{"id":"https://openalex.org/W4402945504","doi":"https://doi.org/10.1016/j.ijrobp.2024.07.786","title":"Enrichment of Tumor-Associated Fragmentomic Features in Plasma with Focused Ultrasound-Enabled Liquid Biopsy in Glioma Patients","display_name":"Enrichment of Tumor-Associated Fragmentomic Features in Plasma with Focused Ultrasound-Enabled Liquid Biopsy in Glioma Patients","publication_year":2024,"publication_date":"2024-09-27","ids":{"openalex":"https://openalex.org/W4402945504","doi":"https://doi.org/10.1016/j.ijrobp.2024.07.786"},"language":"en","primary_location":{"id":"doi:10.1016/j.ijrobp.2024.07.786","doi":"https://doi.org/10.1016/j.ijrobp.2024.07.786","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1016/j.ijrobp.2024.07.786","pdf_url":"https://www.redjournal.org/article/S0360-3016(24)01548-7/pdf","source":{"id":"https://openalex.org/S110533041","display_name":"International Journal of Radiation Oncology*Biology*Physics","issn_l":"0360-3016","issn":["0360-3016","1879-355X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Radiation Oncology*Biology*Physics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.redjournal.org/article/S0360-3016(24)01548-7/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087963216","display_name":"Pradeep S. Chauhan","orcid":"https://orcid.org/0000-0003-4304-011X","observed_orcids":["https://orcid.org/0000-0003-4304-011X"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P.S. Chauhan","raw_affiliation_strings":["Department of Radiation Oncology, Mayo Clinic, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010073399","display_name":"Irfan Alahi","orcid":"https://orcid.org/0009-0008-4577-3548","observed_orcids":["https://orcid.org/0009-0008-4577-3548"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"I. Alahi","raw_affiliation_strings":["Department of Radiation Oncology, Mayo Clinic, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102011950","display_name":"Yuan Ji","orcid":"https://orcid.org/0000-0002-2631-9082","observed_orcids":["https://orcid.org/0000-0002-2631-9082"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Yuan","raw_affiliation_strings":["Washington University School of Medicine, St Louis, MO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Washington University School of Medicine, St Louis, MO","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":null,"display_name":"L. Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. Xu","raw_affiliation_strings":["Washington University School of Medicine, St Louis, MO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Washington University School of Medicine, St Louis, MO","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023493854","display_name":"Peter K. W. Harris","orcid":"https://orcid.org/0000-0003-1557-1722","observed_orcids":["https://orcid.org/0000-0003-1557-1722"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P.K. Harris","raw_affiliation_strings":["Washington University School of Medicine, St. Louis, MO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Washington University School of Medicine, St. Louis, MO","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076290243","display_name":"Chih\u2010Yen Chien","orcid":"https://orcid.org/0000-0002-6690-6038","observed_orcids":["https://orcid.org/0000-0002-6690-6038"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C.Y. Chien","raw_affiliation_strings":["Washington University School of Medicine, St Louis, MO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Washington University School of Medicine, St Louis, MO","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079578194","display_name":"Siaka Fadera","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Fadera","raw_affiliation_strings":["Washington University School of Medicine, St Louis, MO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Washington University School of Medicine, St Louis, MO","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059475970","display_name":"Andrew L. Stark","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Stark","raw_affiliation_strings":["Washington University School of Medicine, St Louis, MO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Washington University School of Medicine, St Louis, MO","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031146709","display_name":"Hong Chen","orcid":"https://orcid.org/0000-0003-1904-0857","observed_orcids":["https://orcid.org/0000-0003-1904-0857"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. Chen","raw_affiliation_strings":["Washington University School of Medicine, St Louis, MO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Washington University School of Medicine, St Louis, MO","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077868821","display_name":"Eric C. Leuthardt","orcid":"https://orcid.org/0000-0003-4154-3135","observed_orcids":["https://orcid.org/0000-0003-4154-3135"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E.C. Leuthardt","raw_affiliation_strings":["Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070207276","display_name":"Aadel A. Chaudhuri","orcid":"https://orcid.org/0000-0003-3115-3061","observed_orcids":["https://orcid.org/0000-0003-3115-3061"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A.A. Chaudhuri","raw_affiliation_strings":["Department of Radiation Oncology, Mayo Clinic, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Mayo Clinic, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3940,"currency":"USD","value_usd":3940},"apc_paid":null,"fwci":0.6036,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.64325579,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"120","issue":"2","first_page":"e356","last_page":"e356"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.6273999810218811,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.6273999810218811,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.2605000138282776,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10958","display_name":"Ultrasound and Hyperthermia Applications","score":0.03920000046491623,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/focused-ultrasound","display_name":"focused ultrasound","score":0.9800000190734863},{"id":"https://openalex.org/keywords/glioma","display_name":"glioma","score":0.8370000123977661},{"id":"https://openalex.org/keywords/glioblastoma","display_name":"glioblastoma","score":0.9610000252723694},{"id":"https://openalex.org/keywords/liquid-biopsy","display_name":"liquid biopsy","score":0.8539999723434448},{"id":"https://openalex.org/keywords/blood-brain-barrier-disruption","display_name":"blood-brain barrier disruption","score":0.8529999852180481},{"id":"https://openalex.org/keywords/cell-free-dna","display_name":"cell-free DNA","score":0.7319999933242798},{"id":"https://openalex.org/keywords/tumor-fraction-estimation","display_name":"tumor fraction estimation","score":0.7730000019073486},{"id":"https://openalex.org/keywords/copy-number-alterations","display_name":"copy number alterations","score":0.656000018119812},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.5699999928474426},{"id":"https://openalex.org/keywords/plasma-biomarkers","display_name":"plasma biomarkers","score":0.5249999761581421},{"id":"https://openalex.org/keywords/non-invasive-cancer-detection","display_name":"non-invasive cancer detection","score":0.5479999780654907},{"id":"https://openalex.org/keywords/low-grade-glioma","display_name":"low-grade glioma","score":0.5830000042915344},{"id":"https://openalex.org/keywords/neuronavigation","display_name":"neuronavigation","score":0.3869999945163727},{"id":"https://openalex.org/keywords/ichorcna","display_name":"ichorCNA","score":0.6140000224113464}],"concepts":[{"id":"https://openalex.org/C2778227246","wikidata":"https://www.wikidata.org/wiki/Q1365309","display_name":"Glioma","level":2,"score":0.775765597820282},{"id":"https://openalex.org/C2779529041","wikidata":"https://www.wikidata.org/wiki/Q22349364","display_name":"Liquid biopsy","level":3,"score":0.7472144365310669},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.5668506622314453},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.5427508354187012},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4001973271369934},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3681170642375946},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3567269444465637},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.28926581144332886},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.20501691102981567},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.10510122776031494}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.ijrobp.2024.07.786","doi":"https://doi.org/10.1016/j.ijrobp.2024.07.786","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1016/j.ijrobp.2024.07.786","pdf_url":"https://www.redjournal.org/article/S0360-3016(24)01548-7/pdf","source":{"id":"https://openalex.org/S110533041","display_name":"International Journal of Radiation Oncology*Biology*Physics","issn_l":"0360-3016","issn":["0360-3016","1879-355X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Radiation Oncology*Biology*Physics","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.ijrobp.2024.07.786","doi":"https://doi.org/10.1016/j.ijrobp.2024.07.786","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1016/j.ijrobp.2024.07.786","pdf_url":"https://www.redjournal.org/article/S0360-3016(24)01548-7/pdf","source":{"id":"https://openalex.org/S110533041","display_name":"International Journal of Radiation Oncology*Biology*Physics","issn_l":"0360-3016","issn":["0360-3016","1879-355X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Radiation Oncology*Biology*Physics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4402945504.pdf","grobid_xml":"https://content.openalex.org/works/W4402945504.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4388589450","https://openalex.org/W4386799303","https://openalex.org/W3216141632","https://openalex.org/W3212618582","https://openalex.org/W4416141501","https://openalex.org/W4410820588","https://openalex.org/W7204213091","https://openalex.org/W7213236442","https://openalex.org/W7169008686","https://openalex.org/W4400288033"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2}],"updated_date":"2026-10-26T11:51:55.731654","created_date":"2024-09-29T00:00:00"}