{"id":"https://openalex.org/W4403342578","doi":"https://doi.org/10.1016/b978-0-443-19041-4.00059-5","title":"The aging brain","display_name":"The aging brain","publication_year":2024,"publication_date":"2024-10-11","ids":{"openalex":"https://openalex.org/W4403342578","doi":"https://doi.org/10.1016/b978-0-443-19041-4.00059-5"},"language":"en","primary_location":{"id":"doi:10.1016/b978-0-443-19041-4.00059-5","doi":"https://doi.org/10.1016/b978-0-443-19041-4.00059-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-443-19041-4.00059-5","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4403341957","display_name":"Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease"},"type":"book-chapter","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053925326","display_name":"Ian H. Guldner","orcid":"https://orcid.org/0000-0001-8715-136X","observed_orcids":["https://orcid.org/0000-0001-8715-136X"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ian H. Guldner","raw_affiliation_strings":["Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, United States","Wu Tsai Neurosciences Institute, Stanford University School of Medicine, Stanford, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, United States","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"raw_affiliation_string":"Wu Tsai Neurosciences Institute, Stanford University School of Medicine, Stanford, CA, United States","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027893468","display_name":"Tony Wyss\u2010Coray","orcid":"https://orcid.org/0000-0001-5893-0831","observed_orcids":["https://orcid.org/0000-0001-5893-0831"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tony Wyss-Coray","raw_affiliation_strings":["Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, United States","Paul F. Glenn Center for the Biology of Aging, Stanford University, Stanford, CA, United States","Stanford University, The Knight Initiative for Brain Resilience, Stanford, CA, United States","The Phil and Penny Knight Initiative for Brain Resilience, Stanford University, Stanford, CA, United States","Wu Tsai Neurosciences Institute, Stanford University School of Medicine, Stanford, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, United States","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"raw_affiliation_string":"Paul F. Glenn Center for the Biology of Aging, Stanford University, Stanford, CA, United States","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University, The Knight Initiative for Brain Resilience, Stanford, CA, United States","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"The Phil and Penny Knight Initiative for Brain Resilience, Stanford University, Stanford, CA, United States","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Wu Tsai Neurosciences Institute, Stanford University School of Medicine, Stanford, CA, United States","institution_ids":["https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.37878788,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"287","last_page":"300"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10676","display_name":"Genetics, Aging, and Longevity in Model Organisms","score":0.8931000232696533,"subfield":{"id":"https://openalex.org/subfields/1302","display_name":"Aging"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10676","display_name":"Genetics, Aging, and Longevity in Model Organisms","score":0.8931000232696533,"subfield":{"id":"https://openalex.org/subfields/1302","display_name":"Aging"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11265","display_name":"Aging and Gerontology Research","score":0.01720000058412552,"subfield":{"id":"https://openalex.org/subfields/3204","display_name":"Developmental and Educational Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.01510000042617321,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brain-aging","display_name":"brain aging","score":0.9089999794960022},{"id":"https://openalex.org/keywords/healthy-brain-aging","display_name":"healthy brain aging","score":0.9549999833106995},{"id":"https://openalex.org/keywords/hallmarks-of-aging","display_name":"hallmarks of aging","score":0.8029999732971191},{"id":"https://openalex.org/keywords/neurodegenerative-diseases","display_name":"neurodegenerative diseases","score":0.8740000128746033},{"id":"https://openalex.org/keywords/cognitive-decline","display_name":"cognitive decline","score":0.9589999914169312},{"id":"https://openalex.org/keywords/memory-retrieval","display_name":"memory retrieval","score":0.414000004529953},{"id":"https://openalex.org/keywords/processing-speed","display_name":"processing speed","score":0.6069999933242798},{"id":"https://openalex.org/keywords/cellular-senescence","display_name":"cellular senescence","score":0.6140000224113464},{"id":"https://openalex.org/keywords/organelle-dysfunction","display_name":"organelle dysfunction","score":0.6389999985694885},{"id":"https://openalex.org/keywords/molecular-aging","display_name":"molecular aging","score":0.7820000052452087},{"id":"https://openalex.org/keywords/exercise","display_name":"physical activity","score":0.4129999876022339},{"id":"https://openalex.org/keywords/caloric-restriction","display_name":"caloric restriction","score":0.9990000128746033},{"id":"https://openalex.org/keywords/anti-aging-interventions","display_name":"anti-aging interventions","score":0.7609999775886536},{"id":"https://openalex.org/keywords/mouse-model","display_name":"mouse model","score":0.9649999737739563}],"concepts":[{"id":"https://openalex.org/C2993665655","wikidata":"https://www.wikidata.org/wiki/Q4692577","display_name":"Brain aging","level":3,"score":0.5455964207649231},{"id":"https://openalex.org/C2779695026","wikidata":"https://www.wikidata.org/wiki/Q4692577","display_name":"Aging brain","level":3,"score":0.4535742998123169},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.41791510581970215},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3699048161506653},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.07037761807441711}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/b978-0-443-19041-4.00059-5","doi":"https://doi.org/10.1016/b978-0-443-19041-4.00059-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-443-19041-4.00059-5","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":107,"referenced_works":["https://openalex.org/W8577148","https://openalex.org/W1518586105","https://openalex.org/W1738529902","https://openalex.org/W1742446313","https://openalex.org/W1959902108","https://openalex.org/W1964223452","https://openalex.org/W1964413344","https://openalex.org/W1966132436","https://openalex.org/W1972965665","https://openalex.org/W1977370225","https://openalex.org/W1978927200","https://openalex.org/W1990958459","https://openalex.org/W1994947322","https://openalex.org/W1997485587","https://openalex.org/W2001980841","https://openalex.org/W2014760764","https://openalex.org/W2022272216","https://openalex.org/W2023831571","https://openalex.org/W2024215142","https://openalex.org/W2028791716","https://openalex.org/W2030803494","https://openalex.org/W2060535344","https://openalex.org/W2061169091","https://openalex.org/W2062729049","https://openalex.org/W2067028731","https://openalex.org/W2067084090","https://openalex.org/W2088939177","https://openalex.org/W2091793050","https://openalex.org/W2101967150","https://openalex.org/W2126525177","https://openalex.org/W2128084403","https://openalex.org/W2135771073","https://openalex.org/W2149591661","https://openalex.org/W2153367517","https://openalex.org/W2165981731","https://openalex.org/W2194304382","https://openalex.org/W2234976655","https://openalex.org/W2555579193","https://openalex.org/W2558150501","https://openalex.org/W2572710398","https://openalex.org/W2734706909","https://openalex.org/W2773711501","https://openalex.org/W2774506962","https://openalex.org/W2790139801","https://openalex.org/W2791286257","https://openalex.org/W2792158423","https://openalex.org/W2799445278","https://openalex.org/W2806146174","https://openalex.org/W2890865075","https://openalex.org/W2901550516","https://openalex.org/W2903107073","https://openalex.org/W2913940235","https://openalex.org/W2914968800","https://openalex.org/W2937046550","https://openalex.org/W2954434934","https://openalex.org/W2968658941","https://openalex.org/W2972368830","https://openalex.org/W2973204012","https://openalex.org/W2978969137","https://openalex.org/W2990428470","https://openalex.org/W2991456852","https://openalex.org/W2993902743","https://openalex.org/W3000061011","https://openalex.org/W3000319248","https://openalex.org/W3015526708","https://openalex.org/W3024769857","https://openalex.org/W3025772309","https://openalex.org/W3027937349","https://openalex.org/W3028951531","https://openalex.org/W3037075288","https://openalex.org/W3038299436","https://openalex.org/W3041860193","https://openalex.org/W3045630140","https://openalex.org/W3046027807","https://openalex.org/W3103505494","https://openalex.org/W3108796188","https://openalex.org/W3111207111","https://openalex.org/W3120956708","https://openalex.org/W3129648906","https://openalex.org/W3132792208","https://openalex.org/W3158627234","https://openalex.org/W3174540654","https://openalex.org/W3184188306","https://openalex.org/W3190631166","https://openalex.org/W3198616044","https://openalex.org/W3199223754","https://openalex.org/W3201931145","https://openalex.org/W3204566092","https://openalex.org/W3205323262","https://openalex.org/W4205928060","https://openalex.org/W4214946132","https://openalex.org/W4220864844","https://openalex.org/W4220972523","https://openalex.org/W4225246927","https://openalex.org/W4280630796","https://openalex.org/W4283167167","https://openalex.org/W4292488030","https://openalex.org/W4293574984","https://openalex.org/W4307233008","https://openalex.org/W4308037687","https://openalex.org/W4308298493","https://openalex.org/W4313312704","https://openalex.org/W4313422811","https://openalex.org/W4316506839","https://openalex.org/W4367176322","https://openalex.org/W4385880069","https://openalex.org/W4399075726"],"related_works":["https://openalex.org/W2195449432","https://openalex.org/W4407321167","https://openalex.org/W7167604816","https://openalex.org/W2966834762","https://openalex.org/W4415751668","https://openalex.org/W4386190816","https://openalex.org/W4255357697","https://openalex.org/W6931691719","https://openalex.org/W4310275847","https://openalex.org/W2765456985"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2024-10-12T00:00:00"}