openalex.org/W2948517648","https://openalex.org/W2948686132","https://openalex.org/W2953151710","https://openalex.org/W2966139022","https://openalex.org/W2969537119","https://openalex.org/W2984472267","https://openalex.org/W2987429763","https://openalex.org/W2994211761","https://openalex.org/W2995410603","https://openalex.org/W2998632984","https://openalex.org/W3020186011","https://openalex.org/W3087790240","https://openalex.org/W3103797259","https://openalex.org/W3119092178","https://openalex.org/W3153012503","https://openalex.org/W3164692211","https://openalex.org/W3179788429","https://openalex.org/W3196743603","https://openalex.org/W3199464241","https://openalex.org/W4220831425","https://openalex.org/W4283008442","https://openalex.org/W4291916319","https://openalex.org/W4293576615","https://openalex.org/W4312095354","https://openalex.org/W4321748531","https://openalex.org/W4328048326","https://openalex.org/W4383757492","https://openalex.org/W4385813866","https://openalex.org/W4386980281","https://openalex.org/W4390744586"],"related_works":["https://openalex.org/W4390698100","https://openalex.org/W155246264","https://openalex.org/W4285412860","https://openalex.org/W2023849906","https://openalex.org/W4403739496","https://openalex.org/W2037223015","https://openalex.org/W2957646247","https://openalex.org/W2003360171","https://openalex.org/W7100173593","https://openalex.org/W4291916319"],"abstract_inverted_index":{"Neural":[0],"crest":[1,31],"cells":[2,89],"(NCCs)":[3],"are":[4],"central":[5],"to":[6,12],"vertebrate":[7],"embryonic":[8],"development,":[9],"giving":[10],"rise":[11],"diverse":[13],"cell":[14,32,102],"types":[15],"with":[16,111],"unique":[17],"migratory":[18],"and":[19,48,70,90,99,113,121,157],"differentiation":[20],"capacities.":[21],"This":[22],"study":[23],"examines":[24],"the":[25,154],"molecular":[26],"characteristics":[27],"of":[28,97,133,160],"cranial":[29],"neural":[30],"(CNCC)-derived":[33],"mesenchymal":[34,72,93,101,124,162],"cells,":[35,73,163],"specifically":[36],"those":[37],"from":[38],"teeth":[39],"which":[40,50],"in":[41,83,138,145,171],"deer":[42],"show":[43],"continuous":[44],"but":[45],"limited":[46],"growth,":[47],"antlers,":[49],"exhibit":[51],"remarkable":[52],"regenerative":[53,139,158],"capabilities.":[54],"Here,":[55],"through":[56],"single-cell":[57],"RNA":[58],"sequencing":[59],"analysis,":[60],"we":[61],"uncover":[62],"shared":[63],"gene":[64],"expression":[65],"profiles":[66],"between":[67,86,119],"adult":[68,123],"antlerogenic":[69,87,140],"dental":[71,91],"indicating":[74],"common":[75],"developmental":[76,155],"pathways.":[77],"We":[78],"identify":[79],"a":[80,143,165],"striking":[81],"resemblance":[82],"transcriptomic":[84],"features":[85],"progenitor":[88],"pulp":[92],"cells.":[94],"Comparative":[95],"analysis":[96,130],"CNCC-derived":[98,122,161],"non-CNCC-derived":[100],"pools":[103],"across":[104],"species":[105],"reveals":[106],"core":[107],"signature":[108,136],"genes":[109,137],"associated":[110],"CNCCs":[112,120],"their":[114],"derivatives,":[115],"delineating":[116],"essential":[117],"connections":[118],"pools.":[125],"Furthermore,":[126],"whole-genome":[127],"DNA":[128],"methylation":[129],"unveils":[131],"hypomethylation":[132],"CNCC":[134],"derivate":[135],"periosteum,":[141],"implying":[142],"role":[144],"maintaining":[146],"multipotency.":[147],"These":[148],"findings":[149],"offer":[150],"crucial":[151],"insights":[152],"into":[153],"biology":[156],"potential":[159],"laying":[164],"foundation":[166],"for":[167],"innovative":[168],"therapeutic":[169],"strategies":[170],"tissue":[172],"regeneration.":[173]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-10-18T00:00:00"}