{"id":"https://openalex.org/W4403225366","doi":"https://doi.org/10.47391/jpma-bagh-16-39","title":"The relationship between vitamin D status and disease activity in Iraqi systemic lupus erythematosus patients","display_name":"The relationship between vitamin D status and disease activity in Iraqi systemic lupus erythematosus patients","publication_year":2024,"publication_date":"2024-09-28","ids":{"openalex":"https://openalex.org/W4403225366","doi":"https://doi.org/10.47391/jpma-bagh-16-39","pmid":"https://pubmed.ncbi.nlm.nih.gov/39434298"},"language":"en","primary_location":{"id":"doi:10.47391/jpma-bagh-16-39","doi":"https://doi.org/10.47391/jpma-bagh-16-39","is_oa":true,"landing_page_url":"https://doi.org/10.47391/jpma-bagh-16-39","pdf_url":null,"source":{"id":"https://openalex.org/S26751084","display_name":"Journal of the Pakistan Medical Association","issn_l":"0030-9982","issn":["0030-9982"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","dongbi-d","medline","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4320800574","host_organization_name":"Pakistan Medical Association","host_organization_lineage":["https://openalex.org/P4320800574"],"host_organization_lineage_names":["Pakistan Medical Association"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Pakistan Medical Association","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.47391/jpma-bagh-16-39","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113423437","display_name":"Zamin A. Al-Sarray","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210103044","display_name":"Ministry of Health","ror":"https://ror.org/01b1c8m98","country_code":"IQ","type":"government","lineage":["https://openalex.org/I4210103044"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"Zamin Abdulhusssein Al-Sarray","raw_affiliation_strings":["Imamein Kadhimen Medical City, Ministry of Health and Environment Iraq"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Imamein Kadhimen Medical City, Ministry of Health and Environment Iraq","institution_ids":["https://openalex.org/I4210103044"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111147442","display_name":"Raghad Hassan Hussein","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115078","display_name":"Middle Technical University","ror":"https://ror.org/02fvkg758","country_code":"IQ","type":"education","lineage":["https://openalex.org/I4210115078"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"Raghad Hassan Hussein","raw_affiliation_strings":["Middle Technical University, College of Health and Medical Technology, Baghdad Iraq"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Middle Technical University, College of Health and Medical Technology, Baghdad Iraq","institution_ids":["https://openalex.org/I4210115078"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071000026","display_name":"Ali Hussein Al-Hafidh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115078","display_name":"Middle Technical University","ror":"https://ror.org/02fvkg758","country_code":"IQ","type":"education","lineage":["https://openalex.org/I4210115078"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"Ali Hussein Al-Hafidh","raw_affiliation_strings":["Middle Technical University, College of Health and Medical Technology, Baghdad Iraq"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Middle Technical University, College of Health and Medical Technology, Baghdad Iraq","institution_ids":["https://openalex.org/I4210115078"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089702692","display_name":"Izzat Al-Rayahi","orcid":"https://orcid.org/0000-0002-2538-7104","observed_orcids":["https://orcid.org/0000-0002-2538-7104"]},"institutions":[{"id":"https://openalex.org/I4210115078","display_name":"Middle Technical University","ror":"https://ror.org/02fvkg758","country_code":"IQ","type":"education","lineage":["https://openalex.org/I4210115078"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"Izzat Abdulsatar Al-Rayahi","raw_affiliation_strings":["Middle Technical University, College of Health and Medical Technology, Baghdad Iraq"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Middle Technical University, College of Health and Medical Technology, Baghdad Iraq","institution_ids":["https://openalex.org/I4210115078"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":650,"currency":"USD","value_usd":650},"apc_paid":{"value":650,"currency":"USD","value_usd":650},"fwci":0.2466,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.46992126,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"74","issue":"10 (Supple-08)","first_page":"S176","last_page":"S180"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.00930000003427267,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11330","display_name":"Systemic Sclerosis and Related Diseases","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/systemic-lupus-erythematosus","display_name":"systemic lupus erythematosus","score":0.9890000224113464},{"id":"https://openalex.org/keywords/vitamin-d-deficiency","display_name":"vitamin D deficiency","score":0.9929999709129333},{"id":"https://openalex.org/keywords/vitamin-d-insufficiency","display_name":"vitamin D insufficiency","score":0.984000027179718},{"id":"https://openalex.org/keywords/disease-activity","display_name":"disease activity","score":0.9539999961853027},{"id":"https://openalex.org/keywords/25-hydroxyvitamin-d","display_name":"25-hydroxyvitamin D","score":0.921999990940094},{"id":"https://openalex.org/keywords/complement-c3","display_name":"complement C3","score":0.8429999947547913},{"id":"https://openalex.org/keywords/complement-c4","display_name":"complement C4","score":1.0},{"id":"https://openalex.org/keywords/anti-dsdna-antibodies","display_name":"anti-dsDNA antibodies","score":0.9240000247955322},{"id":"https://openalex.org/keywords/iraqi-patients","display_name":"Iraqi patients","score":0.8140000104904175}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7332078814506531},{"id":"https://openalex.org/C124490489","wikidata":"https://www.wikidata.org/wiki/Q7936963","display_name":"Vitamin D and neurology","level":2,"score":0.646608829498291},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5388720631599426},{"id":"https://openalex.org/C2776912625","wikidata":"https://www.wikidata.org/wiki/Q1485","display_name":"Systemic lupus erythematosus","level":3,"score":0.49302932620048523},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4581555128097534},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.3864952325820923},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.23582327365875244}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003176","descriptor_name":"Complement C3","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D003176","descriptor_name":"Complement C3","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003181","descriptor_name":"Complement C4","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D003181","descriptor_name":"Complement C4","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007493","descriptor_name":"Iraq","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014807","descriptor_name":"Vitamin D","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D014807","descriptor_name":"Vitamin D","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D014808","descriptor_name":"Vitamin D Deficiency","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D014808","descriptor_name":"Vitamin D Deficiency","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D014808","descriptor_name":"Vitamin D Deficiency","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.47391/jpma-bagh-16-39","doi":"https://doi.org/10.47391/jpma-bagh-16-39","is_oa":true,"landing_page_url":"https://doi.org/10.47391/jpma-bagh-16-39","pdf_url":null,"source":{"id":"https://openalex.org/S26751084","display_name":"Journal of the Pakistan Medical Association","issn_l":"0030-9982","issn":["0030-9982"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","dongbi-d","medline","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4320800574","host_organization_name":"Pakistan Medical Association","host_organization_lineage":["https://openalex.org/P4320800574"],"host_organization_lineage_names":["Pakistan Medical Association"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Pakistan Medical Association","raw_type":"journal-article"},{"id":"pmid:39434298","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39434298","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JPMA. The Journal of the Pakistan Medical Association","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:e5e9cc4909614417b8255a6a2eb5e4a8","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/e5e9cc4909614417b8255a6a2eb5e4a8","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of the Pakistan Medical Association, Vol 74, Iss 10 (Supple-08) (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.47391/jpma-bagh-16-39","doi":"https://doi.org/10.47391/jpma-bagh-16-39","is_oa":true,"landing_page_url":"https://doi.org/10.47391/jpma-bagh-16-39","pdf_url":null,"source":{"id":"https://openalex.org/S26751084","display_name":"Journal of the Pakistan Medical Association","issn_l":"0030-9982","issn":["0030-9982"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","dongbi-d","medline","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4320800574","host_organization_name":"Pakistan Medical Association","host_organization_lineage":["https://openalex.org/P4320800574"],"host_organization_lineage_names":["Pakistan Medical Association"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Pakistan Medical Association","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1989964453","https://openalex.org/W3116781978","https://openalex.org/W2897700088","https://openalex.org/W7204134762","https://openalex.org/W2527463809","https://openalex.org/W3107876574","https://openalex.org/W3011678106","https://openalex.org/W4283776806","https://openalex.org/W4324046875","https://openalex.org/W2097191004"],"abstract_inverted_index":{"Objective:":[0],"To":[1],"find":[2],"the":[3,10,48,99,112,126,130,153,190,195],"relationship":[4],"between":[5],"vitamin":[6,66,183,206,213],"D":[7,67,184,207,214],"deficiency":[8,208],"and":[9,36,45,64,83,93,123,135,161,182,211],"activity":[11,73,80,85],"of":[12,43,54,143,157,169,174],"systemic":[13,38],"lupus":[14,39,200],"erythematosus":[15,40,201],"in":[16,117,121,125,189],"Iraqi":[17],"patients.":[18],"METHODS:":[19],"The":[20,145,171],"case-control":[21],"study":[22],"was":[23,103,149],"conducted":[24],"at":[25],"Baghdad":[26],"Teaching":[27],"Hospital,":[28],"Baghdad,":[29],"Iraq,":[30],"from":[31,204],"July":[32],"to":[33,194,219],"October":[34],"2018,":[35],"comprised":[37],"patients":[41,75,202],"regardless":[42],"age":[44,92,147,167],"gender":[46,94],"visiting":[47],"Rheumatology":[49],"outpatient":[50],"clinic.":[51],"Serum":[52],"levels":[53,173,185,215],"complement":[55,58,176,179],"protein":[56,59,177,180],"3,":[57,178],"4,":[60],"anti-doublestranded":[61],"deoxyribonucleic":[62],"acid":[63],"25-hydroxy":[65],"were":[68,76,95,116,133,137,186,216],"estimated.":[69],"Based":[70],"on":[71],"disease":[72,220],"scores,":[74],"divided":[77],"into":[78],"moderate":[79],"group":[81,86,155],"SLE-M":[82,122],"severe":[84],"SLE-S.":[87],"Healthy":[88],"subjects":[89],"matched":[90],"for":[91],"also":[96],"enrolled":[97],"as":[98],"control":[100,127,154],"group.":[101,128],"Data":[102],"analysed":[104],"using":[105],"Graph":[106],"Pad":[107],"Prism":[108],"5.0.":[109],"RESULTS:":[110],"Of":[111],"150":[113],"subjects,":[114],"62(41.3%)":[115],"SLE-S":[118],"group,":[119],"38(25.3%)":[120],"59(33.3%)":[124],"Among":[129],"patients,":[131],"97(97%)":[132],"females":[134,164],"3(3%)":[136],"males,":[138],"with":[139,165],"a":[140],"female-to-male":[141],"ratio":[142],"32:1.":[144],"patients'":[146],"range":[148,168],"<10-\u226550":[150],"years,":[151],"while":[152],"consisted":[156],"2":[158],"(4%)":[159],"males":[160],"48":[162],"(96%)":[163],"an":[166],"<10-\u226550.":[170],"mean":[172],"serum":[175],"4":[181],"significantly":[187],"lower":[188],"patient":[191],"groups":[192],"compared":[193],"controls":[196],"(p<0.05).":[197],"CONCLUSIONS:":[198],"Systemic":[199],"suffered":[203],"either":[205],"or":[209],"insufficiency,":[210],"low":[212],"found":[217],"related":[218],"activity.":[221]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2024-10-09T00:00:00"}