{"id":"https://openalex.org/W4403213089","doi":"https://doi.org/10.1371/journal.pone.0309314","title":"Hepatitis B infection: Evaluation of demographics and treatment of chronic hepatitis B infection in Northern-western Tanzania","display_name":"Hepatitis B infection: Evaluation of demographics and treatment of chronic hepatitis B infection in Northern-western Tanzania","publication_year":2024,"publication_date":"2024-10-08","ids":{"openalex":"https://openalex.org/W4403213089","doi":"https://doi.org/10.1371/journal.pone.0309314","pmid":"https://pubmed.ncbi.nlm.nih.gov/39378209","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11460692"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0309314","doi":"https://doi.org/10.1371/journal.pone.0309314","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0309314","pdf_url":null,"source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1371/journal.pone.0309314","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091069830","display_name":"Mathias Mlewa","orcid":"https://orcid.org/0009-0009-7432-8723","observed_orcids":["https://orcid.org/0009-0009-7432-8723"]},"institutions":[{"id":"https://openalex.org/I273065767","display_name":"Catholic University of Health and Allied Sciences","ror":"https://ror.org/015qmyq14","country_code":"TZ","type":"education","lineage":["https://openalex.org/I273065767"]},{"id":"https://openalex.org/I4388482664","display_name":"Mwanza University","ror":"https://ror.org/013t3qe76","country_code":"TZ","type":"education","lineage":["https://openalex.org/I4388482664"]}],"countries":["TZ"],"is_corresponding":true,"raw_author_name":"Mathias Mlewa","raw_affiliation_strings":["Department of Microbiology and Immunology, Catholic University of Health, and Allied Sciences, Mwanza, Tanzania","Department of Microbiology and Immunology, Mwanza University, Mwanza, Tanzania"],"raw_orcid":"https://orcid.org/0009-0009-7432-8723","affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Catholic University of Health, and Allied Sciences, Mwanza, Tanzania","institution_ids":["https://openalex.org/I273065767"]},{"raw_affiliation_string":"Department of Microbiology and Immunology, Mwanza University, Mwanza, Tanzania","institution_ids":["https://openalex.org/I4388482664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053510793","display_name":"Helmut A. Nyawale","orcid":"https://orcid.org/0000-0001-6916-6859","observed_orcids":["https://orcid.org/0000-0001-6916-6859"]},"institutions":[{"id":"https://openalex.org/I273065767","display_name":"Catholic University of Health and Allied Sciences","ror":"https://ror.org/015qmyq14","country_code":"TZ","type":"education","lineage":["https://openalex.org/I273065767"]}],"countries":["TZ"],"is_corresponding":false,"raw_author_name":"Helmut A. Nyawale","raw_affiliation_strings":["Department of Microbiology and Immunology, Catholic University of Health, and Allied Sciences, Mwanza, Tanzania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Catholic University of Health, and Allied Sciences, Mwanza, Tanzania","institution_ids":["https://openalex.org/I273065767"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031749650","display_name":"Shimba Henerico","orcid":"https://orcid.org/0000-0003-3659-0615","observed_orcids":["https://orcid.org/0000-0003-3659-0615"]},"institutions":[{"id":"https://openalex.org/I4210148991","display_name":"Bugando Medical Centre","ror":"https://ror.org/05h7pem82","country_code":"TZ","type":"healthcare","lineage":["https://openalex.org/I4210148991"]}],"countries":["TZ"],"is_corresponding":false,"raw_author_name":"Shimba Henerico","raw_affiliation_strings":["Department of Central Pathology Laboratory, Molecular Biology Laboratory, Bugando Medical Centre, Mwanza, Tanzania"],"raw_orcid":"https://orcid.org/0000-0003-3659-0615","affiliations":[{"raw_affiliation_string":"Department of Central Pathology Laboratory, Molecular Biology Laboratory, Bugando Medical Centre, Mwanza, Tanzania","institution_ids":["https://openalex.org/I4210148991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093623972","display_name":"Ivon Mangowi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148991","display_name":"Bugando Medical Centre","ror":"https://ror.org/05h7pem82","country_code":"TZ","type":"healthcare","lineage":["https://openalex.org/I4210148991"]}],"countries":["TZ"],"is_corresponding":false,"raw_author_name":"Ivon Mangowi","raw_affiliation_strings":["Department of Central Pathology Laboratory, Molecular Biology Laboratory, Bugando Medical Centre, Mwanza, Tanzania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Central Pathology Laboratory, Molecular Biology Laboratory, Bugando Medical Centre, Mwanza, Tanzania","institution_ids":["https://openalex.org/I4210148991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008847723","display_name":"Aminiel Robert Shangali","orcid":"https://orcid.org/0000-0002-3387-6514","observed_orcids":["https://orcid.org/0000-0002-3387-6514"]},"institutions":[{"id":"https://openalex.org/I4388482664","display_name":"Mwanza University","ror":"https://ror.org/013t3qe76","country_code":"TZ","type":"education","lineage":["https://openalex.org/I4388482664"]}],"countries":["TZ"],"is_corresponding":false,"raw_author_name":"Aminiel Robert Shangali","raw_affiliation_strings":["Department of Microbiology and Immunology, Mwanza University, Mwanza, Tanzania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Mwanza University, Mwanza, Tanzania","institution_ids":["https://openalex.org/I4388482664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085355458","display_name":"Anselmo Mathias Manisha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4388482664","display_name":"Mwanza University","ror":"https://ror.org/013t3qe76","country_code":"TZ","type":"education","lineage":["https://openalex.org/I4388482664"]}],"countries":["TZ"],"is_corresponding":false,"raw_author_name":"Anselmo Mathias Manisha","raw_affiliation_strings":["Department of Biochemistry and Molecular biology, Mwanza University, Mwanza, Tanzania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular biology, Mwanza University, Mwanza, Tanzania","institution_ids":["https://openalex.org/I4388482664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006026658","display_name":"Felix Kisanga","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4388482664","display_name":"Mwanza University","ror":"https://ror.org/013t3qe76","country_code":"TZ","type":"education","lineage":["https://openalex.org/I4388482664"]}],"countries":["TZ"],"is_corresponding":false,"raw_author_name":"Felix Kisanga","raw_affiliation_strings":["Department of Public Health, Mwanza University, Mwanza, Tanzania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Public Health, Mwanza University, Mwanza, Tanzania","institution_ids":["https://openalex.org/I4388482664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086760804","display_name":"Benson Richard Kidenya","orcid":"https://orcid.org/0000-0001-6056-4156","observed_orcids":["https://orcid.org/0000-0001-6056-4156"]},"institutions":[{"id":"https://openalex.org/I273065767","display_name":"Catholic University of Health and Allied Sciences","ror":"https://ror.org/015qmyq14","country_code":"TZ","type":"education","lineage":["https://openalex.org/I273065767"]}],"countries":["TZ"],"is_corresponding":false,"raw_author_name":"Benson R. Kidenya","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Catholic University of Health, and Allied Sciences, Mwanza, Tanzania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Catholic University of Health, and Allied Sciences, Mwanza, Tanzania","institution_ids":["https://openalex.org/I273065767"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059032743","display_name":"Hyasinta Jaka","orcid":"https://orcid.org/0000-0001-8712-7976","observed_orcids":["https://orcid.org/0000-0001-8712-7976"]},"institutions":[{"id":"https://openalex.org/I273065767","display_name":"Catholic University of Health and Allied Sciences","ror":"https://ror.org/015qmyq14","country_code":"TZ","type":"education","lineage":["https://openalex.org/I273065767"]},{"id":"https://openalex.org/I4210148991","display_name":"Bugando Medical Centre","ror":"https://ror.org/05h7pem82","country_code":"TZ","type":"healthcare","lineage":["https://openalex.org/I4210148991"]}],"countries":["TZ"],"is_corresponding":false,"raw_author_name":"Hyasinta Jaka","raw_affiliation_strings":["Department of Gastroenterology, Bugando Medical Centre, Mwanza, Tanzania","Department of Internal Medicine, Catholic University of Health, and Allied Sciences, Mwanza, Tanzania"],"raw_orcid":"https://orcid.org/0000-0001-8712-7976","affiliations":[{"raw_affiliation_string":"Department of Gastroenterology, Bugando Medical Centre, Mwanza, Tanzania","institution_ids":["https://openalex.org/I4210148991"]},{"raw_affiliation_string":"Department of Internal Medicine, Catholic University of Health, and Allied Sciences, Mwanza, Tanzania","institution_ids":["https://openalex.org/I273065767"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065710329","display_name":"Semvua Bukheti Kilonzo","orcid":"https://orcid.org/0000-0003-1197-9368","observed_orcids":["https://orcid.org/0000-0003-1197-9368"]},"institutions":[{"id":"https://openalex.org/I273065767","display_name":"Catholic University of Health and Allied Sciences","ror":"https://ror.org/015qmyq14","country_code":"TZ","type":"education","lineage":["https://openalex.org/I273065767"]}],"countries":["TZ"],"is_corresponding":false,"raw_author_name":"Semvua B. Kilonzo","raw_affiliation_strings":["Department of Internal Medicine, Catholic University of Health, and Allied Sciences, Mwanza, Tanzania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Catholic University of Health, and Allied Sciences, Mwanza, Tanzania","institution_ids":["https://openalex.org/I273065767"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017251518","display_name":"Mariam M. Mirambo","orcid":"https://orcid.org/0000-0003-2313-3079","observed_orcids":["https://orcid.org/0000-0003-2313-3079"]},"institutions":[{"id":"https://openalex.org/I273065767","display_name":"Catholic University of Health and Allied Sciences","ror":"https://ror.org/015qmyq14","country_code":"TZ","type":"education","lineage":["https://openalex.org/I273065767"]}],"countries":["TZ"],"is_corresponding":false,"raw_author_name":"Mariam M. Mirambo","raw_affiliation_strings":["Department of Microbiology and Immunology, Catholic University of Health, and Allied Sciences, Mwanza, Tanzania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Catholic University of Health, and Allied Sciences, Mwanza, Tanzania","institution_ids":["https://openalex.org/I273065767"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082060037","display_name":"Stephen Eliatosha Mshana","orcid":"https://orcid.org/0000-0002-7526-6271","observed_orcids":["https://orcid.org/0000-0002-7526-6271"]},"institutions":[{"id":"https://openalex.org/I273065767","display_name":"Catholic University of Health and Allied Sciences","ror":"https://ror.org/015qmyq14","country_code":"TZ","type":"education","lineage":["https://openalex.org/I273065767"]}],"countries":["TZ"],"is_corresponding":false,"raw_author_name":"Stephen E. Mshana","raw_affiliation_strings":["Department of Microbiology and Immunology, Catholic University of Health, and Allied Sciences, Mwanza, Tanzania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Catholic University of Health, and Allied Sciences, Mwanza, Tanzania","institution_ids":["https://openalex.org/I273065767"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5091069830"],"corresponding_institution_ids":["https://openalex.org/I273065767","https://openalex.org/I4388482664"],"apc_list":{"value":2290,"currency":"USD","value_usd":2290},"apc_paid":{"value":2290,"currency":"USD","value_usd":2290},"fwci":0.2655,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.47373685,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"19","issue":"10","first_page":"e0309314","last_page":"e0309314"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10340","display_name":"Hepatitis B Virus Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10340","display_name":"Hepatitis B Virus Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-hepatitis-b","display_name":"chronic hepatitis B","score":0.9869999885559082},{"id":"https://openalex.org/keywords/hepatitis-b-virus","display_name":"hepatitis B virus","score":0.8820000290870667},{"id":"https://openalex.org/keywords/treatment-eligibility","display_name":"treatment eligibility","score":0.781000018119812},{"id":"https://openalex.org/keywords/hbv-viral-load","display_name":"HBV DNA viral load","score":0.5569999814033508},{"id":"https://openalex.org/keywords/liver-fibrosis","display_name":"liver fibrosis","score":0.8379999995231628},{"id":"https://openalex.org/keywords/apri","display_name":"APRI","score":0.6919999718666077},{"id":"https://openalex.org/keywords/fib-4-index","display_name":"FIB-4","score":0.9789999723434448},{"id":"https://openalex.org/keywords/sociodemographic-factors","display_name":"sociodemographic factors","score":0.7200000286102295},{"id":"https://openalex.org/keywords/tanzania","display_name":"Tanzania","score":0.3580000102519989}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8511042594909668},{"id":"https://openalex.org/C2779357621","wikidata":"https://www.wikidata.org/wiki/Q655495","display_name":"Tanzania","level":2,"score":0.5680566430091858},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5619955062866211},{"id":"https://openalex.org/C2777382497","wikidata":"https://www.wikidata.org/wiki/Q6853","display_name":"Hepatitis B","level":2,"score":0.5318357944488525},{"id":"https://openalex.org/C2780593183","wikidata":"https://www.wikidata.org/wiki/Q6844","display_name":"Hepatitis B virus","level":3,"score":0.5147995352745056},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.48699837923049927},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3092392086982727},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.18922990560531616},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.16385123133659363},{"id":"https://openalex.org/C91375879","wikidata":"https://www.wikidata.org/wiki/Q15473274","display_name":"Environmental planning","level":1,"score":0.0},{"id":"https://openalex.org/C39432304","wikidata":"https://www.wikidata.org/wiki/Q188847","display_name":"Environmental science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006515","descriptor_name":"Hepatitis B virus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013636","descriptor_name":"Tanzania","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D019562","descriptor_name":"Viral Load","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019694","descriptor_name":"Hepatitis B, Chronic","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D019694","descriptor_name":"Hepatitis B, Chronic","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D019694","descriptor_name":"Hepatitis B, Chronic","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1371/journal.pone.0309314","doi":"https://doi.org/10.1371/journal.pone.0309314","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0309314","pdf_url":null,"source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11460692","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11460692","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11460692/pdf/pone.0309314.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmid:39378209","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39378209","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:b8fdf9b837ce43c28bf94cbca3ded383","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/b8fdf9b837ce43c28bf94cbca3ded383","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 19, Iss 10, p e0309314 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0309314","doi":"https://doi.org/10.1371/journal.pone.0309314","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0309314","pdf_url":null,"source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"},{"score":0.4000000059604645,"id":"https://metadata.un.org/sdg/10","display_name":"Reduced inequalities"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4403213089.pdf","grobid_xml":"https://content.openalex.org/works/W4403213089.grobid-xml"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W1868509006","https://openalex.org/W1880528783","https://openalex.org/W1924609143","https://openalex.org/W1993066984","https://openalex.org/W2004100607","https://openalex.org/W2021264347","https://openalex.org/W2057002646","https://openalex.org/W2062521835","https://openalex.org/W2081764223","https://openalex.org/W2104389844","https://openalex.org/W2115826876","https://openalex.org/W2139377426","https://openalex.org/W2144531987","https://openalex.org/W2146353434","https://openalex.org/W2173855355","https://openalex.org/W2189009687","https://openalex.org/W2281859527","https://openalex.org/W2314866596","https://openalex.org/W2319897007","https://openalex.org/W2330766419","https://openalex.org/W2605785536","https://openalex.org/W2618921796","https://openalex.org/W2788473137","https://openalex.org/W2792219205","https://openalex.org/W2860439419","https://openalex.org/W2985605496","https://openalex.org/W3000497104","https://openalex.org/W3033274669","https://openalex.org/W3176081318","https://openalex.org/W3197679487","https://openalex.org/W3199079759","https://openalex.org/W4223456336","https://openalex.org/W4281696197","https://openalex.org/W4296628527","https://openalex.org/W4306677256","https://openalex.org/W4313706725","https://openalex.org/W4360946379","https://openalex.org/W4367181679","https://openalex.org/W4379230426","https://openalex.org/W4387166818","https://openalex.org/W4387942506"],"related_works":["https://openalex.org/W4387942506","https://openalex.org/W4416098706","https://openalex.org/W3000497104","https://openalex.org/W4413908180","https://openalex.org/W2803539108","https://openalex.org/W112021067","https://openalex.org/W4401750757","https://openalex.org/W4383872843","https://openalex.org/W2897885884","https://openalex.org/W6957672546"],"abstract_inverted_index":{"BACKGROUND:":[0],"Chronic":[1],"hepatitis":[2],"B":[3],"virus":[4],"(HBV)":[5],"infection":[6,33,294],"is":[7],"still":[8],"a":[9],"major":[10],"public":[11],"health":[12],"problem.":[13],"In":[14],"response":[15],"to":[16,27,86,171,182],"the":[17,29,111,127,183,252,289],"World":[18],"Health":[19,115],"Organization":[20],"(WHO),":[21],"Tanzania":[22],"implemented":[23],"immunization":[24],"and":[25,48,60,94,99,106,116,123,126,138,148,152,163,177,189,196,274],"treatment":[26],"achieve":[28,37],"eradication":[30],"of":[31,42,114,255],"HBV":[32,80,153,186,293],"by":[34,110,278,288,295],"2030.":[35,296],"To":[36],"this":[38],"goal,":[39],"frequent":[40],"updates":[41],"demographic":[43,55],"data,":[44,56],"antiviral":[45,57,237],"therapy":[46,58,238,281],"eligibility,":[47,59],"uptake":[49,61,178,243,282],"are":[50],"essential.":[51],"We":[52],"therefore":[53],"evaluated":[54,180],"among":[62],"chronically":[63,262],"HBV-infected":[64,263],"patients":[65,81,96,208,264],"attending":[66,265],"at":[67,90,266],"Bugando":[68,128],"Medical":[69,119,129],"Centre":[70,120,130],"(BMC),":[71],"Tanzania.":[72],"METHODS:":[73],"A":[74],"cross-sectional":[75],"study":[76,216],"enrolled":[77],"196":[78],"chronic":[79],"from":[82],"April":[83],"23,":[84],"2023,":[85,89],"October":[87],"10,":[88],"BMC,":[91],"where":[92],"100":[93],"96":[95],"were":[97,108,142,157,168,179,194,220,268,275],"retrospectively":[98],"prospectively":[100],"enrolled,":[101],"respectively.":[102,132],"Study's":[103],"ethical":[104],"clearance":[105],"permission":[107],"observed":[109],"Catholic":[112],"University":[113],"Allied":[117],"Sciences/Bugando":[118],"research":[121],"ethics":[122],"review":[124],"committee":[125],"management":[131],"For":[133],"all":[134,207,215,261],"patients,":[135,217],"socio-demographic":[136],"data":[137,193],"whole":[139],"blood":[140,145],"samples":[141],"obtained.":[143],"Full":[144],"picture,":[146],"alanine":[147],"aspartate":[149],"amino":[150],"transferases,":[151],"viral":[154],"load":[155],"parameters":[156],"determined.":[158],"Aspartate-Platelet":[159],"Ratio":[160],"Index":[161],"(APRI)":[162],"Fibrosis":[164],"Four":[165],"(FIB-4)":[166],"scores":[167],"calculated":[169],"according":[170,181],"their":[172],"respective":[173],"formulas.":[174],"Therapy":[175],"eligibility":[176,239],"2015":[184],"WHO":[185,253,290],"prevention,":[187],"treatment,":[188],"care":[190],"guidelines.":[191],"The":[192,203],"summarized":[195],"analysed":[197],"using":[198],"STATA":[199],"version":[200],"15.":[201],"RESULTS:":[202],"median":[204],"age":[205],"for":[206],"was":[209,240,244,248,283],"39":[210],"[IQR:":[211],"32-47.5]":[212],"years.":[213],"Nearly":[214],"99%":[218],"(194/196),":[219],"older":[221,269],"than":[222,251,270,286],"20":[223,271],"years":[224,272],"old,":[225],"with":[226],"significant":[227],"male":[228],"dominance":[229],"(73.5%":[230],"[144/196]":[231],"versus":[232],"26.5%":[233],"[52/196];":[234],"p<0.0001).":[235],"Anti-HBV":[236],"22.4%,":[241],"while":[242],"6.8%":[245],"(3/4),":[246],"which":[247],"significantly":[249,276],"lower":[250,285],"expectation":[254],"80%":[256],"(p":[257],"<0.0001).":[258],"CONCLUSION:":[259],"Almost":[260],"BMC":[267],"old":[273],"dominated":[277],"males.":[279],"Antiviral":[280],"remarkably":[284],"expected":[287],"towards":[291],"combating":[292]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2024-10-09T00:00:00"}
