{"id":"https://openalex.org/W4403172378","doi":"https://doi.org/10.1039/d4cc03578j","title":"Progress and limitations in reactive oxygen species quantitation","display_name":"Progress and limitations in reactive oxygen species quantitation","publication_year":2024,"publication_date":"2024-01-01","ids":{"openalex":"https://openalex.org/W4403172378","doi":"https://doi.org/10.1039/d4cc03578j","pmid":"https://pubmed.ncbi.nlm.nih.gov/39373601"},"language":"en","primary_location":{"id":"doi:10.1039/d4cc03578j","doi":"https://doi.org/10.1039/d4cc03578j","is_oa":false,"landing_page_url":"https://doi.org/10.1039/d4cc03578j","pdf_url":null,"source":{"id":"https://openalex.org/S152760256","display_name":"Chemical Communications","issn_l":"1359-7345","issn":["1359-7345","1364-548X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-2","ki-jl-1","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical Communications","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037741673","display_name":"Eleni M. Spanolios","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eleni M. Spanolios","raw_affiliation_strings":["University of Minnesota \u2013 Twin Cities, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Minnesota \u2013 Twin Cities, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005047153","display_name":"Riley E. Lewis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Riley E. Lewis","raw_affiliation_strings":["University of Minnesota \u2013 Twin Cities, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Minnesota \u2013 Twin Cities, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Rhea N. Caldwell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rhea N. Caldwell","raw_affiliation_strings":["University of Minnesota \u2013 Twin Cities, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Minnesota \u2013 Twin Cities, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086700566","display_name":"Safia Z. Jilani","orcid":"https://orcid.org/0000-0002-3545-1878","observed_orcids":["https://orcid.org/0000-0002-3545-1878"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Safia Z. Jilani","raw_affiliation_strings":["University of Minnesota \u2013 Twin Cities, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Minnesota \u2013 Twin Cities, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051055962","display_name":"Christy L. Haynes","orcid":"https://orcid.org/0000-0002-5420-5867","observed_orcids":["https://orcid.org/0000-0002-5420-5867"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Christy L. Haynes","raw_affiliation_strings":["University of Minnesota \u2013 Twin Cities, USA"],"raw_orcid":"https://orcid.org/0000-0002-5420-5867","affiliations":[{"raw_affiliation_string":"University of Minnesota \u2013 Twin Cities, USA","institution_ids":["https://openalex.org/I130238516"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5051055962"],"corresponding_institution_ids":["https://openalex.org/I130238516"],"apc_list":null,"apc_paid":null,"fwci":0.7744,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.63466391,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"60","issue":"86","first_page":"12487","last_page":"12501"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.7182999849319458,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.7182999849319458,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10532","display_name":"Molecular Sensors and Ion Detection","score":0.10849999636411667,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.03139999881386757,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.9990000128746033},{"id":"https://openalex.org/keywords/fluorescence-detection","display_name":"fluorescence detection","score":0.8700000047683716},{"id":"https://openalex.org/keywords/electrochemical-detection","display_name":"electrochemical detection","score":0.9430000185966492},{"id":"https://openalex.org/keywords/electron-spin-resonance","display_name":"electron spin resonance","score":0.9100000262260437},{"id":"https://openalex.org/keywords/cellular-stress","display_name":"cellular stress","score":0.45899999141693115},{"id":"https://openalex.org/keywords/oxidative-damage","display_name":"oxidative damage","score":0.5960000157356262},{"id":"https://openalex.org/keywords/water-purification","display_name":"water purification","score":0.859000027179718},{"id":"https://openalex.org/keywords/high-spatiotemporal-resolution","display_name":"high spatial and temporal resolution","score":0.7609999775886536}],"concepts":[{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.8666961193084717},{"id":"https://openalex.org/C2910908493","wikidata":"https://www.wikidata.org/wiki/Q260463","display_name":"Electron paramagnetic resonance spectroscopy","level":3,"score":0.6611789464950562},{"id":"https://openalex.org/C187961010","wikidata":"https://www.wikidata.org/wiki/Q260463","display_name":"Electron paramagnetic resonance","level":2,"score":0.5884203314781189},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.5879442691802979},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5577133297920227},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.4119575619697571},{"id":"https://openalex.org/C75473681","wikidata":"https://www.wikidata.org/wiki/Q188651","display_name":"Photochemistry","level":1,"score":0.34618616104125977},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.22087916731834412},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.12232258915901184},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0985555350780487},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004578","descriptor_name":"Electron Spin Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D055664","descriptor_name":"Electrochemical Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1039/d4cc03578j","doi":"https://doi.org/10.1039/d4cc03578j","is_oa":false,"landing_page_url":"https://doi.org/10.1039/d4cc03578j","pdf_url":null,"source":{"id":"https://openalex.org/S152760256","display_name":"Chemical Communications","issn_l":"1359-7345","issn":["1359-7345","1364-548X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-2","ki-jl-1","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical Communications","raw_type":"journal-article"},{"id":"pmid:39373601","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39373601","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical communications (Cambridge, England)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G568619150","display_name":"NSF Center for Sustainable Nanotechnology","funder_award_id":"2001611","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":106,"referenced_works":["https://openalex.org/W1518991754","https://openalex.org/W1566903199","https://openalex.org/W1963907102","https://openalex.org/W1983203947","https://openalex.org/W1997684038","https://openalex.org/W1999093820","https://openalex.org/W2010154445","https://openalex.org/W2013322023","https://openalex.org/W2015652178","https://openalex.org/W2016292169","https://openalex.org/W2030363360","https://openalex.org/W2043525368","https://openalex.org/W2046096000","https://openalex.org/W2050264954","https://openalex.org/W2052208079","https://openalex.org/W2064450459","https://openalex.org/W2080843596","https://openalex.org/W2084326249","https://openalex.org/W2114467922","https://openalex.org/W2117040358","https://openalex.org/W2118489870","https://openalex.org/W2121406617","https://openalex.org/W2131941687","https://openalex.org/W2150822249","https://openalex.org/W2168961368","https://openalex.org/W2243993274","https://openalex.org/W2273545466","https://openalex.org/W2315427585","https://openalex.org/W2327845453","https://openalex.org/W2338274451","https://openalex.org/W2341788744","https://openalex.org/W2351269335","https://openalex.org/W2408338999","https://openalex.org/W2514279849","https://openalex.org/W2515239417","https://openalex.org/W2530909141","https://openalex.org/W2591825861","https://openalex.org/W2608127197","https://openalex.org/W2727345969","https://openalex.org/W2728985030","https://openalex.org/W2744078894","https://openalex.org/W2749694032","https://openalex.org/W2763434265","https://openalex.org/W2765559067","https://openalex.org/W2766085136","https://openalex.org/W2769163423","https://openalex.org/W2775756217","https://openalex.org/W2779360678","https://openalex.org/W2783085570","https://openalex.org/W2789207181","https://openalex.org/W2889535292","https://openalex.org/W2889556862","https://openalex.org/W2891589914","https://openalex.org/W2895889294","https://openalex.org/W2898110990","https://openalex.org/W2899112900","https://openalex.org/W2902203788","https://openalex.org/W2903057908","https://openalex.org/W2912624995","https://openalex.org/W2963601492","https://openalex.org/W2964609569","https://openalex.org/W2971142863","https://openalex.org/W2988419181","https://openalex.org/W2990274398","https://openalex.org/W2996462413","https://openalex.org/W2997601619","https://openalex.org/W3019293267","https://openalex.org/W3023273411","https://openalex.org/W3027731243","https://openalex.org/W3028148512","https://openalex.org/W3036702903","https://openalex.org/W3065911199","https://openalex.org/W3087475200","https://openalex.org/W3106689433","https://openalex.org/W3110770877","https://openalex.org/W3116389315","https://openalex.org/W3120280554","https://openalex.org/W3127478233","https://openalex.org/W3137737171","https://openalex.org/W3154407685","https://openalex.org/W3175687295","https://openalex.org/W3215450900","https://openalex.org/W4200491802","https://openalex.org/W4206693824","https://openalex.org/W4210245399","https://openalex.org/W4281571211","https://openalex.org/W4283575177","https://openalex.org/W4283701282","https://openalex.org/W4283817749","https://openalex.org/W4286561783","https://openalex.org/W4297093498","https://openalex.org/W4312226010","https://openalex.org/W4327518885","https://openalex.org/W4365514881","https://openalex.org/W4377009114","https://openalex.org/W4380449756","https://openalex.org/W4380875575","https://openalex.org/W4387021043","https://openalex.org/W4387959358","https://openalex.org/W4389304901","https://openalex.org/W4390667437","https://openalex.org/W4391475090","https://openalex.org/W4392155684","https://openalex.org/W4392798785","https://openalex.org/W4400955360","https://openalex.org/W4401107600"],"related_works":["https://openalex.org/W4408920612","https://openalex.org/W3124132383","https://openalex.org/W3207018718","https://openalex.org/W2043074688","https://openalex.org/W1981826336","https://openalex.org/W2482577988","https://openalex.org/W2063304359","https://openalex.org/W298296732","https://openalex.org/W2793074923","https://openalex.org/W1986371885"],"abstract_inverted_index":{"Reactive":[0],"oxygen":[1],"species":[2],"(ROS)":[3],"are":[4,13,44],"a":[5,16,74],"set":[6],"of":[7,19,30,57,62,66,76,84,129,137,149],"oxygen-":[8],"and":[9,38,82,104,107,127,132],"nitrogen-containing":[10],"radicals.":[11],"They":[12],"produced":[14],"from":[15,92],"wide":[17],"range":[18,75],"sources.":[20],"In":[21,41],"biological":[22],"contexts,":[23],"cellular":[24],"stress":[25],"leads":[26],"to":[27,35,90,95],"an":[28,58,70],"overproduction":[29],"ROS,":[31],"which":[32],"can":[33,114],"lead":[34],"genetic":[36],"damage":[37],"disease":[39],"development.":[40],"industry,":[42],"ROS":[43,67,85,119,138],"often":[45],"productively":[46],"used":[47],"for":[48,52,146],"water":[49],"purification":[50],"or":[51],"analyzing":[53],"the":[54,124,140,147,150],"possible":[55],"toxicity":[56],"industrial":[59],"process.":[60],"Because":[61],"their":[63],"ubiquity,":[64],"detection":[65,94,111,136],"has":[68],"been":[69],"analytical":[71],"goal":[72],"across":[73],"fields.":[77],"To":[78],"understand":[79],"complicated":[80],"systems":[81],"origins":[83],"production,":[86],"it":[87],"is":[88],"necessary":[89],"move":[91],"qualitative":[93],"quantitation.":[96],"Analytical":[97],"techniques":[98],"that":[99,113],"combine":[100],"quantitation,":[101],"high":[102],"spatial":[103],"temporal":[105],"resolution,":[106],"good":[108],"specificity":[109],"represent":[110],"methods":[112],"fill":[115],"critical":[116],"gaps":[117],"in":[118],"research.":[120],"Herein,":[121],"we":[122],"discuss":[123],"continued":[125],"progress":[126],"limitations":[128],"fluorescence,":[130],"electrochemical,":[131],"electron":[133],"paramagnetic":[134],"resonance":[135],"over":[139],"last":[141],"ten":[142],"years,":[143],"giving":[144],"suggestions":[145],"future":[148],"field.":[151]},"counts_by_year":[{"year":2026,"cited_by_count":14},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2024-10-07T00:00:00"}
