{"id":"https://openalex.org/W4403051637","doi":"https://doi.org/10.7554/elife.73832","title":"Temporal transcriptional response of Candida glabrata during macrophage infection reveals a multifaceted transcriptional regulator CgXbp1 important for macrophage response and fluconazole resistance","display_name":"Temporal transcriptional response of Candida glabrata during macrophage infection reveals a multifaceted transcriptional regulator CgXbp1 important for macrophage response and fluconazole resistance","publication_year":2024,"publication_date":"2024-10-02","ids":{"openalex":"https://openalex.org/W4403051637","doi":"https://doi.org/10.7554/elife.73832","pmid":"https://pubmed.ncbi.nlm.nih.gov/39356739"},"language":"en","primary_location":{"id":"doi:10.7554/elife.73832","doi":"https://doi.org/10.7554/elife.73832","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.73832","pdf_url":"https://elifesciences.org/download/aHR0cHM6Ly9jZG4uZWxpZmVzY2llbmNlcy5vcmcvYXJ0aWNsZXMvNzM4MzIvZWxpZmUtNzM4MzItdjIucGRmP2Nhbm9uaWNhbFVyaT1odHRwczovL2VsaWZlc2NpZW5jZXMub3JnL2FydGljbGVzLzczODMy/elife-73832-v2.pdf?_hash=oJW%2FHX%2F8B%2Fus8cUbkS3RhyzWiC685FImZW7Xx2xmNRM%3D","source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"eLife","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://elifesciences.org/download/aHR0cHM6Ly9jZG4uZWxpZmVzY2llbmNlcy5vcmcvYXJ0aWNsZXMvNzM4MzIvZWxpZmUtNzM4MzItdjIucGRmP2Nhbm9uaWNhbFVyaT1odHRwczovL2VsaWZlc2NpZW5jZXMub3JnL2FydGljbGVzLzczODMy/elife-73832-v2.pdf?_hash=oJW%2FHX%2F8B%2Fus8cUbkS3RhyzWiC685FImZW7Xx2xmNRM%3D","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042207462","display_name":"Maruti Nandan Rai","orcid":"https://orcid.org/0000-0002-3430-9263","observed_orcids":["https://orcid.org/0000-0002-3430-9263"]},"institutions":[{"id":"https://openalex.org/I204512498","display_name":"University of Macau","ror":"https://ror.org/01r4q9n85","country_code":"MO","type":"education","lineage":["https://openalex.org/I204512498"]}],"countries":["MO"],"is_corresponding":false,"raw_author_name":"Maruti Nandan Rai","raw_affiliation_strings":["Faculty of Health Sciences, University of Macau"],"raw_orcid":"https://orcid.org/0000-0002-3430-9263","affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences, University of Macau","institution_ids":["https://openalex.org/I204512498"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Qing Lan","orcid":"https://orcid.org/0009-0008-3978-7281","observed_orcids":["https://orcid.org/0009-0008-3978-7281"]},"institutions":[{"id":"https://openalex.org/I204512498","display_name":"University of Macau","ror":"https://ror.org/01r4q9n85","country_code":"MO","type":"education","lineage":["https://openalex.org/I204512498"]}],"countries":["MO"],"is_corresponding":false,"raw_author_name":"Qing Lan","raw_affiliation_strings":["Faculty of Health Sciences, University of Macau"],"raw_orcid":"https://orcid.org/0009-0008-3978-7281","affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences, University of Macau","institution_ids":["https://openalex.org/I204512498"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040581077","display_name":"Chirag Parsania","orcid":"https://orcid.org/0000-0003-4873-2385","observed_orcids":["https://orcid.org/0000-0003-4873-2385"]},"institutions":[{"id":"https://openalex.org/I204512498","display_name":"University of Macau","ror":"https://ror.org/01r4q9n85","country_code":"MO","type":"education","lineage":["https://openalex.org/I204512498"]}],"countries":["MO"],"is_corresponding":false,"raw_author_name":"Chirag Parsania","raw_affiliation_strings":["Faculty of Health Sciences, University of Macau"],"raw_orcid":"https://orcid.org/0000-0003-4873-2385","affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences, University of Macau","institution_ids":["https://openalex.org/I204512498"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080874720","display_name":"Rikky Rai","orcid":"https://orcid.org/0000-0002-8786-5650","observed_orcids":["https://orcid.org/0000-0002-8786-5650"]},"institutions":[{"id":"https://openalex.org/I204512498","display_name":"University of Macau","ror":"https://ror.org/01r4q9n85","country_code":"MO","type":"education","lineage":["https://openalex.org/I204512498"]}],"countries":["MO"],"is_corresponding":false,"raw_author_name":"Rikky Rai","raw_affiliation_strings":["Faculty of Health Sciences, University of Macau"],"raw_orcid":"https://orcid.org/0000-0002-8786-5650","affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences, University of Macau","institution_ids":["https://openalex.org/I204512498"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090906050","display_name":"Niranjan Shirgaonkar","orcid":"https://orcid.org/0000-0001-6078-1409","observed_orcids":["https://orcid.org/0000-0001-6078-1409"]},"institutions":[{"id":"https://openalex.org/I204512498","display_name":"University of Macau","ror":"https://ror.org/01r4q9n85","country_code":"MO","type":"education","lineage":["https://openalex.org/I204512498"]}],"countries":["MO"],"is_corresponding":false,"raw_author_name":"Niranjan Shirgaonkar","raw_affiliation_strings":["Faculty of Health Sciences, University of Macau"],"raw_orcid":"https://orcid.org/0000-0001-6078-1409","affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences, University of Macau","institution_ids":["https://openalex.org/I204512498"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082582375","display_name":"Ruiwen Chen","orcid":"https://orcid.org/0000-0002-8714-0043","observed_orcids":["https://orcid.org/0000-0002-8714-0043","https://orcid.org/0000-0001-8780-1078","https://orcid.org/0000-0002-6735-8600","https://orcid.org/0009-0009-0272-9827"]},"institutions":[{"id":"https://openalex.org/I204512498","display_name":"University of Macau","ror":"https://ror.org/01r4q9n85","country_code":"MO","type":"education","lineage":["https://openalex.org/I204512498"]}],"countries":["MO"],"is_corresponding":false,"raw_author_name":"Ruiwen Chen","raw_affiliation_strings":["Faculty of Health Sciences, University of Macau"],"raw_orcid":"https://orcid.org/0000-0001-8780-1078","affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences, University of Macau","institution_ids":["https://openalex.org/I204512498"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100768717","display_name":"Li Shen","orcid":"https://orcid.org/0000-0002-0436-0199","observed_orcids":["https://orcid.org/0000-0002-0436-0199"]},"institutions":[{"id":"https://openalex.org/I204512498","display_name":"University of Macau","ror":"https://ror.org/01r4q9n85","country_code":"MO","type":"education","lineage":["https://openalex.org/I204512498"]}],"countries":["MO"],"is_corresponding":false,"raw_author_name":"Li Shen","raw_affiliation_strings":["Faculty of Health Sciences, University of Macau","Gene Expression, Genomics and Bioinformatics Core, Faculty of Health Sciences, University of Macau"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences, University of Macau","institution_ids":["https://openalex.org/I204512498"]},{"raw_affiliation_string":"Gene Expression, Genomics and Bioinformatics Core, Faculty of Health Sciences, University of Macau","institution_ids":["https://openalex.org/I204512498"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011030114","display_name":"Kaeling Tan","orcid":"https://orcid.org/0000-0002-3347-7628","observed_orcids":["https://orcid.org/0000-0002-3347-7628"]},"institutions":[{"id":"https://openalex.org/I204512498","display_name":"University of Macau","ror":"https://ror.org/01r4q9n85","country_code":"MO","type":"education","lineage":["https://openalex.org/I204512498"]}],"countries":["MO"],"is_corresponding":false,"raw_author_name":"Kaeling Tan","raw_affiliation_strings":["Faculty of Health Sciences, University of Macau","Gene Expression, Genomics and Bioinformatics Core, Faculty of Health Sciences, University of Macau"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences, University of Macau","institution_ids":["https://openalex.org/I204512498"]},{"raw_affiliation_string":"Gene Expression, Genomics and Bioinformatics Core, Faculty of Health Sciences, University of Macau","institution_ids":["https://openalex.org/I204512498"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023829717","display_name":"Koon Ho Wong","orcid":"https://orcid.org/0000-0002-9264-5118","observed_orcids":["https://orcid.org/0000-0002-9264-5118"]},"institutions":[{"id":"https://openalex.org/I204512498","display_name":"University of Macau","ror":"https://ror.org/01r4q9n85","country_code":"MO","type":"education","lineage":["https://openalex.org/I204512498"]}],"countries":["MO"],"is_corresponding":false,"raw_author_name":"Koon Ho Wong","raw_affiliation_strings":["Faculty of Health Sciences, University of Macau","Institute of Translational Medicine, Faculty of Health Sciences, University of Macau,Avenida da Universidade","MoE Frontiers Science Center for Precision Oncology, University of Macau"],"raw_orcid":"https://orcid.org/0000-0002-9264-5118","affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences, University of Macau","institution_ids":["https://openalex.org/I204512498"]},{"raw_affiliation_string":"Institute of Translational Medicine, Faculty of Health Sciences, University of Macau,Avenida da Universidade","institution_ids":["https://openalex.org/I204512498"]},{"raw_affiliation_string":"MoE Frontiers Science Center for Precision Oncology, University of Macau","institution_ids":["https://openalex.org/I204512498"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I204512498"],"apc_list":{"value":3000,"currency":"USD","value_usd":2500},"apc_paid":{"value":3000,"currency":"USD","value_usd":2500},"fwci":0.6965,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.6518728,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"13","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.7095000147819519,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.7095000147819519,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.2766000032424927,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11037","display_name":"Fungal Infections and Studies","score":0.004399999976158142,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/candida-glabrata","display_name":"Candida glabrata","score":1.0},{"id":"https://openalex.org/keywords/macrophage-infection","display_name":"macrophage infection","score":0.9470000267028809},{"id":"https://openalex.org/keywords/transcription-factors","display_name":"transcription factors","score":0.781000018119812},{"id":"https://openalex.org/keywords/fluconazole-resistance","display_name":"fluconazole resistance","score":0.8519999980926514},{"id":"https://openalex.org/keywords/host-pathogen-interaction","display_name":"host-pathogen interaction","score":0.875},{"id":"https://openalex.org/keywords/virulence","display_name":"virulence","score":0.7279999852180481},{"id":"https://openalex.org/keywords/rna-polymerase-ii-occupancy","display_name":"RNA polymerase II occupancy","score":0.824999988079071},{"id":"https://openalex.org/keywords/transcriptional-regulation","display_name":"transcriptional regulation","score":0.5809999704360962}],"concepts":[{"id":"https://openalex.org/C2780670043","wikidata":"https://www.wikidata.org/wiki/Q139137","display_name":"Candida glabrata","level":3,"score":0.8110495209693909},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7546622157096863},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.6104369163513184},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5767855048179626},{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.5587779879570007},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5197674632072449},{"id":"https://openalex.org/C2776460866","wikidata":"https://www.wikidata.org/wiki/Q170065","display_name":"Pathogen","level":2,"score":0.5115838646888733},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.5045424699783325},{"id":"https://openalex.org/C2781090273","wikidata":"https://www.wikidata.org/wiki/Q1623405","display_name":"Virulence factor","level":4,"score":0.4895835816860199},{"id":"https://openalex.org/C2780651595","wikidata":"https://www.wikidata.org/wiki/Q411478","display_name":"Fluconazole","level":3,"score":0.46238747239112854},{"id":"https://openalex.org/C114851261","wikidata":"https://www.wikidata.org/wiki/Q12147416","display_name":"Drug resistance","level":2,"score":0.447894424200058},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.42714723944664},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.3538326025009155},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.34355658292770386},{"id":"https://openalex.org/C2780917455","wikidata":"https://www.wikidata.org/wiki/Q310443","display_name":"Candida albicans","level":2,"score":0.1552431285381317},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.14547908306121826},{"id":"https://openalex.org/C2779548794","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal","level":2,"score":0.10778003931045532}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D002177","descriptor_name":"Candidiasis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002177","descriptor_name":"Candidiasis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002177","descriptor_name":"Candidiasis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002177","descriptor_name":"Candidiasis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002177","descriptor_name":"Candidiasis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002177","descriptor_name":"Candidiasis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002177","descriptor_name":"Candidiasis","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D002177","descriptor_name":"Candidiasis","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D002177","descriptor_name":"Candidiasis","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D002177","descriptor_name":"Candidiasis","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D002177","descriptor_name":"Candidiasis","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D002177","descriptor_name":"Candidiasis","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D012319","descriptor_name":"RNA Polymerase II","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012319","descriptor_name":"RNA Polymerase II","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012319","descriptor_name":"RNA Polymerase II","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012319","descriptor_name":"RNA Polymerase II","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012319","descriptor_name":"RNA Polymerase II","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012319","descriptor_name":"RNA Polymerase II","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012319","descriptor_name":"RNA Polymerase II","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012319","descriptor_name":"RNA Polymerase II","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012319","descriptor_name":"RNA Polymerase II","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012319","descriptor_name":"RNA Polymerase II","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012319","descriptor_name":"RNA Polymerase II","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012319","descriptor_name":"RNA Polymerase II","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014774","descriptor_name":"Virulence","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014774","descriptor_name":"Virulence","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014774","descriptor_name":"Virulence","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014774","descriptor_name":"Virulence","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014774","descriptor_name":"Virulence","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014774","descriptor_name":"Virulence","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015725","descriptor_name":"Fluconazole","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D015725","descriptor_name":"Fluconazole","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D015725","descriptor_name":"Fluconazole","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D015725","descriptor_name":"Fluconazole","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D015725","descriptor_name":"Fluconazole","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D015725","descriptor_name":"Fluconazole","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D015966","descriptor_name":"Gene Expression Regulation, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015966","descriptor_name":"Gene Expression Regulation, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015966","descriptor_name":"Gene Expression Regulation, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015966","descriptor_name":"Gene Expression Regulation, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015966","descriptor_name":"Gene Expression Regulation, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015966","descriptor_name":"Gene Expression Regulation, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D025141","descriptor_name":"Drug Resistance, Fungal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D025141","descriptor_name":"Drug Resistance, Fungal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D025141","descriptor_name":"Drug Resistance, Fungal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D025141","descriptor_name":"Drug Resistance, Fungal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D025141","descriptor_name":"Drug Resistance, Fungal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D025141","descriptor_name":"Drug Resistance, Fungal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D041221","descriptor_name":"Candida glabrata","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D041221","descriptor_name":"Candida glabrata","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D041221","descriptor_name":"Candida glabrata","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D041221","descriptor_name":"Candida glabrata","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D041221","descriptor_name":"Candida glabrata","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D041221","descriptor_name":"Candida glabrata","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D041221","descriptor_name":"Candida glabrata","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D041221","descriptor_name":"Candida glabrata","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D041221","descriptor_name":"Candida glabrata","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D041221","descriptor_name":"Candida glabrata","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D041221","descriptor_name":"Candida glabrata","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D041221","descriptor_name":"Candida glabrata","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.7554/elife.73832","doi":"https://doi.org/10.7554/elife.73832","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.73832","pdf_url":"https://elifesciences.org/download/aHR0cHM6Ly9jZG4uZWxpZmVzY2llbmNlcy5vcmcvYXJ0aWNsZXMvNzM4MzIvZWxpZmUtNzM4MzItdjIucGRmP2Nhbm9uaWNhbFVyaT1odHRwczovL2VsaWZlc2NpZW5jZXMub3JnL2FydGljbGVzLzczODMy/elife-73832-v2.pdf?_hash=oJW%2FHX%2F8B%2Fus8cUbkS3RhyzWiC685FImZW7Xx2xmNRM%3D","source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"eLife","raw_type":"journal-article"},{"id":"doi:10.1101/2021.09.28.462173","doi":"https://doi.org/10.1101/2021.09.28.462173","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2021.09.28.462173","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2021/09/28/2021.09.28.462173.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmid:39356739","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39356739","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"eLife","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11554308","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11554308","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11554308/pdf/elife-73832.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"eLife","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:b7ebf0bd81384d808471dd22194115b9","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/b7ebf0bd81384d808471dd22194115b9","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"eLife, Vol 13 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.7554/elife.73832","doi":"https://doi.org/10.7554/elife.73832","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.73832","pdf_url":"https://elifesciences.org/download/aHR0cHM6Ly9jZG4uZWxpZmVzY2llbmNlcy5vcmcvYXJ0aWNsZXMvNzM4MzIvZWxpZmUtNzM4MzItdjIucGRmP2Nhbm9uaWNhbFVyaT1odHRwczovL2VsaWZlc2NpZW5jZXMub3JnL2FydGljbGVzLzczODMy/elife-73832-v2.pdf?_hash=oJW%2FHX%2F8B%2Fus8cUbkS3RhyzWiC685FImZW7Xx2xmNRM%3D","source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"eLife","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.8199999928474426,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1352437481","display_name":null,"funder_award_id":"MYRG201900099-FHS","funder_id":"https://openalex.org/F4320336459","funder_display_name":"Research Services and Knowledge Transfer Office, University of Macau"},{"id":"https://openalex.org/G2110635143","display_name":null,"funder_award_id":"MYRG2019","funder_id":"https://openalex.org/F4320322841","funder_display_name":"Universidade de Macau"},{"id":"https://openalex.org/G2677469158","display_name":null,"funder_award_id":"MYRG2019-00099-FHS","funder_id":"https://openalex.org/F4320322841","funder_display_name":"Universidade de Macau"},{"id":"https://openalex.org/G3043060419","display_name":null,"funder_award_id":"MYRG2022-00107-FHS","funder_id":"https://openalex.org/F4320336459","funder_display_name":"Research Services and Knowledge Transfer Office, University of Macau"},{"id":"https://openalex.org/G3746443632","display_name":null,"funder_award_id":"0033/2021/A1","funder_id":"https://openalex.org/F4320323893","funder_display_name":"Fundo para o Desenvolvimento das Ci\u00eancias e da Tecnologia"},{"id":"https://openalex.org/G5055162524","display_name":null,"funder_award_id":"C5012-15E","funder_id":"https://openalex.org/F4320329815","funder_display_name":"Hong Kong Government"},{"id":"https://openalex.org/G8022726380","display_name":null,"funder_award_id":"MYRG2022-00107-FHS","funder_id":"https://openalex.org/F4320322841","funder_display_name":"Universidade de Macau"},{"id":"https://openalex.org/G8330575380","display_name":null,"funder_award_id":"0099/2022/A2","funder_id":"https://openalex.org/F4320323893","funder_display_name":"Fundo para o Desenvolvimento das Ci\u00eancias e da Tecnologia"}],"funders":[{"id":"https://openalex.org/F4320322841","display_name":"Universidade de Macau","ror":"https://ror.org/01r4q9n85"},{"id":"https://openalex.org/F4320323893","display_name":"Fundo para o Desenvolvimento das Ci\u00eancias e da Tecnologia","ror":"https://ror.org/05vna4324"},{"id":"https://openalex.org/F4320329815","display_name":"Hong Kong Government","ror":"https://ror.org/034179816"},{"id":"https://openalex.org/F4320336459","display_name":"Research Services and Knowledge Transfer Office, University of Macau","ror":null},{"id":"https://openalex.org/F4320337292","display_name":"Faculdade de Ci\u00eancias da Sa\u00fade, Universidade de Macau","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4403051637.pdf","grobid_xml":"https://content.openalex.org/works/W4403051637.grobid-xml"},"referenced_works_count":73,"referenced_works":["https://openalex.org/W1570863047","https://openalex.org/W1647692986","https://openalex.org/W1932435612","https://openalex.org/W1950399079","https://openalex.org/W1953102621","https://openalex.org/W1981261463","https://openalex.org/W1982281067","https://openalex.org/W1983222530","https://openalex.org/W1986207589","https://openalex.org/W2005629359","https://openalex.org/W2020653359","https://openalex.org/W2022006512","https://openalex.org/W2031668747","https://openalex.org/W2035155416","https://openalex.org/W2052375196","https://openalex.org/W2054716142","https://openalex.org/W2063183241","https://openalex.org/W2066001875","https://openalex.org/W2068373367","https://openalex.org/W2070667133","https://openalex.org/W2080433494","https://openalex.org/W2085509368","https://openalex.org/W2086808847","https://openalex.org/W2093146349","https://openalex.org/W2100246797","https://openalex.org/W2110874942","https://openalex.org/W2116161166","https://openalex.org/W2117131162","https://openalex.org/W2120783296","https://openalex.org/W2124863746","https://openalex.org/W2129785061","https://openalex.org/W2135228917","https://openalex.org/W2138207763","https://openalex.org/W2141260639","https://openalex.org/W2141327598","https://openalex.org/W2146808643","https://openalex.org/W2152193146","https://openalex.org/W2155494286","https://openalex.org/W2157009395","https://openalex.org/W2161971164","https://openalex.org/W2164379560","https://openalex.org/W2166909888","https://openalex.org/W2167191781","https://openalex.org/W2167867974","https://openalex.org/W2170551349","https://openalex.org/W2171808845","https://openalex.org/W2179438025","https://openalex.org/W2236699923","https://openalex.org/W2261682386","https://openalex.org/W2338841684","https://openalex.org/W2345837905","https://openalex.org/W2520825309","https://openalex.org/W2525765531","https://openalex.org/W2530772399","https://openalex.org/W2565480917","https://openalex.org/W2589036275","https://openalex.org/W2592604332","https://openalex.org/W2741597852","https://openalex.org/W2767031614","https://openalex.org/W2782394839","https://openalex.org/W2800526695","https://openalex.org/W2908923775","https://openalex.org/W2909945878","https://openalex.org/W2964849163","https://openalex.org/W2978955949","https://openalex.org/W2987076581","https://openalex.org/W3019645196","https://openalex.org/W3092283310","https://openalex.org/W4310601934","https://openalex.org/W4321373243","https://openalex.org/W4387141694","https://openalex.org/W4388522045","https://openalex.org/W4399321742"],"related_works":["https://openalex.org/W2005467096","https://openalex.org/W2242798809","https://openalex.org/W2081022186","https://openalex.org/W2097078456","https://openalex.org/W2735171233","https://openalex.org/W1583826780","https://openalex.org/W1969010760","https://openalex.org/W2900808791","https://openalex.org/W2900583711","https://openalex.org/W2163386885"],"abstract_inverted_index":{"Abstract":[0],"Candida":[1],"glabrata":[2,28,57,75,162],"can":[3],"thrive":[4],"inside":[5,30],"macrophages":[6,31,166],"and":[7,32,107,153,167],"tolerate":[8],"high":[9,67],"levels":[10],"of":[11,38,81,89,111],"azole":[12,140],"antifungals.":[13],"These":[14],"innate":[15],"abilities":[16],"render":[17],"infections":[18],"by":[19],"this":[20,143],"human":[21],"pathogen":[22],"a":[23,146,155],"clinical":[24],"challenge.":[25],"How":[26],"C.":[27,56,74,161],"reacts":[29],"what":[33],"is":[34],"the":[35,100],"molecular":[36],"basis":[37],"its":[39,60,117],"drug":[40,130,168],"tolerance":[41],"are":[42],"not":[43,121],"well":[44],"understood.":[45],"Here,":[46],"we":[47,133],"mapped":[48],"genome-wide":[49],"RNA":[50],"polymerase":[51],"II":[52],"(RNAPII)":[53],"occupancy":[54],"in":[55,66,105,165],"to":[58,77],"delineate":[59],"transcriptional":[61],"responses":[62,76],"during":[63],"macrophage":[64,78,102],"infection":[65],"temporal":[68],"resolution.":[69],"RNAPII":[70],"profiles":[71],"revealed":[72,116],"dynamic":[73],"with":[79,129],"genes":[80,124,127],"specialized":[82],"pathways":[83],"activated":[84],"chronologically":[85],"at":[86],"different":[87],"times":[88],"infection.":[90],"We":[91],"identified":[92],"an":[93],"uncharacterized":[94],"transcription":[95,157],"factor":[96,158],"(CgXbp1)":[97],"important":[98,159],"for":[99,149,160],"chronological":[101],"response,":[103],"survival":[104,164],"macrophages,":[106],"virulence.":[108],"Genome-wide":[109],"mapping":[110],"CgXbp1":[112,136],"direct":[113],"targets":[114],"further":[115],"multi-faceted":[118],"functions,":[119],"regulating":[120],"only":[122],"virulence-related":[123],"but":[125],"also":[126,138],"associated":[128],"resistance.":[131,141],"Finally,":[132],"showed":[134],"that":[135],"indeed":[137],"affects":[139],"Overall,":[142],"work":[144],"presents":[145],"powerful":[147],"approach":[148],"examining":[150],"host-pathogen":[151],"interaction":[152],"uncovers":[154],"novel":[156],"\u2019s":[163],"tolerance.":[169]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2024-10-02T00:00:00"}