{"id":"https://openalex.org/W4403206350","doi":"https://doi.org/10.1007/s11250-024-04119-3","title":"In ovo betaine and heat acclimation affect hatching results, growth performance and immunity of the broilers under cyclic heat stress","display_name":"In ovo betaine and heat acclimation affect hatching results, growth performance and immunity of the broilers under cyclic heat stress","publication_year":2024,"publication_date":"2024-10-08","ids":{"openalex":"https://openalex.org/W4403206350","doi":"https://doi.org/10.1007/s11250-024-04119-3","pmid":"https://pubmed.ncbi.nlm.nih.gov/39378007"},"language":"en","primary_location":{"id":"doi:10.1007/s11250-024-04119-3","doi":"https://doi.org/10.1007/s11250-024-04119-3","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11250-024-04119-3","pdf_url":null,"source":{"id":"https://openalex.org/S153189382","display_name":"Tropical Animal Health and Production","issn_l":"0049-4747","issn":["0049-4747","1573-7438"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tropical Animal Health and Production","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://dx.doi.org/10.21203/rs.3.rs-4363380/v1","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089987692","display_name":"Mustafa Ak\u015fit","orcid":"https://orcid.org/0000-0002-8074-8208","observed_orcids":["https://orcid.org/0000-0002-8074-8208"]},"institutions":[{"id":"https://openalex.org/I76806599","display_name":"Adnan Menderes University","ror":"https://ror.org/03n7yzv56","country_code":"TR","type":"education","lineage":["https://openalex.org/I76806599"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Mustafa Ak\u015fit","raw_affiliation_strings":["Faculty of Agriculture, Department of Animal Science, Ayd\u0131n Adnan Menderes University, Ayd\u0131n, T\u00fcrkiye. maksit@adu.edu.tr"],"raw_orcid":"https://orcid.org/0000-0002-8074-8208","affiliations":[{"raw_affiliation_string":"Faculty of Agriculture, Department of Animal Science, Ayd\u0131n Adnan Menderes University, Ayd\u0131n, T\u00fcrkiye. maksit@adu.edu.tr","institution_ids":["https://openalex.org/I76806599"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046702723","display_name":"\u0130hsan B\u00fclent Helva","orcid":"https://orcid.org/0000-0001-8505-6481","observed_orcids":["https://orcid.org/0000-0001-8505-6481"]},"institutions":[{"id":"https://openalex.org/I76806599","display_name":"Adnan Menderes University","ror":"https://ror.org/03n7yzv56","country_code":"TR","type":"education","lineage":["https://openalex.org/I76806599"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"\u0130hsan B\u00fclent Helva","raw_affiliation_strings":["\u00c7ine Vocational High School, Ayd\u0131n Adnan Menderes University, \u00c7ine, Ayd\u0131n, T\u00fcrkiye"],"raw_orcid":"https://orcid.org/0000-0001-8505-6481","affiliations":[{"raw_affiliation_string":"\u00c7ine Vocational High School, Ayd\u0131n Adnan Menderes University, \u00c7ine, Ayd\u0131n, T\u00fcrkiye","institution_ids":["https://openalex.org/I76806599"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070937506","display_name":"Zeynep Yard\u0131m","orcid":"https://orcid.org/0000-0002-9235-3721","observed_orcids":["https://orcid.org/0000-0002-9235-3721"]},"institutions":[{"id":"https://openalex.org/I76806599","display_name":"Adnan Menderes University","ror":"https://ror.org/03n7yzv56","country_code":"TR","type":"education","lineage":["https://openalex.org/I76806599"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Zeynep Yard\u0131m","raw_affiliation_strings":["Faculty of Agriculture, Department of Animal Science, Ayd\u0131n Adnan Menderes University, Ayd\u0131n, T\u00fcrkiye"],"raw_orcid":"https://orcid.org/0000-0002-9235-3721","affiliations":[{"raw_affiliation_string":"Faculty of Agriculture, Department of Animal Science, Ayd\u0131n Adnan Menderes University, Ayd\u0131n, T\u00fcrkiye","institution_ids":["https://openalex.org/I76806599"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011220751","display_name":"S. Yal\u00e7\u0131n","orcid":"https://orcid.org/0000-0003-4194-0536","observed_orcids":["https://orcid.org/0000-0003-4194-0536"]},"institutions":[{"id":"https://openalex.org/I41641357","display_name":"Ege University","ror":"https://ror.org/02eaafc18","country_code":"TR","type":"education","lineage":["https://openalex.org/I41641357"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Servet Yal\u00e7\u0131n","raw_affiliation_strings":["Faculty of Agriculture, Department of Animal Science, Ege University, \u0130zmir, T\u00fcrkiye"],"raw_orcid":"https://orcid.org/0000-0003-4194-0536","affiliations":[{"raw_affiliation_string":"Faculty of Agriculture, Department of Animal Science, Ege University, \u0130zmir, T\u00fcrkiye","institution_ids":["https://openalex.org/I41641357"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5089987692"],"corresponding_institution_ids":["https://openalex.org/I76806599"],"apc_list":{"value":3790,"currency":"USD","value_usd":3790},"apc_paid":null,"fwci":0.2964,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.56286019,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"56","issue":"8","first_page":"330","last_page":"330"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10152","display_name":"Animal Nutrition and Physiology","score":0.7904999852180481,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10152","display_name":"Animal Nutrition and Physiology","score":0.7904999852180481,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12365","display_name":"Effects of Environmental Stressors on Livestock","score":0.20579999685287476,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11109","display_name":"Thermoregulation and physiological responses","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heat-acclimation","display_name":"heat acclimation","score":0.9710000157356262},{"id":"https://openalex.org/keywords/cyclic-heat-stress","display_name":"cyclic heat stress","score":0.9259999990463257},{"id":"https://openalex.org/keywords/broiler-chickens","display_name":"broiler chickens","score":0.878000020980835},{"id":"https://openalex.org/keywords/hatchability","display_name":"hatchability","score":0.7590000033378601},{"id":"https://openalex.org/keywords/growth-performance","display_name":"growth performance","score":0.9399999976158142},{"id":"https://openalex.org/keywords/feed-conversion-ratio","display_name":"feed conversion ratio","score":0.8360000252723694},{"id":"https://openalex.org/keywords/immune-function","display_name":"immune function","score":0.47600001096725464},{"id":"https://openalex.org/keywords/serum-igg","display_name":"serum IgG","score":0.8460000157356262},{"id":"https://openalex.org/keywords/thymus-weight","display_name":"thymus weight","score":0.9819999933242798},{"id":"https://openalex.org/keywords/spleen-weight","display_name":"spleen weight","score":0.8100000023841858},{"id":"https://openalex.org/keywords/rearing-temperature","display_name":"rearing temperature","score":0.7559999823570251},{"id":"https://openalex.org/keywords/serum-cholesterol","display_name":"serum cholesterol","score":0.4740000069141388}],"concepts":[{"id":"https://openalex.org/C2778765379","wikidata":"https://www.wikidata.org/wiki/Q17055931","display_name":"In ovo","level":3,"score":0.9919221997261047},{"id":"https://openalex.org/C25642318","wikidata":"https://www.wikidata.org/wiki/Q1992532","display_name":"Incubation","level":2,"score":0.8275189995765686},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6365201473236084},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.6260779500007629},{"id":"https://openalex.org/C2780289900","wikidata":"https://www.wikidata.org/wiki/Q326301","display_name":"Broiler","level":2,"score":0.5945388674736023},{"id":"https://openalex.org/C143701427","wikidata":"https://www.wikidata.org/wiki/Q193566","display_name":"Incubation period","level":3,"score":0.5710906982421875},{"id":"https://openalex.org/C22830521","wikidata":"https://www.wikidata.org/wiki/Q649967","display_name":"Feed conversion ratio","level":3,"score":0.5406913161277771},{"id":"https://openalex.org/C2777744765","wikidata":"https://www.wikidata.org/wiki/Q2734755","display_name":"Hatching","level":2,"score":0.5017008781433105},{"id":"https://openalex.org/C147583825","wikidata":"https://www.wikidata.org/wiki/Q620876","display_name":"Body weight","level":2,"score":0.33972108364105225},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.2143823802471161},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.17749541997909546},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16808193922042847},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000064","descriptor_name":"Acclimatization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001622","descriptor_name":"Betaine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D001622","descriptor_name":"Betaine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D002642","descriptor_name":"Chick Embryo","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002645","descriptor_name":"Chickens","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D002645","descriptor_name":"Chickens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D002645","descriptor_name":"Chickens","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006358","descriptor_name":"Hot Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010063","descriptor_name":"Ovum","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013950","descriptor_name":"Thymus Gland","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018869","descriptor_name":"Heat-Shock Response","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/s11250-024-04119-3","doi":"https://doi.org/10.1007/s11250-024-04119-3","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11250-024-04119-3","pdf_url":null,"source":{"id":"https://openalex.org/S153189382","display_name":"Tropical Animal Health and Production","issn_l":"0049-4747","issn":["0049-4747","1573-7438"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tropical Animal Health and Production","raw_type":"journal-article"},{"id":"doi:10.21203/rs.3.rs-4363380/v1","doi":"https://doi.org/10.21203/rs.3.rs-4363380/v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.21203/rs.3.rs-4363380/v1","pdf_url":null,"source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},{"id":"pmid:39378007","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39378007","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tropical animal health and production","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.21203/rs.3.rs-4363380/v1","doi":"https://doi.org/10.21203/rs.3.rs-4363380/v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.21203/rs.3.rs-4363380/v1","pdf_url":null,"source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.958299994468689,"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W1993678762","https://openalex.org/W1996718544","https://openalex.org/W2010285807","https://openalex.org/W2015548864","https://openalex.org/W2035855797","https://openalex.org/W2057476376","https://openalex.org/W2066666506","https://openalex.org/W2068971799","https://openalex.org/W2080942280","https://openalex.org/W2085886216","https://openalex.org/W2107431910","https://openalex.org/W2107651627","https://openalex.org/W2133016683","https://openalex.org/W2136738648","https://openalex.org/W2137552559","https://openalex.org/W2140521966","https://openalex.org/W2141285039","https://openalex.org/W2147502402","https://openalex.org/W2154952692","https://openalex.org/W2155905473","https://openalex.org/W2171996435","https://openalex.org/W2217933049","https://openalex.org/W2289638618","https://openalex.org/W2291948874","https://openalex.org/W2329837577","https://openalex.org/W2555322673","https://openalex.org/W2564848275","https://openalex.org/W2567154393","https://openalex.org/W2611162287","https://openalex.org/W2737430199","https://openalex.org/W2739926192","https://openalex.org/W2778533827","https://openalex.org/W2795154706","https://openalex.org/W2888137149","https://openalex.org/W2896486299","https://openalex.org/W2898200026","https://openalex.org/W2947995944","https://openalex.org/W2965007445","https://openalex.org/W2973124643","https://openalex.org/W2989818980","https://openalex.org/W2998002900","https://openalex.org/W3001575790","https://openalex.org/W3005061733","https://openalex.org/W3091897055","https://openalex.org/W3154379725","https://openalex.org/W3163003226","https://openalex.org/W3214124550","https://openalex.org/W4200174812","https://openalex.org/W4210433017","https://openalex.org/W4220797152","https://openalex.org/W4230116762","https://openalex.org/W4280599742","https://openalex.org/W4288067777","https://openalex.org/W4391822349","https://openalex.org/W4396574705"],"related_works":["https://openalex.org/W4400550739","https://openalex.org/W2291948874","https://openalex.org/W3183297072","https://openalex.org/W3005061733","https://openalex.org/W4321253989","https://openalex.org/W4391822349","https://openalex.org/W7219404752","https://openalex.org/W7217267265","https://openalex.org/W6901642274","https://openalex.org/W2564848275"],"abstract_inverted_index":{"Abstract":[0],"This":[1],"study":[2],"was":[3,45,126,135,200],"conducted":[4],"to":[5,70,86,188,225],"investigate":[6],"the":[7,77,145],"effect":[8],"of":[9,26,53,66,73,76,109,112,118,149,242,249],"in":[10,128],"ovo":[11],"betaine":[12],"(IOB)":[13],"and":[14,22,39,96,106,115,142,157,170,181,217,233,239,245],"thermal":[15],"manipulation":[16],"during":[17],"incubation":[18,54,81],"on":[19,174,198,215],"growth":[20],"performance,":[21],"some":[23],"immune":[24],"parameters":[25],"broilers":[27],"under":[28,36,59,251],"cyclic":[29],"heat":[30,40],"stress":[31],"(CHS).":[32],"Eggs":[33],"were":[34,57,84,90,161,206],"incubated":[35],"control":[37],"(CL)":[38],"acclimation":[41],"(HA)":[42],"conditions.":[43],"Betaine":[44],"injected":[46],"into":[47],"chicken":[48],"embryos":[49],"at":[50,92],"day":[51],"11":[52],"(E11).":[55],"Chicks":[56],"raised":[58],"standard":[60],"management":[61],"conditions":[62],"until":[63],"21":[64,69,143,189],"d":[65,72],"age.":[67],"From":[68],"42":[71,226],"age,":[74],"half":[75],"birds":[78,250],"from":[79,151,186,223],"each":[80],"treatment":[82],"(IT)":[83],"exposed":[85],"CHS.":[87,252],"The":[88,123],"others":[89],"kept":[91],"24\u00b0C":[93],"(OPT).":[94],"Betain":[95,176,219],"HA":[97,129,232],"did":[98],"not":[99,136],"affect":[100],"embryonic":[101],"mortalities,":[102],"hatchability,":[103],"chick":[104],"weight,":[105],"relative":[107],"weights":[108,117,147],"digestive":[110],"organs":[111],"chicks.":[113,132],"Thymus":[114],"spleen":[116],"chicks":[119,150,244],"increased":[120,177],"with":[121],"betain.":[122],"serum":[124],"IgG":[125,240],"higher":[127],"+":[130],"IOB-treated":[131],"Blood":[133],"cholesterol":[134],"influenced":[137],"by":[138],"treatments.":[139],"At":[140,155,191,202],"7":[141],"d,":[144,159,193,204],"body":[146],"(BW)":[148],"IOB":[152,171,212,234],"had":[153],"heavier.":[154],"28":[156,192],"35":[158,203],"there":[160,205],"significant":[162,207],"interaction":[163,197],"between":[164],"IT":[165,194,210],"\u00d7":[166,172,195,211,213],"rearing":[167],"temperature":[168],"(RT)":[169],"RT":[173,196,214],"BW.":[175],"feed":[178,183],"consumption":[179],"(FC)":[180],"improved":[182,221],"conversion":[184],"(FCR)":[185],"0":[187,224],"d.":[190,227],"FC":[199,216],"significant.":[201],"interactions":[208],"among":[209],"FCR.":[218],"slightly":[220],"FCR":[222],"These":[228],"results":[229],"indicated":[230],"that":[231],"positively":[235],"affected":[236],"thymus":[237],"weight":[238],"level":[241],"day-old":[243],"enhanced":[246],"broiler":[247],"performance":[248]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2024-10-09T00:00:00"}