{"id":"https://openalex.org/W4402565124","doi":"https://doi.org/10.1063/5.0201465","title":"Poly(lactic-co-glycolic acid) nanoparticle fabrication, functionalization, and biological considerations for drug delivery","display_name":"Poly(lactic-co-glycolic acid) nanoparticle fabrication, functionalization, and biological considerations for drug delivery","publication_year":2024,"publication_date":"2024-09-01","ids":{"openalex":"https://openalex.org/W4402565124","doi":"https://doi.org/10.1063/5.0201465","pmid":"https://pubmed.ncbi.nlm.nih.gov/39296325","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11410388"},"language":"en","primary_location":{"id":"doi:10.1063/5.0201465","doi":"https://doi.org/10.1063/5.0201465","is_oa":true,"landing_page_url":"https://doi.org/10.1063/5.0201465","pdf_url":null,"source":{"id":"https://openalex.org/S173107507","display_name":"Biomicrofluidics","issn_l":"1932-1058","issn":["1932-1058"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320257","host_organization_name":"American Institute of Physics","host_organization_lineage":["https://openalex.org/P4310320257"],"host_organization_lineage_names":["American Institute of Physics"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomicrofluidics","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1063/5.0201465","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091014851","display_name":"Eric K. Marecki","orcid":"https://orcid.org/0009-0007-3640-2537","observed_orcids":["https://orcid.org/0009-0007-3640-2537"]},"institutions":[{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric K. Marecki","raw_affiliation_strings":["Department of Biomedical Engineering, The State University of New York at Buffalo 1 , Buffalo, New York 14260, USA","SMALL (Sensors and MicroActuators Learning Lab), Department of Electrical Engineering, The State University of New York at Buffalo 2 , Buffalo, New York 14260, USA"],"raw_orcid":"https://orcid.org/0009-0007-3640-2537","affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, The State University of New York at Buffalo 1 , Buffalo, New York 14260, USA","institution_ids":["https://openalex.org/I63190737"]},{"raw_affiliation_string":"SMALL (Sensors and MicroActuators Learning Lab), Department of Electrical Engineering, The State University of New York at Buffalo 2 , Buffalo, New York 14260, USA","institution_ids":["https://openalex.org/I63190737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079305440","display_name":"Kwang Wook Oh","orcid":"https://orcid.org/0000-0003-0078-6683","observed_orcids":["https://orcid.org/0000-0003-0078-6683"]},"institutions":[{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kwang W. Oh","raw_affiliation_strings":["Department of Biomedical Engineering, The State University of New York at Buffalo 1 , Buffalo, New York 14260, USA","SMALL (Sensors and MicroActuators Learning Lab), Department of Electrical Engineering, The State University of New York at Buffalo 2 , Buffalo, New York 14260, USA"],"raw_orcid":"https://orcid.org/0000-0003-0078-6683","affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, The State University of New York at Buffalo 1 , Buffalo, New York 14260, USA","institution_ids":["https://openalex.org/I63190737"]},{"raw_affiliation_string":"SMALL (Sensors and MicroActuators Learning Lab), Department of Electrical Engineering, The State University of New York at Buffalo 2 , Buffalo, New York 14260, USA","institution_ids":["https://openalex.org/I63190737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089211664","display_name":"Paul R. Knight","orcid":"https://orcid.org/0000-0002-9201-3305","observed_orcids":["https://orcid.org/0000-0002-9201-3305"]},"institutions":[{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul R. Knight","raw_affiliation_strings":["Department of Anesthesiology, The State University of New York at Buffalo 3 , Buffalo, New York 14203, USA"],"raw_orcid":"https://orcid.org/0000-0002-9201-3305","affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, The State University of New York at Buffalo 3 , Buffalo, New York 14203, USA","institution_ids":["https://openalex.org/I63190737"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044926801","display_name":"Bruce A. Davidson","orcid":"https://orcid.org/0000-0001-8223-1870","observed_orcids":["https://orcid.org/0000-0001-8223-1870"]},"institutions":[{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Bruce A. Davidson","raw_affiliation_strings":["Department of Anesthesiology, The State University of New York at Buffalo 3 , Buffalo, New York 14203, USA"],"raw_orcid":"https://orcid.org/0000-0001-8223-1870","affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, The State University of New York at Buffalo 3 , Buffalo, New York 14203, USA","institution_ids":["https://openalex.org/I63190737"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5044926801"],"corresponding_institution_ids":["https://openalex.org/I63190737"],"apc_list":null,"apc_paid":null,"fwci":0.3385,"has_fulltext":true,"cited_by_count":12,"citation_normalized_percentile":{"value":0.29046455,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"18","issue":"5","first_page":"051503","last_page":"051503"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11686","display_name":"Dendrimers and Hyperbranched Polymers","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2507","display_name":"Polymers and Plastics"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/poly-lactic-co-glycolic-acid","display_name":"poly(lactic-co-glycolic acid)","score":0.9490000009536743},{"id":"https://openalex.org/keywords/plga-nanoparticles","display_name":"PLGA nanoparticles","score":1.0},{"id":"https://openalex.org/keywords/nanoparticle-synthesis","display_name":"nanoparticle synthesis","score":0.9110000133514404},{"id":"https://openalex.org/keywords/nanoparticle-functionalization","display_name":"nanoparticle functionalization","score":0.9480000138282776},{"id":"https://openalex.org/keywords/drug-delivery","display_name":"drug delivery","score":0.8230000138282776},{"id":"https://openalex.org/keywords/encapsulation-efficiency","display_name":"encapsulation efficiency","score":0.9039999842643738},{"id":"https://openalex.org/keywords/nanoparticle-aggregation","display_name":"nanoparticle aggregation","score":0.7480000257492065},{"id":"https://openalex.org/keywords/surface-functionalization","display_name":"surface functionalization","score":0.5410000085830688},{"id":"https://openalex.org/keywords/targeted-drug-delivery","display_name":"targeted drug delivery","score":0.7570000290870667},{"id":"https://openalex.org/keywords/cellular-uptake","display_name":"cellular uptake","score":0.9850000143051147},{"id":"https://openalex.org/keywords/drug-release","display_name":"drug release","score":0.6639999747276306},{"id":"https://openalex.org/keywords/biodegradation","display_name":"biodegradation","score":0.8519999980926514},{"id":"https://openalex.org/keywords/nanoparticle-toxicity","display_name":"nanoparticle toxicity","score":0.8610000014305115}],"concepts":[{"id":"https://openalex.org/C2780472526","wikidata":"https://www.wikidata.org/wiki/Q409373","display_name":"Glycolic acid","level":4,"score":0.8271380662918091},{"id":"https://openalex.org/C2780165375","wikidata":"https://www.wikidata.org/wiki/Q2102907","display_name":"PLGA","level":3,"score":0.8210095167160034},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.7913997173309326},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.7212070226669312},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.6667582988739014},{"id":"https://openalex.org/C115537861","wikidata":"https://www.wikidata.org/wiki/Q7645993","display_name":"Surface modification","level":2,"score":0.6580637097358704},{"id":"https://openalex.org/C136525101","wikidata":"https://www.wikidata.org/wiki/Q5428139","display_name":"Fabrication","level":3,"score":0.5569797158241272},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.5026006698608398},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4980013370513916},{"id":"https://openalex.org/C126511603","wikidata":"https://www.wikidata.org/wiki/Q1261145","display_name":"Targeted drug delivery","level":3,"score":0.44556888937950134},{"id":"https://openalex.org/C2775920511","wikidata":"https://www.wikidata.org/wiki/Q161249","display_name":"Lactic acid","level":3,"score":0.4443855881690979},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.31851497292518616},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.16917815804481506},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0836927592754364},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1063/5.0201465","doi":"https://doi.org/10.1063/5.0201465","is_oa":true,"landing_page_url":"https://doi.org/10.1063/5.0201465","pdf_url":null,"source":{"id":"https://openalex.org/S173107507","display_name":"Biomicrofluidics","issn_l":"1932-1058","issn":["1932-1058"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320257","host_organization_name":"American Institute of Physics","host_organization_lineage":["https://openalex.org/P4310320257"],"host_organization_lineage_names":["American Institute of Physics"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomicrofluidics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11410388","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11410388","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11410388/pdf/BIOMGB-000018-051503_1.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomicrofluidics","raw_type":"Text"},{"id":"pmid:39296325","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39296325","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomicrofluidics","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1063/5.0201465","doi":"https://doi.org/10.1063/5.0201465","is_oa":true,"landing_page_url":"https://doi.org/10.1063/5.0201465","pdf_url":null,"source":{"id":"https://openalex.org/S173107507","display_name":"Biomicrofluidics","issn_l":"1932-1058","issn":["1932-1058"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320257","host_organization_name":"American Institute of Physics","host_organization_lineage":["https://openalex.org/P4310320257"],"host_organization_lineage_names":["American Institute of Physics"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomicrofluidics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.4300000071525574,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1867362502","display_name":"Immunotherapy for acute lung injury secondary to influenza","funder_award_id":"R01HL151498","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7936518430","display_name":"An adjuvanted influenza vaccine platform for dose sparing, multiplexing, and rapid deployment","funder_award_id":"1r41ai149954-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8751383122","display_name":null,"funder_award_id":"R41 AI149954","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":185,"referenced_works":["https://openalex.org/W88596619","https://openalex.org/W1498773598","https://openalex.org/W1512256229","https://openalex.org/W1772869976","https://openalex.org/W1817805606","https://openalex.org/W1843302206","https://openalex.org/W1963776452","https://openalex.org/W1964270561","https://openalex.org/W1966414861","https://openalex.org/W1967083835","https://openalex.org/W1973356985","https://openalex.org/W1975399536","https://openalex.org/W1985006200","https://openalex.org/W1987259801","https://openalex.org/W1988297189","https://openalex.org/W1992388165","https://openalex.org/W1993390114","https://openalex.org/W1993553803","https://openalex.org/W1995237117","https://openalex.org/W1995808140","https://openalex.org/W1996139192","https://openalex.org/W1996149727","https://openalex.org/W1997274211","https://openalex.org/W1998048783","https://openalex.org/W1998284209","https://openalex.org/W2001603955","https://openalex.org/W2002459172","https://openalex.org/W2004445422","https://openalex.org/W2005239277","https://openalex.org/W2005628086","https://openalex.org/W2009906157","https://openalex.org/W2013081613","https://openalex.org/W2014670154","https://openalex.org/W2015663833","https://openalex.org/W2015869127","https://openalex.org/W2018849246","https://openalex.org/W2019042150","https://openalex.org/W2020398834","https://openalex.org/W2021622952","https://openalex.org/W2023731083","https://openalex.org/W2025343509","https://openalex.org/W2025665604","https://openalex.org/W2027563992","https://openalex.org/W2027876233","https://openalex.org/W2029397995","https://openalex.org/W2035697316","https://openalex.org/W2035901751","https://openalex.org/W2037402194","https://openalex.org/W2038465668","https://openalex.org/W2045422540","https://openalex.org/W2051305606","https://openalex.org/W2055188415","https://openalex.org/W2058065015","https://openalex.org/W2060092406","https://openalex.org/W2060140728","https://openalex.org/W2060299421","https://openalex.org/W2060589763","https://openalex.org/W2061643831","https://openalex.org/W2061655961","https://openalex.org/W2066067415","https://openalex.org/W2066076859","https://openalex.org/W2066285818","https://openalex.org/W2066651265","https://openalex.org/W2066805764","https://openalex.org/W2069649187","https://openalex.org/W2070803838","https://openalex.org/W2071856768","https://openalex.org/W2078816106","https://openalex.org/W2080652468","https://openalex.org/W2083202100","https://openalex.org/W2083710155","https://openalex.org/W2085106089","https://openalex.org/W2086719948","https://openalex.org/W2087812848","https://openalex.org/W2088081239","https://openalex.org/W2088261391","https://openalex.org/W2094236242","https://openalex.org/W2095128842","https://openalex.org/W2095347946","https://openalex.org/W2096410549","https://openalex.org/W2100809064","https://openalex.org/W2105398112","https://openalex.org/W2107910518","https://openalex.org/W2108615682","https://openalex.org/W2115993724","https://openalex.org/W2115994196","https://openalex.org/W2116183504","https://openalex.org/W2117630026","https://openalex.org/W2134626448","https://openalex.org/W2135894523","https://openalex.org/W2138968683","https://openalex.org/W2143463421","https://openalex.org/W2155042744","https://openalex.org/W2157963288","https://openalex.org/W2164285516","https://openalex.org/W2164841185","https://openalex.org/W2165244515","https://openalex.org/W2166255592","https://openalex.org/W2170145492","https://openalex.org/W2171083652","https://openalex.org/W2174949225","https://openalex.org/W2181548792","https://openalex.org/W2329378669","https://openalex.org/W2331665565","https://openalex.org/W2340662778","https://openalex.org/W2345127954","https://openalex.org/W2345478270","https://openalex.org/W2414083225","https://openalex.org/W2507551277","https://openalex.org/W2535051053","https://openalex.org/W2546034113","https://openalex.org/W2564105294","https://openalex.org/W2594876201","https://openalex.org/W2610248170","https://openalex.org/W2726870238","https://openalex.org/W2732995571","https://openalex.org/W2740350782","https://openalex.org/W2742287127","https://openalex.org/W2761720379","https://openalex.org/W2765451804","https://openalex.org/W2766094333","https://openalex.org/W2771282633","https://openalex.org/W2790240881","https://openalex.org/W2791854174","https://openalex.org/W2809424912","https://openalex.org/W2885221069","https://openalex.org/W2890623685","https://openalex.org/W2895485317","https://openalex.org/W2903314971","https://openalex.org/W2906835437","https://openalex.org/W2908598638","https://openalex.org/W2910368005","https://openalex.org/W2914060533","https://openalex.org/W2914728548","https://openalex.org/W2921927631","https://openalex.org/W2972078116","https://openalex.org/W2984574901","https://openalex.org/W2986841498","https://openalex.org/W2991091521","https://openalex.org/W2991158980","https://openalex.org/W2996613942","https://openalex.org/W2999953587","https://openalex.org/W3000586503","https://openalex.org/W3000630024","https://openalex.org/W3002092157","https://openalex.org/W3010433006","https://openalex.org/W3011313923","https://openalex.org/W3011928316","https://openalex.org/W3013281133","https://openalex.org/W3014732989","https://openalex.org/W3018760278","https://openalex.org/W3023269709","https://openalex.org/W3035455223","https://openalex.org/W3081421945","https://openalex.org/W3081687173","https://openalex.org/W3085598806","https://openalex.org/W3091282491","https://openalex.org/W3094013903","https://openalex.org/W3109746568","https://openalex.org/W3113385863","https://openalex.org/W3119202143","https://openalex.org/W3119364115","https://openalex.org/W3119964701","https://openalex.org/W3138117412","https://openalex.org/W3162733120","https://openalex.org/W3170599552","https://openalex.org/W3171717313","https://openalex.org/W3175433326","https://openalex.org/W3181498685","https://openalex.org/W3188940990","https://openalex.org/W3204904362","https://openalex.org/W3205757351","https://openalex.org/W3207568982","https://openalex.org/W3211770252","https://openalex.org/W4206914132","https://openalex.org/W4224093918","https://openalex.org/W4244618912","https://openalex.org/W4281665048","https://openalex.org/W4282002836","https://openalex.org/W4283803576","https://openalex.org/W4289100982","https://openalex.org/W4308771439","https://openalex.org/W4316813226","https://openalex.org/W4327770707","https://openalex.org/W4327780974"],"related_works":["https://openalex.org/W2020398834","https://openalex.org/W3110998013","https://openalex.org/W2153489735","https://openalex.org/W2134219802","https://openalex.org/W2216824414","https://openalex.org/W4402728018","https://openalex.org/W2983832527","https://openalex.org/W3019255875","https://openalex.org/W2779573058","https://openalex.org/W2118374794"],"abstract_inverted_index":{"Nanoparticles":[0],"can":[1,16,24],"be":[2,25],"used":[3,104],"for":[4,105],"drug":[5,88,106],"delivery":[6,107],"and":[7,12,23,59,91,130],"consist":[8],"of":[9,21,31],"many":[10],"sizes":[11],"chemical":[13],"compositions.":[14],"They":[15],"accommodate":[17],"a":[18],"diverse":[19],"population":[20],"drugs":[22],"made":[26],"to":[27,57,67],"target":[28,83],"specific":[29],"areas":[30],"the":[32,79,82,92],"body.":[33],"Fabrication":[34],"methods":[35],"generally":[36],"follow":[37],"either":[38],"top-down":[39],"or":[40],"bottom-up":[41],"manufacturing":[42],"techniques,":[43],"which":[44,49,115],"have":[45,101,111],"differing":[46],"production":[47],"controls,":[48],"determine":[50],"nanoparticle":[51,93,127],"characteristics":[52],"including":[53],"but":[54],"not":[55],"limited":[56],"size":[58],"encapsulation":[60],"efficiency.":[61],"Functionalizing":[62],"these":[63],"nanoparticles":[64,80,100],"is":[65,89,94],"done":[66],"add":[68,72,75],"drugs,":[69],"prevent":[70],"aggregation,":[71],"positive":[73],"charge,":[74],"targeting,":[76],"etc.":[77],"As":[78],"reach":[81],"cells,":[84],"cellular":[85],"uptake":[86],"occurs,":[87],"released,":[90],"broken":[95],"down.":[96],"Poly(lactic-co-glycolic":[97],"acid)":[98],"(PLGA)":[99],"often":[102],"been":[103],"applications":[108],"as":[109],"they":[110],"shown":[112],"minimal":[113],"toxicity,":[114],"has":[116],"helped":[117],"with":[118],"US":[119],"FDA":[120],"approval.":[121],"This":[122],"review":[123],"breaks":[124],"down":[125],"PLGA":[126],"fabrication,":[128],"functionalization,":[129],"biological":[131],"considerations.":[132]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":5}],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2024-09-18T00:00:00"}