{"id":"https://openalex.org/W4403440887","doi":"https://doi.org/10.3389/fendo.2024.1433553","title":"Current status of the prediction for radio-iodine refractory thyroid cancer: a narrative review","display_name":"Current status of the prediction for radio-iodine refractory thyroid cancer: a narrative review","publication_year":2024,"publication_date":"2024-10-15","ids":{"openalex":"https://openalex.org/W4403440887","doi":"https://doi.org/10.3389/fendo.2024.1433553","pmid":"https://pubmed.ncbi.nlm.nih.gov/39473509","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11518765"},"language":"en","primary_location":{"id":"doi:10.3389/fendo.2024.1433553","doi":"https://doi.org/10.3389/fendo.2024.1433553","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fendo.2024.1433553","pdf_url":null,"source":{"id":"https://openalex.org/S2597401208","display_name":"Frontiers in Endocrinology","issn_l":"1664-2392","issn":["1664-2392"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Endocrinology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W4403440887"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3389/fendo.2024.1433553","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100325317","display_name":"Yuhua Wang","orcid":"https://orcid.org/0009-0003-5099-8614","observed_orcids":["https://orcid.org/0009-0003-5099-8614"]},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]},{"id":"https://openalex.org/I4210125748","display_name":"First Hospital of Shanxi Medical University","ror":"https://ror.org/02vzqaq35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210125748"]},{"id":"https://openalex.org/I4210158804","display_name":"Shanxi Academy of Medical Sciences","ror":"https://ror.org/04tshhm50","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158804"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuhua Wang","raw_affiliation_strings":["Department of Nuclear Medicine, First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan, Shanxi, China","Department of Nuclear Medicine, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, Shanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nuclear Medicine, First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan, Shanxi, China","institution_ids":["https://openalex.org/I17721919","https://openalex.org/I4210125748"]},{"raw_affiliation_string":"Department of Nuclear Medicine, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, Shanxi, China","institution_ids":["https://openalex.org/I17721919","https://openalex.org/I4210158804"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059012322","display_name":"Xiurong Lu","orcid":"https://orcid.org/0000-0001-8531-1219","observed_orcids":["https://orcid.org/0000-0001-8531-1219"]},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]},{"id":"https://openalex.org/I4210125748","display_name":"First Hospital of Shanxi Medical University","ror":"https://ror.org/02vzqaq35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210125748"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiurong Lu","raw_affiliation_strings":["Department of Nuclear Medicine, First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan, Shanxi, China","Department of Nuclear Medicine, Linfen Central Hospital of Shanxi Province, Linfen, Shanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nuclear Medicine, First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan, Shanxi, China","institution_ids":["https://openalex.org/I17721919","https://openalex.org/I4210125748"]},{"raw_affiliation_string":"Department of Nuclear Medicine, Linfen Central Hospital of Shanxi Province, Linfen, Shanxi, China","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049584421","display_name":"Haiyan Liu","orcid":"https://orcid.org/0000-0002-4652-469X","observed_orcids":["https://orcid.org/0000-0002-4652-469X"]},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]},{"id":"https://openalex.org/I4210125748","display_name":"First Hospital of Shanxi Medical University","ror":"https://ror.org/02vzqaq35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210125748"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Haiyan Liu","raw_affiliation_strings":["Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan, Shanxi, China","Department of Nuclear Medicine, First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan, Shanxi, China","Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan, Shanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan, Shanxi, China","institution_ids":["https://openalex.org/I17721919"]},{"raw_affiliation_string":"Department of Nuclear Medicine, First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan, Shanxi, China","institution_ids":["https://openalex.org/I17721919","https://openalex.org/I4210125748"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan, Shanxi, China","institution_ids":["https://openalex.org/I17721919"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5049584421"],"corresponding_institution_ids":["https://openalex.org/I17721919","https://openalex.org/I4210125748"],"apc_list":{"value":3295,"currency":"USD","value_usd":3295},"apc_paid":{"value":3295,"currency":"USD","value_usd":3295},"fwci":0.2813,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.35268185,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"15","issue":null,"first_page":"1433553","last_page":"1433553"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10329","display_name":"Thyroid Cancer Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10329","display_name":"Thyroid Cancer Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11728","display_name":"Thyroid and Parathyroid Surgery","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/predictive-model","display_name":"prediction model","score":0.7319999933242798},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.6470000147819519},{"id":"https://openalex.org/keywords/differentiated-thyroid-cancer","display_name":"differentiated thyroid cancer","score":0.8920000195503235},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.7929999828338623},{"id":"https://openalex.org/keywords/serum-biomarkers","display_name":"serum biomarkers","score":0.6169999837875366},{"id":"https://openalex.org/keywords/pet-ct","display_name":"PET/CT","score":0.8960000276565552},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.36000001430511475}],"concepts":[{"id":"https://openalex.org/C2779761222","wikidata":"https://www.wikidata.org/wiki/Q826522","display_name":"Thyroid cancer","level":3,"score":0.5939028263092041},{"id":"https://openalex.org/C142424586","wikidata":"https://www.wikidata.org/wiki/Q7307572","display_name":"Refractory (planetary science)","level":2,"score":0.5237669348716736},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4960115849971771},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4830387532711029},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.47420409321784973},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4487067461013794},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.35728806257247925},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.1461813747882843},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.093841552734375}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007457","descriptor_name":"Iodine Radioisotopes","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.3389/fendo.2024.1433553","doi":"https://doi.org/10.3389/fendo.2024.1433553","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fendo.2024.1433553","pdf_url":null,"source":{"id":"https://openalex.org/S2597401208","display_name":"Frontiers in Endocrinology","issn_l":"1664-2392","issn":["1664-2392"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Endocrinology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11518765","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11518765","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11518765/pdf/fendo-15-1433553.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Endocrinol (Lausanne)","raw_type":"Text"},{"id":"pmid:39473509","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39473509","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in endocrinology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:6c23b61d01c9425493971f0f87c60f0c","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/6c23b61d01c9425493971f0f87c60f0c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Endocrinology, Vol 15 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fendo.2024.1433553","doi":"https://doi.org/10.3389/fendo.2024.1433553","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fendo.2024.1433553","pdf_url":null,"source":{"id":"https://openalex.org/S2597401208","display_name":"Frontiers in Endocrinology","issn_l":"1664-2392","issn":["1664-2392"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Endocrinology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2158803486","display_name":null,"funder_award_id":"82372009","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4403440887.pdf","grobid_xml":"https://content.openalex.org/works/W4403440887.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W2040642592","https://openalex.org/W2098239437","https://openalex.org/W2145150141","https://openalex.org/W2171379946","https://openalex.org/W2186464704","https://openalex.org/W2501291663","https://openalex.org/W2532678329","https://openalex.org/W2735430562","https://openalex.org/W2794378874","https://openalex.org/W2880775428","https://openalex.org/W2893360679","https://openalex.org/W2948063335","https://openalex.org/W2953653667","https://openalex.org/W2964334135","https://openalex.org/W2972693147","https://openalex.org/W2975327420","https://openalex.org/W2976988657","https://openalex.org/W2980584272","https://openalex.org/W2998437538","https://openalex.org/W3090212623","https://openalex.org/W3121034517","https://openalex.org/W3128646645","https://openalex.org/W3135564712","https://openalex.org/W3159027907","https://openalex.org/W3206673809","https://openalex.org/W3216868217","https://openalex.org/W4224255270","https://openalex.org/W4225282305","https://openalex.org/W4280538543","https://openalex.org/W4283662141","https://openalex.org/W4288749761","https://openalex.org/W4303628442","https://openalex.org/W4313455143","https://openalex.org/W4319985307","https://openalex.org/W4322505297","https://openalex.org/W4381801293","https://openalex.org/W4382502077","https://openalex.org/W4382881418","https://openalex.org/W4388234085","https://openalex.org/W4389619197","https://openalex.org/W4393993240","https://openalex.org/W4404012564"],"related_works":["https://openalex.org/W4393993240","https://openalex.org/W4319985307","https://openalex.org/W4389619197","https://openalex.org/W2893360679","https://openalex.org/W4399658020","https://openalex.org/W4322505297","https://openalex.org/W7144168165","https://openalex.org/W4412881388","https://openalex.org/W7158460368","https://openalex.org/W4415226927"],"abstract_inverted_index":{"It":[0],"is":[1,29,36],"well":[2],"established":[3],"that":[4,75,104],"patients":[5],"with":[6],"the":[7,18,32,40,73,79,106,121,126,138,145],"most":[8],"differentiated":[9],"thyroid":[10,24],"cancers":[11],"have":[12,48,56,97],"a":[13,52],"good":[14],"prognosis,":[15],"whereas":[16],"when":[17],"disease":[19,92],"develops":[20],"into":[21],"radio-iodine":[22],"refractory":[23],"cancer":[25],"(RAIR)":[26],"their":[27,149],"prognosis":[28],"poor":[30],"and":[31,47,77,94,137],"10-year":[33],"survival":[34],"rate":[35],"low.":[37],"At":[38],"present,":[39],"therapeutic":[41],"methods":[42],"for":[43,59,129],"RAIR":[44,131],"are":[45,142],"limited":[46],"low":[49],"efficacy.":[50],"As":[51],"consequence,":[53],"several":[54],"models":[55,117,128],"been":[57,98],"developed":[58],"predicting":[60,130],"RAIR.":[61,82,109,124],"The":[62,110],"aim":[63],"of":[64,81,108,123],"this":[65],"review":[66],"was":[67],"to":[68,100,147],"describe":[69],"recent":[70],"developments":[71],"regarding":[72],"factors":[74,103],"influence":[76,105],"predict":[78],"occurrence":[80],"Many":[83],"variables":[84],"including":[85],"demographic":[86],"characteristics,":[87,93],"tumor":[88],"clinicopathology,":[89],"serology":[90],"changes,":[91],"PET/CT":[95],"results":[96],"shown":[99],"be":[101],"independent":[102],"development":[107],"cut-off":[111],"value":[112],"derived":[113],"from":[114],"multivariate":[115],"prediction":[116,140],"therefore":[118],"effectively":[119],"predicts":[120],"onset":[122],"However,":[125],"current":[127],"were":[132],"obtained":[133],"through":[134],"retrospective":[135],"studies,":[136],"prospective":[139],"studies":[141],"needed":[143],"in":[144],"future":[146],"confirm":[148],"validity.":[150]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2024-10-16T00:00:00"}
