{"id":"https://openalex.org/W4402879606","doi":"https://doi.org/10.1039/d0cb00033g/v2/response1","title":"Author response for \"Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors\"","display_name":"Author response for \"Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors\"","publication_year":2020,"publication_date":"2020-07-28","ids":{"openalex":"https://openalex.org/W4402879606","doi":"https://doi.org/10.1039/d0cb00033g/v2/response1"},"language":"en","primary_location":{"id":"doi:10.1039/d0cb00033g/v2/response1","doi":"https://doi.org/10.1039/d0cb00033g/v2/response1","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1039/d0cb00033g/v2/response1","pdf_url":null,"source":{"id":"https://openalex.org/S4363604615","display_name":"Publons reviews and discussion","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"peer-review"},"volume":null,"type":"peer-review","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Seixas, Joao D.","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Seixas, Joao D.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101921832","display_name":"B\u00e1rbara B. Sousa","orcid":"https://orcid.org/0000-0002-2567-1826","observed_orcids":["https://orcid.org/0000-0002-2567-1826"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sousa, Barbara B.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042517924","display_name":"Marta C. Marques","orcid":"https://orcid.org/0000-0002-5093-5918","observed_orcids":["https://orcid.org/0000-0002-5093-5918"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marques, Marta C.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010901342","display_name":"Ana Guerreiro","orcid":"https://orcid.org/0000-0002-2173-6514","observed_orcids":["https://orcid.org/0000-0002-2173-6514"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Guerreiro, Ana","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025135123","display_name":"Rui Traquete","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Traquete, Rui","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082017604","display_name":"Tiago Rodrigues","orcid":"https://orcid.org/0000-0002-1581-5654","observed_orcids":["https://orcid.org/0000-0002-1581-5654","https://orcid.org/0000-0002-1255-9667"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rodrigues, Tiago","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029566297","display_name":"In\u00eas S. Albuquerque","orcid":"https://orcid.org/0000-0002-1108-0961","observed_orcids":["https://orcid.org/0000-0002-1108-0961"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Albuquerque, Ines S.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054830737","display_name":"Marcos F. Q. Sousa","orcid":"https://orcid.org/0000-0003-3766-3900","observed_orcids":["https://orcid.org/0000-0003-3766-3900"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sousa, Marcos F. Q.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021898564","display_name":"Ana Rita Lemos","orcid":"https://orcid.org/0000-0002-3987-4771","observed_orcids":["https://orcid.org/0000-0002-3987-4771"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lemos, Ana R.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016343135","display_name":"Pedro M. F. Sousa","orcid":"https://orcid.org/0000-0002-6672-3610","observed_orcids":["https://orcid.org/0000-0002-6672-3610"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sousa, Pedro M. F.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060788704","display_name":"Tiago M. Bandeiras","orcid":"https://orcid.org/0000-0001-6089-6089","observed_orcids":["https://orcid.org/0000-0001-6089-6089"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bandeiras, Tiago M.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042348341","display_name":"Di Wu","orcid":"https://orcid.org/0000-0001-9748-4408","observed_orcids":["https://orcid.org/0000-0001-9748-4408"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wu, Di","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085006661","display_name":"Shelby K. Doyle","orcid":"https://orcid.org/0000-0003-0889-6959","observed_orcids":["https://orcid.org/0000-0003-0889-6959"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Doyle, Shelby K.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003402066","display_name":"Carol V. Robinson","orcid":"https://orcid.org/0000-0001-7829-5505","observed_orcids":["https://orcid.org/0000-0001-7829-5505"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robinson, Carol V.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025449695","display_name":"Angela N. Koehler","orcid":"https://orcid.org/0000-0001-6980-5534","observed_orcids":["https://orcid.org/0000-0001-6980-5534"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Koehler, Angela N.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078435865","display_name":"Francisco Corzana","orcid":"https://orcid.org/0000-0001-5597-8127","observed_orcids":["https://orcid.org/0000-0001-5597-8127"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Corzana, Francisco","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063144012","display_name":"Pedro M. Matias","orcid":"https://orcid.org/0000-0001-6170-451X","observed_orcids":["https://orcid.org/0000-0001-6170-451X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Matias, Pedro M.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5050238909","display_name":"Gon\u00e7alo J. L. Bernardes","orcid":"https://orcid.org/0000-0001-6594-8917","observed_orcids":["https://orcid.org/0000-0001-6594-8917"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bernardes, Goncalo J. L.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.21719999611377716,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.21719999611377716,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.11249999701976776,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12534","display_name":"Protein Degradation and Inhibitors","score":0.06949999928474426,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/covalent-attachment","display_name":"covalent binding","score":0.7419999837875366},{"id":"https://openalex.org/keywords/rational-drug-design","display_name":"rational drug design","score":0.8019999861717224},{"id":"https://openalex.org/keywords/kinase-inhibitors","display_name":"kinase inhibitors","score":0.5910000205039978},{"id":"https://openalex.org/keywords/protein-ligand-binding-mechanism","display_name":"protein-ligand binding mechanism","score":0.6240000128746033},{"id":"https://openalex.org/keywords/structure-activity-relationship","display_name":"structure-activity relationship","score":0.5289999842643738}],"concepts":[{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5491651296615601},{"id":"https://openalex.org/C180577832","wikidata":"https://www.wikidata.org/wiki/Q127920","display_name":"Covalent bond","level":2,"score":0.4758184552192688},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4441795349121094},{"id":"https://openalex.org/C48677424","wikidata":"https://www.wikidata.org/wiki/Q6888088","display_name":"Mode (computer interface)","level":2,"score":0.41929471492767334},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.32703202962875366},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.28345105051994324},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.27088838815689087},{"id":"https://openalex.org/C107457646","wikidata":"https://www.wikidata.org/wiki/Q207434","display_name":"Human\u2013computer interaction","level":1,"score":0.07455092668533325},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1039/d0cb00033g/v2/response1","doi":"https://doi.org/10.1039/d0cb00033g/v2/response1","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1039/d0cb00033g/v2/response1","pdf_url":null,"source":{"id":"https://openalex.org/S4363604615","display_name":"Publons reviews and discussion","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"peer-review"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3082052009","https://openalex.org/W4236496828","https://openalex.org/W7157592342","https://openalex.org/W7052478581","https://openalex.org/W3093091145","https://openalex.org/W7214616546","https://openalex.org/W2042846235","https://openalex.org/W3113224589","https://openalex.org/W2107086756","https://openalex.org/W7027425872"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2024-09-27T00:00:00"}